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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2006May 2006 follow up: "Is melanoma simply a Vitamin D deficiency cancer?"
TO: All melanoma researchers, doctors, and patients. Examine any book or website about melanoma, or visit any dermatologist's office, and you will find plentiful information on how to minimize or eliminate your sun exposure, but none on how to optimize it. Minimizing sun exposure is very easy to accomplish; indeed, it is foolproof. Sunscreens, clothing, and staying indoors are commonly prescribed approaches, but even without any of them, a suntan naturally inhibits carcinogenic doses of ultraviolet radiation. Optimizing sun exposure is a much more difficult problem--particularly for those with fair skin in non-native climates--because it involves avoiding extremes. Knowing whether an exposure regimen is too much or not enough requires specialized attention to the skin. Note that some people in some climates have a window of opportunity lasting literally minutes in which they must acquire the necessary Vitamin D3, thus leaving their skin most susceptible to a deficiency and melanoma. James Semmel Albuquerque, New Mexico reference: http://www.mpip.org/bb/shtml/330498.shtml Last month's follow up to the 3rd annual discussion: "Is melanoma simply a Vitamin D deficiency cancer?" > TO: All melanoma researchers, doctors, and patients. To the best of my knowledge, of the several hundred people I've seen come through here, none had a pressing problem with melanoma; none were melanoma researchers; and none were melanoma researchers. As a matter of fact, none were melanoma frauds or spammers.... until now. Steve, I raise the question, "Is melanoma simply a Vitamin D deficiency cancer?" in this newsgroup because of its relevancy to the current debate about Vitamin D and prostate cancer. Specifically, melanoma rates have alarmingly increased during the last quarter-century as Vitamin D deficiency has become widespread, but prostate cancer rates have not exhibited such growth. Thanks, james > melanoma > rates have alarmingly increased during the last quarter-century as > Vitamin D deficiency has become widespread, but prostate cancer rates > have not exhibited such growth. But the public has "moved outdoors" over the last few decades, too. Most of my friends are involved in sports which keep them in the desert sun all day. As you know, that's brutal stuff at >4,000 feet in the SW. I.P. I.P., You raised a good point. Excessive sunlight exposure darkens and thickens the skin via tanning; this natural protective mechanism inhibits the synthesis of Vitamin D3. In other words, too much sun causes a deficiency in Vitamin D and, in my opinion, melanoma. I think this is the single hardest principle for academic researchers to grasp: A balance must be maintained between getting too much sunlight and not enough. james > I.P., > > You raised a good point. Excessive sunlight exposure darkens and > thickens the skin via tanning; this natural protective mechanism > inhibits the synthesis of Vitamin D3. In other words, too much sun > causes a deficiency in Vitamin D and, in my opinion, melanoma. Or just one or two bad sunburns in childhood, apparently regardless of how much sun we get the rest of or lives. ANY tan is evidence of skin damage. Monks who wear full robes all the time have skin like a baby's butt. I.P. I.P., Again it comes down to whether a person is moderating their sun exposure. In the last quarter-century, doctors have advised getting no sunshine whatsoever, and that certainly caused a rise in a deadly Vitamin-D-deficiency disease (which I claim is melanoma). In other words, we need some sunlight to remain healthy (and alive!), but too much sunlight is simply too much of a good thing, because it inhibits synthesis of Vitamin D3 via natural tanning. Thanks, james Many US men with PCa are also vitamin-D deficient. Is the melanoma rate amongst men with PCa higher than the general US rate?..Ron > Steve, > [quoted text clipped - 7 lines] > Thanks, > james Well, Steve, not a spammer. He sticks around, he responds rationally and logically. You're crabby today! It's the T..... (but that was funny about never having seen a melanoma researcher or spammer here!) > Well, Steve, not a spammer. He sticks around, he responds rationally > and logically. You're crabby today! It's the T..... > > (but that was funny about never having seen a melanoma researcher or > spammer here!) Not crabby, ... just fed up with assaults on our Prostate Cancer newsgroup by people with ulterior motives that range from nuisance to fraud. Maybe a tad premature, but not crabby. If it turns out to be the former, I'll apologize and make reference to alt.support.cancer. However, I am curious as to what the "T...." is. I haven't had my coffee this morning and am having a brain cramp.  SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05, 2/06 PSA .07 .05 .06 .09 .08 .132 Non Illegitimi Carborundum > However, I am curious as to what the "T...." is. I haven't had my coffee > this morning and am having a brain cramp. Wrong Steve, you're the *Other, other* Steve. Sorry! Confusion abounds with first names of Dave, Dan, Steve, et al. How about Steve 2000, Steve 2003 and Steve 2006? I guess you'll have to get permmission from Misters Jordan and Fitzhugh. :-) SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05, 2/06 PSA .07 .05 .06 .09 .08 .132 Non Illegitimi Carborundum >> However, I am curious as to what the "T...." is. I haven't had my coffee >> this morning and am having a brain cramp. > > Wrong Steve, you're the *Other, other* Steve. Sorry! |
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