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Medical Forum / Diseases and Disorders / Prostate Cancer / January 2006Data for Steve
Steve, Thought I'd pass along some additional PSA history for your records: 04/11/05 - 0.3 06/07/05 - 0.2 08/06/05 - 0.4 09/17/05 - 1.7 10/01/05 - 1.9 (Casodex Withdrawal) 10/15/05 - 1.8 10/29/05 - 1.8 11/14/05 - 1.8 12/01/05 - 1.7 12/16/05 - 1.6 01/03/06 - 1.7 01/23/06 - 0.8 So far, I have fallen in the 20% group that shows a PSA drop when Casodex is withdrawn and clears the body. Scans are clear with new bone growth complete where the two mets were. 24 year stats from my Medical Oncologist after Casodex Withdrawl are: Shortest time of continued PSA drop - 4 weeks Longest time of continued PSA drop - 15 months Still a waiting game, but with many more bullets in the arsenal...... Mike Hi, Gourd, I'm confused. You had a chemo trial that ended in December 2004. Your PSA was below 1.0 until it rose signficantly in September 2005. And then it started sneaking back down? Is that what is expected? Was there any additional treatment in or since September? You certainly aren't sitting still for cancer. You have to be near half a dozen different treatments.  SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05 PSA .07 .05 .06 .05 .08 Non Illegitimi Carborundum > Steve, Thought I'd pass along some additional PSA history for your > records: [quoted text clipped - 23 lines] > > Mike Steve and Gourd, I finished my 2 year trial and also experienced at slight bump in numbers - 0.003 Sep05 0.014 Oct 05 0.025 Nov 05 0.004 Jan 06 I'd never heard of the Casodex w/drawal bump - but I'm glad to see I'm not the only one. DanR > Hi, Gourd, > [quoted text clipped - 7 lines] > You certainly aren't sitting still for cancer. You have to be near half a > dozen different treatments. Them are some great numbers, Dan. Sounds like a success. SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05 PSA .07 .05 .06 .05 .08 Non Illegitimi Carborundum > Steve and Gourd, > I finished my 2 year trial and also experienced at slight bump in [quoted text clipped - 19 lines] >> You certainly aren't sitting still for cancer. You have to be near half >> a dozen different treatments. Dan Great numbers, keep at it! Mike > Steve and Gourd, > I finished my 2 year trial and also experienced at slight bump in [quoted text clipped - 19 lines] >> You certainly aren't sitting still for cancer. You have to be near half >> a dozen different treatments. Thanks Mike and Steve. I was a "bit" cncerned near the end of November....but am able to breathe again! low numbers to all. DanR > Dan Great numbers, keep at it! > [quoted text clipped - 23 lines] >>>You certainly aren't sitting still for cancer. You have to be near half >>>a dozen different treatments. Steve, That's right. After the Chemo ended in December 2004, the balance of the two year trial was to start 50 mg of Casodex a day. Under normal circumstances one would expect the PSA to stay down 18-24 months. In my case it started rising at 9 months. At that point I came off of Casodex. Researchers have known since 1995 that after the stoppage of Casodex, PSA drops in 20% of the cases. I fell into that 20% group and the PSA dropped once the half-life of Casodex cleared by body. It is expected that PSA will stay down anywhere from 4 to 15 months. As long as the PSA stays down, I win. As soon as it starts to rise, it is time for another bullet so that the cancer does not become strong enough to take over. Belief is that some where in my body a micro-fiber of cancer is floating around, missed by the Chemo, just waiting for a place to land and attach itself and grow. The nest way to monitor is via PSA and CEA tests. PSA draw is now at once a month and CEA to monitor genetic change at once every four months along with Bone Scan, Chest X-ray, and CT Scan. I have taken a very aggressive attitude towards an aggressive cancer. It's a waiting game and I would rather fight in Phase II trials than wait on the FDA. You might think of it as instead of Non Illegitimi Carbordum, I prefer to Knock the Bastard Down .... and as fast as I can. I'll keep you informed on ammo used in the arsenal when it becomes necessary. :) Mike > Hi, Gourd, > [quoted text clipped - 35 lines] >> >> Mike > You might think of it as instead of Non Illegitimi Carbordum, I prefer to > Knock the Bastard Down .... and as fast as I can. Sounds much better. I wish I knew more Latin than what I learned as an alter boy. SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05 PSA .07 .05 .06 .05 .08 Non Illegitimi Carborundum
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