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Medical Forum / Diseases and Disorders / Prostate Cancer / December 2006

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Update--PSA rise situation

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MZB - 07 Dec 2006 05:29 GMT
Well, I previously posted the item below and got a lot of good answers at
least confirming that I should be concerned.

However, I did follow up and spoke with my regular physician who I regard
highly, as well as another physician who I respect (his specialty if
internal medicine and gerontology). THey both pretty much supported what my
urologist (who is from Univ. of Mich Hospital) said. Given my BPH, this rise
is not unusual. So, we will test again in the Spring and go from there. I'm
still uneasy about all of this, but now THREE doctors have given me the same
advice. I'll keep you all informed anyway!

My urologist doesn't seem too concerned. I am 60 1/2 years old. Here's the
history below of my PSA  scores. Note the increased rise in the recent past.

While he is not concerned, my thoughts are to get another PSA in May or so.
If it is still increasing at this latest rate, then maybe get at least a
Free PSA. At what point is more action in the way of tests needed (and what
tests?)

11/2006   3.1
7/2006 2.67
2-05 2.2
3-04 2.15
2-03 2.0
11-01 2.1
10-00 2
10-99 1.7
10-98 1.6
10-97 1.5
10-96 1.3
6-95 1.2

MB
Claude - 07 Dec 2006 14:37 GMT
How would it hurt to get the free PSA now?  My internist used BPH as the
reason for my PSA rise (However, my numbers were higher than yours---4's and
5's).  I think the free PSA would give you one more bit of data that may put
your mind more at rest or give you a more specific direction.

> Well, I previously posted the item below and got a lot of good answers at
> least confirming that I should be concerned.
[quoted text clipped - 32 lines]
>
> MB
MZB - 07 Dec 2006 21:30 GMT
I think he is suggesting a free-PSA and some other kind of PSA -- but in
about 6 months.

(That may better to help ascertain a trend -- but one has to temper this
against the dangers of waiting too long -- at this point, I guess I'll go
along with the three doctor suggestions)

Mel
> How would it hurt to get the free PSA now?  My internist used BPH as the
> reason for my PSA rise (However, my numbers were higher than yours---4's
[quoted text clipped - 38 lines]
>>
>> MB
Dick Smith - 07 Dec 2006 22:50 GMT
I don't see why they would wait to do a fPSA blood test. I mean it's
simple, and a fPSA can help determine the odds of it being cancer or
not. I would think the fPSA result would be the determining factor to
wait for the biopsy or not.

Just my 2 cents though.
From Bob - 07 Dec 2006 21:37 GMT
I was treated for bph for many years, and took 5mg of proscar daily. On
11/7/05 my psa was 1.40, then on 2/6/06 the psa went to 1.77,
(velocfity change of 0.37 )  both the urologist and my internist were
not concerned, and felt we should wait and retest at a later date.

Because of a family history of pca (brother), i demanded that a biopsy
be done. Result was 3 positive cores out of 12, with a gleason of 7 ( 4
+ 3). I am 69 years old, and had ADT for 8 months (Luperon), and Seeding
(palladium), followed by 25 sessions of IMRT.

I feel that you have nothing to loose by getting a biopsy, and
everything to gain (your life).

Note- Due to the fact that i was on proscar, the psa readings above need
to be doubled to get a realistic value.
ron - 07 Dec 2006 21:57 GMT
A color doppler ultrasound by someone experienced in using this
technique to examine prostates, might be a reasonable, non-invasive
next step.  Of course, if something is seen, a targeted biopsy good be
performed..ron
Alan Meyer - 07 Dec 2006 23:28 GMT
> A color doppler ultrasound by someone experienced in using this
> technique to examine prostates, might be a reasonable, non-invasive
> next step.  Of course, if something is seen, a targeted biopsy good be
> performed..ron

Ron,

Do you know what the merits of color doppler ultrasound are as
compared to biopsy?  Is it being used anywhere as a replacement
for biopsy?  Is it more or less accurate?

I'm asking largely because of the the thread by "Dr. Diaz" with
the subject "Prostate biopsies cab be avoided quite often".  If
you look at Dr. D's website, he makes a ton of outrageous claims
and seems to imply, without coming right out and saying, that
if you get a color ultrasound (he doesn't use the word doppler)
and it comes out clear, you don't need a biopsy.

Do you have any thoughts on that?

Thanks.

   Alan
ron - 08 Dec 2006 00:03 GMT
Hi Alan...I've inserted my thoughts within your text...Best wishes and
good health, ron

> > A color doppler ultrasound by someone experienced in using this
> > technique to examine prostates, might be a reasonable, non-invasive
[quoted text clipped - 5 lines]
> Do you know what the merits of color doppler ultrasound are as
> compared to biopsy?

non-invasive
"sees" the entire prostate, not just areas that can be sampled by
trans-rectal biopsy
much better visualization than standard B&W ultrasound
permits targeted biopsy, if desired

>Is it being used anywhere as a replacement
> for biopsy?

Not that I am aware of

>Is it more or less accurate?

Supposedly it is very accurate when used by an "artist"

> I'm asking largely because of the the thread by "Dr. Diaz" with
> the subject "Prostate biopsies cab be avoided quite often".  If
> you look at Dr. D's website, he makes a ton of outrageous claims
> and seems to imply, without coming right out and saying, that
> if you get a color ultrasound (he doesn't use the word doppler)
> and it comes out clear, you don't need a biopsy.

I don't know, but I've never heard anyone else say that.  I suggested
cdus in this case as a non-invasive, possible, next step - not a final
diagnostic step.  It could be done with or without biopsy.  If it were
me and the cdus was suspicious, or if my PSA continued to rise,  or if
my fPSA was low, I'd get a biopsy

> Do you have any thoughts on that?
>
> Thanks.
>
>     Alan
Alan Meyer - 08 Dec 2006 01:51 GMT
Thanks Ron.

It sounds like Dr. Diaz is an "artist" alright, but perhaps more
of the "con" variety than the "expert" type.

If you haven't done so, I suggest you have a look at his website.

   Alan
Alan Meyer - 07 Dec 2006 23:44 GMT
...
> still uneasy about all of this, but now THREE doctors have given me the same
> advice.
...

What we have here is a classic case.

Patient sees a doctor.
Doctor says, do X.
Patient says, but I want to do Y.
Patient gets a second opinion.  2nd doctor says do X.
Patient gets a third opinion.  3rd doctor says do X.
Patient still wants to do Y.
What should he do?

People on this newsgroup are almost all people who have or
had prostate cancer, and we're hypersensitive to it.

But in this case, you've consulted 3 experts, one a guy you
didn't know, but a professor of the specialty involved, and the
other two guys that you do know and highly respect.

The professor for sure, and all three doctors very possibly,
know more than any of us on this newsgroup do.

On the one hand, it's your life, not the professor's life.  It's
easy for him to say everything's okay.  His life isn't at
stake.

But on the other hand, as you say, you've now got three
professional opinions all going one way and a bunch of
very non-professional opinions that lean the other way.

I think at this point I'd follow the doctors' advice.

Cancer treatment is no piece of cake.  If you do have cancer,
and if it can be treated 6 months from now with just as high
a probability of success as now, then it might very well be
better to wait anyway and enjoy your six months.  Think of
it as watchful waiting - a reasonable option in some cases
even for people that have an actual diagnosis of cancer.

What's that you say, you're not enjoying life because of the
anxiety?  I have a suspicion that if you get a biopsy and
it comes back negative, you won't have any less anxiety.
You'll worry about whether the doc missed the right spots
in the prostate.

Maybe it's time to stop obsessing and think about other
things.

Maybe.

I don't know.  Who am I to say?

    Alan
MZB - 08 Dec 2006 04:42 GMT
Well, I've made an appointment for 4/28 (a little over 4 months from now)
and I'll get the tests at that time.

So, it's a bit shorter than 6 months.

I've consulted 3 doctors and, yes, I am going to go with their opinions (but
follow-up in 4 months instead of 6)

Mel

> ...
>> still uneasy about all of this, but now THREE doctors have given me the
[quoted text clipped - 53 lines]
>
>     Alan
 
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