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Medical Forum / Diseases and Disorders / Prostate Cancer / August 2007

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FDA Not Convinced re: Lycopene & Tomatos vs. PCa

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Steve Jordan - 21 Aug 2007 23:09 GMT
Or vs. other cancers.

See: "The U.S. Food and Drug Administration's evidence-based review for
qualified health claims: tomatoes, lycopene, and cancer."

At

http://tinyurl.com/yodn5k

Regards,

Steve J
Just - 22 Aug 2007 10:22 GMT
>Or vs. other cancers.
>
[quoted text clipped - 8 lines]
>
>Steve J

Link is dead.

Try this: http://www.medicalnewstoday.com/articles/76583.php

Last paragraph: "Although it may be premature to espouse increased
consumption of tomato sauce or lycopene for prostate cancer
prevention, this area of research remains promising".

Just

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Steve Jordan - 22 Aug 2007 18:08 GMT
On August 22, Just replied to me:

> Link is dead.
>
> Try this: http://www.medicalnewstoday.com/articles/76583.php

Try this: http://tinyurl.com/23hq6w

I'd much rather get my information from the primary source than from
some reporter who may or may not be competent.

Frex, Just's quotation from the above article is not what the
researchers said, it is what the reporter says they said. Or maybe an
editorial comment.

Another way to find the abstract is to go to the Pub Med site at
http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed
and search on the abstract number, which is 17623802.

Regards,

Steve J
Just - 23 Aug 2007 00:14 GMT
>On August 22, Just replied to me:
>
[quoted text clipped - 18 lines]
>
>Steve J

Hi Steve!

On the top of the Pub Med abstract (of which you supplied a link) you
will see that they quote two comments to the abstract:

Comment in:
   J Natl Cancer Inst. 2007 Jul 18;99(14):1059.
   J Natl Cancer Inst. 2007 Jul 18;99(14):1060-2.

The second comment quoted points to an article published in the
Journal of the National Cancer Institute by Edward Giovannucci
(Affiliations of author: Department of Nutrition, Harvard School of
Public Health, Boston, MA; Department of Medicine, Brigham and Women's
Hospital/Harvard Medical School, Boston, MA). Link for this article:
http://jnci.oxfordjournals.org/cgi/content/full/99/14/1060

The article in Medical News Today (my original link) seems not to
misrepresent what Edward Giovannucci wrote:

"Given the complexities of studying the relationship between tomato or
lycopene intake and prostate cancer risk, both in terms of the
exposures and the outcome, one should not be too surprised that no
firm conclusion of benefit would be made in the FDA review. The review
was not designed to account for these issues, and the data addressing
these issues are sparse. Although it may be premature to espouse
increased consumption of tomato sauce or lycopene for prostate cancer
prevention, this area of research remains promising".

Regarding the abstract 17623802 from Pub Med, this is very succinct
(unfortunately you have to pay for the full article, also published in
the Journal of the National Cancer Institute).

Just

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Steve Jordan - 23 Aug 2007 01:13 GMT
On August 22, Just replied to me:

> On the top of the Pub Med abstract (of which you supplied a link) you
> will see that they quote two comments to the abstract:
[quoted text clipped - 9 lines]
> Hospital/Harvard Medical School, Boston, MA). Link for this article:
> http://jnci.oxfordjournals.org/cgi/content/full/99/14/1060

Yes. I've read Giovannucci's article. Very interesting. And it does
*not* support the proposition that lycopene et cetera will be helpful in
our battle.

Well, boys & girls, this is one more example of the unfortunate fact
that in this business hardly anyone agrees with anyone.

My choice is to bumble along, gobbling tomato products in my spaghetti
and other such products, and not worry about it.

I just want to let folks know that the latest fashionable dietary magic
might not be so magic, after all.

Regards,

Steve J
 
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