> Someone (sorry, can't remember who) asked about Proton Beam Therapy and
> Photon Beam Therapy.
wborglum@sbcglobaldot.net Desert Denizen
keith340@webtv.net Keith Lundy
> Photon Beam Therapy.
Curtis is better qualified to explain this than I am, but here goes
anyway:
Electro-magnetic energy is called different things depending on
its wavelength. Some of the names we use for it are "light", "xrays",
"radio waves", "microwaves", and other names. They are all
the same thing but with different "wavelengths" and, what is really
the same thing, different "frequencies".
A "photon" is a quantum of electro-magnetic energy. "Quantum"
means an irreducibly small amount, an amount of energy of
which it is not possible to have something smaller.
I have not really heard of the phrase "photon beam therapy"
before. It might be that someone misheard "proton beam
therapy". However ordinary xray therapy could, in a way, be
called "photon beam therapy".
Of the different kinds of energy that might be used to treat cancer,
xrays are often chosen because they penetrate ordinary matter
like skin and soft tissue and can therefore get at the tumor
cells, and because they can carry enough energy to ionize
some of the molecules in our bodies, i.e. to knock protons or
electrons off the molecules - thus damaging them for their
normal function and, possibly, causing the xrayed cell to die.
Alan
Leonard Evens - 20 Oct 2006 16:30 GMT
>>Photon Beam Therapy.
>
[quoted text clipped - 25 lines]
>
> Alan
I think there are now some experimental treatments in which a substance
is injected in the blood which makes cancer cells susceptible to
radiation within the visible light region of the electromagnetic
spectrum. Then lasers or other devices are used to deliver radiation
to those cells which are destroyed in the process, leaving normal cells
unaffected. Such a therapy might be called photon beam therapy.
ron - 20 Oct 2006 17:09 GMT
> >>Photon Beam Therapy.
> >
[quoted text clipped - 32 lines]
> to those cells which are destroyed in the process, leaving normal cells
> unaffected. Such a therapy might be called photon beam therapy.
Tookad is an example of this approach, they use the term "photodynamic
therapy." They currently have several trials in progress or accruing,
Google "Tookad" for more information...Best wishes and good health, ron.
Alan Meyer - 23 Oct 2006 16:52 GMT
...
> > ...
> > I think there are now some experimental treatments in which a substance
[quoted text clipped - 7 lines]
> therapy." They currently have several trials in progress or accruing,
> Google "Tookad" for more information...Best wishes and good health, ron.
As I recall, Tookad is not really a light beam treatment. It
uses light to activate chemotherapeutic drugs.
The idea is that people are injected with a very dangerous drug
in a form that is inert until it is activated by light (this is done in
the dark I think!) Then catheters are used to insert a fiber optic
to the site of a tumor and a light beam is shined through the fiber,
activating the drug and killing nearby cells.
After a few hours, the drug degrades in the body and it is safe
for the patient to come out of the dark.
At any rate, that's my recollection of the process.
Alan
Alex - 23 Oct 2006 20:44 GMT
snip
> As I recall, Tookad is not really a light beam treatment. It
> uses light to activate chemotherapeutic drugs.
[quoted text clipped - 11 lines]
>
> Alan
I'm not sure why Alan describes the drug as very dangerous.
From PSA-RISING.com: "Tookad (from a Hebrew word meaning the warmth of
light) is a non-toxic, light-activated drug derived from chlorophyll.
Injected into the patient, it remains inactive until exposed to laser light.
Doctors shine the laser into the body through a catheter, targeting the
tumor using fiber optics. Once activated, Tookad produces a chemical that
blocks blood vessels in the immediate area and chokes off the tumour's blood
supply."
The web page also says the drug affects only tissues illuminated by the
fiber optics, sparing nearby tissues, and is eliminated in two hours.
Alex
Alan Meyer - 24 Oct 2006 22:22 GMT
> snip
> >
[quoted text clipped - 26 lines]
>
> Alex
Perhaps "very dangerous" was an inappropriate characterization.
The idea is that this drug kills cells in the human body and, for that
reason, I think of it as dangerous. In fact, the more dangerous the
drug, the more effective it is because the more deadly it is to
tumor cells.
I guess the danger question boils down to: What would happen
if the Tookad were light activated in some other part of the body
that didn't have cancer in it? Would it hurt us? A lot? Or a little?
I don't know the answer to that. If the answer is that it would only
hurt us a little, then my characterization of the drug as dangerous
is overstated.
Most of the chemotherapy drugs are dangerous in the sense
that they are cell killers. The trick in using them is to either find
chemicals, or delivery mechanisms, that kill more tumor cells
than non-tumor cells.
A lot of conventional chemotherapy drugs kill all dividing cells.
Cancer cells divide a lot and so may be killed. But the lining
of the stomach also has actively dividing cells (which is why
people get nauseous and vomit with chemotherapy) the hair
grows by dividing to produce more cells (which is why people
lose hair on chemotherapy). One reason chemotherapy is
less effective with prostate cancer than with fast growing cancers
is that, with prostate cancer, the rate of tumor cell division is
lower.
One day there will be very precisely targeted drugs that can
kill just the cells we want to kill. But we have a way to go
before we get there.
Alan