Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / Diseases and Disorders / Prostate Cancer / August 2006

Tip: Looking for answers? Try searching our database.

Prostate Cancer prevention

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
Dick Smith - 23 Aug 2006 21:21 GMT
Hello,
I'm curious as to what can be done that can help decrease the odds of
getting PCa. What type of foods etc can help? I believe Dr Catalona
listed lycopene capsules but what else? Is actually scarfing down
tomato paste a couple times a week a viable option as PCa *does* run in
my family! What about red wine? Should I consider that? Are there any
proper studies on this subject?
Beverley - 23 Aug 2006 22:33 GMT
We've had several discussions about foods and supplements and for the most
part I think most of us have concluded that they fall under "might help -
won't hurt" .  Any antioxidant should be part of the diet, and let's face it
junk food is junk food and no one needs it. So think about eating good
healthy foods. I think you will find more antioxidant qualities in a glass
of red grape juice than what you will find in wine but the sugar levels are
quite high in grape juice and wine is more fun. LOL

As for following certain diets? Well, our Mediterranean diet guy on the
group has PC, so does the vegetarian, the no carb guy has it, and the meat
and potato guy I'm married to has it. I think the only thing that would
protect you from the odds of PC is being a female and since that isn't going
to happen, because no matter what you can't change your DNA, the best you
can hope for is to be lucky.

You're probably doing what you should be doing. Eating healthy foods,
getting some exercise, getting a good night's sleep, and keeping your body
as healthy as possible is your best defense. Have your PSA routinely checked
and spend some time looking at treatment options in case you ever do have to
face the beast. If you do ever face it then you will probably have caught it
early, you will respond quickly with a treatment and get on with your life.

There are no magic bullets.
Bev

> Hello,
> I'm curious as to what can be done that can help decrease the odds of
[quoted text clipped - 3 lines]
> my family! What about red wine? Should I consider that? Are there any
> proper studies on this subject?
Alan Meyer - 24 Aug 2006 01:16 GMT
> We've had several discussions about foods and supplements and for the most
> part I think most of us have concluded that they fall under "might help -
> won't hurt"
...

There is a lack of solid scientific evidence proving the value of the
different prostate cancer diets.  So what Bev says here is probably
the most we can say for sure.

As I understand it, all of the evidence we have is of one of the
following
types:

  Test tube ("in vitro") studies.
  Mouse studies.
  Human studies, but with insufficient numbers, insufficient controls,
    or inadequate study designs.

You might think that mouse studies can be conclusive, but it
isn't so.  According to a standard textbook of cell biology that
I've been reading, the _great majority_ of cancer treatments that
work in mice don't work in humans.

Having said all that, I'll admit that I drink tomato juice every day
and take small amounts of vitamins and supplements.

If you want to pursue this further, I recommend going to the
Prostate Cancer Research Institute website search page at:

  http://www.prostate-cancer.org/search.html

If you enter the term "diet" you'll get many different doctors'
and other people's recommendations for diet and supplements.

    Alan
Alex - 24 Aug 2006 02:20 GMT
> There is a lack of solid scientific evidence proving the value of the
> different prostate cancer diets.

With respect, that is not exactly true.

Los Angeles attorney Thomas Mueller was diagnosed five years ago with PCa at
45, just after getting married. He rejected conventional medical treatments
in favor of an extreme diet -- essentially home-prepared macrobiotic food.
Over the following years biopsies and color doppler ultrasounds showed a
diminution of his cancer, and PSA has remained low and stable. I've talked
with him at length; he's a nice guy, and admits it is a very regimented way
to live and eat. Still, he and his doctors believe his diet has enabled him
to hold his PCa in check.

More detailed info is online at:
http://www.prostate-cancer.org/education/nutrprod/ScholzBlum_Nutrition_Prostate_
Cancer.html

or http://tinyurl.com/hmtyh

It's certain fair to say there is not a large body of scientific evidence
about the impact of diet, simply because very few of us would, during the
course of a study, successfully adhere to the extreme diet Tom has followed.

But unless you assume that his doctors are lying (they are also my doctors,
and I doubt that) or that his prostate cancer has coincidentally and
spontaneously regressed, his example is evidence that diet (and exercise)
can fairly dramatically impact PCa.

Alex
Info@DrYew.com - 24 Aug 2006 05:55 GMT
Diet definitely plays a role. Maybe not a "curative" role as you
suggest, but there is a
considerable amount of research that suggests that certain nutrients
have activity
against prostate cancer. These include:
  Vitamin E   100IU
  Vitamin D   1600IU
  Selenium    200 mcg
  Lycopene    30mg
  Soy Isoflavones   50mg

There is a company that provides "pharmaceutical grade" supplements,
founded by
physicians (not me) that provides links to many research articles on
the role of
nutrients in urologic conditions, including prostate cancer:
http://www.theralogix.com

Also, a PDF handout on nutrition and prostate cancer is here:
http://www.theralogix.com/images/provider_support/Nutrition%20Prostate%20Cancer.pdf

The obvious benefit here is the lack of any side-effects. Unlike Mr.
Meyer & Mueller's docs, I personally do not believe these can be
curative. However, I am a firm believer in using these supplements in
select patients: older or ill patients with low-risk prostate cancer
who are essentially "observing" their cancer, but would like to do
anything non-invasive they can to treat their cancer, patients who I do
a da Vinci robotic laparoscopic Prostatectomy (dVP) on who have
high-risk features (gleason 7+). I do direct these patients to the
Theralogix website so they can collect information. I think the website
is pretty open about their content formulations. They can order it on
the website, or just jot down the ingredients and then go price
shopping on their own. I think there's a lot of good information there,
so check it out. Just so you know, I do NOT have any financial
affiliation with that company (or any other company). If you want to
order from the website or by phone, you can use code 40889 to get a
small discount.

===
http://www.DrYew.com
http://www.SanDiegoRoboticProstatectomy.com

> > There is a lack of solid scientific evidence proving the value of the
> > different prostate cancer diets.
[quoted text clipped - 24 lines]
>
> Alex
Info@DrYew.com - 24 Aug 2006 05:59 GMT
Oh yeah.. I forgot to mention 2 other important groups that I suggest
nutritionals to:
(1) patients with PIN on biopsy (high grade prostatic intraepithelial
neoplasia), a pre-cancerous appearance to the cells.
(2) patients with family history of prostate cancer but otherwise
normal PSA, DRE, etc..

> Diet definitely plays a role. Maybe not a "curative" role as you
> suggest, but there is a
[quoted text clipped - 66 lines]
> >
> > Alex
Bob Anthony - 24 Aug 2006 14:44 GMT
The "a healthy heart diet is a healthy prostate diet" is a bit
confusing. Just before my robotic procedure I had to be medically
cleared. There was some artifact on my stress test so I went for an
angiogram which turned out to be a false positive. The Chief of
Cardiology at Cleveland Clinic did the procedure and was amazed that not
only did he not find anything wrong with my heart, but that he saw no
plaque anywhere. All I remember him saying as I came off of the happy
juice was that "what ever you're doing, keep doing it!" He came over to
me not once, but twice. I was 53 at the time. (My surgery was 12/04).
I always exercised, (both weight baring and aerobic) keep my weight at
ideal levels, ate pretty well, took supplements, drank red wine with
dinner, ate cooked tomatoes, (marinara sauce just happens to be one of
my favorites and I make it myself) and took pretty good care of myself
in general. For all intents and purposes, I should not have gotten PCa.
I should have been very low risk to develop PCa. But I did anyway.
Since, I've heard,(and read) from others here on this ng and elsewhere
that had practiced very healthy diets and consumed very little or no
hydrogenated fats, saturated fats, or trans fats. Guess what...they got PCa.
The Asian diet probably is healthier that the western diet in general
because of the lack of these fats consumed by comparison. But, there is
a higher incidence of other cancers, such as stomach cancer for
instance. Go figure.
I think the medical community needs to not only map the human genome,
but to read and use that map in order to realize undisputed disease
prevention and cures.

B.A.
I.P. Freely - 25 Aug 2006 06:47 GMT
> Diet definitely plays a role. Maybe not a "curative" role as you
> suggest, but there is a
> considerable amount of research that suggests that certain nutrients
> have activity
> against prostate cancer.

WebMD at http://health.webmd.com/cgi-bin21/DM/y/eozT0LNg230CBe0omh0E3 
says otherwise:

July 18, 2006 -- Cancer patients spend billions a year on vitamins and
dietary supplements, but there is no proof that these products -- or
other nutrition strategies -- are effective for treating or preventing
the disease, a new analysis shows.

I.P.
JohnHace - 25 Aug 2006 16:53 GMT
> July 18, 2006 -- Cancer patients spend billions a year on vitamins and
> dietary supplements, but there is no proof that these products -- or
> other nutrition strategies -- are effective for treating or preventing
> the disease, a new analysis shows.

Well, that's true. And also, there is no proof that God exists, but I
talk to him every day.

Since my first PSA test, I have added nunerous supplements and diet
changes. I think that must have something to do with my PSA drop.
Granted, I had a DRE and sexual activity prior to my first PSA, but
everyone says that should only cause a point or two change. Mine
dropped from 20.3 to 13.8.

That's not proof, but I'll keep taking the supplements.

In a few weeks, before I have any treatment, I'll check it again and I
bet it will drop some more.

John
DrYew.com - 26 Aug 2006 04:47 GMT
Believe me, I come from somewhat traditional cancer surgery training
where
"a chance to cut is a chance to cure". But, I recognize that there is
evidence
that certain nutritional supplements appear to have an impact on PSA,
and
theoretically therefore, possibly prostate cancer progression. I agree
this is
not a direct impact, and probably only a marginally indirect impact at
best
on prostate cancer outcomes. Also, I agree that there is no evidence to
date
of any kind of survival benefit. So why advocate it? Because there are
NO
side-effects! I wish I could say the same about my surgery, or
radiation, or
lupron. If I have a patient I do a daVinci robotic laparoscopic
Prostatectomy
(dVP) on and he has gleason 7, margin neg path... I consider him cured.
They almost always have PSA less than 0.1 at 1 month. But, I still take
a
few minutes to tell them that they might consider taking certain
supplements.
Likewise, for the patient who wants to feel like they are being
pro-active
in the management of their disease, but are not candidates for more
traditional therapies. (Eg, the vibrant 90yo man with a PSA of 30 and a
firm prostate) I won't biopsy him, but I would suggest supplements.

===
http://www.DrYew.com
http://www.SanDiegoRoboticProstatectomy.com
*IMPORTANT* Any comments by me are for general informational purposes
only, and should never be used to diagnose or recommend  treatments for
any condition without face-to-face consultation with a qualified
health-care provider. Thank you.
===

> > Diet definitely plays a role. Maybe not a "curative" role as you
> > suggest, but there is a
[quoted text clipped - 11 lines]
>
> I.P.
Alan Meyer - 24 Aug 2006 17:02 GMT
There was a recent review of published studies of the role
of supplements in fighting cancer.  It was published in the
July 19, 2006 issue of the _Journal of the National Cancer
Institute_, by Anna A. Davies, et. al.

Here are the conclusions from the abstract:

   Conclusions: The impact of most nutritional interventions
   cannot be reliably estimated because of the limited number of
   trials, many of which were of low quality. There is no
   evidence that dietary modifi cation by cancer patients
   improves survival and benefi ts disease prognosis. [J Natl
   Cancer Inst 2006;98: 961 - 73]

It was discussed on this newsgroup.  Search Google groups for the
title: "No indication nutrition helps fight cancer" (with quote
marks) to find it.  The thread was begun on July 19, 2006 by I.P.
Freely.

I'm not competent to evaluate the article, but the reviewers of
the Journal of the NCI probably are and they thought enough of it
to publish it.

The article doesn't imply that nutritional interventions do no
good, only that the level of evidence for them is not yet raised
to a high enough level to come to the scientific conclusion that
they definitely do do good.

We all know individual cases, a few have been posted on this
newsgroup and the one you cite Alex is another, where diet and/or
supplements _seem_ to have had a positive impact.  And as I said
before, I take supplements myself.  But the scientific data
behind this doesn't yet appear conclusive - or at least that's
what the JNCI says.

   Alan
I.P. Freely - 25 Aug 2006 18:40 GMT
>> There is a lack of solid scientific evidence proving the value of the
>> different prostate cancer diets.
[quoted text clipped - 22 lines]
> spontaneously regressed, his example is evidence that diet (and exercise)
> can fairly dramatically impact PCa.

Once again, "anecdotal evidence" is an oxymoron. If we considered
anecdotes to be "evidence", we could "prove" ANYTHING. Just because a
WWII tailgunner fell out of his bomber at 10,000 feet with no parachute
and walked away doesn't "prove" skydivers don't need parachutes; it just
proves that ONE GUY happened to land in the upper branches of giant
snow-packed fir trees which cushioned his fall. And many cases of
"terminal cancer" of various types have just vanished. Mueller could
have had spontaneous remission, his immune system may have rallied, his
cancer could have just up and run off when it learned its host was a
freaking LAWYER, his diet and exercise may have helped, or maybe Bill
Clinton felt his pain and absorbed its negative vibes. But it proves
nothing except that "a macrobiotic diet is not immediately fatal to all
adherents".

I.P.
Steve Kramer - 25 Aug 2006 20:25 GMT
>> Los Angeles attorney Thomas Mueller was diagnosed five years ago with PCa
>> at 45, just after getting married. He rejected conventional medical
[quoted text clipped - 4 lines]
>> it is a very regimented way to live and eat. Still, he and his doctors
>> believe his diet has enabled him to hold his PCa in check.

> Once again, "anecdotal evidence" is an oxymoron. If we considered
> anecdotes to be "evidence", we could "prove" ANYTHING. Just because a WWII
> tailgunner fell out of his bomber at 10,000 feet with no parachute and
> walked away doesn't "prove" skydivers don't need parachutes; it just
> proves that ONE GUY happened to land in the upper branches of giant
> snow-packed fir trees which cushioned his fall.

If true, it proves that it is possible to survive a 10,000 free fall.  Just
as Mueller's story is true, it proves that it is possible to survive cancer
without surgery, radiation or HT.

Though, I admit, I suspect both stories.
I.P. Freely - 26 Aug 2006 01:16 GMT
>>> Los Angeles attorney Thomas Mueller was diagnosed five years ago with PCa
>>> at 45, just after getting married. He rejected conventional medical
[quoted text clipped - 17 lines]
>
> Though, I admit, I suspect both stories.

1. Flight Sergeant Nicholas Alkemade jumped from his Lancaster at 18,000
 feet [OK, my 10,000 feet was in error; I read the story over 40 years
ago) to escape the holocaust of his blazing bomber, leaving behind his
useless parachute that had been torn to shreds by shrapnel. His headlong
fall was broken by a fir tree and he finally landed in an eighteen inch
snow-drift, without a single fracture. Naturally, the Luftwaffe
authorities were highly suspicious of his story of falling from such a
height without a parachute, but on investigation they found his shredded
and unused ‘chute in the crashed remains of the aircraft. Tail gunners
had to stash their 'chutes inside the fuselage, and when Alkemade opened
the rear hatch of his turret, he found flames raging inside the plane
and his only means of escape a blazing mass of silk. Faced with the
choice of falling to his death or burning to a crisp, he rotated the
turret and did a back somersault into space, 18,000 feet above Germany.
Falling at speeds of up to 120mph, it would have taken him about two
minutes to hit the ground. He was fantastically lucky. First, he blacked
out during the fall, ensuring his body would not be dangerously rigid
and tense on impact. Second, he fell into a dense pine forest, whose
branches broke his fall, and then into a deep snowdrift. He survived
with nothing worse than a somewhat twisted ankle. Alkemade's case is
particularly well-researched because the Germans who found him
discovered that his parachute harness had not been used and suspected
him of being a spy. A Luftwaffe probe, involving an investigation of the
crashed bomber, proved the airman's story, and Alkemade was shipped off
into captivity. He survived the war and eventually passed away on 22
June 1987.

2. We already knew some people survive cancer, that it sometimes
disappears, but that is not evidence that Mueller's macrobiotic diet
affected his cancer.

I.P.
Alex - 27 Aug 2006 23:14 GMT
>>> There is a lack of solid scientific evidence proving the value of the
>>> different prostate cancer diets.
[quoted text clipped - 38 lines]
>
> I.P.

I stand corrected. I.P. is correct that one instance is not "evidence." On
the other hand, there are many studies indicating that diet appears to be
linked to the incidence of prostate cancer in a given population, such as
the differences in PCa rates of Japanese men who follow traditional diets in
Japan versus Japanese men who emigrate to Hawaii or the United States and
switch to a Western diet.

That by no means supports the notion that diet will have an impact AFTER
prostate cancer is diagnosed. But it does suggest some linkage between diet
and the body's tendancy to fight the cancer.

On the other hand, if becoming a lawyer would inevitably produce a
spontaneous remission -- well, that's a pretty high price to pay just to
overcome cancer! (g)

Alex
ron - 28 Aug 2006 00:06 GMT
Alex wrote...snip...
> I stand corrected. I.P. is correct that one instance is not "evidence." On
> the other hand, there are many studies indicating that diet appears to be
[quoted text clipped - 6 lines]
> prostate cancer is diagnosed. But it does suggest some linkage between diet
> and the body's tendancy to fight the cancer.

Hi Alex...I tend to believe that diet does have a beneficial effect on
PCa.  No particular reason, just what I choose to believe until more
information comes along.  Like Bev said, file it under can't hurt,
might help.  But rather than saying that the PCa data on Japanese
natives and emigres "suggests some linlage", I might say that it is
consistent with some linkage.  Other factors creep into this example
and make analysis less straightforward than it might at first appear.
For example,

Do emigres tend to live longer than natives?
Do emigres have better access to health care and screening?
In Japan, anything related to urologic disorders is difficult to speak
about.  Does ths mean that PCa is under-reported on death certificates?

All of these variables could cause emigre PCa rates to be higher than
native rates.  And this is a short list, other variables exist as well.

Diet is associated with cardiovascular disease.  If a healthy diet
reduces cardiovascular deaths, then wouldn't it be (sadly) ironic if
some of these men who would have died from a heart attack now live
longer and die from PCa, driving the rate up.  Let's hope not...Best
wishes and good health, ron
Alex - 28 Aug 2006 07:21 GMT
> Alex wrote...snip...
>> I stand corrected. I.P. is correct that one instance is not "evidence."
[quoted text clipped - 33 lines]
> longer and die from PCa, driving the rate up.  Let's hope not...Best
> wishes and good health, ron

Ron, the points you raise are interesting but speculative, and certainly are
ones that a researcher would anticipate and, if present, correct for. These
studies include men in Japan, Italy, Greece, which have radically different
cultural mores. And I am not sure American men are dramatically more
comfortable than their counterparts in other countries about discussing
their urological situation.
From Prostate-Cancer.com:
"Traditional Diet and Prostate Cancer -- Men from Italy and Greece who
consume a traditional Mediterranean diet of fresh fruits and vegetables,
fish, and olive oil have a lower incidence of the disease. Men from Japan
who consume a traditional rural diet of fish, rice, and green tea also have
a very low incidence of prostate cancer. Both of these diets are examples of
also preventative dietary habits.
"If men from any of these groups move to the United States, within two
generations, their chances, probably due to dietary changes, increase to
that of a typical Caucasian man. Researchers are also finding that as Japan
becomes more Westernized, and its citizens consume larger amounts of Western
food, the disease rate tends to increase."
Alex
NICK - 24 Aug 2006 06:03 GMT
> I'm curious as to what can be done that can help decrease the odds of
> getting PCa. What type of foods etc can help?

http://tinyurl.com/h4b9a

 Dietary changes and stress management MAY attenuate PCa

Saxe GA; Major JM; Nguyen JY; Freeman KM; Downs TM; Salem CE
Department of Family & Preventive Medicine Moores UCSD Cancer Center

 I don't know where you're located, but............

Gordon Saxe, M.D., Ph.D. UCSD, is the speaker at the
Prostate Cancer Research & Education Foundation
Saturday, September 9   10:00   Alvarado Hospital
6655 Alvarado Road, San Diego, CA
Topic:  The Macrobiotic Diet in Prostate Cancer
                     (aka:   plant-based diet)
Info@DrYew.com - 24 Aug 2006 08:43 GMT
Thanks.. I know these guys. They're just down the street!

I agree completely. If a patient has PSA recurrence that is slowly
creeping or low-stable after either surgery or radiation, and they are
otherwise completely asymptomatic, I think nutritional therapy is a
reasonable approach with no side-effects.

===
http://www.DrYew.com
http://www.SanDiegoRoboticProstatectomy.com

> > I'm curious as to what can be done that can help decrease the odds of
> > getting PCa. What type of foods etc can help?
[quoted text clipped - 14 lines]
>  Topic:  The Macrobiotic Diet in Prostate Cancer
>                       (aka:   plant-based diet)

Rate this thread:






 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2008 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.