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Medical Forum / Diseases and Disorders / Prostate Cancer / October 2005

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HDR Prostate Brachytherapy

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Tdub - 29 Oct 2005 18:10 GMT
A friend of mine had this procedure done at Cancer Treatment Centers of
America (http://www.brachytherapy.com/prost-brachy.html), with success.
I wish I had done it. I had RRP 2.3 yrs ago at top center by supposedly
top doctor(s). Severe incontinence, multiple procedures to try and get
the anastomsis (where they hook up the bladder to the urethra after
removal of the prostate) to stay open enough to allow the implant of an
artificial sphincter, with lots of pain and disability even now. I
could even end up having to wear an external bag (like a colostemy bag)
to collect urine. The HDR procedure seems to be more sensible
conceptually than incurring the risk of complications arising from
removing the prostate. RP surgeons aren't likely to know enough about,
or even advise patients to consider, things like HDR. It is a newer
type of procedure.
Alan Meyer - 29 Oct 2005 19:42 GMT
>A friend of mine had this procedure done at Cancer Treatment Centers of
> America (http://www.brachytherapy.com/prost-brachy.html), with success.
[quoted text clipped - 9 lines]
> or even advise patients to consider, things like HDR. It is a newer
> type of procedure.

I had HDR brachytherapy.  So far (crossing my fingers and knocking
furiously on wood) I'm happy with it.  If my cancer comes back I
may wish I had chosen surgery.

I chose radiation because, in reading all of the literature I could,
it seemed that the incidence of nasty complications and side effects
is lower than with surgery and the treatment outcome is about the
same.  I had come out of the only surgery I ever had, a knee
arthroscopy, much worse than when I went in.  So I was shy about
surgery to begin with.  Then I talked to a friend who had had RP
and almost died from an embolism a week after the procedure.
Finally, the surgeon my HMO sent me to just didn't inspire any
confidence in me.

However there is still considerable debate about whether radiation
is as effective as surgery.

Nasty side effects are possible with radiation as well as with
surgery.  Some radiation patients will get bladder or rectal cancer
years later because of radiation damage.  Some have chronic
proctitis (pain in the a.s).  Some become impotent.  Some
experience urinary difficulties.  A few can experience incontinence
though it's much rarer than with surgery.

Some guys seem to sail through RP with no pain and few side
effects and other guys get clobbered.  I'm sure that part of the
outcome is the skill of the surgeon, but part is probably just good
or bad luck.

It sounds like you got clobbered.  I hope at least that your cancer
is gone and that the side effects will abate over time.

Good luck with it.

   Alan
Steve Jordan - 29 Oct 2005 20:24 GMT
On October 29, Alan Meyer wrote, in pertinent part:

(snip)

> Some radiation patients will get bladder or rectal cancer
> years later because of radiation damage.

(snip)

I'm a graduate of IMRT, post one year.

I'd appreciate it if Alan would furnish some further info on this; perhaps
peer-reviewed studies.

Thanks.

Regards,

Steve J

"Facts are stubborn things; and whatever may be our wishes, our
inclination, or the dictates of our passions, they cannot alter the state
of facts and evidence."
 --John Adams
Alan Meyer - 29 Oct 2005 22:09 GMT
> On October 29, Alan Meyer wrote, in pertinent part:
>
[quoted text clipped - 9 lines]
> I'd appreciate it if Alan would furnish some further info on this; perhaps peer-reviewed
> studies.

I specifically asked my first radiation oncologist if there was increased
risk and she said no.  But my current radiation oncologist told me I was
at increased risk and, starting at five years after treatment, should have
regular exams to catch any possible cancers early.

Here's a report of a 2005 study of 30,552 patients receiving radiation
between 1973 and 94.  It claims a clear increased risk.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=15825064&query_hl=1


There are some countervailing opinions.  Here's one claiming that, up
to 10 years after radiation, there was no increased risk:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=9607337&query_hl=3


Here are two that claim there is a risk.  Both say the risk is relatively small,
but requires watching:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=10640974&query_hl=3


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=9316648&query_hl=3


All of these studies necessarily involve less advanced radiation techniques
than those used today.  I'm hoping that whatever carcinogenic effect
radiation has, it has been reduced by modern techniques.  IMRT and
brachytherapy may both reduce the exposure of organs outside the
prostate, though I believe that the proximity of those organs makes it
impossible to completely avoid irradiating them.

My oncologist performed a proctoscopy on me 1 year after the radiation
and put it on the screen for me to see.  I could see considerable
radiation damage to the rectal wall near the prostate.

   Alan

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