Three years age I had a PSA value of 12.4 and prostate cancer was confirmed
by a biopsy. The doctor started me on a hormone therapy medication called
"Cosudex".
As a result of either the biopsy or the hormones or both, my penis shortened
in length by over one inch. When I mentioned this to my doctor he found it
quite amusing. I didn't. I wasn't all that well endowed to begin with. The
problem has persisted ever since. I sent an e-mail to the cancer foundation
of Australia and they said they had never heard of it before. Another brush
off.
Has anyone else got this problem, or a solution?
Adam.
Steve Kramer - 20 Jan 2006 22:22 GMT
> Three years age I had a PSA value of 12.4 and prostate cancer was
> confirmed by a biopsy. The doctor started me on a hormone therapy
[quoted text clipped - 7 lines]
> Has anyone else got this problem, or a solution?
> Adam.
I am not sure why they would have put you on hormone treatment without
surgery or radiation. However, I cannot thing of any reason your penis
would shorten. Mine did with surgery, but hormones? Don't make sense.

Signature
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA .1 .1 .1 .27 .37 .75
EBRT 05-07/2002 @ 47
PSA .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05
PSA .07 .05 .06 .05 .08
Non Illegitimi Carborundum
Steve U - 20 Jan 2006 23:04 GMT
Adam,
Your doctor sounds like an uncompassionate jerk. Maybe you should find
someone who does not find the problem amusing.
Steve U
Steve Jordan - 20 Jan 2006 23:24 GMT
> Three years age I had a PSA value of 12.4 and prostate cancer was confirmed
> by a biopsy. The doctor started me on a hormone therapy medication called
> "Cosudex".
>
Correction: Casodex. Look it up on http://www.rxlist.com/ for details.
> As a result of either the biopsy or the hormones or both, my penis shortened
> in length by over one inch. When I mentioned this to my doctor he found it
[quoted text clipped - 3 lines]
> off.
>
Very much my story, except that I'm a Yank, not an Aussie, upside-down
and hanging on by my toes to avoid falling off ;-)
It was undoubtedly the ADT (androgen deprivation therapy), which I
suspect involved more than just Casodex.
It is a well-known SE (side effect) of ADT; but unfortunately for us,
many medics have little/no idea of the SEs of their txs (treatments). It
is scandalous. The info exists, quite often in the medication package
inserts that many medics don't bother to read. In short (No pun. Well,
maybe it is), it's well-known to those few who pay attention.
> Has anyone else got this problem, or a solution?
>
Oh yes, indeed.
See, e.g.,
http://www.prostate-cancer.org/education/localdis/scholz_newlydiagnosed2.html
See also: http://www.prostate-cancer.org/aboutus/acomplsh_research%20.html
Search on the term "penile atrophy."
The recommended tx is Viagra. Maybe other similar medications such as
Cialis are also appropriate, I dunno.
I reckon the point that must be made here and elsewhere when men are
denied the benefit of modern medicine is: Study, Learn, Take Charge!
Ignorance is Death: Knowledge is Life.
Regards,
Steve J
"If you know the enemy and know yourself, you need not fear the result
of a hundred battles. If you know yourself but not the enemy, for every
victory gained you will also suffer a defeat. If you know neither the
enemy nor yourself, you will succumb in every battle."
-- Sun Tzu, "The Art of War"
Brian - 20 Jan 2006 23:44 GMT
> Three years age I had a PSA value of 12.4 and prostate cancer was
> confirmed by a biopsy. The doctor started me on a hormone therapy
[quoted text clipped - 6 lines]
> before. Another brush off.
> Has anyone else got this problem, or a solution? Adam.
penis size arises <g> from structure and blood flow. Structure changes
from casodex aren't somethings I've heard of, but size loss from limiting
blood flow to the penis because of hormone therapy is "old hat".
A wild guess: have you got access to Viagra (or equivalent)? It works
(inter alia) by increasing blood flow to the penis. Vitamin V is commonly
in the prostate cancer survivor's tool kit <g, again>.
DP - 21 Jan 2006 00:41 GMT
> Three years age I had a PSA value of 12.4 and prostate cancer was
> confirmed by a biopsy. The doctor started me on a hormone therapy
[quoted text clipped - 7 lines]
> Has anyone else got this problem, or a solution?
> Adam.
Adam,
It is called Casodex in the US, and in Australia is know as Cosudex. As a
mono therapy, it is usually a 150MG dose per day. Is that what you are on?
As to the shortening of the penis, are you impotent? This drug at this
dosage will usually cause impotence. It can be a matter of not using the
penis regularly that can cause it to not get as large or hard. Another
thought is that when males reach puberty, the penis usually becomes the size
it will be as an adult. Cosudex is the reverse of puberty. This drug is
worse about causing male breast development that just Lupron. I can
certainly attest to that. Another side effect of ADT is usually weight gain.
If you have gained some weight around the belly, it can make the penis seem
shorter. Between the RRP, implant attempt, and ADT (with some weight gain)
my penis seems to have lost a lot of size. A vacuum pump would get more
blood into the penis and possibly regain some of the size. Properly used it
will not hurt.
Dale P
Denver, CO
Steve Kramer - 21 Jan 2006 12:40 GMT
> Cosudex is the reverse of puberty. This drug is worse about causing male
> breast development that just Lupron. I can certainly attest to that.
[quoted text clipped - 4 lines]
> penis and possibly regain some of the size. Properly used it will not
> hurt.
I never ceases to amaze me that I can continue to learn new things on this
NG. I had know idea my penis was further shortened by ADT. Certainly
explains a few things.
Thanks, DP
I.P. Freely - 21 Jan 2006 06:31 GMT
> Three years age I had a PSA value of 12.4 and prostate cancer was
> confirmed by a biopsy. The doctor started me on a hormone therapy
[quoted text clipped - 5 lines]
> cancer foundation of Australia and they said they had never heard of it
> before. Another brush off.
Makes me wonder how much your doctor told you about -- and is treating you
for -- the many other common and/or not-so-common side effects of HT. How
are you doing in that regard? Are you being treated to prevent osteoporosis,
for example?
I.P.
RR - 21 Jan 2006 07:51 GMT
A penis can get shorter as a result of RP.
Cutting tissues, scars during operation can cause it.
"Exercises" with pump may get the size back
RR
>Three years age I had a PSA value of 12.4 and prostate cancer was confirmed
>by a biopsy. The doctor started me on a hormone therapy medication called
[quoted text clipped - 7 lines]
>Has anyone else got this problem, or a solution?
>Adam.
Alan Meyer - 21 Jan 2006 16:17 GMT
Men undergoing HT often have zero desire for sex. I found that
the usual stimuli left me completely unmoved. However when I
did attempt to have sex I was surprised to find both that I was
able to do it and able to enjoy it - though it took a while to get
aroused.
It seems to me that, if we hope to stop HT someday (or even
if we don't), and if we want to keep some sexual capablity, and
if we want to continue for the sake of our wives, it's a good
idea to try to have sex - in spite of the HT.
Alan
Adam - 22 Jan 2006 01:19 GMT
> Three years age I had a PSA value of 12.4 and prostate cancer was
> confirmed by a biopsy. The doctor started me on a hormone therapy
[quoted text clipped - 7 lines]
> Has anyone else got this problem, or a solution?
> Adam.
Thank you everyone for your support and suggestions. The worst side effect
from cosudex was hot flushes every half hour day and night. Then I had a
cancerous kidney removed in Feb 2003. Then they changed me from cosudex to
androcur and the hot flushes ceased. Then I had radiation therapy for the
prostate cancer and that has left me impotent. Then they stopped the hormone
therapy altogether. So now three years later I am still impotent and with a
shortened penis.
The suggestion about viagra sounds good to me. I will pursue that idea
further.
Adam.
Alan Meyer - 23 Jan 2006 17:19 GMT
>> ...
> Thank you everyone for your support and suggestions. The worst side effect from cosudex
[quoted text clipped - 4 lines]
> with a shortened penis.
> ...
As we say in the States, you've been through the mill.
It's good to see that you're still alive and battling.
Good luck.
Alan