A biopsy of the prostate? W/ PSA <.01? If he has PCa it will be a blow
to everything we know about PSA as a reliable biomarker. Also, this
will be the first time I have heard of PCa found via a urine test. If
PCa could be found when PSA is undetectable, it would be the test of
choice. On the other hand, that is the way bladder cancer is often
found. If it is PCa it is way early so no need to rush into a biopsy,
and I certainly would not have one unless and until my uro has
explained why this isn't bladder cancer. He should perhaps have a
cytoscopic examination of the bladder. And get him in a bladder cancer
group too.

CAVEAT: The foregoing assumes typical adenocarcinoma of the prostate;
it is possible (but it would be rare on initial Dx) that he has small
cell carcinoma, which does not result in high PSA. Or transitional cell
carcinoma, which is similar to bladder cancer and may be more apt to
show up in urine. But I would think they would have known what kind of
Ca it is from the pathology of the urine. Perhaps they do - are you
sure he has told you everything? And you us?

Bill Denton
RP 2/12/02
PSA .67
Memphis