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Medical Forum / Diseases and Disorders / Prostate Cancer / January 2007

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Prostate nodules in my lungs

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R.W. L. - 26 Jan 2007 05:52 GMT
Two years ago last July, I had a Turps procedure following which it was
discovered that I had prostate cancer with Gleason score of 8.  I opted
to have external beam radiation.  Bone scans and CT scans indicated no
metastasis, although the radiation oncologist said there was something
on a rib.  (He did not say it was something to be concerned about.  I
took a Lupron shot a few weeks prior to the 29 radiation sessions.  My
psa was about 0.7 after the treatments.  It rose a little three months
later.   Last Feb. it was 2.7 and three months later it was 6.9.  My
urologist had bone scans and CT scans of abdomen and pelvis about this
time that did not show any thing, but the radilogist said he saw
something in lower part of chest.  He advised a CT Scan of chest.  That
revealed many nodules in my lungs.   Needle biopsy of one treated with
psa stain revealed positive results for prostate cancer of the lungs.  
I began lupron shots immediately and my psa dropped to 0.1 for the last
six months on two consecutive times it was measured.  The Oncologist
ordered x-rays that indicated the nodules were "resolving".  To confirm
this he had another CT Scan of my chest.  He said he was very pleased
and he turned the case over to the urologist.  (He was planning a move
to another city...and this may have had a bearing).  The urologist has
started used Eligard shots instead of Lupron.  I have been drinking
Pomegranite Juice on my own initiative after reading a report from
Urology conference in summer of 2005.

I would appreciate your comments and suggestions.   Thanks,  Ralph
Steve Jordan - 26 Jan 2007 07:03 GMT
On January 25, Ralph wrote, in pertinent part:

> Needle biopsy of one treated with
> psa stain revealed positive results for prostate cancer of the lungs.  
[quoted text clipped - 7 lines]
> Pomegranite Juice on my own initiative after reading a report from
> Urology conference in summer of 2005.

A urologist is trained as a surgeon.

This case is beyond the capability of a surgeon.

I recommend immediate consultation with a cancer specialist, a medical
oncologist. Preferably one who is well-trained in tx of PCa.

Eligard is chemically the same as Lupron; both are leuprolide acetate. I
wonder whether the uro had an economic motive for the change.

The referenced study on pomegranate juice involved only 48 men, all of
whom had been treated for PCa and who were not as far advanced as Ralph.
Other studies (2006) appear to involve mice.

Two more recommendations:

1. The authoritative website of the Prostate Cancer Research Institute
(PCRI) at:

http://prostate-cancer.org/index.html

.....and see the section "Advanced PC."

2. Obtain and read the handbook "Living with Advanced Prostate Cancer."
It is available free from the Institute for Continuing Healthcare
Education at www.iche.edu/advancedpca

Has anyone thought to order a check on bone mineral density (BMD)? I'd
bet not. Loss of BMD (aka osteoporosis) is an inevitable result of
androgen deprivation therapy (ADT), which is what the leuprolide acetate
is. It is treatable/preventable. All too many medics are ignorant about it.

There may be other side effects (SEs) of the ADT. One can learn about
them and their txs on the PCRI site. See: Androgen Deprivation Syndrome.

Study, Learn, Take Charge!

Regards,

Steve J

"Empowerment: taking responsibility for and authority over one's own
outcomes based on education and knowledge of the consequences  and
contingencies involved in one's own decisions. This focus provides the
uplifting energy that can sustain in the face of crisis."
--Donna Pogliano, co-author of _A Primer on Prostate Cancer_, subtitled
"The Empowered Patient's Guide."
MAS - 26 Jan 2007 07:11 GMT
Sorry to hear Ralph. My only suggestion is to consider finding a Medical
Oncologist who specializes in Prostate Cancer. Yes a Radiation Oncologost
and a Urologist can treat Advanced Prostate Cancer, but when I asked, all
said that if they were in my shoes that they would seek out a MO
specializing in PCa. They also said that to be sure that the MO specializes
in PCa as he would have a better idea on how to approach the situation.

BTW, I prefer Eligard over Lupron.

Good Luck,

Gourd dancer

Does not hurt to ask.
> Two years ago last July, I had a Turps procedure following which it was
> discovered that I had prostate cancer with Gleason score of 8.  I opted
[quoted text clipped - 20 lines]
>
> I would appreciate your comments and suggestions.   Thanks,  Ralph
R.W. L. - 26 Jan 2007 23:45 GMT
Thanks for all of your support and good information.  I will be checking
out the references, etc.

Blessings,
~Ralph
kh - 26 Jan 2007 17:14 GMT
> ...  That
> revealed many nodules in my lungs.   Needle biopsy of one treated with
> psa stain revealed positive results for prostate cancer of the lungs.

This is interesting.  My PSA is rising and my docs have been tracking
"Scattered ill-defined nodular densities of sub-centimeter size .. with
absent metabolic activity, as expected for their size."  for the last 6
months.

This was first picked up in a radioactive heart scan, confirmed by two
enhanced CAT-scans and MRI, no metabolic activity/hot spots on a
Prostascint, PET-scan, or 2 bone scans.

So what is it?

Something is going on but what?    Anyone have anything like this?

-kh
Richbro - 27 Jan 2007 03:04 GMT
kh et. all,

I have scattered ill-defined nodular densities in my lungs (no
confirmation they are anything at this point). They are repeating my CT
scan every 6 months to track. I also have a few very small (around 1
centimeter) bone METS, also tracking. So far, the size hasn't been
enough to treat, but I'm heading for another treatment zone as my PSA
is rising after 5 months of taxotere last year. I had positive Lymph
nodes and am now hrpc, so the battle will be on-going...

I agree w/Steve; it's amazing how the different medicines have
advanced. My onc told me, a few years ago, you wouldn't be around for a
year or two, now they're extending life (with reasonable QOL) quite a
few years. byw, my onc has terrible bedside manners, but he knows his
stuff.

Keep on trucking, Rich

> > ...  That
> > revealed many nodules in my lungs.   Needle biopsy of one treated with
[quoted text clipped - 12 lines]
>
> -kh
Steve Kramer - 26 Jan 2007 20:34 GMT
> Two years ago last July, I had a Turps procedure following which it was
> discovered that I had prostate cancer with Gleason score of 8.  I opted
[quoted text clipped - 20 lines]
>
> I would appreciate your comments and suggestions.   Thanks,  Ralph

Welcome, Ralph, to the newsgroup.

The only comment I would have is, ain't medicine great!  With a G8 and lung
mets, it has not been all that long ago that you would have been near-term
terminal.

I'm reading good things about Pomegranate Juice, but I suspect it was the
Lupron that knocked your PSA back.  And, when that starts to wander up
again, they can add Casodex and knock it back down again. (which is where I
am).  Looks like you have a few years to carouse and cause mayhem.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06, 6/06
PSA  .07 .05 .06 .09 .08 .132 .145
Casodex added daily 07/06
PSA <0.04
Non Illegitimi Carborundum

SurvivingCancer@gmail.com - 27 Jan 2007 03:07 GMT
I know from a personal experience that an FNA diagnosis of metastatic
prostate adenocarcinoma is a very tricky diagnosis and requires an
experienced pathologist. It could possibly require immunostains on the
cell block of your FNA. I would sincerely advise you to obtain a second
opinion on you FNA slides. It changed my own life. I recommend Confirm
Path company. They are dedicated for second opinions. check out their
website. they will charge you for the second opinion service but hey it
did change my life and you can even ask their pathologist physician a
question for free. their website is confirmpath.com. Good Luck

> Two years ago last July, I had a Turps procedure following which it was
> discovered that I had prostate cancer with Gleason score of 8.  I opted
[quoted text clipped - 20 lines]
>
> I would appreciate your comments and suggestions.   Thanks,  Ralph
 
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