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Medical Forum / Diseases and Disorders / Prostate Cancer / April 2007

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psa

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jim west - 04 Apr 2007 16:36 GMT
How likely is to have a stable or declining PSA total after one year if
cancer is present?
fred - 04 Apr 2007 19:56 GMT
> How likely is to have a stable or declining PSA total after one year if
> cancer is present?

One year after what? Surgery? Radiation? Brachy? Seems to me that the
answers may be different.

I think that after surgery, it's not very unusual to have stable PSAs
for several years and then to see PSA rise indicating a possible
recurrence. Someone on this NG indicated that for those who had a
recurrence post-surgery, average time from surgery to first PSA rise
was about 3 years.

Then we get back into the old debate about standard versus
supersensitive tests. Standard tests (lowest score <0.1) can seem to
produce stable scores (a series of <0.1s) while supersensitive tests
would show successive rises below 0.1. But there is controversy if
supersensitive tests are really accurate at low readings, and even if
they are, whether a score of <0.1 has any real clinical significance.

And then the term "if cancer is present." If you have a later
recurrence after a series of stable readings, doesn't that really
imply that the cancer was present (but undetectible) all the time?

I think the bottom line is this; if you have declining/stable PSA
after treatment, enjoy it!! When you think about it, all of us
(whether a member of our club or not) are one test away from a health
problem.

Fred
jim west - 04 Apr 2007 20:05 GMT
Fred thanks for the reply.

>>How likely is to have a stable or declining PSA total after one year if
>>cancer is present?
[quoted text clipped - 25 lines]
>
> Fred
 
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