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zazu - 04 Apr 2007 17:27 GMT

my father is patient of prostate and bone metasis.his PSA lying
between 0.33-4001 in last 5 years..he is now honvan and inj ZOLDERIA..
1..now oncocoligest prescribed ESTRACYT which is too-too costly for
lower middlel class family like us...
2..may anyone help us to get ESTRCYT in discounted rate..i dont want a
single rs as donation but wants only ESTRCYT..may anyone help me to
save my father..
3..he feels pain in legs now and inj ZOLDERIA not works this month
4.. how much inj ZOLDERIA can a man take?we inject 21 inj till
now,may we stop or scontinue with the same??
pls guide

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Steve Jordan - 05 Apr 2007 01:46 GMT

> my father is patient of prostate and bone metasis.his PSA lying
> between 0.33-4001 in last 5 years..

Regarding the PSA, what are the measurement units? Nanograms per
milliliter (ng/mL) or nanomols (nm)? It is important to know this.

Is he in Europe?

What is his clinical history? Age, general health, Gleason score on
biopsy, clinical stage (sometimes called T-stage) -- for example T2c or T3b?

What is his treatment history? Surgery? Radiation (what type)? Other?

> he is now honvan and inj ZOLDERIA..

Honvan is fosfestrol tetrasodium, a synthetic oestrogen (female sex
hormone) that is used in the treatment of prostate cancer. It is not
used in the USA.

I cannot find a listing for "Zolderia." But, searching rxlist.com, I
find Zometa (zolderonic acid or zolendrodate), which is often prescribed
at a dosage of 4 mg monthly for bone metastases.

> 1..now oncocoligest prescribed ESTRACYT which is too-too costly for
> lower middlel class family like us...

Estracyt is known in the USA and Canada as Emcyt (estramustine). It is
used as a palliative treatment of prostate cancer. That means that it is
not intended to cure, but to relieve symptoms.

> 2..may anyone help us to get ESTRCYT in discounted rate..i dont want a
> single rs as donation but wants only ESTRCYT..may anyone help me to
> save my father..

The manufacturer is Pfizer. They have a program for uninsured patients
who are unable to afford their products.
See, http://www.pfizer.com/pfizer/subsites/philanthropy/access/index.jsp

> 3..he feels pain in legs now and inj ZOLDERIA not works this month

I do not know the answer. I suggest asking his doctor.

> 4.. how much inj ZOLDERIA can a man take?we inject 21 inj till
> now,may we stop or scontinue with the same??
> pls guide

The usual dose is 4 mg given every 28 days over no less than 15 minutes.
"21" what? What is the measurement unit?

I am not a medical doctor, but I recommend that stopping Zolderia
(Zometa) not be done without advice of the doctor. I think that it would
be a mistake, but my medical advice is worthless.

A thorough review of Zometa can be found at
http://www.rxlist.com/cgi/generic/zometa.htm

Good luck.

Regards,

Steve J

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Heather - 05 Apr 2007 03:17 GMT

Steve......I ran a Whois search and this man is in or near New Delhi,
India. He has posted before. I was trying to remember his nationality,
but got a clue when he said he didn't want a "single rs"......rupees I
would assume.

Steve Kramer......do you remember this fellow?? And I take it that his
PSA went from 0.33 UP TO 4001 in 5 years. That rang a bell too.

Heather

>> my father is patient of prostate and bone metasis.his PSA lying
>> between 0.33-4001 in last 5 years..
[quoted text clipped - 60 lines]
>
> Steve J

Reply to this Message

Steve Kramer - 05 Apr 2007 17:25 GMT

> Steve......I ran a Whois search and this man is in or near New Delhi,
> India. He has posted before. I was trying to remember his nationality,
[quoted text clipped - 3 lines]
> Steve Kramer......do you remember this fellow?? And I take it that his
> PSA went from 0.33 UP TO 4001 in 5 years. That rang a bell too.

I do remember him (her?). However the PSA history is sketchy. He was dx'ed
at 2,705 in 2002. I understood the PSA went to 4,000 in 2005, only three
years later.

Clearly, there is a language problem.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years
EBRT 05-07/2002 @ 47
PSA .34 .22 .15 .21 .32 PSAD .056 years
Lupron 07/03 (1 mo) 8/03 and every 4 months there after
PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years
Casodex added daily 07/06
PSA <0.04, <0.05
Non Illegitimi Carborundum

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Alan Meyer - 05 Apr 2007 04:58 GMT

>> my father is patient of prostate and bone metasis.his PSA lying
>> between 0.33-4001 in last 5 years..
> ...

Steve,

That was a very useful and well researched posting you
provided. I admire your efforts to research the facts
before you write anything.

I have seen another posting made by zasu not to this
group. I've gotten the impression that his father's doctors
have done an excellent job, keeping him alive for some
years, but the poor man's time is running out.

zazu,

I am very sorry about your father's condition. I hope that
he can get strong pain medication to help him through the
time to come.

Best wishes to you and your father.

Alan

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Steve Kramer - 05 Apr 2007 17:26 GMT

> but the poor man's time is running out.
>
[quoted text clipped - 3 lines]
> he can get strong pain medication to help him through the
> time to come.

Alas, I think that says it all.... and succinctly.

Reply to this Message

Steve Kramer - 05 Apr 2007 17:21 GMT

>> my father is patient of prostate and bone metasis.his PSA lying
>> between 0.33-4001 in last 5 years..
[quoted text clipped - 9 lines]
>
> What is his treatment history? Surgery? Radiation (what type)? Other?

Zazu's father was 59 when dx'd in 2002 with a 2,704 PSA. They performed an
orchectomy and "Tab Flutamide TDS". The PSA went down, but in 2005 back up
to 4000. Then they went with "Tab Ketcanasole" and the PSA went down to 64
in 9 months. Then, they added "Tab Honvan" and the PSA went down to 2.9. I
don't all the dates, but Zazu's most recent post said his PSA was back up to
187. That was a couple of months ago, as I recall.

They are in India.

Signature

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