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Medical Forum / Diseases and Disorders / Prostate Cancer / November 2005Weight Loss and PSA
In the last month or so someone mentioned as part of a message that a large weight loss via exercise and diet may increase PSA reading (sorry but I haven't been able to find the post again). At the time I read that message no one had replied about this. I have been searching the net but haven't been able to find an answer. Does anyone have information/links on this please? PSA (assuming you have a prostate) can be elevated due to trauma, enlargement, infection or cancer. Trauma can include DRE, cystoscopy, prostate biopsy and transurethral resection. Wait six weeks for PSA. During '99, I had Diverticulitis and was told to wait six weeks. Infection can include prostatitis. Sexual activity can increase by 41%, so wait 2 days. Urinary retention or urinary tract infection, wait 1 week. Prostate infarction (lack of blood flow to the prostate. "One activity that does not raise PSA levels is bicycling." -- Dr. Walsh's Guide to Surviving Prostate Cancer, p. 128  SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05 PSA .07 .05 .06 .05 .08 non Illegitimi carborundum > In the last month or so someone mentioned as part of a message that a large > weight loss via exercise and diet may increase PSA reading (sorry but I [quoted text clipped - 3 lines] > I have been searching the net but haven't been able to find an answer. Does > anyone have information/links on this please? Steve, Thank you for your reply. I was diagnosed and treated for PCa via an RRP about four years ago. Since then my PSA tests have been >0.01 but the last three have shown miniscule rises - 0.01, 0.02 and 0.03. Since the last test result three months ago, I have lost around 40 lbs or so due to a diet and exercise program. The post I referred to seemed to indicate that weight loss such as this may lead to an increased PSA reading, somehow accelerating the growth of PCa cells. There is conflicting opinion on this as one paper I read on the Net actually suggested obesity may be a protection against PCa. Very confusing. I will get the latest test result next week, so perhaps the result will answer my worries (do we ever get over PSA anxiety?). Regards. That being the case, then my answer, while accurate, wasn't an answer to your question. You do not have a prostate. Therefore, your PSA would not raise and lower with trauma to or infection of the prostate gland. When you are wondering about rising PSA as a result of exercise or weight loss, more accurately you are wondering about rising PCa. My oncologist told me not to lose too much weight too fast. It had nothing to do with exercise. Exercise is always good for you. I wish I could remember why he said it. I believe it was tied to the immune system. Something about my body believing itself to be starving due to fast weight loss causes a converse reaction in the immune systems fight against cancer. I just don't remember. So, lose the weight, but do it at a rate of 2 pounds a week. And exercise all you want. SignaturePSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 G7 (3+4), T3cN0M0 Neg margins PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Lupron 07/03 (1 mo) 8/03 (4 mo), 12/03, 4/04, 09/04, 01/05, 5/05, 10/05 PSA .07 .05 .06 .05 .08 non Illegitimi carborundum > Steve, > [quoted text clipped - 13 lines] > > Regards. > Steve, > [quoted text clipped - 5 lines] > have lost around 40 lbs or so due to a diet and exercise program. The post > I referred to seemed to indicate that weight loss such as this may lead to I'm not a doctor, but your readings are really a joke if those numbers worry you. Do you realize how tiny .03 is? The margin of errror and simple anomilies has to be way bigger alone. All of them are considered untedectable according to my URO. I know the agony of PSA anxiety, but forget it and have a bagel! SignatureJK Sinrod Sinrod Stained Glass Studios http://www.sinrodstudios.com/ Coney Island Memories www.sinrodstudios.com/coneymemories/ Thanks for your replies, Steve & JK. I appreciate them. > Steve, > [quoted text clipped - 12 lines] > > Regards. There have been a number of studies indicating that obese men are more likely to die of prostate cancer than non-obese men. See http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=11319175&query_hl=4 Click the "Related" link to see similar articles. I haven't read these abstracts carefully, but I get the impression that lower body mass both reduces the likelihood of developing cancer, and increases the lifespan of people who already have cancer. I should think that losing 40 pounds, assuming you weighed too much before, is going to be good for you all around. Let us know what happens on your next PSA test, and what your doctor thinks about the rises. Hopefully, it is not an indication of recurrence of the disease. If it were an indication, hopefully the growth will stay at that linear rate - giving you a PSA of 1.0 some time between 50 and 100 years from now. Alan > > Regards. > > There have been a number of studies indicating that obese men > are more likely to die of prostate cancer than non-obese men. See http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra ct&list_uids=11319175&query_hl=4 Obese folks are more likely to die of cancer, heart desease, stroke, overeating, kidney failure, and getting hit by a truck as well... SignatureJK Sinrod Sinrod Stained Glass Studios http://www.sinrodstudios.com/ Coney Island Memories www.sinrodstudios.com/coneymemories/ > Obese folks are more likely to die of cancer, heart desease, stroke, > overeating, kidney failure, and getting hit by a truck as well... Yeah, maybe... but we almost never die from sky diving, spelunking, soccer, or jogging. |
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