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Medical Forum / Diseases and Disorders / Prostate Cancer / October 2005

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daVinci Robot article in the Boston Globe

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A Sherman - 01 Oct 2005 17:34 GMT
Today's Boston Globe has a feature article on Robotic Surgery.  It contains
nothing that has not been already discussed here.  If you want to read it on
line, it is available for a couple of days at
http://www.boston.com/news/nation/articles/2005/10/01/robotic_surgery_gets_new_push/

I thought it was particularly noteworthy that some of the doctors who were
interviewed had very little experience with the robot. Dr McRae had done
"about a half dozen cases" and Dr Babayan had done about 30.

Al
Steve Jordan - 01 Oct 2005 21:22 GMT
> Today's Boston Globe has a feature article on Robotic Surgery.  It contains
> nothing that has not been already discussed here.

(snip)

> I thought it was particularly noteworthy that some of the doctors who were
> interviewed had very little experience with the robot. Dr McRae had done
> "about a half dozen cases" and Dr Babayan had done about 30.

Ahem: nitpick warning.

Robert A. Heinlein would not be pleased. The thing is not a robot, it's a
waldo.

Regards,

Steve J

"Perturb not Dragons, for you are crunchy and tasty with a bit of ketchup
and thyme."
-- Unknown
ross lazarus - 02 Oct 2005 01:15 GMT
Interesting. I had a lap RP but by hand rather than robot. From my (extensive!) interviewing of the
surgeon who did it (and he did a truly spectacularly great job in terms of continence and erectile
function) I gained the impression that he thought the robot could make a good open surgeon into a
good laparoscopic surgeon very quickly - but that non-robotic lap surgery was something fewer good
open surgeons ever got to be good at. More importantly, the cost of the robot and the consumables
was very high. He strongly emphasised the issue mentioned in the article - that using direct lap
instruments in his hands he got to feel the tissue directly which he preferred - albiet via a long
stick down a thin tube! And he emphasised the benefits of having a surgeon who's done hundreds of
that specific procedure - there's a steep learning curve.

> Today's Boston Globe has a feature article on Robotic Surgery.  It contains
> nothing that has not been already discussed here.  If you want to read it on
[quoted text clipped - 4 lines]
> interviewed had very little experience with the robot. Dr McRae had done
> "about a half dozen cases" and Dr Babayan had done about 30.
judamd@aol.com - 02 Oct 2005 07:27 GMT
My surgeon also did lap surgery on me without the robot.  He had done
his first 40 laps with the robot but felt he could do a better and
faster job without it.  I was his 126th lap patient - he had done many
hundreds of open surgeries as well.  The robot he used was collecting
dust at the hospital since he and the other docs who had used it like
the regular lap procedure better or preferred open surgery.  He did say
the robot is useful in that it allows the doctor to "take an occasional
break" since the implements are remotely controlled whereas in the
regular procedure the doctor is continually standing over the patient
operating the equipment directly.  He also indicated that there was an
additional amount of time (about one hour) under anesthesia to set up
the robot before the actual surgery can begin.  No matter, my results
were not specatular in that I'm two years out, still dribbling, and
little Willie continues his hibernation.  Gotta love those low PSAs
though.
Dave Perry

> Interesting. I had a lap RP but by hand rather than robot. From my (extensive!) interviewing of the
> surgeon who did it (and he did a truly spectacularly great job in terms of continence and erectile
[quoted text clipped - 14 lines]
> > interviewed had very little experience with the robot. Dr McRae had done
> > "about a half dozen cases" and Dr Babayan had done about 30.
Steve U - 02 Oct 2005 21:53 GMT
In defense of the Da Vince, I had a my robotic sugery in Feb 04 by Dr
Joseph Wagner in Hartford. My results are excellent by the most
stringent standards. He has done hundreds of them. When I was shopping,
it looked to me like there are talented docs getting good outcomes with
open, with hand lap, and with robotic lap. The first cut was open vs
lap. If you can get the same good results with less suffering, thats a
good  enough reason for me to pick lap. On the hand vs robotic, I found
the idea that the doc can see better, and work without tremor, fatigue,
and awkward posioning to be compelling.
As for cost, all technology is very costly at the start, then comes
down as it gets more common. The cost to me was less with the robot
because I had less down time.
Steve U
ron - 02 Oct 2005 22:55 GMT
Steve U wrote...snip...
> If you can get the same good results with less suffering, thats a
> good  enough reason for me to pick lap.

Steve...When you use the phrase "same good results" I assume you mean
recurrence-free survival.  To my knowledge, equivalent freedom from
biochemical recurrence at 5, or of course even better 10, years
post-treatment has not been demonstrated for lap or robotic vs open RP.
To me this is a key point.

A recent Medscape review of the 2005 AUA meeting made the following
comment on the situation, "The positive surgical margin rate continues
to be higher with laparoscopic and robotic prostatectomy compared with
the open approach.[54,69,70] It is unclear how this will translate into
disease-free and overall survival, since the laparoscopic and robotic
experience is still immature. Nonetheless, it is cause for concern."
Even Guillonneau, the man who adapted lap procedures to RRP, has
recently said, "Nevertheless, longer followup and more mature data are
needed definitively to establish laparoscopic radical prostatectomy as
an alternative to the retropubic approach."

While we all hope that LRP or RLRP will be equivalent or superior to
RRP in terms of disease-free survival, I don't think that very
important point has yet been demonstrated...Best wishes and good
health, Ron
ross lazarus - 03 Oct 2005 01:36 GMT
Funny you should raise this - I've just reviewed some real data on that very issue.

I'm a medical epidemiologist, so when I got back to work, my surgeon asked me to check over an
analysis they'd just completed on a 1000 consecutive RPs in their urology unit (the series was
closed before I was operated!) - about 280 laps and the rest open. No significant difference in
positive margin risk for open vs lap after adjustment for patient characteristics in a logistic
regression model.

With a finding of no difference, the first question is whether there was enough statistical power,
but 1000 cases gives a reasonable probability to detect an important difference if there was one. It
will be published soon - but you heard it first on ascp :-)

> While we all hope that LRP or RLRP will be equivalent or superior to
> RRP in terms of disease-free survival, I don't think that very
> important point has yet been demonstrated...Best wishes and good
> health, Ron
ron - 03 Oct 2005 02:51 GMT
Ross...Any idea why your conclusions differ from those in references
54, 69 and 70 cited above?  That would be an important point to address
in the publication, IMO.  Further, was there a difference in the
positive margin locations between the open and lap groups?  Finally,
280 laps out of 1000 cases doesn't sound like a highly-powered study to
me; that's just my opinion, I'm not a statistician and I'm not trying
to be cantankerous...Best wishes and good health, Ron
ross lazarus - 03 Oct 2005 03:30 GMT
> Ross...Any idea why your conclusions differ from those in references
> 54, 69 and 70 cited above?  That would be an important point to address

Haven't read them so no idea. I'll have to read them thanks!

> in the publication, IMO.  Further, was there a difference in the
> positive margin locations between the open and lap groups?  Finally,

Positive distal and proximal margins were relatively uncommon so not informative to test separately.
Peripheral margins were the largest group of positives as is expected with this disease.

> 280 laps out of 1000 cases doesn't sound like a highly-powered study to
> me; that's just my opinion, I'm not a statistician and I'm not trying

Power to detect a difference is always higher with more cases or larger subgroups, but it's hard to
collect high quality data on large series - 1000 is a reasonable sample in this game AFAIK. Ideally,
all surgeons and urology groups would contribute their outcomes data to a central repository so we
could make better informed Rx decisions. Sadly, in my experience, getting a group of surgeons to
agree on just about anything is like herding cats....

> to be cantankerous...Best wishes and good health, Ron

We academics tend to be cantankerous by profession, so feel free while you live well, and long :-)
Steve U - 04 Oct 2005 00:13 GMT
Ron, You wrote "When you use the phrase "same good results" I assume
you mean
recurrence-free survival. "
I don't. The robot has not been around long enough, but who has 15
years to make their decision? I used clean margin as a surogate for
indicating increased chance of cure. My doc's record was 29% positive
for open, and 22% positive for RLRP. This was consistent with numbers
published by Tewari and Menon in the British Journal of Urology 92:205,
2003, and Ahlering in Urology 63:819, 2004. I think many studies using
combined data include people who have not done many cases and/or are
not that good at it. Also, there is some cherry picking going on at
some places. Other docs take more challenging cases. I heard DrMenon
speak a few months back. He complained about the dificulty he has had
getting things published about robotic results. Of course
I'm now totally sold and biased because I was ready to go back to work
day #6, have no urinary symptoms, and I got my erection back. The
literature is a sea of doubt. My own results are personally very
compelling. Be well.
Steve U
 
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