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Medical Forum / Diseases and Disorders / Prostate Cancer / April 2007X-Ray question?
Anyone know how the heck they tell the difference between mets and arthitis? Seems like the 2 are always getting mistaken for each other when first x-rayed? My spine shows severe artritis, as most of us at our age do, but of course I'm always concerned of the worst case scenario. I wonder if we can have mets, that doesn't show as an elevated PSA?  SignatureJK Sinrod www.SinrodStudios.com www.MyConeyIslandMemories.com > Anyone know how the heck they tell the difference between mets and > arthitis? Seems like the 2 are always getting mistaken for each other when > first x-rayed? My spine shows severe artritis, as most of us at our age do, > but of course I'm always concerned of the worst case scenario. I wonder if > we can have mets, that doesn't show as an elevated PSA? If I understand correctly, it is possible for a metastatic prostate cancer not to produce any PSA, but it is rather unlikely. > Anyone know how the heck they tell the difference between mets and > arthitis? Seems like the 2 are always getting mistaken for each other when > first x-rayed? My spine shows severe artritis, as most of us at our age > do, but of course I'm always concerned of the worst case scenario. I > wonder if we can have mets, that doesn't show as an elevated PSA? Richbro has mets and his PSA, when last reported, was 0.9. That caught MY attention. SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA <.1 <.1 <.1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05, 2/06, 6/06 PSA .07 .05 .06 .09 .08 .132 .145 Casodex added daily 07/06 PSA <0.04, <0.05 Non Illegitimi Carborundum > Richbro has mets and his PSA, when last reported, was 0.9. That caught MY > attention. Quick update, my latest PSA is 1.7 and, yes, I have had at least two (2) spots diagnosed as mets in my upper legs (1 in each leg). The size was ~1 centimeter and we're watching. I did start zometa. By the way, I'm also the lucky one where my lymph nodes were positive (found after syrgery) with a going-in PSA of 4.8. Spent ~18 months with HT working, then PSA rise This took place over 3 years elasped time from detection to bone mets, so I guess a quick summary statement is that it did have 3 years to brew even though I did control the PSA with the traditional controls. There was a 5 month stint of taxotere in there too after HT failed. I also have other spots that they haven't been abe to confirm - one in my hip area that they believe is arthritis. Rich > Anyone know how the heck they tell the difference between mets and > arthitis? Seems like the 2 are always getting mistaken for each other when > first x-rayed? My spine shows severe artritis, as most of us at our age do, > but of course I'm always concerned of the worst case scenario. I wonder if > we can have mets, that doesn't show as an elevated PSA? I had CT scans at 2 institutions in 2002. Both times they were unable to "read" the results because of damage from ankylosing spondylitis (since ca. 1974, diagnosed in 1976), and they had to resort to x-rays to differentiate cancer from A.S. > Anyone know how the heck they tell the difference between mets and > arthitis? Seems like the 2 are always getting mistaken for each other when [quoted text clipped - 4 lines] > -- > JK Sinrodwww.SinrodStudios.comwww.MyConeyIslandMemories.com I am a diagnostic radiologist and hopefully can answer your question. I assume you are referring to the frequent confusion on bone scans. The compound used in bone scans goes anywhere in the skeleton where there is active bone formation or destruction. It is completely non specific as to what is causing the activity and will go to mets, arthritis, healing fractures, etc. The way to tell the difference is by the distribution (if the activity is centered on the joints, it's likely arthritis) and the plain xray appearance. In my practice, we review every bone scan before letting the patient go in order to decide if any extra xrays are needed for exactly the reason you cite. Hope this helps. CPW > I am a diagnostic radiologist and hopefully can answer your question. Good to see you poke your head in again, Paul. How are YOU doing? Still undetectable? SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA <.1 <.1 <.1 .27 .37 .75 PSAD 0.19 years EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 PSAD .056 years Lupron 07/03 (1 mo) 8/03 and every 4 months there after PSA .07 .05 .06 .09 .08 .132 .145 PSAD 1.4 years Casodex added daily 07/06 PSA <0.04, <0.05 Non Illegitimi Carborundum > > I am a diagnostic radiologist and hopefully can answer your question. > [quoted text clipped - 14 lines] > PSA <0.04, <0.05 > Non Illegitimi Carborundum I'm doing well, Steve. Still undetectable. Sounds like you are doing well too. I still lurk regularly but only contribute when a radiology question comes up, as a rule. Paul > I'm doing well, Steve. Still undetectable. > Sounds like you are doing well too. > I still lurk regularly but only contribute when a radiology question > comes up, as a rule. Sounds great, Paul! Lurk on! |
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