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Medical Forum / Diseases and Disorders / Prostate Cancer / March 2006

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Hello, God Bless, got back biopsies

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dave481 - 27 Feb 2006 19:51 GMT
Got back biopsies and they have Adenocarcinoma in all 12 samples (he
took 14, don't know what happen to the other 2). Anyhow, on the Gleason
scale I had one-7, two-8s, six-9s, and two -10s. The uro said that is
an aggressive cancer and "appears" advanced.  He ran a camera in
through my penis and said the bladder was clear. I've had moderate pain
in my hip and leg bone for about 3 months so tomorrow I go to an
imaging center for a CT of abdomen and pelvic. Then to the nuclear part
of that place for a bone scan. This all came about because of a
colonoscopy that shows a "larger than golf ball" tumor in my colon. So
all the Drs. will be putting their heads together to form a battle plan
based on tomorrows results.   Does anyone know anything about this type
of cancer you can share? Or the reliabilty of the Gleason scale?  I
sure have enjoyed the feedback here. Oh, and. Can you ride a horses
after prostate removal? Or is the pain too great?
Thank-you and God Bless You all
David

p.s. this is such an "indignant" disease.
Steve Jordan - 27 Feb 2006 20:30 GMT
> Got back biopsies and they have Adenocarcinoma in all 12 samples (he
> took 14, don't know what happen to the other 2). Anyhow, on the Gleason
> scale I had one-7, two-8s, six-9s, and two -10s. The uro said that is
> an aggressive cancer and "appears" advanced.  
(snip)

I am very very sorry to learn of this.

To be certain of the results, and because the Gleason scores will
virtually control what is done from here on, I recommend that the biopsy
slides and tissue block be sent for a second opinion to one of the labs
that specialize in such studies. The cost should be covered by insurance
and Medicare, and is in any event only around $350. Bostwick reported on
my specimens in about a week.

Information on labs can be found on the website of the Prostate Cancer
Research Institute at
http://www.prostate-cancer.org/resource/special.html#pathology

Exploration of the site will lead Dave to a huge fund of essential
information.

Based upon Dave's report about his hip and leg (femur?) and subject to
confirmation by actual tests, I have to suspect that the PCa has
metastasized.

It is time to consult a medical oncologist. There is much that can be done.

Regards,

Steve J

"Never -- never -- never give up!  Never go gently.  There will be plenty of
gentle after we die, so until then -- fight -- control the rhythms and tempo
of the dance, even when you have to let the PCa dancing bear lead for awhile
-- even when you have to wear the lead suit as you dance -- never let the
bear set the rhythm and tempo of your dance with life -- when the bear
finally takes control, it will be a very hollow feeling for him, because I
will be gone -- dancing in a better place."
--E. B. (Burns) Mixon, PCa survivor, June 14, 2005 on The Prostate
Problems Mailing List
Thank you, Burns. Live long and prosper.
Ron B - 27 Feb 2006 21:01 GMT
Dave, we all wish you the very best.

The smart guys here and your docs will help you get back on the horses.

Follow their advice...do the treatments...and I'm confident that you
will ride again.

Giddyup.  :-)

My best wishes are sent to you,

Ron B.

Chicago
judamd@aol.com - 27 Feb 2006 20:39 GMT
Adenocarcinoma is run-of-the-mill prostate cancer which is what just
about everyone here has or has had.  Your uro is correct when he says
it is aggressive.  As for the Gleason scores, they're not too difficult
for a pathologist to determine.  If you have a dozen different
pathologists read them, you'll get a few small variations such as one
guy calling one sample a six instead of a seven, but in your case it's
pretty certain you have a lot of high numbers no matter how many times
they're looked at.  As for riding a horse post-op, how soon do you want
to ride?  It'll hurt like hell if you try it the first week but there's
no reason you can't ride after everything heals up.  Looks like you
have a tough row to hoe what with the colon stuff and now this.  Here's
hoping the docs can get you all patched up and back on that horse
again.  All the best.
Dave Perry
Steve Kramer - 27 Feb 2006 23:45 GMT
> Got back biopsies and they have Adenocarcinoma in all 12 samples (he
> took 14, don't know what happen to the other 2). Anyhow, on the Gleason
[quoted text clipped - 12 lines]
> Thank-you and God Bless You all
> David

Very few here (3 in 4 years) have had a Gleason of 10.  I believe they will
find that your tumor is a prostate cancer tumor in your colon as opposed to
colon cancer.  While that is bad news, it might not be as bad as a colon
cancer tumor which, I believe, is more deadly.

There is probably no harder analysis in medicine that determining the
difference between Gleasons, but your 10s are not going to be read by others
as 7s.  You have very serious prostate cancer.

Riding horses after normal prostate cancer is not a problem.  I assume they
will have to cut out the colon tumor and resection the colon which may be
the larger question regarding horseback riding.

God bless you too, David.  I sure am sorry for your dx.  Please keep us
posted on your other test results.
J - 28 Feb 2006 00:44 GMT
> "dave481" <daave481@yahoo.com> wrote in message
> > Got back biopsies and they have Adenocarcinoma in all 12 samples (he
[quoted text clipped - 15 lines]
> find that your tumor is a prostate cancer tumor in your colon as opposed to
> colon cancer.

How would they know, since they're both adenocarcinomas ?
Which opens up the question of post-op treatment.
Depending on the pathology report of the colon tumour, post op chemo is
sometimes advised.
Which leaves him (taking) post op chemo for the colon and post op hormone
therapy for the prostate ?
J
Note: crosspost for opinion elsewhere

> While that is bad news, it might not be as bad as a colon
> cancer tumor which, I believe, is more deadly.
[quoted text clipped - 6 lines]
> will have to cut out the colon tumor and resection the colon which may be
> the larger question regarding horseback riding.
Steve Kramer - 28 Feb 2006 01:26 GMT
> How would they know, since they're both adenocarcinomas ?

I don't know.  But, I'm almost certain that they can.  Especially now that
they know the DNA of prostate cancer... or is it the prostate cancer
chromozome of DNA?

> Which opens up the question of post-op treatment.
> Depending on the pathology report of the colon tumour, post op chemo is
> sometimes advised.
> Which leaves him (taking) post op chemo for the colon and post op hormone
> therapy for the prostate ?

I think it is very early to worry about that, J.  He still has scans and
other tests to complete to determine if he has metastases on his bones and
elsewhere.  If he has both kinds of cancers, he's going to have to get
applicable treatment for each and both cannot be contraindicated with each
other.  I.P. is the expert in this area.

I suspect that if he has colon and prostate cancer and no other mets, they
will cut out the colon tumor and radiate the prostate.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06
PSA  .07 .05 .06 .09 .08 .132
Non Illegitimi Carborundum

I.P. Freely - 28 Feb 2006 07:28 GMT
> I suspect that if he has colon and prostate cancer and no other mets, they
> will cut out the colon tumor and radiate the prostate.

I can't imagine using RT when they must open him up anyway to get the
CC. As long as they're in there, may as well grab the prostate at the
same time and do the pathology. Prostate excision is the more exacting
surgery, especially if nerve sparing is done, but the CC surgery is
arguably the bigger recovery issue simply because it's a bigger zipper
and requires more hospital time.

I.P.
Steph - 28 Feb 2006 08:18 GMT
>> I suspect that if he has colon and prostate cancer and no other mets,
>> they will cut out the colon tumor and radiate the prostate.
[quoted text clipped - 7 lines]
>
> I.P.

Resection of a colon cancer, especially in the transverse or right colon, is
a MUCH simpler and less morbid surgery than radical prostatectomy
I.P. Freely - 28 Feb 2006 17:57 GMT
>>> I suspect that if he has colon and prostate cancer and no other mets,
>>> they will cut out the colon tumor and radiate the prostate.
[quoted text clipped - 9 lines]
> Resection of a colon cancer, especially in the transverse or right colon, is
> a MUCH simpler and less morbid surgery than radical prostatectomy

Simpler, yes, but as long as the hole is already cut through the
abdominal muscle wall, what they do once inside isn't as critical to the
recovery morbidity. It was my right hemicolectomy that kept me in the
hospital the extra several days, and the hemicolectomy hole was much
bigger than an RRP hole. It was the hole in my abs that I felt for the
next 4-6 weeks,  not the traumatized prostate fossa. In my case, the uro
surgeon took a few hours to do his part, and the colon surgeon needed
only 20-30 minutes to do his. As you know and imply, the former is
rooting around in a tight space trying to distinguish and remove bad
meat from good meat, while the latter can essentially spread his work
out in front of himself and snip out fairly discrete parts. It does
leave me wondering, though, how easily they find dozens of lymph nodes.

My point is that since the greatest certain difference between RT and
RRP is in the short term -- the surgery recovery -- one would think that
having to get opened up anyway would probably swing the RP-RT dilemma
towards RP.

I.P.
Steph - 28 Feb 2006 19:30 GMT
>>>> I suspect that if he has colon and prostate cancer and no other mets,
>>>> they will cut out the colon tumor and radiate the prostate.
[quoted text clipped - 29 lines]
>
> I.P.

I'm not a surgeon, but I do know that the appropriate incision for a
colectomy is not the same as the incision for a prostatectomy. Only your
surgeons could answer whether the two procedures could (or should) be done
synchronously
I.P. Freely - 28 Feb 2006 22:24 GMT
> I'm not a surgeon, but I do know that the appropriate incision for a
> colectomy is not the same as the incision for a prostatectomy. Only your
> surgeons could answer whether the two procedures could (or should) be done
> synchronously

I wasn't speaking hypothetically. I had the R half of my colon and all
of my prostate removed in one surgery 16 months ago. My surgeons didn't
hesitate for a moment to agree to the dual procedure; ya just makes a
longer midline incision (my zipper is about 9" long), do the more
difficult or urgent surgery first, assess the pt, then do the second
procedure next. They even considered a third procedure in my case --
visual/ tactile/ pathological evaluation of my liver for carcinoid mets
-- but decided it wasn't sufficiently accessible to do more than a
cursory palpation. Several other tests had excluded liver involvement,
so they didn't bother to keep cutting.

I.P.
Steph - 01 Mar 2006 08:36 GMT
>> I'm not a surgeon, but I do know that the appropriate incision for a
>> colectomy is not the same as the incision for a prostatectomy. Only your
[quoted text clipped - 13 lines]
>
> I.P.

Only in the States!
I.P. Freely - 02 Mar 2006 03:23 GMT
>>> I'm not a surgeon, but I do know that the appropriate incision for a
>>> colectomy is not the same as the incision for a prostatectomy. Only your
[quoted text clipped - 14 lines]
>
> Only in the States!

Why is that? It seemed pretty logical to me, and when I suggested it to
the two surgeons (both oncs) their eyebrows shot up in approval (I think
I even saw enthusiasm for something new and different). I made sure the
surgeons had studied and planned their approach in detail and had passed
it by their oncology review board. Both procedures went by the book with
no surprises.

I.P.
Steph - 28 Feb 2006 01:51 GMT
>> "dave481" <daave481@yahoo.com> wrote in message
>> > Got back biopsies and they have Adenocarcinoma in all 12 samples (he
[quoted text clipped - 19 lines]
>
> How would they know, since they're both adenocarcinomas ?

Usually, prostate cancer cells will stain for psa, even if the blood test is
negative.

I don't recall the entire story here, but recurrent prostate cancer
presenting as a mass in the rectum is not uncommon.
I.P. Freely - 28 Feb 2006 07:21 GMT
 I believe they will
>> find that your tumor is a prostate cancer tumor in your colon as opposed to
>> colon cancer.
>
> How would they know, since they're both adenocarcinomas ?

PC is PC is PC. It's unmistakable (as PC) no matter where it occurs.

I.P.
Steph - 28 Feb 2006 08:17 GMT
>  I believe they will
>>> find that your tumor is a prostate cancer tumor in your colon as opposed
[quoted text clipped - 6 lines]
>
> I.P.

It's not quite that clear cut.
A poorly diff prostate cancer may be indistinguishable from a poorly diff
colon cancer, if they don't express PSA or CEA respectively
Steve Kramer - 28 Feb 2006 15:44 GMT
> A poorly diff prostate cancer may be indistinguishable from a poorly diff
> colon cancer, if they don't express PSA or CEA respectively

Mind you, I have not read this anywhere.  Nor would I have expected to.  The
discovery of the chromozomes in DNA particular to PCa is so new that the
writing of it has probably not extended to a dicsussion of determining
origin.  But, I would guess now that the chromozomes have been identified,
it should be a simple process to determine if the DNA taken from a mass is
PCa or CCa.
Steph - 28 Feb 2006 19:35 GMT
>> A poorly diff prostate cancer may be indistinguishable from a poorly diff
>> colon cancer, if they don't express PSA or CEA respectively
[quoted text clipped - 5 lines]
> it should be a simple process to determine if the DNA taken from a mass is
> PCa or CCa.

I'm a clinical oncologist, not a researcher, but this sound doubtful. Only a
very few rare conditions have specific chromosomes associated with the
disease. Chronic myeloid leukemia is the classic.
As far as I'm aware, prostate cancer does not.
Sure there may be specific gene expressions associated with prostate cancer,
and prostate cancers may have funny numbers of chromosomes, but that applies
to most cancers
Steve Kramer - 01 Mar 2006 07:37 GMT
>>> A poorly diff prostate cancer may be indistinguishable from a poorly
>>> diff colon cancer, if they don't express PSA or CEA respectively
[quoted text clipped - 9 lines]
> a very few rare conditions have specific chromosomes associated with the
> disease. Chronic myeloid leukemia is the classic.

Good!  You can take my idea and make $ Millions!

Just kidding.  It's nice to hear from someone with a working knowledge of
such things.  I hope Dave is listening.
I.P. Freely - 28 Feb 2006 17:36 GMT
>>  I believe they will
>>>> find that your tumor is a prostate cancer tumor in your colon as opposed
[quoted text clipped - 8 lines]
> A poorly diff prostate cancer may be indistinguishable from a poorly diff
> colon cancer, if they don't express PSA or CEA respectively

I gotcha; thanks for the clarification. So it's assessed by appearance,
which goes to hell as we near grade 5. I guess the next issue is which
type of CC is involved. Carcinoid CC is pretty unique in its production
of 5-HIAA, I believe, and thus more distinguishable from even a grade 5 PC.

I.P.
Steph - 28 Feb 2006 19:32 GMT
>>>  I believe they will
>>>>> find that your tumor is a prostate cancer tumor in your colon as
[quoted text clipped - 14 lines]
>
> I.P.

Carcinoid is a rare colon cancer. 99% of colon cancers are plain old colonic
adenoca. CArcinoid does look different histologically, and I doubt many
pathologists would confuse them
I.P. Freely - 28 Feb 2006 22:10 GMT
> Carcinoid is a rare colon cancer. 99% of colon cancers are plain old colonic
> adenoca. CArcinoid does look different histologically, and I doubt many
> pathologists would confuse them

Tell me about it ... then calculate the odds one active and
healthy-eating person is going to encounter a large and rapidly-growing
carcinoid colon tumor with no mets or symptoms, Gleason 8 PC which saved
his life, and a labyrinthectomy due to Meniere's disease?

I musta PO'd some god somewhere along the line. I hope he's retired
before I try to skate past a reoccurrence.

I.P.
I.P. Freely - 28 Feb 2006 00:25 GMT
> Got back biopsies and they have Adenocarcinoma in all 12 samples (he
> took 14, don't know what happen to the other 2). Anyhow, on the Gleason
[quoted text clipped - 10 lines]
> sure have enjoyed the feedback here. Oh, and. Can you ride a horses
> after prostate removal? Or is the pain too great?

The next day? NO! 6-8 weeks post-RRP you can ride a bull (presuming you
can ride one now and you stay in shape).

There are widely different types of colon cancer on the menu. A LOT
depends on the type and the location. Find out what kind and location
you have and start Googling it.

Gleason grading is quite reliable, in that very professional second
opinions are readily available. I'd want a large national lab to grade
mine, but you may know much more after tomorrow's scan than a second
Gleason grading can tell you.

I.P.
juniper - 28 Feb 2006 03:41 GMT
> Got back biopsies and they have Adenocarcinoma in all 12 samples (he
> took 14, don't know what happen to the other 2). Anyhow, on the Gleason
> scale I had one-7, two-8s, six-9s, and two -10s. The uro said that is
                   Pretty harsh, Dave, I'm sorry.
> imaging center for a CT of abdomen and pelvic. Then to the nuclear part
> of that place for a bone scan. This all came about because of a
                   Nice you're getting so much done so fast.  This
will all help.
> all the Drs. will be putting their heads together to form a battle plan
                   So cool you have a good team that works together.
> of cancer you can share? Or the reliabilty of the Gleason scale?  I
                   Well, the Gleason is pretty predictive.  Everyone
was sorry we had a 7.
> sure have enjoyed the feedback here. Oh, and. Can you ride a horses
                   Having had a couple of abdominal surgeries, you can
do anything after a couple of months.   One time I was living on a mine
in the desert.  I think the minimum slope to the mountainside I lived
on was about 6/1.  I wasn't doing anything but falling into bed,
because except for the 30 or so square feet of our travel trailer,
everything was too hard to climb up.  Getting to the outhouse was pure
hell.  I finally gave up and went to my family's for a couple of weeks.
Fixed me right up, being able to walk on normal ground.

> p.s. this is such an "indignant" disease.
                     How dare it!

regards, and good luck with your scans.

laurel
Jim - 28 Feb 2006 04:01 GMT
>Got back biopsies and they have Adenocarcinoma in all 12 samples (he
>took 14, don't know what happen to the other 2). Anyhow, on the Gleason
[quoted text clipped - 14 lines]
>
>p.s. this is such an "indignant" disease.

David
Sorry to hear about your findings.  You didn't mention your PSA.

I was diagnosed last March with advanced PCA.  It had spread to the
spine, hips legs, ribs.  etc.  
I'll be surprised if your bone scan doesn't show metastatic spots.
If yours has spread, as I expect it has, they will not remove the
prostate.  The operation would be a failure going in.

They treated me with total androgen blocade using Zoladex and Casodex.
I got monthly injections of Zometa to help the bones heal.
My psa plumeted from 725.4 to 6.6 in 4 months and I was feeling fine..
Unfortunately it started going back up after that.  That showed that
the cancer had become resistant to the hormones.
I was then given a series of 4 treatments with Taxotere, a chemo
agent.  The psa came down to 9.9.  The treatment was stopped.
Within a month the pas was up to 25.6.  They won't put me back on
Taxotere because the tumor is resistant to it and the doctor said that
he doesn't want to expose me to the toxicity of it needlessly.
I'm now getting a series of 8 treatments of Navelbine.

I had hoped that the hormones would work for 5-10 years before failure
which is common.  My thinking was that there is a chance that a "cure"
could be found by then.  Didn't happen.  Hopefully you will have
better results than I've had up to now.  
Jim
 
dave481 - 28 Feb 2006 09:07 GMT
Jim, it's 03:00 am and anxiety woke me up. Yours is the first post I've
read here where they didn't remove something. a psa higher than mine
(36.8), way higher and it sure doesn't sound like much fun. I haven't
had the scans yet, so don't really know anything. I didn't know they
treated things this way. Thank-you and all who have responded.
God Bless
David
Steve Kramer - 28 Feb 2006 15:37 GMT
Sorry, Dave!  I am sure that I am one of those to whom you refer as having
added to your anxiety level.  I don't remember how old you are, if you told
us, but if this is your foray into major surgery, radiation, hormone
treatment and/or chemotherapy, it is rather daunting.  And, at Ages 46, 47
and 48 it was to me.  I interact so often now with those here that have been
through it, that I forget how daunting it is to those who have not.  So let
me be specific about these so that you can know and understand.  I will list
for you the hardest things to go through and in order:

STRUGGLING WITH YOUR MORTALITY.  I list this without a number, because it is
different in every man.  And each man has a different view of it depending
on his age, environment, situation and other issues that uniquely come into
play.  Personally, for example, my father died of PCa at 50.  So, I almost
expected it.  My children were grown and clearly on the right paths.  I can
retire anytime I want and provide for my wife.  So, mortality is not at the
top of my list.  But, it is most assuredly at the top of others'.

1.  TELLING YOUR LOVED ONES.  I swear to God, I hate this one.  I wish I
could have been like my grandfather who passed out in his backyard and died
on the operating table as they were trying to remove the tumor that had
wrapped itself around his vertebrae.  He must have been in serious pain, but
no one in the family knew, because, I assume, he couldn't bear to tell
anyone.

2.  BONE PAIN.  I haven't experienced it, but I've heard descriptions of it
and it must have just been gawd-awful.  Fortunately, now, while it's still
extremely painful, there are medications that do a good job of lessening it.
My dad's pain was so great that they had to practically put him into a coma
with Morphine.

3.  CHEMOTHERAPY.  This stuff makes you really sick.  It made my dad so sick
that I swore, when I watched him die, that I would never fight as hard as he
did.  However, again, the treatments of today are much better that in the
late 70s, so I think I'll fight the bastard to the end.

4.  HORMONE THERAPY.  The treatment itself is painless.  A shot in the a.s 
and you're done.  Sometimes the nurse says, "Hold on.  I'm going to put a
Band-Aid on it" before I realize I had the shot.  But the side effects are
moderate to severe.  I suffer from memory lapses, fatigue, weight gain, and
I read the articles in Playboy.

5.  DIAGNOSTIC SCANS.  I hate laying on a table absolutely still and one
required I do so for 2 hours!

6.  SURGERY.  The hardest part of surgery for me was my family parading
through pre-op and crying about my 'certain death.'  For the rest of it, I
was asleep.  When I awoke, I had a team of nurses to care for my every need.
I went home and laid around for a few weeks until I begged the doctor to let
me go back to work.

7.  RADIATION.  You go lay down on a table and a giant dentist's X-ray cone
moves around you.  The side effects, especially if you prepare yourself with
hydration, exercise and sleep are mild and temporary.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) @ 48, 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05,
10/05, 2/06
PSA  .07 .05 .06 .09 .08 .132
Non Illegitimi Carborundum

> Jim, it's 03:00 am and anxiety woke me up. Yours is the first post I've
> read here where they didn't remove something. a psa higher than mine
[quoted text clipped - 3 lines]
> God Bless
> David
I.P. Freely - 28 Feb 2006 18:34 GMT
> 2.  BONE PAIN.  I haven't experienced it, but I've heard descriptions of it
> and it must have just been gawd-awful.  Fortunately, now, while it's still
[quoted text clipped - 6 lines]
> did.  However, again, the treatments of today are much better that in the
> late 70s, so I think I'll fight the bastard to the end.

I'm already fighting that stage of the bastard: I've offered motivation
and help to my state legislators towards passage of our assisted suicide
bill. Forcing a clearly terminal pt and family to endure weeks to months
of comatose agony just to satisfy religious zealots and hippocratic
oaths is unconscionable.

I.P.
Claude - 28 Feb 2006 21:59 GMT
>> 2.  BONE PAIN.  I haven't experienced it, but I've heard descriptions of
>> it and it must have just been gawd-awful.  Fortunately, now, while it's
[quoted text clipped - 14 lines]
>
> I.P.

Treading gingerly into an issue that may have political ramifications---but
here we agree---and this is definitely disease related---an even more
important battle to fight is to get the DEA off the backs of physicians so
that they are not afraid to prescribe adequate pain meds.  As far as I'm
concerned, if I have terminal cancer, give me all the meds I need to control
the pain, and if I OD, so be it.
I.P. Freely - 28 Feb 2006 22:57 GMT
> Treading gingerly into an issue that may have political ramifications---but
> here we agree---and this is definitely disease related---an even more
> important battle to fight is to get the DEA off the backs of physicians so
> that they are not afraid to prescribe adequate pain meds.  As far as I'm
> concerned, if I have terminal cancer, give me all the meds I need to control
> the pain, and if I OD, so be it.

The courts shot down our federal (Ashcroft's) attempt to prohibit
assisted suicide; now it's going to be state by state. At last count
only one U.S. state allows it. Conveniently for me, that state is just
20 minutes away. HOWEVER ... if my state (or the docs' fear of the
courts) won't provide relief when relief is all that's left, there are
other, more graphic, solutions that may help not only me but others in
similar sinking ships.

I.P.
Steve Kramer - 01 Mar 2006 07:53 GMT
>> Treading gingerly into an issue that may have political
>> ramifications---but here we agree---and this is definitely disease
[quoted text clipped - 8 lines]
> relief when relief is all that's left, there are other, more graphic,
> solutions that may help not only me but others in similar sinking ships.

Might I recommend something in a size 12?
I.P. Freely - 02 Mar 2006 03:16 GMT
>>  At last count only one U.S.
>> state allows it. Conveniently for me, that state is just 20 minutes away.
[quoted text clipped - 3 lines]
>
> Might I recommend something in a size 12?

If you're referring to shoes for hiking the 25 miles, that would solve
MY problem, but maybe some publicity and a well-researched,
well-explained public appeal for legislation would solve MANY people's
problems.

If you were referring to a GAUGE 12 ... now we're on the same page. It
would make two points:
1. If a pregnant woman's body is her own, so is mine.
2. If the legislation were in place, I could have lived a few more weeks
or months without risking becoming too feeble to take care of business
and you wouldn't have this mess all over everything.

I.P.
Steve Kramer - 02 Mar 2006 07:13 GMT
>> Might I recommend something in a size 12?
>
> If you were referring to a GAUGE 12 ... now we're on the same page.

I was and we are.
doubleowseven@theplacecalledyahoo.com - 04 Mar 2006 04:22 GMT
>>> Might I recommend something in a size 12?
>>
>> If you were referring to a GAUGE 12 ... now we're on the same page.
>
>I was and we are.

A running car in a closed garage is less traumatic to the "patient".
And no legislation needed.  Probably less traumatic too to those left
behind who will have to deal with the results of a 12 gauge.
I.P. Freely - 04 Mar 2006 06:42 GMT
> A running car in a closed garage is less traumatic to the "patient".
> And no legislation needed.  Probably less traumatic too to those left
> behind who will have to deal with the results of a 12 gauge.

But which gets more press and thus brings more attention to the plight
of others in the same sinking boat?

Oh, well ... with any luck it won't come to that, and I'll die in my 90s
'cause my bungee cord was five feet too long.   ;-)

I.P.
Steve Kramer - 04 Mar 2006 13:52 GMT
> A running car in a closed garage is less traumatic to the "patient".
> And no legislation needed.  Probably less traumatic too to those left
> behind who will have to deal with the results of a 12 gauge.

I don't want to turn this into a suicide site, so I won't give any more
details or attributes.

Conversely, if anyone does take any course of action, I recommend that their
first consideration be a plan to do it where no one in the family will have
to deal with it.  Why a father and/or husband would shoot himself in a home,
or hang himself in the backyard or closet where there is a 50/50 chance or
greater his child will find him and 100% chance someone in his family will,
is beyond me.  That goes for the garage as well.  If you're going to do it,
go down to the morgue, knock on the door and let the attendant find you.
I.P. Freely - 05 Mar 2006 00:35 GMT
>> A running car in a closed garage is less traumatic to the "patient".
>> And no legislation needed.  Probably less traumatic too to those left
[quoted text clipped - 10 lines]
> is beyond me.  That goes for the garage as well.  If you're going to do it,
> go down to the morgue, knock on the door and let the attendant find you.

My thought was to call in the press, read a prepared statement if I was
still able (or play a tape if no longer able to speak), discuss the need
for carefully controlled assisted suicide legislation, then demonstrate
the only alternative we have now to avoid the intractable,
dysfunctional, excruciating, incommunicative end to so many diseases.
Anything from a stick of dynamite to a quick-acting pill would make the
point, depending on how dramatic one felt the point need be made.

Even if a pt chose to fight for every last breath for whatever reason,
the knowledge that his form and time of demise is HIS CHOICE would give
most pts a degree of control most pts don't have now, and I'm guessing
that would be extremely important to a terminal pt.

Then there's the family. Alzheimer's, I gather, is hard only on the
family once it is all that's  left. Why on earth would I want my wife to
have to deal for years with a blathering idiot who doesn't even
recognize her anymore?

I.P.
Steve Kramer - 05 Mar 2006 00:53 GMT
> Why on earth would I want my wife to have to deal for years with a
> blathering idiot who doesn't even recognize her anymore?

As opposed to one who does?    ;-)
Heather - 05 Mar 2006 02:05 GMT
>> Why on earth would I want my wife to have to deal for years with a
>> blathering idiot who doesn't even recognize her anymore?
>
> As opposed to one who does?    ;-)

Touché, puss....that got me giggling!!
juniper - 02 Mar 2006 02:27 GMT
Well, IP, considering the state of your health, the 'other, more
graphic solutions' would be decades away.  But we can always count on
you to think things through ahead of time.
> The courts shot down our federal (Ashcroft's) attempt to prohibit
> assisted suicide; now it's going to be state by state. At last count
[quoted text clipped - 5 lines]
>
> I.P.
I.P. Freely - 02 Mar 2006 03:30 GMT
> Well, IP, considering the state of your health, the 'other, more
> graphic solutions' would be decades away.  But we can always count on
> you to think things through ahead of time.

The statistics of EACH of my cancers by itself gives me less than a
50/50 shot at 10 years. Combining the stats gives me much less. But they
both also leave wiggle room around the ends of their curves, so I'm
wiggling like a golden retriever puppy in the meantime.

I.P.
Steve Kramer - 01 Mar 2006 07:49 GMT
>> 2.  BONE PAIN.  I haven't experienced it, but I've heard descriptions of
>> it and it must have just been gawd-awful.  Fortunately, now, while it's
[quoted text clipped - 12 lines]
> of comatose agony just to satisfy religious zealots and hippocratic oaths
> is unconscionable.

I agree with the Hippocratic Oath.  An oath to Hippocrates regarding the
treatment of humans that is violated from the very first time they accept a
dollar for their services is hypocritical.

But religious zealots?  Why do they have to be zealots?  Can't they just be
believers?  Does one have be a zealot to believe in God and in His Word?

However, I also agree with you that suicide should not be legislated, and it
is unconstitutional for the federal government to do so.  Suicide is between
a man and himself if he does not believe and a man and God if he does.
Steve Jordan - 01 Mar 2006 17:57 GMT
On March 1, Steve Kramer replied to IP:
> I agree with the Hippocratic Oath. An oath to Hippocrates regarding the
> treatment of humans that is violated from the very first time they accept a
[quoted text clipped - 7 lines]
> a man and himself if he does not believe and a man and God if he does.
>  
And from a philosophical, even practical, viewpoint:

"...the sole end for which mankind are warranted, individually or
collectively, in interfering with the liberty of action of any of their
number, is self-protection. The only purpose for which power can be
rightfully exercised over any member of a civilised community, against
his will, is to prevent harm to others. His own good, either physical or
moral, is not sufficient warrant. He cannot rightfully be compelled to
do or forbear because it will be better for him to do so, because it
will make him happier, because, in the opinion of others, to do so would
be wise, or even right...The only part of the conduct of anyone, for
which he is amenable to society, is that which concerns others. In the
part which merely concerns himself, his independence is, of right,
absolute. Over himself, over his own body and mind, the individual is
sovereign."
-John Stuart Mill

Regards,

Steve J

>  
Steve Kramer - 01 Mar 2006 18:19 GMT
> "...the sole end for which mankind are warranted, individually or
> collectively, in interfering with the liberty of action of any of their
[quoted text clipped - 9 lines]
> himself, over his own body and mind, the individual is sovereign."
> -John Stuart Mill

I dont' know who Mr. Mill is, but wherein suicide and civil legislation is
concerned, I cannot find fault with his opinion.
Steve Jordan - 01 Mar 2006 20:08 GMT
On March 1, Steve Kramer responded to my John Stuart Mill quotation:
> I dont' know who Mr. Mill is, but wherein suicide and civil
> legislation is
> concerned, I cannot find fault with his opinion.
>  
John Stuart Mill (1806-1873) was a leading social and political
philosopher in Great Britain.

More can be found at: http://www.utm.edu/research/iep/m/milljs.htm

Regards,

Steve J

Another Mill quotation:

"War is an ugly thing, but not the ugliest of things.  The decayed and
degraded state of moral and patriotic feeling that thinks that nothing
is worth war is much worse.  The person who has nothing for which he is
willing to fight, nothing which is more important than his own personal
safety, is a miserable creature and has no chance of being free unless
made and kept so by the exertions of better men than himself."

>  
Alex - 01 Mar 2006 21:20 GMT
[ snip ]

> But religious zealots?  Why do they have to be zealots?  Can't they just
> be believers?  Does one have be a zealot to believe in God and in His
> Word?

Hey, I'm OK with the idea that God exists. But I draw the line at the notion
of "intelligent design," if the prostate gland is an example of His
handiwork. (g)

Alex
Steve Kramer - 02 Mar 2006 07:09 GMT
> [ snip ]
>>
[quoted text clipped - 5 lines]
> notion of "intelligent design," if the prostate gland is an example of His
> handiwork. (g)

He said no one will live beyond 120.  Do  you know any 119 year old males
who do not have prostate cancer.  He built in obsolescence, that's all.
:-)
I.P. Freely - 02 Mar 2006 03:03 GMT
> But religious zealots?  Why do they have to be zealots?  Can't they just be
> believers?  Does one have be a zealot to believe in God and in His Word?

Would a "mere" believer raise hell, even take action, if a terminal
stranger in extreme circumstances wanted to end his suffering?

I.P.
Steve Kramer - 02 Mar 2006 07:10 GMT
>> But religious zealots?  Why do they have to be zealots?  Can't they just
>> be believers?  Does one have be a zealot to believe in God and in His
>> Word?
>
> Would a "mere" believer raise hell, even take action, if a terminal
> stranger in extreme circumstances wanted to end his suffering?

No.  And I've never understood those who do.  Even Jesus Christ did not.
I.P. Freely - 02 Mar 2006 20:16 GMT
>>> But religious zealots?  Why do they have to be zealots?  Can't they just
>>> be believers?  Does one have be a zealot to believe in God and in His
[quoted text clipped - 3 lines]
>
> No.  And I've never understood those who do.  Even Jesus Christ did not.

That's why I added the Z word.

I.P.
Steve Kramer - 02 Mar 2006 21:47 GMT
>>>> But religious zealots?  Why do they have to be zealots?  Can't they
>>>> just be believers?  Does one have be a zealot to believe in God and in
[quoted text clipped - 4 lines]
>> No.  And I've never understood those who do.  Even Jesus Christ did not.
> That's why I added the Z word.

So, you think the laws are based on zealousness and not belief.  I can
accept that.
doubleowseven@theplacecalledyahoo.com - 04 Mar 2006 04:26 GMT
>>>>> But religious zealots?  Why do they have to be zealots?  Can't they
>>>>> just be believers?  Does one have be a zealot to believe in God and in
[quoted text clipped - 7 lines]
>So, you think the laws are based on zealousness and not belief.  I can
>accept that.

I think they are based on both since there would not be such laws
against suicide for the terminally ill unless those passing them both
believed it was wrong and were sufficiently zealous in their belief to
work for years to get such laws in place.  Same is true for the
anti-choice for abortion, they are both zealots and believers.
Steve Kramer - 04 Mar 2006 14:09 GMT
> I think they are based on both since there would not be such laws
> against suicide for the terminally ill unless those passing them both
> believed it was wrong and were sufficiently zealous in their belief to
> work for years to get such laws in place.  Same is true for the
> anti-choice for abortion, they are both zealots and believers.

I think they are based on a common foundation of what every non-psychotic
knows as being either right or wrong.  For a couple of millennia, this
common knowledge was sufficient for a majority of a population to understand
that a breach of them would result in quick and sure punishment (except west
of the Pecos).

Now, a number of people, almost undoubtedly a minority, are sufficiently
screwed up in their thinking that they have determined that a bastardization
of these commonly agreed upon tenets are in order.  It is better for them,
or easier for them, and, irregardless of the effect on society, community,
neighborhood or family they desire a change.  When they don't get their
change or someone debates their "need" for such, somehow those who concur
with the status quo are labeled as zealots.

I think laws based on principles are much better than laws based on a lack
thereof.
Steve Kramer - 28 Feb 2006 15:07 GMT
I'm sorry to hear that Jim.  Last I knew, you were looking at no further
treatment if your PSA was less than 10 (after  your Decemeber treatment).  I
imagine you were preetty happy with the 9.9, and pretty pissed at the 25.6.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06
PSA  .07 .05 .06 .09 .08 .132
Non Illegitimi Carborundum

>>Got back biopsies and they have Adenocarcinoma in all 12 samples (he
>>took 14, don't know what happen to the other 2). Anyhow, on the Gleason
[quoted text clipped - 41 lines]
> better results than I've had up to now.
> Jim
juniper - 28 Feb 2006 05:07 GMT
> Got back biopsies and they have Adenocarcinoma in all 12 samples (he
> took 14, don't know what happen to the other 2). Anyhow, on the Gleason
> scale I had one-7, two-8s, six-9s, and two -10s. The uro said that is
                   Pretty harsh, Dave, I'm sorry.
> imaging center for a CT of abdomen and pelvic. Then to the nuclear part
> of that place for a bone scan. This all came about because of a
                   Nice you're getting so much done so fast.  This
will all help.
> all the Drs. will be putting their heads together to form a battle plan
                   So cool you have a good team that works together.
> of cancer you can share? Or the reliabilty of the Gleason scale?  I
                   Well, the Gleason is pretty predictive.  Everyone
was sorry we had a 7.
> sure have enjoyed the feedback here. Oh, and. Can you ride a horses
                   Having had a couple of abdominal surgeries, you can
do anything after a couple of months.   One time I was living on a mine
in the desert.  I think the minimum slope to the mountainside I lived
on was about 6/1.  I wasn't doing anything but falling into bed,
because except for the 30 or so square feet of our travel trailer,
everything was too hard to climb up.  Getting to the outhouse was pure
hell.  I finally gave up and went to my family's for a couple of weeks.
Fixed me right up, being able to walk on normal ground.

> p.s. this is such an "indignant" disease.
                     How dare it!

regards, and good luck with your scans.

laurel
juniper - 03 Mar 2006 04:39 GMT
Dave, let us know what your scans show.  I'll be hanging out at a
hospital and doubt I'll have much Internet access, but I'll try to keep
up.  Thinking of you.

> Got back biopsies and they have Adenocarcinoma in all 12 samples (he
> took 14, don't know what happen to the other 2). Anyhow, on the Gleason
[quoted text clipped - 14 lines]
>
> p.s. this is such an "indignant" disease.
dave481 - 03 Mar 2006 04:54 GMT
laurel, the scans came back neg. Very grateful, you and Steve hang in
there. I'm praying for you monday. They take out my prostate thurs. the
9th. And the colon cancer as well. Stay in touch
God Bless you
David
J - 03 Mar 2006 11:29 GMT
> laurel, the scans came back neg. Very grateful, you and Steve hang in
> there. I'm praying for you monday. They take out my prostate thurs. the
> 9th. And the colon cancer as well. Stay in touch
> God Bless you
> David

David,
way back iin the thread, Steph mentioned CEA.
Do make sure that's tested. It may be of no significance if the surgery
cures the colon cancer.
If surgery doesn't cure the colon cancer, it's (later) used as a
(treatment) monitoring marker.
So it's important to know if yours expresses CEA. If it does, it'll likely
drop after the surgery, so have it tested before.
Is my non-expert understanding.
J
juniper - 04 Mar 2006 01:38 GMT
> laurel, the scans came back neg. Very grateful, you and Steve hang in
> there. I'm praying for you monday. They take out my prostate thurs. the
> 9th. And the colon cancer as well. Stay in touch
> God Bless you
> David

YES!!!  So that back pain is arthritis, huh?  Too many broncs in your
youth....  Maybe its smashed discs.  Yuck.  Why do I think like this?

I am so happy for you Dave.  This is GREAT.  And good luck to you also!
 
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