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Medical Forum / Diseases and Disorders / Prostate Cancer / December 2005

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Old (5 year) veteran of the PCa wars "Bruce the Muce"

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Bruce - 04 Dec 2005 20:09 GMT
Been away from the group for 3 years plus - good to see some of the names
are still familiar.
History-wise, I was diagnosed in Feb 2000, Gleason about 7.5 to 8. Radical
Prostatectomy done in May same year. Psa never went down to nil, just
hovered under 1.0. A rise over a few months in 2002 brought on radiation
(external beam). There was an immediate bloom of psa, up several notches,
for a few months, then a gradual lowering to between 0.3 and 0.35. This
stayed steady for almost 3 years then this spring a rise was noted to 0.4,
then 0.54, in August 0.7 and in October 0.93. My sense is that the curve is
becoming exponential/logarithmic, and it is time for "something". I expect
another psa test soon, and if it is higher than the 0.93 (Unfortuanately,
I'm sure it will be).  Any thoughts on this? I have contacted my local GP
who has passed the info on to my oncologist and referred me to a urologist
(first available appt March 28/06!). I'm feeling antsy 'cause I beieve that
I will be involved in the cycle of hormone blockers, then whatever else is
available whe HB's don't work anymore.  Does chemo ever start along with
HB's? Or is chemo for PCA a last ditch thing?
It would be good to hear something about all this, even if not positive.
Thanks
Steve Kramer - 04 Dec 2005 20:39 GMT
Bruce,

You are correct that you are outside you GP's area of expertise.
Traditionally, the next step his hormone blockers; also known as androgen
deprivation therapy (ADT) or hormone therapy (HT).  Mine was Lupron.

Chemo is not always last ditch, but usually it is not used at this point in
your treatment.

There is no reason why you need to wait four months.  I would get a
different urologist or oncologist.

Signature

PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05
PSA  .07 .05 .06 .05 .08
Non Illegitimi Carborundum

> Been away from the group for 3 years plus - good to see some of the names
> are still familiar.
[quoted text clipped - 16 lines]
> It would be good to hear something about all this, even if not positive.
> Thanks
alva36@gmail.com - 04 Dec 2005 20:45 GMT
Bruce-

I decided not to go that way, but a medical oncologist suggested I
start chemo when I was finished with my EBRT and HDR brachytherapy.
I've been on Zoladex and Casodex all along.  When I was finished with
the radiation, my PSA was/is undetectable, so the answer to your
question is, no, it's not a last ditch thing.

-Gordy
Bruce - 09 Dec 2005 19:35 GMT
Thanks for the input, people. I'm just waiting for my oncologist to get back
> Been away from the group for 3 years plus - good to see some of the names
> are still familiar.
[quoted text clipped - 16 lines]
> It would be good to hear something about all this, even if not positive.
> Thanks
 
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