Medical Forum / Diseases and Disorders / Prostate Cancer / August 2007
Pump and Circumstance
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callalily - 27 Jul 2007 19:07 GMT Dear Everybody,
I have been researching penile rehabilitation for a long time. My first post on this subject, "Sex After Surgery" was written back in November, and I try to keep up with the research. If you are a man who's had surgery and want to restore or improve your erectile function, the best prospects at this moment are *injections*, with Viagra, perhaps (combination therapy).
So why are so many guys told to use the pump? Makes me want to jump out the window. Here is what a *top* expert in sexual medicine who follows men post-RP at Sloan Kettering told a patient recently.
>Thom Forbes had written:
> At that time (six weeks before surgery), Dr. Mulhall prescribed 25 >mgs. of Viagra six nights a week before bed (a 100 mg. pill cut in > fourths to save money) to increase blood flow to the > penis prior to the operation.
>At that first meeting, Dr. Mulhall and his associate, Dr. Nelson >Eddie Bennett, Jr., both made it clear that they saw no benefit in using a vacuum erection device (VED)because >it only circulated old blood. I realize there are other opinions. =====>> There is a lot we don't know about penile rehab. But this seems to be state-of-the-art treatment. Possible benefit from pre-RP injections. Still experimental. But the pump does not seem to be useful in restoring natural erectile function *because of the way it circulates blood to the penis.* I have seen info in the medical lit which says it does work, but they did not point to specifics.
Naturally, men don't like the prospect of injecting themselves, but you *can* get over it. Give yourself a chance. Also, you can have a sex life. Even if you're dead and doing your income taxes, Trimix will give you an erection.:-)
Leah
So don't say I didn't warn you.
Elzee36 - 28 Jul 2007 02:01 GMT Even if you're dead and doing your income taxes, Trimix
> will give you an erection.:-) LO Friggin L
Steve Kramer - 28 Jul 2007 03:07 GMT > Even if you're dead and doing your income taxes, Trimix >> will give you an erection.:-) > > LO Friggin L Great! Maybe I can have sex once a year, at least.... On April 15.
california_chief - 28 Jul 2007 19:56 GMT > Great! Maybe I can have sex once a year, at least.... On April 15. Who's going to do the screwing, and who's going to get screwed?
Steve Kramer - 28 Jul 2007 21:31 GMT >> Great! Maybe I can have sex once a year, at least.... On April 15. > > Who's going to do the screwing, and who's going to get screwed? Hmmmmmmm. You pose an interesting question. I guess I've been having sex once a year without trimix.
 Signature PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 PSAD .056 years Lupron 07/03 (1 mo) 8/03 and every 4 months there after PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years Casodex added daily 07/06 PSA <0.04, <0.05, <0.04 (06/12/2007) Non Illegitimi Carborundum
safire - 28 Jul 2007 05:52 GMT > Dear Everybody, > [quoted text clipped - 4 lines] > function, the best prospects at this moment are *injections*, with > Viagra, perhaps (combination therapy). Thank you for that information. I haven't researched the matter as much as you have and will keep your conclusion in mind.
> So why are so many guys told to use the pump? Makes me want to jump > out the window. Here is what a *top* expert in sexual medicine who [quoted text clipped - 3 lines] > >> At that time (six weeks before surgery), Dr. Mulhall prescribed 25 >mgs. of Viagra six nights a week before bed (a 100 mg. pill cut in
>> fourths to save money) to increase blood flow to the >> penis prior to the operation. > >> At that first meeting, Dr. Mulhall and his associate, Dr. Nelson >Eddie Bennett, Jr., both made it clear that they saw no benefit in using a vacuum erection device (VED)because
>> it only circulated old blood. I realize there are other opinions. > [quoted text clipped - 4 lines] > circulates blood to the penis.* I have seen info in the medical lit > which says it does work, but they did not point to specifics. I don't quite understand how the distinction between "circulated old blood" and (presumably) new blood affects rehabilitation. It is my understanding that the pump - by creating underpressure - stimulates blood flow to the penis and that a ring is required to prevent it from flowing back. Do injections or medicine create "new" blood? What is it that makes them more effective in rehabilitation than the pump (which as a practical matter may be less effective for its immediate purpose)?
> Naturally, men don't like the prospect of injecting themselves, but > you *can* get over it. Give yourself a chance. Also, you can have a [quoted text clipped - 4 lines] > > So don't say I didn't warn you. Ron B - 28 Jul 2007 18:44 GMT Hi Leah.
I always enjoy your posts.
Indeed...injections will for sure 'heal the sick, raise the dead' (Oh wait...that's from the song '7th Son' (Johnny Rivers.) :-)
However...I'll try to be scientific...injections will work...no doubt...because they don't rely on nerve regeneration.
They SOUND terrible...but as you say...are not so bad once you learn how to do them properly.
If "I" had a wife or heavy sexual relationship...I sure would try them.
Now...the return of function after surgery...even nerve sparing surgery...is very individual.
During surgery, even if nerves are spared...they are pulled and stretched, there are stitches...and they don't know HOW they will heal...or how long it will take.
My doc, Catalona, used to use 18 months as the time where, if there was no erectile recovery...there would NOT be.
Now...due to more data...they've extended the time to 3 years.
To ME, the most interesting thing about your post is the use of Viagra BEFORE surgery.
I understand that blood flow...via pump, shots or pills is very important.
But your comments made me think that if the chambers got full BEFORE surgery...it might help recovery AFTER surgery.
I can ask Dr. Catalona about this...but I only see him yearly. (maybe e-mail)
Thanks so much for posting this Leah.
Best of health to all,
Ron B.
Chicago
callalily - 01 Aug 2007 01:41 GMT Dear Everybody,
[*Correction to my earlier post: Oral meds like Viagra -- not injections -- are being given to patients before surgery at MSK. I have basically rewritten this post and added new info (and a joke), so please read the whole thing.**]
On Jul 27, I wrote:
I have been researching "penile rehabilitation" for a long time. My first post on this subject, "Sex After Surgery" was written back in November 2006, and I try to keep up with the research.
It's no secret that many men suffer from impotence after RP. It's hard to pin down the actual numbers, because they play games with the statistics. For example, how do you define "erectile function?" Let me count the ways. Does it include men who can have intercourse unaided or only with meds. And just how hard does the tumescence have to be? You get the picture.
Some people have no problem at all with sexual function after RP -- like the surgeon, for example (:-). Others are able to get an erection using Viagra or other oral meds. This msg is directed towards men who have not had success with the above.
There are two issues involved in "penile rehabilitation": 1) enabling a man to have an erection after surgery, and 2) helping to speed up or restore natural erectile function, thereby preventing long-term ED. I am talking about #2 here. If you are unable to have intercourse after two months, you should see an ED doctor. (For help in finding a competent one, see "Sexy Secrets For Finding An ED Doctor on my blog, prostatecancerblog.net.)
There's a lot we don't know about penile rehab, but the best prospects at this moment appear to be *injections* along with Viagra. The following is from Dr, Raina et al, renowned experts on ED:
"Early cavernosal injections following RP facilitated sexual intercourse, patient satisfaction and potentially early return of natural erections. Early combination therapy with sildenafil allowed a lower dose of intracavernous injections, minimizing the penile discomfort."
www.nature.com/ijir/journal/v18/n5/abs/3901448a.html.
*Note that there is no mention of the VED (pump).
So why are so many guys told to use the pump after RP? Makes me want to jump out the window.
Here is an example of the "gold standard" in penile rehab today. A *top* expert in sexual medicine at Sloan Kettering, Dr.John Mulhall, prescribed this for a new RP patient recently:
====>Re: *Before Surgery*
Six weeks before surgery, the patient was advised to take 25 mgs. of Viagra six nights a week, to be taken before bed (a 100 mg. pill cut in fourths to save money) to increase blood flow to the penis prior to the operation.
======> *After Surgery
*Dr. Mulhall and his associate Dr. Nelson Eddie Bennett, Jr., both made it clear that they saw no benefit in using a vacuum erection device (VED) after RP for penile rehab because it only "circulated old blood" to the penis*
Scardino says the same thing on page 366 of "The Prostate Book":
"VED's do not produce an actual physiological erection and therefore don't promote the circulation of fresh, oxygenated blood. Therefore, they may not help avoid fibrosis [scarring] after radical prostatectomy."
So even if the VED doesn't work for penile rehab, most men are told to use it anyway, with or without pills. No mention of injections (I call it "the Pinprick.")
I have seen info in the medical lit which says that the pump _does_ work for penile rehab, but they do not point to specifics. And, in the last few days, I have *again* reviewed all the articles I have about this subject, and I have not seen any proof of the above. My husband is from the "Show Me" state, so I gotta see the "beef."
I do know of one knowledgeable person online who is the moderator of a newsgroup but certainly not a doctor, who described state-of-the-art treatment for penile rehab as injections plus oral meds *and the use of the pump 15 minutes a day. I doubt there is any harm in using the pump and it can give you an erection. The thing to do is as a competent ED doctor.
Ideally, injection therapy should start about six weeks after RP. Naturally, men don't like the prospect of shooting up *there,* but you *can* get over it. Give yourself a chance. Also, you can have a sex life right away. (For more info, see the post on my blog, "How I Became the Trimix Lady.".) Even if you're dead and doing your income taxes, Trimix will give you an erection.:-)
I have to say that there is a risk of scarring or "fibrosis" from using penile injections. Some men get "Peyronie's Disease," which results in curvature of the penis. The docs say this is rare, but I don't believe it. In my husband's case, after about 8 mos. his penis kind of started to bend in the middle at a 45 degree angle. I guess the advantage is that you can fold it easily :-). (Husb has refused to consult his ED doc about this). So you have to be careful of how you inject (on both sides) and I believe you need to leave the needle in place for 5 minutes.
Remember, ask your doctor if any of this is right for you. But be sure he or she is an ED expert.
Good luck.
[Using a laptop makes me suicidal. Have been working on this about 6 hrs.]
----------------------------------------------
And just for fun: This is my favorite story in the world: how I came up with the word "pinprick" as a substitute for "injection". I was looking for a way to convey to guys that shots for ED aren't so bad after all. So I told them the injection is just a "pinprick, no big deal. I think it worked for some people.
What made me think of this word?
When I got engaged to my husband, the first thing we did was call both of our parents to tell them the news. We conferenced everybody in on the same line.
The first question my very devout mother asked after they were introduced was: "Did your son have a "Bris?" In other words, was he circumcised? Great way to get acquainted. Never heard the end of that.
His stepmother replied after a pause, "I think so, but I don't think it was done in a ritual way. A doctor did it. Isn't that right, Chuck?"
Well, my mother wasn't satisfied with this at all. She insisted that Ted had to be circumcised *properly.* So I asked her, "How can a man be circumcised twice?"
She replied, "It's no big deal -- just a ceremonial thing. All they'll do is give him a 'pinprick'. And maybe recite a blessing. Then we'll all have a little celebration."
Anyway, T. wasn't interested in having a "circumcision party," and he refused to get it done, even for me. Just to get my mother off my back.
And that's probably why he got the PC, I think. Measure for measure. He refused the "pinprick" then, and now he's getting pricked all the time.
My mother always gets her way.
Best to you all and have fun.
Leah
prostatecancerblog.net
All you need to know about PC: Get It From a Wife!
Ron B - 01 Aug 2007 18:08 GMT I was intrigued by the idea of using Viagra BEFORE surgery as it hadn't been mentioned before.
After reading the REST of your new post, I wonder about some comments.
Anything...even a pump...that brings blood into the penis is helpful.
And...the ED expert did not mention the damage done to the erectile nerves.
Even if the nerves are spared...there are so many factors that determine future erections.
As has been stated before...if the nerves had to be pulled or stretched while removing them from the prostate...THAT can affect rehab time.
If a large number of stitches are used...THAT can also affect recovery time.
So...even though the 'shots' will always help...there are a number of factors that help determine the time of the return of natural erectile function.
It may be soon, up to 3 years, or never.
Best of health to all,
Ron B.
Chicago
callalily - 05 Aug 2007 21:11 GMT Dear Ron,
It's nice talking to you, too. But I think you should be called "Professor Ron B" because you really seem to know your stuff. I just tried to organize all the stuff I have about ED at home and I found an overview of ED after RP from Johns H., so I will excerpt some pertinent parts. See # 4.
> I was intrigued by the idea of using Viagra BEFORE surgery as it hadn't > been mentioned before. ======This is experimental. It falls under the general category of "neuroprotective agents" that might prevent damage to the erectile nerves.
> After reading the REST of your new post, I wonder about some comments. > > Anything...even a pump...that brings blood into the penis is helpful. ===== I did not say that.
> And...the ED expert did not mention the damage done to the erectile > nerves. Even if the nerves are spared...there are so many factors that determine [quoted text clipped - 6 lines] > factors that help determine the time of the return of natural erectile > function. ====== True. I just couldn't include everything. Here's something on potential damage from surgery from Hopkins. Am excerpting a few things.
"Erectile Dysfunction Following RP"
<snip>
"However, despite expert application of the nerve-sparing prostatectomy technique, early recovery of natural erectile function is not common. Increasing attention has been given to this problem in recent years with the advancement of possible new therapeutic options to enhance erection function recovery following this surgery. Visit Dr. Burnett's Neuro-Urology Laboratory
This topic area was handled thoroughly in an article written by Dr. Arthur L. Burnett, entitled "Erectile Dysfunction Following Radical Prostatectomy," published in the Journal of the American Medical Association, June 1, 2005. Using a question and answer format, excerpts from this article are provided below.
[Has a good illustration of erectile nerves (close-up) for those who are visually oriented.]
<snip>
2. What are the current expectations with regard to outcomes after radical prostatectomy?
Following a series of anatomical discoveries of the prostate and its surrounding structures about 2 decades ago, changes in the surgical approach permitted the procedure to be performed with significantly improved outcomes.
* Now after the surgery, expectations are that physical capacity is fully recovered in most patients within several weeks, return of urinary continence is achieved by more than 95% of patients within a few months, and erection recovery with ability to engage in sexual intercourse is regained by most patients with or without oral phosphodiesterase 5 (PDE5) inhibitors within 2 years. *
<snip>
4. Why does it take so long to recover erections after the very best surgery?
A number of explanations have been proposed for this phenomenon of delayed recovery, including mechanically induced nerve stretching that may occur during prostate retraction, thermal damage to nerve tissue caused by electrocoagulative cautery during surgical dissection, injury to nerve tissue amid attempts to control surgical bleeding, and local inflammatory effects associated with surgical trauma.
<snip>
7. Is another treatment option better for preservation of erectile function?
The growing interest in pelvic radiation, including brachytherapy, as an alternative to surgery can be attributed in part to the supposition that surgery carries a higher risk of erectile dysfunction.
<snip>
9. Can erection "rehabilitation" be applied to improve erection recovery rates?
A relatively new strategy in clinical management after radical prostatectomy has arisen from the idea that early induced sexual stimulation and blood flow in the penis may facilitate the return of natural erectile function and resumption of medically unassisted sexual activity. There is an interest in using oral PDE5 inhibitors for this purpose, since this therapy is noninvasive, convenient, and highly tolerable. However, while the early, regular use of PDE5 inhibitors or other currently available, "on-demand" therapies is widely touted after surgery for purposes of erection rehabilitation, such therapy is mainly empiric. Evidence for its success remains limited.
10. Are there new strategies in the near future that may be helpful in improving erection recovery after surgery?
<snip>
Neuromodulatory therapy, represents an exciting, rapidly developing approach to revitalize intact nerves and promote nerve growth. Therapeutic prospects include neurotrophins, neuroimmunophilin ligands, neuronal cell death inhibitors, nerve guides, tissue engineering/stem cell therapy, electrical stimulation, and even gene therapy.
>>>>>> It may be soon, up to 3 years, or never. I have heard stories of EF returning after this period. It's just less common.
Take care.
Leah
prostatecancerblog.net
today: notes from cancerworld (humor)
callalily - 05 Aug 2007 20:11 GMT > Dear Everybody, Sorry, folks, I have to make another *very important correction* to make here. I misunderstood something. This is the first time I allowed myself to improvise a little, and it won't happen again. I wrote:
>>>> So you have to be careful of how you inject (on both sides) and I >>>>>believe *you need to leave the needle in place for 5 minutes.* A long-time user of injections informed me that you should **not** leave the needle in place for five minutes." I am going to cite what he told me because I haven't had the time yet to research the mechanics of injecting myself. This man seems to know what he's talking about -- calls himself the "injection zealot". But more important, he has used injections successfully himself for five years. So remember, this is just advice from another *patient.*
You have to check with your doctor about *everything*. I have no medical credentials at all.
Just trying to help. ---------------------------------------------------------
>From Michael: "I have been following certain protocols for injection for over five years and have no scarring, bending or other abnormalities and you can usually never find the injection site a few hours after the fact.
It IS possible to have problems from injections. The biggest problem is if you build up scar tissue at injection sites due to improper technique. You mention leaving the needle in for 5 minutes. NO - please don't!!
Try to inject slowly, so it takes at least 30 seconds to push the plunger, as Bill M. recently posted. Try to last 60 seconds if you are using 70 units or more.
Here is the MOST IMPORTANT THING: hold firm pressure on the injection site for AT LEAST 5 MINUTES, more if the injection site is still bleeding.
I also always take two "breaks" in the 5 minute period and roll the penis between my palms to distribute the meds evenly, and then add 30 seconds to make up for the time that takes.
My doc says it is much more important to hold pressure on the injection site as described above than to switch sides.
In medical practice, one generally uses the lightest gauge and length needle that will do the job, in order to reduce tissue damage. I use 5/16" by 31 gauge needles and find there is less bruising or bleeding than if I use 3/8" or 1/2" needles.
You all know that I am an injection therapy zealot. I believe that most guys that "fail" at injections could succeed with a good coach.
Also, by the way: Just another patient opinion:
I agree with you on the VED. I use it because it seems to give a good physical stretch, but as far as therapeutic penile rehab goes, erections from injections and erections from oral meds seem to be the most supported by the literature, and it makes good sense as well.
I, too, hate that a lot of surgeons just point their patients to a VED and nothing else or make injections seem like an exotic last resort.
----------------------------------------------------
Best,
Leah
prostatecancerblog.net
Today: Humor: "From Cancerworld."
callalily - 06 Aug 2007 01:35 GMT > Dear Everybody, Sorry, folks, I have to make another *very important correction* to make here. I misunderstood something. This is the first time I allowed myself to improvise a little, and it won't happen again. I wrote:
>>>> So you have to be careful of how you inject (on both sides) and I >>>>>believe *you need to leave the needle in place for 5 minutes.* A long-time user of injections informed me that you should **not** leave the needle in place for five minutes." I am going to cite what he told me because I haven't had the time yet to research the mechanics of injecting myself. This man seems to know what he's talking about -- calls himself the "injection zealot". But more important, he has used injections successfully himself for five years. So remember, this is just advice from another *patient.*
You have to check with your doctor about *everything*. I have no medical credentials at all.
Just trying to help. ---------------------------------------------------------
>From Michael: "I have been following certain protocols for injection for over five years and have no scarring, bending or other abnormalities and you can usually never find the injection site a few hours after the fact.
It IS possible to have problems from injections. The biggest problem is if you build up scar tissue at injection sites due to improper technique. You mention leaving the needle in for 5 minutes. NO - please don't!!
Try to inject slowly, so it takes at least 30 seconds to push the plunger, as Bill M. recently posted. Try to last 60 seconds if you are using 70 units or more.
Here is the MOST IMPORTANT THING: hold firm pressure on the injection site for AT LEAST 5 MINUTES, more if the injection site is still bleeding.
I also always take two "breaks" in the 5 minute period and roll the penis between my palms to distribute the meds evenly, and then add 30 seconds to make up for the time that takes.
My doc says it is much more important to hold pressure on the injection site as described above than to switch sides.
In medical practice, one generally uses the lightest gauge and length needle that will do the job, in order to reduce tissue damage. I use 5/16" by 31 gauge needles and find there is less bruising or bleeding than if I use 3/8" or 1/2" needles.
You all know that I am an injection therapy zealot. I believe that most guys that "fail" at injections could succeed with a good coach.
Also, by the way: Just another patient opinion:
I agree with you on the VED. I use it because it seems to give a good physical stretch, but as far as therapeutic penile rehab goes, erections from injections and erections from oral meds seem to be the most supported by the literature, and it makes good sense as well.
I, too, hate that a lot of surgeons just point their patients to a VED and nothing else or make injections seem like an exotic last resort."
----------------------------------------------------
Best,
Leah
prostatecancerblog.net
Today: Humor: "Notes From Cancerworld."
> Leah > > prostatecancerblog.net > > All you need to know about PC: Get It From a Wife!
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