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Medical Forum / Diseases and Disorders / Prostate Cancer / July 2007Vitamins: Mega-doses lead to PCa
Doing Harm to the Prostate May 15, 2007 6:00 PM WASHINGTON, D.C. -- A new study is linking high-doses of vitamins to advanced prostate cancer. The study finds that taking too many vitamins may raise a man's risk of dying from the disease. The research doesn't settle the issue, but it's being called the biggest study yet to suggest high-dose multivitamins may harm the prostate. The study found no link between multivitamin use and early-stage prostate cancer. Researchers speculate that high-dose vitamins may have little effect until a tumor appears, and then could spur its growth. The study tracked the diet and health of almost 300-thousand men over more than five years. It's being published in tomorrow's Journal of the National Cancer Institute. > Doing Harm to the Prostate > May 15, 2007 6:00 PM [quoted text clipped - 16 lines] > over more than five years. It's being published in tomorrow's > Journal of the National Cancer Institute. From the JNCI website, reporting on a study of about 300,000 older men: "No association was observed between multivitamin use and risk of localized prostate cancer. However, we found an increased risk of advanced and fatal prostate cancers...when compared with never users. "The incidence rates per 100,000 person-years for advanced and fatal prostate cancers for those who took a multivitamin more than seven times per week were 143.8 and 18.9, respectively, compared with 113.4 and 11.4 in never users. The positive associations with excessive multivitamin use were strongest in men with a family history of prostate cancer or who took individual micronutrient supplements, including selenium, -carotene, or zinc. "Conclusion: These results suggest that regular multivitamin use is not associated with the risk of early or localized prostate cancer. The possibility that men taking high levels of multivitamins along with other supplements have increased risk of advanced and fatal prostate cancers is of concern and merits further evaluation." http://jnci.oxfordjournals.org/cgi/content/abstract/99/10/754 Alex |
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