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Medical Forum / Diseases and Disorders / Prostate Cancer / July 2007

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The Latest on Tx

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Steve Jordan - 25 Jul 2007 23:54 GMT
From Medscape, a review of PCa tx news from the recent ASCO (American
Society for Clinical Oncology) meeting:

http://www.medscape.com/viewarticle/559836?src=mp

Regards,

Steve J
Alan Meyer - 27 Jul 2007 01:19 GMT
>  From Medscape, a review of PCa tx news from the recent ASCO (American
> Society for Clinical Oncology) meeting:
>
> http://www.medscape.com/viewarticle/559836?src=mp

I finally got around to reading this.  If I read it correctly,
some interesting conclusions were:

1. Longer hormone therapy (3 years) after radiation extends life
  for more patients than does shorter therapy (6 months).

2. Patients on long term hormone therapy did not have worse
  "global health" than patients on short term therapy.  My
  interpretation: Hormone therapy will _not_ kill you or make
  you sick.

3. Intermittent therapy did at least as well as non-intermittent
  therapy.  The numbers were actually significantly better for
  intermittent therapy, but the study population size was too
  small to conclude too much from it.

4. Satraplatin, a new chemotherapy agent, extended survival for a
  significant number of patients who had become resistant to
  docetaxel.

5. A couple of new, novel, drugs (irofulven and abiraterone)
  appeared to extend life in HRPC.

6. A new type of whole body radiation appears to be useful both
  in palliating bone pain and in extending life for men with
  metastatic disease.  Radioactive chemicals are administered
  that tend to concentrate in bones and deliver the radiation
  there.

If someone reads the abstract and disagrees with my summary,
please correct me.

   Alan
chasjac - 27 Jul 2007 17:09 GMT
[snip]
> If someone reads the abstract and disagrees with my summary,
> please correct me.

Looks like a good summary to me.

I love that the researchers went into the short-term vs. longer-term
ADT study with one hypothesis and wound up showing the opposite.  I
have been hesitant to include examples about prostate cancer in my
stats course, but I think I must put this one in when we discuss
hypothesis testing.

--charlie

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