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Medical Forum / Diseases and Disorders / Prostate Cancer / November 2005

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MRI Used to Track Path of Anti-Cancer Cells

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c palmer - 21 Nov 2005 09:46 GMT
Scientists continue to find new uses for magnetic resonance imaging
(MRI) to view the functions of organs in the body.

A team of scientists says it has developed a method to use the MRI to
track how well a certain cancer therapy is working.

In the latest issue of the journal  Nature Biotechnology , the
researchers report that implanted tiny iron oxide particles were able to
determine whether the cancer-fighting cells were on target.

"In four of the eight patients, MRI revealed that the implanted cells
weren't where they needed to be to be effective for treatment," says
Jeff Bulte, an associate professor of radiology at Hopkins' Institute
for Cell Engineering who was part of the research team. A Johns Hopkins
University news release says Bulte was the author of the report and
developed methods to use the iron oxide particles with the anti-cancer
cells.

The iron oxide technique was much more accurate than previous tracking
methods like radioactivity and ultrasound, Bulte said in the news
release. The cells in question are called dendritic cells, which
scientists theorize can stimulate the body's immune system to fight
malignant cells.



knowledge is power - growing old is mandatory - growing wise is optional    
"Many more men die with prostate cancer than of it. Growing old is
invariably fatal. Prostate cancer is only sometimes so."
http://community.webtv.net/PALMER_ENT/doc
Alan Meyer - 25 Nov 2005 03:31 GMT
In case anyone is wondering how they image the prostate
with MRI, here's how it's done:

First, you get undressed and lie on your side on a kind
of sliding table.

Then a 240 pound doctor comes in with an "endorectal
antenna" and shoves it up your arse.  He pushes, pulls
and twists it around for a while to make sure he's got it
seated right where he wants it.

Then he attaches an air pump and blows up a rubber
balloon at the end of the antenna.  That shoves the antenna
flush against the rectal wall where the prostate is.  If
you succeed in keeping your equanimity through this
you are rewarded with smiles from the attending nurses.

Next comes the MRI proper.  They slide the table into a
tube and make very loud buzzing and banging noises for
about 30 minutes or more.  Sometimes you might be
asked to hold your breath while they're doing it.

When that's all done, the 240 pound doctor comes back,
deflates the balloon, and yanks the apparatus out.

All in all, it's about the same as all the other stuff we
have to go through in our medical treatment.

   Alan
Steve Jordan - 25 Nov 2005 16:53 GMT
On November 21, Curtis Palmer wrote:

> Scientists continue to find new uses for magnetic resonance imaging
> (MRI) to view the functions of organs in the body.
[quoted text clipped - 5 lines]
> researchers report that implanted tiny iron oxide particles were able to
> determine whether the cancer-fighting cells were on target.

(snip)

This looks a lot like the Combidex procedure, presently available only in
Nijmegen(sp?), The Netherlands. It was denied FDA approval a few months
ago, but they'll try again. Dr. Strum is very positive about it.

Regards,

Steve J

"Do not go where the path may lead, go instead where there is no path and
leave a trail."
---Ralph Waldo Emerson

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