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Medical Forum / Diseases and Disorders / Prostate Cancer / March 2006

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update John Preston

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Carolyn Preston - 14 Mar 2006 16:08 GMT
Well things are a changing, the stage one clinical trial  (IV
antibody) that John started a couple of months ago has been abandoned,
this is due to a rising PSA and disease progression. After 2 cycles of
treatment Johns PSA is now 295 so it obviously was not working. We
have an appointment at Royal Marsden to discuss another trial, it is a
phase 2 chemotherapy trial we will know more details next week. John
has been getting a lot of discomfort and the hospice Macmillan  nurse
has sorted out a pain management plan, which includes oramorf should
John need it. John will also get spot radiation on a mass on his jaw
that is causing him problems. well apart from that we are ok and going
onward into the fog. Best wishes to all.
Love
Carolyn Preston
xx
Steve Kramer - 14 Mar 2006 17:26 GMT
> Well things are a changing, the stage one clinical trial  (IV antibody)
> that John started a couple of months ago has been abandoned, this is due
[quoted text clipped - 7 lines]
> well apart from that we are ok and going onward into the fog. Best wishes
> to all.

I am damned sorry to hear this, Carolyn.  As best as I can tell, John and I
are very nearly the same age and I shudder to think what it would be like to
be at this stage already.

You (plural) are in my thoughts and prayers.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06
PSA  .07 .05 .06 .09 .08 .132
Non Illegitimi Carborundum

Carolyn Preston - 14 Mar 2006 18:41 GMT
> I am damned sorry to hear this, Carolyn.  As best as I can tell, John and I
> are very nearly the same age and I shudder to think what it would be like to
> be at this stage already.
>
> You (plural) are in my thoughts and prayers.

Thankyou, John is 51yrs old. we know we are in troubled waters however we are not miserable or moping around
we intend to take several holidays this year Scotland and the Orkney Isles in June, southern Ireland for my little bruvs wedding in July, Poole in Dorset in August and maybe Florida in November, if John has to have treatments during the holidays we will just have to pop into London have treatment and then back to holiday fun!!!!!
All this as well as having a severely disabled 8 year old daughter hey ho what fun.....

See our family

our son and daughter
Kevin (22yrs) and Stacey(16yrs)
http://img.photobucket.com/albums/v610/gsx14rider/PB180015.jpg

John Carolyn Preston

http://img.photobucket.com/albums/v610/gsx14rider/P1070005.jpg

our daughter Lucy-mae
http://img.photobucket.com/albums/v610/gsx14rider/PA210001.jpg

John and his bike
http://img.photobucket.com/albums/v610/gsx14rider/me800x600.jpg

Hope you like the photos.
Carolyn
Steve Kramer - 14 Mar 2006 20:55 GMT
 > I am damned sorry to hear this, Carolyn.  As best as I can tell, John and I
 > are very nearly the same age

 Thankyou, John is 51yrs old.

 __ Yup, that's where I'm at.  52 in September.

 we know we are in troubled waters however we are not miserable or moping around
 we intend to take several holidays this year Scotland and the Orkney Isles in June, southern Ireland for my little bruvs wedding in July, Poole in Dorset in August and maybe Florida in November,

 __ That's quite an itinerary.  It's more than I have planned for the next five years.

 See our family

 __ Nice family.  

 --
 PSA 16 10/17/2000 @ 46
 Biopsy 11/01/2000 G7 (3+4), T2c
 RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
 PSA  .1  .1  .1  .27  .37  .75
 EBRT 05-07/2002 @ 47
 PSA  .34 .22 .15 .21 .32
 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05, 2/06
 PSA  .07 .05 .06 .09 .08 .132
 Non Illegitimi Carborundum
Alan Meyer - 14 Mar 2006 23:02 GMT
I loved the photos.  We are so used to seeing each other
as just bits of text on the newsgroup that its great to see
the real images of human beings behind the text.

Two sets of clinical trials that have intrigued me are those
for phenoxodiol and for the cancer vaccines.  Like everything
else, these are highly experimental and may very well not
pan out, but the early testing showed some promise.  I
don't know if either is being tested across the pond.  A lot
of the original work on both of these was actually in
Australia.

The "vaccines" are not for prevention like most vaccines,
but for treatment.  The idea is to sensitize the patient's
own immune system to something in the tumor cells and
thereby get the immune system to attack them.

I wish you, John, and the rest of your family the very
best.

   Alan
Alan Meyer - 15 Mar 2006 00:41 GMT
I loved the photos.  We are so used to seeing each other
as just bits of text on the newsgroup that its great to see
the real images of human beings behind the text.

Two sets of clinical trials that have intrigued me are those
for phenoxodiol and for the cancer vaccines.  Like everything
else, these are highly experimental and may very well not
pan out, but the early testing showed some promise.  I
don't know if either is being tested across the pond.  A lot
of the original work on both of these was actually in
Australia.

The "vaccines" are not for prevention like most vaccines,
but for treatment.  The idea is to sensitize the patient's
own immune system to something in the tumor cells and
thereby get the immune system to attack them.

I wish you, John, and the rest of your family the very
best.

   Alan
dale.j. - 15 Mar 2006 01:53 GMT
Wonderful pictures.  Thankyou.

Dale j.

Signature

Email:  dalej2@mac.com

Lorelei - 25 Mar 2006 07:54 GMT
Hi Carolyn and John, we have been wondering how it has been going.
Kkeep up the good fight and keep enjoying each other. It's great that
he has so many opportunities for clinical trials in which to
participate.

Curt and I seem to have most of our differences worked out. His
acceptance of his brain mets has been crucial in this process. His PSA
is now in the 1100's but he's still hanging in there. having him back
home has been very good for his health as I can help him remember
things he forgets ( like meds )

take care both of you and I appreciate the pictures.
Lori and Curt Miller
Steve Kramer - 26 Mar 2006 02:21 GMT
Thanks for the update Lori.  I was just thinking of you yesterday.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06
PSA  .07 .05 .06 .09 .08 .132
Non Illegitimi Carborundum

> Hi Carolyn and John, we have been wondering how it has been going.
> Kkeep up the good fight and keep enjoying each other. It's great that
[quoted text clipped - 9 lines]
> take care both of you and I appreciate the pictures.
> Lori and Curt Miller
Beverley - 29 Mar 2006 02:23 GMT
Lori,
I think of you and your children often. I'm glad to hear you are there now
to help Curt and he is accepting your help.
((HUGS))
Bev

> Hi Carolyn and John, we have been wondering how it has been going.
> Kkeep up the good fight and keep enjoying each other. It's great that
[quoted text clipped - 9 lines]
> take care both of you and I appreciate the pictures.
> Lori and Curt Miller
carmensrt@gmail.com - 29 Mar 2006 16:10 GMT
> Hi Carolyn and John, we have been wondering how it has been going.
> Kkeep up the good fight and keep enjoying each other. It's great that
[quoted text clipped - 9 lines]
> take care both of you and I appreciate the pictures.
> Lori and Curt Miller

Dear Lori,
I was wondering how you and Curt were doing so I looked you up.  I know
you went through quite a rough patch with him and am relieved to see
that things are a bit smoother for you two now.  All I can do is offer
my best wishes for you and he that you have the strength to bear up for
each other through the days to come.  My email is good.

Take care,
Carmen from ASDLC

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