Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / Diseases and Disorders / Prostate Cancer / August 2007

Tip: Looking for answers? Try searching our database.

Pump and Circumstance

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
callalily - 27 Jul 2007 19:07 GMT
Dear Everybody,

I have been researching penile rehabilitation for a long time.  My
first post on this subject, "Sex After Surgery" was written back in
November, and I try to keep up with the research.  If you are a man
who's had surgery and want to restore or improve your erectile
function, the best prospects at this moment are *injections*, with
Viagra, perhaps (combination therapy).

So why are so many guys told to use the pump?  Makes me want to jump
out the window.  Here is what a *top* expert in sexual medicine who
follows men post-RP at Sloan Kettering told a patient recently.

>Thom Forbes had written:

> At that time (six weeks before surgery), Dr. Mulhall prescribed 25 >mgs. of Viagra six nights a week before bed (a 100 mg. pill cut in
> fourths to save money) to increase blood flow to the
> penis prior to the operation.

>At that first meeting, Dr. Mulhall and his associate, Dr. Nelson >Eddie Bennett, Jr., both made it clear that they saw no benefit in using a vacuum erection device (VED)because
>it only circulated old blood. I realize there are other opinions.

=====>> There is a lot we don't know about penile rehab.  But this
seems to be state-of-the-art treatment.  Possible benefit from pre-RP
injections.  Still experimental.  But the pump does not seem to be
useful in restoring natural erectile function *because of the way it
circulates blood to the penis.*  I have seen info in the medical lit
which says it does work, but they did not point to specifics.

Naturally, men don't like the prospect of injecting themselves, but
you *can* get over it.  Give yourself a chance.  Also, you can have a
sex life.  Even if you're dead and doing your income taxes, Trimix
will give you an erection.:-)

Leah

So don't say I didn't warn you.
Elzee36 - 28 Jul 2007 02:01 GMT
Even if you're dead and doing your income taxes, Trimix
> will give you an erection.:-)

 LO Friggin L
Steve Kramer - 28 Jul 2007 03:07 GMT
> Even if you're dead and doing your income taxes, Trimix
>> will give you an erection.:-)
>
>  LO Friggin L

Great!  Maybe I can have sex once a year, at least....  On April 15.
california_chief - 28 Jul 2007 19:56 GMT
> Great!  Maybe I can have sex once a year, at least....  On April 15.

Who's going to do the screwing, and who's going to get screwed?
Steve Kramer - 28 Jul 2007 21:31 GMT
>> Great!  Maybe I can have sex once a year, at least....  On April 15.
>
> Who's going to do the screwing, and who's going to get screwed?

Hmmmmmmm.  You pose an interesting question.  I guess I've been having sex
once a year without trimix.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  <.1  <.1  <.1  .27  .37  .75            PSAD 0.19 years
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32                       PSAD .056 years
Lupron 07/03 (1 mo) 8/03 and every 4 months there after
PSA  .07 .05 .06 .09 .08 .132 .145       PSAD 1.4 years
Casodex added daily 07/06
PSA <0.04, <0.05, <0.04 (06/12/2007)
Non Illegitimi Carborundum

safire - 28 Jul 2007 05:52 GMT
> Dear Everybody,
>
[quoted text clipped - 4 lines]
> function, the best prospects at this moment are *injections*, with
> Viagra, perhaps (combination therapy).

Thank you for that information. I haven't researched the matter as much
as you have and will keep your conclusion in mind.

> So why are so many guys told to use the pump?  Makes me want to jump
> out the window.  Here is what a *top* expert in sexual medicine who
[quoted text clipped - 3 lines]
>
>> At that time (six weeks before surgery), Dr. Mulhall prescribed 25 >mgs.

of Viagra six nights a week before bed (a 100 mg. pill cut in
>> fourths to save money) to increase blood flow to the
>> penis prior to the operation.
>
>> At that first meeting, Dr. Mulhall and his associate, Dr. Nelson >Eddie Bennett, Jr.,

both made it clear that they saw no benefit in using a vacuum erection
device (VED)because
>> it only circulated old blood. I realize there are other opinions.
>
[quoted text clipped - 4 lines]
> circulates blood to the penis.*  I have seen info in the medical lit
> which says it does work, but they did not point to specifics.

I don't quite understand how the distinction between "circulated old
blood" and (presumably) new blood affects rehabilitation. It is my
understanding that the pump - by creating underpressure - stimulates
blood flow to the penis and that a ring is required to prevent it from
flowing back. Do injections or medicine create "new" blood? What is it
that makes them more effective in rehabilitation than the pump (which as
a practical matter may be less effective for its immediate purpose)?

> Naturally, men don't like the prospect of injecting themselves, but
> you *can* get over it.  Give yourself a chance.  Also, you can have a
[quoted text clipped - 4 lines]
>
> So don't say I didn't warn you.
Ron B - 28 Jul 2007 18:44 GMT
Hi Leah.

I always enjoy your posts.

Indeed...injections will for sure 'heal the sick, raise the dead' (Oh
wait...that's from the song '7th Son' (Johnny Rivers.) :-)

However...I'll try to be scientific...injections will work...no
doubt...because they don't rely on nerve regeneration.

They SOUND terrible...but as you say...are not so bad once you learn how
to do them properly.

If "I" had a wife or heavy sexual relationship...I sure would try them.

Now...the return of function after surgery...even nerve sparing
surgery...is very individual.

During surgery, even if nerves are spared...they are pulled and
stretched, there are stitches...and they don't know HOW they will
heal...or how long it will take.

My doc, Catalona, used to use 18 months as the time where, if there was
no erectile recovery...there would NOT be.

Now...due to more data...they've extended the time to 3 years.

To ME, the most interesting thing about your post is the use of Viagra
BEFORE surgery.

I understand that blood flow...via pump, shots or pills is very
important.

But your comments made me think that if the chambers got full BEFORE
surgery...it might help recovery AFTER surgery.

I can ask Dr. Catalona about this...but I only see him yearly. (maybe
e-mail)

Thanks so much for posting this Leah.

Best of health to all,

Ron B.

Chicago
callalily - 01 Aug 2007 01:41 GMT
Dear Everybody,

[*Correction to my earlier post: Oral meds like Viagra -- not
injections -- are being given to patients before surgery at MSK.  I
have basically rewritten this post and added new info (and a joke), so
please read the whole thing.**]

On Jul 27, I wrote:

I have been researching "penile rehabilitation" for a long time.  My
first post on this subject, "Sex After Surgery" was written back in
November 2006, and I try to keep up with the research.

It's no secret that many men suffer from impotence after RP.  It's
hard to pin down the actual numbers, because they play games with the
statistics.  For example, how do you define "erectile function?"  Let
me count the ways.  Does it include men who can have intercourse
unaided or only with meds.  And just how hard does the tumescence have
to be? You get the picture.

Some people have no problem at all with sexual function after RP --
like the surgeon, for example (:-).  Others are able to get an
erection using Viagra or other oral meds.   This msg is directed
towards men who have not had success with the above.

There are two issues involved in "penile rehabilitation": 1) enabling
a man to have an erection after surgery, and 2) helping to speed up or
restore natural erectile function, thereby preventing long-term ED.  I
am talking about #2 here.
If you are unable to have intercourse after two months, you should see
an ED doctor.  (For help in finding a competent one, see "Sexy Secrets
For Finding An ED Doctor on my blog, prostatecancerblog.net.)

There's a lot we don't know about penile rehab, but the best prospects
at this moment appear to be *injections* along with Viagra.  The
following is from Dr, Raina et al, renowned experts on ED:

"Early cavernosal injections following RP facilitated sexual
intercourse, patient satisfaction and potentially early return of
natural erections. Early combination therapy with sildenafil allowed a
lower dose of intracavernous injections, minimizing the penile
discomfort."

www.nature.com/ijir/journal/v18/n5/abs/3901448a.html.

*Note that there is no mention of the VED (pump).

So why are so many guys told to use the pump after RP?  Makes me want
to jump out the window.

Here is an example of the "gold standard" in penile rehab today.  A
*top* expert in sexual medicine at Sloan Kettering, Dr.John Mulhall,
prescribed this for a new RP patient recently:

====>Re:  *Before Surgery*

Six weeks before surgery, the patient was advised to take 25 mgs. of
Viagra six nights a week, to be taken before bed (a 100 mg. pill cut
in fourths to save money) to increase blood flow to the penis prior to
the operation.

======> *After Surgery

*Dr. Mulhall and his associate Dr. Nelson Eddie Bennett, Jr., both
made it clear that they saw no benefit in using a vacuum erection
device (VED) after RP for penile rehab because it only "circulated old
blood" to the penis*

Scardino says the same thing on page 366 of "The Prostate Book":

"VED's do not produce an actual physiological erection and therefore
don't promote the circulation of fresh, oxygenated blood.   Therefore,
they may not help avoid fibrosis [scarring] after radical
prostatectomy."

So even if the VED doesn't work for penile rehab, most men are told to
use it anyway, with or without pills.  No mention of injections (I
call it "the Pinprick.")

I have seen info in the medical lit which says that the pump _does_
work for penile rehab, but they do not point to specifics. And, in the
last few days, I have *again* reviewed all the articles I have about
this subject, and I have not seen any proof of the above.  My husband
is from the "Show Me" state, so I gotta see the "beef."

I do know of one knowledgeable person online who is the moderator of a
newsgroup but certainly not a doctor, who described state-of-the-art
treatment for penile rehab as injections plus oral meds *and the use
of the pump 15 minutes a day.  I doubt there is any harm in using the
pump and it can give you an erection.  The thing to do is as a
competent ED doctor.

Ideally, injection therapy should start about six weeks after RP.
Naturally, men don't like the prospect of shooting up *there,* but you
*can* get over it.  Give yourself a chance.  Also, you can have a sex
life right away.  (For more info, see the post on my blog, "How I
Became the Trimix Lady.".)  Even if you're dead and doing your income
taxes, Trimix will give you an erection.:-)

I have to say that there is a risk of scarring or "fibrosis" from
using penile injections. Some men get "Peyronie's Disease," which
results in curvature of the penis. The docs say this is rare, but I
don't believe it.  In my husband's case, after about 8 mos. his penis
kind of started to bend in the middle at a 45 degree angle.  I guess
the advantage is that you can fold it easily :-).  (Husb has refused
to consult his ED doc about this). So you have to be careful of how
you inject (on both sides) and I believe you need to leave the needle
in place for 5 minutes.

Remember, ask your doctor if any of this is right for you.  But be
sure he or she is an ED expert.

Good luck.

[Using a laptop makes me suicidal.  Have been working on this about 6
hrs.]

----------------------------------------------

And just for fun: This is my favorite story in the world: how I came
up with the word "pinprick" as a substitute for "injection".  I was
looking for a way  to convey to guys that shots for ED aren't so bad
after all.  So I told them the injection is just a "pinprick, no big
deal. I think it worked for some people.

What made me think of this word?

When I got engaged to my husband, the first thing we did was call both
of our parents to tell them the news.  We conferenced everybody in on
the same line.

The first question my very devout mother asked after they were
introduced was: "Did your son have a "Bris?" In other words, was he
circumcised?  Great way to get acquainted.  Never heard the end of
that.

His stepmother replied after a pause, "I think so, but I don't think
it was done in a ritual way.  A doctor did it. Isn't that right,
Chuck?"

Well, my mother wasn't satisfied with this at all.  She insisted that
Ted had to be circumcised *properly.*  So I asked her, "How can a man
be circumcised twice?"

She replied, "It's no big deal -- just a ceremonial thing.  All
they'll do is give him a 'pinprick'.   And maybe recite a blessing.
Then we'll all have a little celebration."

Anyway, T. wasn't interested in having a "circumcision party," and he
refused to get it done, even for me.  Just to get my mother off my
back.

And that's probably why he got the PC, I think.  Measure for measure.
He refused the "pinprick"  then, and now he's getting pricked all the
time.

My mother always gets her way.

Best to you all and have fun.

Leah

prostatecancerblog.net

All you need to know about PC: Get It From a Wife!
Ron B - 01 Aug 2007 18:08 GMT
I was intrigued by the idea of using Viagra BEFORE surgery as it hadn't
been mentioned before.

After reading the REST of your new post, I wonder about some comments.

Anything...even a pump...that brings blood into the penis is helpful.

And...the ED expert did not mention the damage done to the erectile
nerves.

Even if the nerves are spared...there are so many factors that determine
future erections.

As has been stated before...if the nerves had to be pulled or stretched
while removing them from the prostate...THAT can affect rehab time.

If a large number of stitches are used...THAT can also affect recovery
time.

So...even though the 'shots' will always help...there are a number of
factors that help determine the time of the return of natural erectile
function.

It may be soon, up to 3 years, or never.

Best of health to all,

Ron B.

Chicago
callalily - 05 Aug 2007 21:11 GMT
Dear Ron,

It's nice talking to you, too.  But I think you should be called
"Professor Ron B" because you really seem to know your stuff.  I just
tried to organize all the stuff I have about ED at home and I found an
overview of ED after RP from Johns H., so I will excerpt some
pertinent parts. See # 4.

> I was intrigued by the idea of using Viagra BEFORE surgery as it hadn't
> been mentioned before.

======This is experimental.  It falls under the general category of
"neuroprotective agents" that might prevent damage to the erectile
nerves.

> After reading the REST of your new post, I wonder about some comments.
>
> Anything...even a pump...that brings blood into the penis is helpful.

===== I did not say that.

> And...the ED expert did not mention the damage done to the erectile
> nerves. Even if the nerves are spared...there are so many factors that determine
[quoted text clipped - 6 lines]
> factors that help determine the time of the return of natural erectile
> function.

====== True.  I just couldn't include everything.  Here's something on
potential damage from surgery from Hopkins.  Am excerpting a few
things.

"Erectile Dysfunction Following RP"

<snip>

"However, despite expert application of the nerve-sparing
prostatectomy technique, early recovery of natural erectile function
is not common. Increasing attention has been given to this problem in
recent years with the advancement of possible new therapeutic options
to enhance erection function recovery following this surgery. Visit
Dr. Burnett's Neuro-Urology Laboratory

This topic area was handled thoroughly in an article written by Dr.
Arthur L. Burnett, entitled "Erectile Dysfunction Following Radical
Prostatectomy," published in the Journal of the American Medical
Association, June 1, 2005. Using a question and answer format,
excerpts from this article are provided below.

[Has a good illustration of erectile nerves (close-up) for those who
are visually oriented.]

<snip>

2. What are the current expectations with regard to outcomes after
radical prostatectomy?

Following a series of anatomical discoveries of the prostate and its
surrounding structures about 2 decades ago, changes in the surgical
approach permitted the procedure to be performed with significantly
improved outcomes.

* Now after the surgery, expectations are that physical capacity is
fully recovered in most patients within several weeks, return of
urinary continence is achieved by more than 95% of patients within a
few months, and erection recovery with ability to engage in sexual
intercourse is regained by most patients with or without oral
phosphodiesterase 5 (PDE5) inhibitors within 2 years. *

<snip>

4. Why does it take so long to recover erections after the very best
surgery?

A number of explanations have been proposed for this phenomenon of
delayed recovery, including mechanically induced nerve stretching that
may occur during prostate retraction, thermal damage to nerve tissue
caused by electrocoagulative cautery during surgical dissection,
injury to nerve tissue amid attempts to control surgical bleeding, and
local inflammatory effects associated with surgical trauma.

<snip>

7. Is another treatment option better for preservation of erectile
function?

The growing interest in pelvic radiation, including brachytherapy, as
an alternative to surgery can be attributed in part to the supposition
that surgery carries a higher risk of erectile dysfunction.

<snip>

9. Can erection "rehabilitation" be applied to improve erection
recovery rates?

A relatively new strategy in clinical management after radical
prostatectomy has arisen from the idea that early induced sexual
stimulation and blood flow in the penis may facilitate the return of
natural erectile function and resumption of medically unassisted
sexual activity. There is an interest in using oral PDE5 inhibitors
for this purpose, since this therapy is noninvasive, convenient, and
highly tolerable. However, while the early, regular use of PDE5
inhibitors or other currently available, "on-demand" therapies is
widely touted after surgery for purposes of erection rehabilitation,
such therapy is mainly empiric. Evidence for its success remains
limited.

10. Are there new strategies in the near future that may be helpful in
improving erection recovery after surgery?

<snip>

Neuromodulatory therapy, represents an exciting, rapidly developing
approach to revitalize intact nerves and promote nerve growth.
Therapeutic prospects include neurotrophins, neuroimmunophilin
ligands, neuronal cell death inhibitors, nerve guides, tissue
engineering/stem cell therapy, electrical stimulation, and even gene
therapy.

>>>>>> It may be soon, up to 3 years, or never.

I have heard stories of EF returning after this period.  It's just
less common.

Take care.

Leah

prostatecancerblog.net

today: notes from cancerworld (humor)
callalily - 05 Aug 2007 20:11 GMT
> Dear Everybody,

Sorry, folks, I have to make another *very important correction* to
make here.  I misunderstood something.  This is the first time I
allowed myself to improvise a little, and it won't happen again.  I
wrote:

>>>> So you have to be careful of how you inject (on both sides) and I >>>>>believe *you need to leave the needle in place for 5 minutes.*

A long-time user of injections informed me that you should **not**
leave the needle in place for five minutes."  I am going to cite what
he told me because I haven't had the time yet to research the
mechanics of injecting myself.  This man seems to know what he's
talking about -- calls himself the "injection zealot".  But more
important, he has used injections successfully himself for five years.
So remember, this is just advice from another *patient.*

You have to check with your doctor about *everything*.   I have no
medical credentials at all.

Just trying to help.
---------------------------------------------------------
>From Michael:

"I have been following certain protocols for injection for over five
years and
have no scarring, bending or other abnormalities and you can usually
never
find the injection site a few hours after the fact.

It IS possible to have problems from injections. The biggest problem
is if
you build up scar tissue at injection sites due to improper technique.
You
mention leaving the needle in for 5 minutes. NO - please don't!!

Try to inject slowly, so it takes at least 30 seconds to push the
plunger,
as Bill M. recently posted. Try to last 60 seconds if you are using
70
units or more.

Here is the MOST IMPORTANT THING: hold firm pressure on the injection
site for AT LEAST 5 MINUTES, more if the injection site is still
bleeding.

I also always take two "breaks" in the 5 minute period and roll the
penis
between my palms to distribute the meds evenly, and then add 30
seconds to make up for the time that takes.

My doc says it is much more important to hold pressure on the
injection site as described above than to switch sides.

In medical practice, one generally uses the lightest gauge and length
needle that will do the job, in order to reduce tissue damage. I use
5/16" by 31 gauge needles and find there is less bruising or bleeding
than if I use 3/8" or 1/2" needles.

You all know that I am an injection therapy zealot. I believe that
most guys
that "fail" at injections could succeed with a good coach.

Also, by the way:  Just another patient opinion:

I agree with you on the VED. I use it because it seems to give a good
physical stretch, but as far as therapeutic penile rehab goes,
erections
from injections and erections from oral meds seem to be the most
supported by the literature, and it makes good sense as well.

I, too, hate that a lot of surgeons just point their patients to a VED
and
nothing else or make injections seem like an exotic last resort.

----------------------------------------------------

Best,

Leah

prostatecancerblog.net

Today: Humor: "From Cancerworld."
callalily - 06 Aug 2007 01:35 GMT
> Dear Everybody,

Sorry, folks, I have to make another *very important correction* to
make here.  I misunderstood something.  This is the first time I
allowed myself to improvise a little, and it won't happen again.  I
wrote:

>>>> So you have to be careful of how you inject (on both sides) and I >>>>>believe *you need to leave the needle in place for 5 minutes.*

A long-time user of injections informed me that you should **not**
leave the needle in place for five minutes."  I am going to cite what
he told me because I haven't had the time yet to research the
mechanics of injecting myself.  This man seems to know what he's
talking about -- calls himself the "injection zealot".  But more
important, he has used injections successfully himself for five years.
So remember, this is just advice from another *patient.*

You have to check with your doctor about *everything*.   I have no
medical credentials at all.

Just trying to help.
---------------------------------------------------------
>From Michael:

"I have been following certain protocols for injection for over five
years and
have no scarring, bending or other abnormalities and you can usually
never
find the injection site a few hours after the fact.

It IS possible to have problems from injections. The biggest problem
is if
you build up scar tissue at injection sites due to improper technique.
You
mention leaving the needle in for 5 minutes. NO - please don't!!

Try to inject slowly, so it takes at least 30 seconds to push the
plunger,
as Bill M. recently posted. Try to last 60 seconds if you are using
70
units or more.

Here is the MOST IMPORTANT THING: hold firm pressure on the injection
site for AT LEAST 5 MINUTES, more if the injection site is still
bleeding.

I also always take two "breaks" in the 5 minute period and roll the
penis
between my palms to distribute the meds evenly, and then add 30
seconds to make up for the time that takes.

My doc says it is much more important to hold pressure on the
injection site as described above than to switch sides.

In medical practice, one generally uses the lightest gauge and length
needle that will do the job, in order to reduce tissue damage. I use
5/16" by 31 gauge needles and find there is less bruising or bleeding
than if I use 3/8" or 1/2" needles.

You all know that I am an injection therapy zealot. I believe that
most guys
that "fail" at injections could succeed with a good coach.

Also, by the way:  Just another patient opinion:

I agree with you on the VED. I use it because it seems to give a good
physical stretch, but as far as therapeutic penile rehab goes,
erections
from injections and erections from oral meds seem to be the most
supported by the literature, and it makes good sense as well.

I, too, hate that a lot of surgeons just point their patients to a VED
and
nothing else or make injections seem like an exotic last resort."

----------------------------------------------------

Best,

Leah

prostatecancerblog.net

Today: Humor: "Notes From Cancerworld."

> Leah
>
> prostatecancerblog.net
>
> All you need to know about PC: Get It From a Wife!
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2008 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.