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Medical Forum / Diseases and Disorders / Prostate Cancer / March 2007

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Weight Gain

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From Bob - 20 Mar 2007 01:44 GMT
Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
15 pounds, with no change in diet, over my previous eating habits.
Despite workng out on the treadmill each morning, i am unable to loose
this weight. Seems that my metabolism was adversley effected by the
lupron.
Heather - 20 Mar 2007 03:24 GMT
> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have
> gained
> 15 pounds, with no change in diet, over my previous eating habits.
> Despite workng out on the treadmill each morning, i am unable to loose
> this weight. Seems that my metabolism was adversley effected by the
> lupron.

Unfortunately, that is a totally normal side effect.  Ron gained 25 lbs.
at about 9 months.  I think a fair bit of it is water retention.  His
was around the waist and he did slim down a bit after quitting
HT.....but is still up about 15 lbs.

Rather like quitting smoking which I did 13 months ago.  I have gained
about 10+ lbs in the same area.  Not impressed with that!!  But I am now
addicted to Smarties, so that is the next thing to cut out.  (G)

Heather
rosbif - 20 Mar 2007 09:56 GMT
> But I am now
>addicted to Smarties, so that is the next thing to cut out.  (G)

Why not just stick to the 'Smarties Diet' and cut out everything else?
Heather - 20 Mar 2007 18:06 GMT
>> But I am now
>>addicted to Smarties, so that is the next thing to cut out.  (G)
>
> Why not just stick to the 'Smarties Diet' and cut out everything else?

ROFL!!  I wish!!  I have the most incredible inability to lose weight.
Low metabolism, perhaps.  For example, after the jaw surgery, I couldn't
eat much for weeks and still only lost one pound.  P*ss me off, I will
tell you.

Heather
Shirley ann - 21 Mar 2007 11:49 GMT
My Hubby put on 20 pounds after the HT shot.

The doctors  do not seem to worry about this.
His MD says he was obese before HT.

shirleyann
I.P. Freely - 21 Mar 2007 17:21 GMT
> My Hubby put on 20 pounds after the HT shot.
>
> The doctors  do not seem to worry about this.

They're not the ones threatened by its ill effects.

> His MD says he was obese before HT.

Yet another reason to fight it, as its effects are cumulative. It's
going to be even tougher on ADT (HT). But it's still not the threat that
his PC poses, so you're ahead of the game.

I.P.
I.P. Freely - 20 Mar 2007 05:39 GMT
> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
> 15 pounds, with no change in diet, over my previous eating habits.
> Despite workng out on the treadmill each morning, i am unable to loose
> this weight. Seems that my metabolism was adversley effected by the
> lupron.

Standard SE. Many men gain much more. Exercise!

I.P.
Steve Kramer - 20 Mar 2007 09:41 GMT
>> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
>> 15 pounds, with no change in diet, over my previous eating habits.
>> Despite workng out on the treadmill each morning, i am unable to loose
>> this weight. Seems that my metabolism was adversley effected by the
>> lupron.

> Standard SE. Many men gain much more. Exercise!

That's a pretty simplistic reply.  Unless of course your research shows that
as a legitimate response and Bob has informed us that he doesn't already
exercise.

However, it is my current intention to step up the walking and intermingle a
weight lifting program through the Spring and Summer and see if it helps
with the extra layer of fat.
I.P. Freely - 20 Mar 2007 17:45 GMT
>>> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
>>> 15 pounds, with no change in diet, over my previous eating habits.
[quoted text clipped - 7 lines]
> as a legitimate response and Bob has informed us that he doesn't already
> exercise.

Well, the only right way to lose weight involves exercise, whether or
not it includes calorie intake reduction, and exercise also boosts
energy, lack of which is yet another ADT SE. Not to mention that as our
cells die off and are replaced (pretty much our whole body replaces
itself about every 90 days), new research shows the new cells decide for
themselves whether to be couch potatoes or action figures based on the
environment they're born into. It also boosts our immune systems if not
done at marathon levels, and most regular moderate exercisers tend to
eat less. So far, that's win, win. win, win, and win. If the sneaker
fits . . .

Now, about that treadmill . . . as with any other form of exercise, it
can be done at any level from one to ten in intensity and duration. But
I noticed immediately that at a given heart rate (which determines our
perceived level of effort), I burn calories twice as fast on an
elliptical machine I do on a  treadmill, *according to their displays*,
which may mean little since they're different brands (both high-end,
very expensive professional gym machines). BUT maybe the difference is
real because a) I, not a motor, am powering the elliptical, b) I'm
pumping hard on the elliptical's handles rather than just resting my
hands there, and c) I'm not bouncing up and down on the elliptical like
most people do, so I'm using big leg muscles rather than gravity and
momentum to spin the machine.

> However, it is my current intention to step up the walking and intermingle a
> weight lifting program through the Spring and Summer and see if it helps
> with the extra layer of fat.

It should, as muscle burns calories at rest. Walking and running can be
good cardiovascular exercise, but no one ever accused them of building
muscle.

I.P.
Steve Kramer - 20 Mar 2007 20:51 GMT
> Well, the only right way to lose weight involves exercise, whether or not
> it includes calorie intake reduction, and exercise also boosts energy,
> lack of which is yet another ADT SE.

You are correct in that if weight loss is possible, or fat loss, or cell
loss, that exercise and reduced caloric intake is the answer.  Like putting
gas in a car.  If the car has an inflatable gas tank and you just drive it
to the gas station and back, the tank will grow.  But if you drive it
hundreds of miles, the tank will stay small.

However, there may be another issue here that you are missing.  What if
there is a divider in the tank?  The gas that is on the other side of the
divider will never leave the tank unless extraordinary measures are taken to
suck it out.  Or, like the reserve tank on a motorcycle requiring another
avenue of escape.

The man who was in the best physical and mental shape of any other man I
know was a 7th Degree Black Belt (back when that meant something).  He was
also an outstanding swimmer and would take swimming awards nationally until
he was in his 40s, maybe 50s.  Because of his swimming, he always had a
layer of fat that he never lost.  Something to do with the body insulating
itself from the constant lower-degree environment he spent every day in.

I think this added fat is like that.  And, I don't know if ordinary measures
is going to work on it.  Or on Bob's.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  <.1  <.1  <.1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06, 6/06
PSA  .07 .05 .06 .09 .08 .132 .145
Casodex added daily 07/06
PSA <0.04, <0.05
Non Illegitimi Carborundum

I.P. Freely - 20 Mar 2007 22:17 GMT
>  Because of his swimming, he always had a
> layer of fat that he never lost.  Something to do with the body insulating
> itself from the constant lower-degree environment he spent every day in.
>
> I think this added fat is like that.  And, I don't know if ordinary measures
> is going to work on it.  Or on Bob's.

You're right in that swimmers maintain some body fat for insulation;
cold water and air exacerbate that. The body allocates our weight's
distribution and form according to such factors as genetics, activity,
environemnt, etc. Muscle and fat don't transform from one to the other,
but they certainly swap off as those factors change. But while ADT may
affect our metabolism, motivation, and maybe even our "oomph" (I've
never encountered any explanation of ADT's weight gain mechanism), it
can't change the laws of thermodynamics. If we burn more calories than
we consume, we lose weight, and as of yet no one's found a way around
that, according to the many university, hospital, and private,
commercial, and government agency websites and newsletters I follow.
Until they change their tune, I have no reason to change mine.

I.P.
Steve Kramer - 20 Mar 2007 09:36 GMT
> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
> 15 pounds, with no change in diet, over my previous eating habits.
> Despite workng out on the treadmill each morning, i am unable to loose
> this weight. Seems that my metabolism was adversley effected by the
> lupron.

Apparently, a common SE.  I gained 15 on Lupron.  Then, I gained 15 when I
started taking Casodex, plus a layer of fat that makes it look like my
breast, hands and feet are swollen.

ADT is no fun, that's for sure.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  <.1  <.1  <.1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06, 6/06
PSA  .07 .05 .06 .09 .08 .132 .145
Casodex added daily 07/06
PSA <0.04, <0.05
Non Illegitimi Carborundum

Heather - 20 Mar 2007 18:09 GMT
>> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have
>> gained
[quoted text clipped - 9 lines]
>
> ADT is no fun, that's for sure.

Ron had the swollen hands and feet.....so it must be the Casodex which
was the culprit with that......not the Zoladex.

He could do with a *training bra* as well.  In your case, it would be a
"Dolly Parton bra"......bwa ha ha!!

XX  Figgs
kh - 20 Mar 2007 11:35 GMT
> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
> 15 pounds, with no change in diet, over my previous eating habits.
> Despite workng out on the treadmill each morning, i am unable to loose
> this weight. Seems that my metabolism was adversley effected by the
> lupron.

Might be the "hidden exercise".   When I was on Lupron, I was tired
all the time and sleeping more.  I definitely felt lethargic; it
seemed like too much trouble to take out the trash, mow the lawn,
etc.

Add up all the "missing" trips to the basement, the "I'll do it later"
choices, and the "I don't feel like re-arranging my books, I'll just
watch TV".

The treadmill is good only because you can measure it.  20 minutes.
OK, I'm exercising.

If the Lupron takes away the "I think I'll go out back and trim my
hedges" as well as "I'll jack up my car and check the brakes",  you're
getting much less "exercise".

Ever notice that skinny people are always moving, fidgeting.  The
Lupron steals that from us.

-kh swiveling your head to check out the blond in the convertible,
that's 50 calories.
Alan Meyer - 20 Mar 2007 15:04 GMT
> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
> 15 pounds, with no change in diet, over my previous eating habits.
> Despite workng out on the treadmill each morning, i am unable to loose
> this weight. Seems that my metabolism was adversley effected by the
> lupron.

I was on Lupron for 4 months and didn't gain any weight.
However I was also receiving radiation treatment for part
of that time.  Maybe that works the other way with respect
to weight gain.

I did exercise as hard as I could, but my running was down
to 25% of what it had been before Lupron and radiation.  I
had the feeling that if I ran any further or harder I would
collapse.

   Alan
WhiteSoxFan - 20 Mar 2007 15:34 GMT
My whole life I was blessed with a hyperactive metabolism. I could eat
anything without regard to moderation. Now in my 50s the weight
steadily rose. When I began Lupron and Casodex 10 months ago I quickly
gained 10 lbs in about 5 mos. I stopped the HT in January and my
weight, for the most part held. I just can't get to the point of that
1500 or less caloric day which I think along with a daily 30 minute
power walk is the ticket to getting me back into the low 170s or my
target of upper 160s. Actually, now that the weather is warmer, it
should be easier to get out more. Since my entry into this club about
a year and a half ago, I've greatly improved my diet and reduced the
amount of food I consume. I attribute that to why I 'only' gained 10
lbs. The more troubling SE was the gain in glucose level. And as long
as were on the subject of SEs, I've lost a lot of hair all over my
body. My former hairy legs now have two vertical patches running down
my shins. Looks very wierd.

SIU fan. Go Saluki's
I.P. Freely - 20 Mar 2007 17:57 GMT
> I just can't get to the point of that
> 1500 or less caloric day which I think along with a daily 30 minute
> power walk is the ticket

Watch the calorie restriction. Too low, and your body goes into hoarding
mode for self-preservation, cutting our metabolism way back, tending to
offset the power walk. Hoarding starts at about 1200 calories for women
if I recall correctly; it may be 1500 for guys. And weight lost by
dieting without strength-building exercise is largely muscle, which
further cuts back our resting metabolism.

I.P.
Bob C. - 20 Mar 2007 16:55 GMT
> Since receiving Lupron, 30 mg in 3/06, and 30 mg in 7/06, i have gained
> 15 pounds, with no change in diet, over my previous eating habits.
> Despite workng out on the treadmill each morning, i am unable to loose
> this weight. Seems that my metabolism was adversley effected by the
> lupron.

Hi Bob, another Bob here, Bob C,  in the boat along with you. After
being on Lupron for over a year, I decided to really go great guns and
get some of that weight off. I used a computer program to carefully
track calories, and many other nutritional facts, and the program was
supposed to tell me what to do to meet my goal of a one pound loss per
week. Then I had to change it to one pound per month as a goal. The
program, after three months, told me that something was wrong and I did
not have an attainable goal as I was down to so low a calorie intake
without results. It was weird, and I was really glad to quit the program.

Somewhere in my second or third year of Lupron, a different doctor
finally told me to not even worry about the weight thing, but to do an
additional half hour on the treadmill every day. Not a half hour, an
hour, split it up however if need be. And every day, not three or four
days a week, every day. He was basically saying to do what you can to
minimize the effects of the weight gain and not fret over the weight
itself. Sure, do what you can to minimize additional gain, but that is
not a battle you will win. Same with taking it off once you got it, much
of it has gone on in places where a guy normally does not have fat
layers, and it's not likely to come off.

I have been "off" Lupron this past year, a vacation so to speak, and
also retired during that time and am vastly more active than I had been.
 The weight immediately dropped about 9 pounds over two months, and
then came back on almost as fast. I feel a lot better due to the
increased activity level, but do not expect to ever fit back into my
clothes of last year, much less earlier years. There has been weight
gain every year on Lupron, and when I go back on it and Casodex next
month I expect to again be dismayed to see a slow creep upward. That
first year was by far the worst for weight gain  though, if that is any
consolation.

Perhaps if a person could stay off Lupron long enough relative to the
amount of time on it,  it might be possible to get rid of some of the
new weight, I don't know. None of this is medical advise, just my own
experience. Good luck to you,
 
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