Medical Forum / Diseases and Disorders / Prostate Cancer / January 2007
Do you have daughters?
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Mary Fisher - 03 Jan 2007 10:10 GMT Reported on BBC Radio 4 news just now, an Israeli study reports that men who have daughters rather than sons have a greater chance of developing prostate cancer.
I can't remember the number of men in the study but apparently if a man has three daughters and no sons then he is 60% more likely to develop prostate cancer than a man with no daughters.
<shrug>
For the record, we have three sons and two daughters, all conceived and born during our twenties. Spouse has had no other children (or wives or lovers - we're very boring), his prostate cancer was diagnosed in 2006.
Mary
Beverley - 03 Jan 2007 11:02 GMT We have two daughters (no sons). We're pretty boring, too! Bev
> Reported on BBC Radio 4 news just now, an Israeli study reports that men > who have daughters rather than sons have a greater chance of developing [quoted text clipped - 11 lines] > > Mary c palmer - 03 Jan 2007 11:26 GMT hi mary - here's the article.....
by the way. i had four sons. three living.. one died at birth...
~ curtis
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Daughters linked to prostate risk The gender of a man's children may be linked to his cancer risk Men who father daughters, not sons, may be at a greater risk of developing prostate cancer, researchers have said.
The Israeli team found men with three daughters and no sons were up to 60% more likely to develop prostate cancer. But the Journal of the National Cancer Institute study suggests the cause may be the male "Y" sex chromosome, not the act of having either a son or daughter.
UK experts said a common genetic cause may affect both cancer risk and the chance a man will father girls.
Prostate cancer is the most common male cancer, with more than 30,000 new cases in the UK in 2003.
It affects the prostate gland, which is found near the bladder in men, and produces one component of semen.
The Israeli research looked at more than 38,000 men, and compared the families of the 712 diagnosed with prostate cancer with those of the other men.
Overall, compared with men who had at least one son, those with only daughters were 40% more likely to develop prostate cancer.
The risk increased when a man had three or more daughters and no sons.
The researchers looked for alternative explanations for the apparent difference. Since prostate problems are often only detected when a man attends for routine health screening, they suggested that it was possible that having a predominantly female family might encourage a man to be more health-conscious.
No-one should rush off with the idea that girls give their fathers prostate cancer
Another possibility was that men having daughter after daughter might go to the doctor to find out if there was any problem stopping them from fathering a son.
Poor conception
However, there was no evidence to support these explanations, and the researchers suggested that a genetic cause could be contributing to both the birth of daughters and the risk of cancer. Men supply one sex chromosome in their sperm - this can be either a Y, producing a male embryo, or an X, producing a female embryo.
Faults on the man's Y chromosome might not only affect the likelihood of conception or development of male offspring, but also lead to cancer development, it was suggested.
The Prostate Cancer Charity head of policy and research Chris Hiley said: "This is an interesting study - it certainly attracts the attention, but it doesn't yet translate into useful advice for men until other complex genetic studies are done. "Further research to confirm these findings in men from other parts of the world is needed.
"We also need to uncover exactly what it is about the Y chromosome, which only men have, that might make men who are diagnosed with prostate cancer also more likely to have fathered girls rather than boys.
"In the meantime no-one should rush off with the idea that girls give their fathers prostate cancer."
knowledge is power - growing old is mandatory - growing wise is optional "Many more men die with prostate cancer than of it. Growing old is invariably fatal. Prostate cancer is only sometimes so." http://community.webtv.net/PALMER_ENT/doc
Mary Fisher - 03 Jan 2007 12:00 GMT > Daughters linked to prostate risk > [quoted text clipped - 10 lines] > UK experts said a common genetic cause may affect both cancer risk and > the chance a man will father girls. <snip stuff we know!>...
> The Israeli research looked at more than 38,000 men, and compared the > families of the 712 diagnosed with prostate cancer with those of the [quoted text clipped - 44 lines] > "In the meantime no-one should rush off with the idea that girls give > their fathers prostate cancer." LOL!
Thanks, Curtis. I knew someone would have more.
I'm also sorry about the loss of your son, it's never happened to me but I think it must be tragic.
Mary
callalily - 03 Jan 2007 15:10 GMT Hello--
> The gender of a man's children may be linked to his cancer risk > Men who father daughters, not sons, may be at a greater risk of > developing prostate cancer, researchers have said. Well, these men are lucky in one way: they have a much better of being taken care of when they get sick. In my family my 3 brothers do a disappearing act when it comes to "eldercare".
I read somewhere a few days ago that if you want to ensure that you are well taken care of in your old age you should have 7 daughters. At least.
LFC
PS: I just got a msg from google saying my email isn't working properly. That's why my msg on cross-posting posted 3 times.
Mary Fisher - 03 Jan 2007 11:26 GMT > We have two daughters (no sons). We're pretty boring, too! It's the simplest way to live :-) There are enough complications without adding to them!
Mary
> Bev > [quoted text clipped - 17 lines] >> >> Mary Leonard Evens - 03 Jan 2007 14:27 GMT > Reported on BBC Radio 4 news just now, an Israeli study reports that men > who have daughters rather than sons have a greater chance of developing [quoted text clipped - 9 lines] > during our twenties. Spouse has had no other children (or wives or lovers - > we're very boring), his prostate cancer was diagnosed in 2006. I have two daughters and one son.
> Mary chasjac - 03 Jan 2007 15:07 GMT My wife and I have two teenage sons, no daughters.
--charlie
Mary Fisher - 03 Jan 2007 16:20 GMT > My wife and I have two teenage sons, no daughters. It WILL get better, honestly :-)
Mary
> --charlie Bill - 03 Jan 2007 15:16 GMT "if a man has three daughters and no sons then he is 60% more likely to develop prostate cancer than a man with no daughters."
Yea, but after living w/ 4 women, his life is shortened already! :-)
FWIW my brother has 2 daughters, no sons, and PCa. Bill Denton RP 2/12/02 PSA 1.10 Memphis
Richbro - 03 Jan 2007 20:00 GMT I'm surrounded by females. Wife (of course), daughter #1, daughter #2, and daughter #3. The daughters #2 and #3 have daughters, so I have granddaughters #4 and #5. Fortunately, all daughters have moved out, so we only have permanent residency when there are crisis and turmoil which happens about once a month. My son moved to New Mexico and we rarely hear from him.
I'm having a little fun here, but believe me - all my daughters and granddaughters and my wife are the loves of my life - wouldn't trade them in for anything.
Rich RP 12/18/2003 LN positive HRPC 11/2005 Taxotere 15 treatments in 2006 Current PSA 0.9 Bone Mets beginning to show in hip
Mary Fisher - 04 Jan 2007 10:17 GMT > I'm surrounded by females. Wife (of course), daughter #1, daughter #2, > and daughter #3. The daughters #2 and #3 have daughters, so I have > granddaughters #4 and #5. Fortunately, all daughters have moved out, so > we only have permanent residency when there are crisis and turmoil > which happens about once a month.
:-)
> I'm having a little fun here, but believe me - all my daughters and > granddaughters and my wife are the loves of my life - wouldn't trade > them in for anything. Good for you! I must admit that I found rearing daughters easier than the sons. The boys wore me out, always hurling themselves about, their voices were more piercing and they built things only to knock them down again!
But when they grow up they suddenly become reasonable adults.
When they have their own children they suddenly become sensible and, somehow, remember being perfectly behaved children ...
Mary
> Rich > RP 12/18/2003 [quoted text clipped - 3 lines] > Current PSA 0.9 > Bone Mets beginning to show in hip NICK - 03 Jan 2007 18:55 GMT > For the record, we have three sons and two daughters, all conceived and born > during our twenties. Four sons (no daughters) conceived and born between age 24 and 34.
Joe Price - 03 Jan 2007 21:45 GMT Combining the two informal surveys - I have two daughters and also had a vasectomy. For two points, guess which I had first - the daughters or the vasectomy ; )
>> For the record, we have three sons and two daughters, all conceived and >> born >> during our twenties. > > Four sons (no daughters) conceived and born between age 24 and 34. Richbro - 03 Jan 2007 21:56 GMT But, how many Toyotas drove by your house on the day of your vasectomy?
Rich
> Combining the two informal surveys - I have two daughters and also had a > vasectomy. For two points, guess which I had first - the daughters or the [quoted text clipped - 5 lines] > > > > Four sons (no daughters) conceived and born between age 24 and 34. NICK - 04 Jan 2007 05:55 GMT > ...apparently if a man has three daughters and no sons then he is 60% > more likely to develop prostate cancer than a man with no daughters. What if he has 3 sons and 2 daughters -- all at once? <g>
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