Hi Guys:
As some of you know my RP was a "biochemical failure" as I have a
detectable psa (stats below).
Rad onc & surgeon recommend radiation. I have family vacation planned
mid-April. Do you think it would be fool hardy to go then start
treatment when I return? Or should I just tackle this beast and pass on
joining my family this round? Rad Onc is saying not certain that this
is localized but my best hope for knoocking this thing out. Getting
opinions from med onc's this week.
What would you do?
6/03 - PSA 2.0
6/04 - PSA 2.5
8/05 - PSA 4.2
Normal CAT, Bone
11/05 - PSA 5.89
BIOPSY 8/16/05
T2A, 3+5 = 8
RP 12/13/05
PATHOLOGY GLEASON 3+5=8
TERTIARY 4, SEMINAL & LYMPH - NEG
T2A, EXTRACAPSULAR EXTENSION UPTO MARGIN
PSA POST RP 1/26/06 = 0.5, 2/1/06 = 0.55
I.P. Freely - 27 Feb 2006 05:25 GMT
> Hi Guys:
>
[quoted text clipped - 8 lines]
>
> What would you do?
I'd ask 'em for more ideas on determining whether it's localized, vacation
or no vacation, before I accepted additional treatment. Newer diagnostic
tools such as the combined CT/PET scan, for example, may miss small mets and
may not even work all that well with PC, but if it FINDS a met, that pretty
much rules out standard RT. Any PC test can produce false negatives, but if
one returns a positive for remote mets, I'd sure rethink that RT.
As for the vacation, I'd have to take my docs' word on the degree of
urgency, along with maybe a second or third opinion.
As for the med onc's opinion ... make sure s/he discusses its benefits and
SEs to the nth degree, and add your own research. That's serious stuff
compared to simple old crotch radiation.
I.P.
Steve Kramer - 27 Feb 2006 11:27 GMT
Dominic,
My RT history:
12/2000 -- My surgery
12/2001 -- First rise above virtually undetectable
03/2002 -- Second rise
05/2002 -- Third rise
Later that month -- Radiation treatment.
I think you have time to spend with your family.

Signature
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA .1 .1 .1 .27 .37 .75
EBRT 05-07/2002 @ 47
PSA .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05,
2/06
PSA .07 .05 .06 .09 .08 .132
Non Illegitimi Carborundum
> Hi Guys:
>
[quoted text clipped - 21 lines]
> T2A, EXTRACAPSULAR EXTENSION UPTO MARGIN
> PSA POST RP 1/26/06 = 0.5, 2/1/06 = 0.55
Leonard Evens - 27 Feb 2006 16:21 GMT
> Hi Guys:
>
[quoted text clipped - 21 lines]
> T2A, EXTRACAPSULAR EXTENSION UPTO MARGIN
> PSA POST RP 1/26/06 = 0.5, 2/1/06 = 0.55
This is really someting you have to explore with your doctors. If you
aren't convinced by what they tell you, try to get other medical opinions.
I am not a doctor. My uneducated guess is that since the initial PSA
after surgery was so high, and since the cancer extended right up to the
margin, it is reasonable to suppose that some cancer extended beyond the
margin and was not removed. In that case, local radiation could cure
it. On the other hand, the Gleason 8 increases the likelihood that the
cancer had already spread to distant sites. If I were in your
situation and my doctors recommended radiation, I would follow their
recommendations.
Tom - 27 Feb 2006 20:35 GMT
Don't know about NZ, but I've been to many other places in the world and
our TSA and
other place, if they even look in your carry on bag, have no problem
with any meds if
you have them in the original container with the prescrition and docs
name, 'scrip number, etc.
Tom
> Hi Guys:
>
> As some of you know my RP was a "biochemical failure" as I have a
> detectable psa (stats below).
> Rad onc & surgeon recommend radiation. I have family vacation planned
<snip>
Pops - 28 Feb 2006 14:54 GMT
DominicM
Just me, and from very-much layman's point fo view.
I'd get at it! I know that PCa is slow growing and all that jazz. But
to me,an engineer, time = spread. The quicker you get at it the less
chance it has spread. To me it's that simple.
I had a 0.24 reading 4 months post LRP and then a second at 5 months of
0.12. I went immediately to prep for radiation. Turned out to be a
"false alarm" (I hope) since my PSA has been less than 0.1 ever since,
but I was ready and willing.
My approach is based on the fact that radiation is my last curative
option. I would have just the opposite approach should radiation fail
and I had to face hormone therapy. I would put that off until proof of
mets occurred and then would think long and hard about whether to have
the treatment at all. It's not curative, and it can have some ugly side
effects. We've all got to die someday. Quality of life, as opposed to
length of life, is most important to me. I like to be in the driver's
seat. Just Me!
Best of luck to you. Keep the faith!
DominicM - 02 Mar 2006 01:26 GMT
Thanks for everyone's input. I am 99% sure based on recommendation of
surgeon, radiologist and two med onc's (Sloan & Hopkins) that I go
forward with
SRT asap. I'll let the wife and kids vacation while I try to kill this
beast while I can. Med Onc don't think I need to start hormone
treatment unless SRT fails.
I had one positive margin (extracap extension) so that make me a better
candidate despite high velocity (but still low psa) and Gleason 8.
DominicM - 02 Mar 2006 01:45 GMT
Thanks for everyone's input. I am 99% sure based on recommendation of
my
surgeon, one radiologist and two med onc's (Sloan & Hopkins) that I'll
go
forward with SRT asap.
I'll let the wife and kids vacation while I try to kill this beast
while I can. Med Onc's don't think
I need to start hormone treatment unless SRT fails. I'm not inclined to
complicate matters more
at this point. I had one positive margin (extracap extension - right
apex) so that makes me a better
candidate despite high velocity psa (but still low) and Gleason 8.
DominicM - 02 Mar 2006 01:45 GMT
Thanks for everyone's input. I am 99% sure based on recommendation of
my
surgeon, one radiologist and two med onc's (Sloan & Hopkins) that I'll
go
forward with SRT asap.
I'll let the wife and kids vacation while I try to kill this beast
while I can. Med Onc's don't think
I need to start hormone treatment unless SRT fails. I'm not inclined to
complicate matters more
at this point. I had one positive margin (extracap extension - right
apex) so that makes me a better
candidate despite high velocity psa (but still low) and Gleason 8.