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Medical Forum / Diseases and Disorders / Prostate Cancer / August 2005Prostate cancer and weight loss
My dad has a history of very high PSA, though he has not been diagnosed with the cancer, with 3 negative biopcies - see his PSA history below. He is 68, and looks like he's started losing weight recently. Is weight loss typical for a prostate cancer (I mean, weight loss is probably typical for any very advanced cancer, but he should not have it very advanced based on his PSA) ? 09/94 PSA = 4.9 10/97 PSA = 8.0 11/97 PSA = 12.0 11/97 Negative biopsy 08/99 PSA = 12.6, free PSA = 7.1% (low!) 10/99 Negative biopsy 05/00 PSA = 15.9 01/01 PSA = 13.0 06/01 PSA = 12.4 03/02 PSA = 14.0 10/02 PSA = 20.0, free PSA = 15% 10/02 Negative biopsy 11/02 PSA = 17.8 08/03 PSA = 21.9 10/03 PSA = 23.3 03/04 PSA = 15.6 03/05 PSA = 15.1 >My dad has a history of very high PSA, though he has not been diagnosed >with the cancer, with 3 negative biopcies - see his PSA history below. [quoted text clipped - 20 lines] >03/04 PSA = 15.6 >03/05 PSA = 15.1 Pretty tough for us armchair doctors to say. Hasn't he asked his uro? My PSA is 26 and I don't think I have cancer (4 negative biopsies and several negative DREs). Ask someone who is qualified and knows the history. Ed I'm not a doctor, but no, I have never seen weight loss listed as a symptom of PCa. jimhoney > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. [quoted text clipped - 20 lines] > 03/04 PSA = 15.6 > 03/05 PSA = 15.1 > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. > He is 68, and looks like he's started losing weight recently. Is weight > loss typical for a prostate cancer (I mean, weight loss is probably > typical for any very advanced cancer, but he should not have it very > advanced based on his PSA) ? Don't know about the weight loss but does your father suffer from bph? If so, that may be causing the high psa numbers. Prior to having a TURP in 1998 my psa, over a period of several years, went from 4 to 17. I also had two negative biopsies during this time. Following the TURP it dropped back to 4 and has stayed there since. I have never had a reading much less than 4. At the time my uro said that bph could cause higher psa readings. Don "Alex" <arazumo@hotmail.com> wrote... > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. > He is 68, and looks like he's started losing weight recently. Is weight > loss typical for a prostate cancer (I mean, weight loss is probably > typical for any very advanced cancer, but he should not have it very > advanced based on his PSA) ? Hi Alex, a PSA of 4 should be 'normal' for a 68 yrs man. 10 isn't very high. (I'm 62 and no history yet, when measured it was 416, I read resently) Yes I do have cancer and I'm gaining weight, because of keeping fluid in, or lymph oedeem or such. A little blood test will give some indication. The thyroid gland is suspect, I think. Douwe Hi Alex. Another thought about your dad's weight loss...is there diabetes in the family? Excessive thirst or urination on his part? I'm sure you'll ask the doc. Good wishes, Ron B. Chicago ... > A little blood test will give some indication. The thyroid gland is > suspect, I think. I went from 150 to 134 pounds during a bout of hyperthyroidism. It also gave me a rapid heartbeat - which was a significant indication. Alan > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. [quoted text clipped - 20 lines] > 03/04 PSA = 15.6 > 03/05 PSA = 15.1 Generally, one would expect a prostate cancer advanced enough to produce weight loss to be detectable on biopsy. But all sorts of strange things happen. For example, it could be that a very small cancer, which is missed on biopsy still managed to metastasize. All this, however, is just conjecture. The weight loss probably doesn't have anything to do with prostate cancer, but since it could indicate something which needs to be treated, he ought to have a thorough medical workup. >My dad has a history of very high PSA, though he has not been diagnosed >with the cancer, with 3 negative biopcies - see his PSA history below. [quoted text clipped - 20 lines] >03/04 PSA = 15.6 >03/05 PSA = 15.1 Alex I lost about 15 pounds as I was initially diagnosed with metestatic PCA. I believe it was about the time I started on hormone therapy. My apetite was really reduced and I was having severe in pain in the ribs. I have since stabablized at 10 pounds under my pre diagnosis weight. I don't know what PSA signifies advanced cancer. My PSA was off the scale so there wasn't much argument about whether it was advanced or not. My PSA is down to the 6 range and I feel much better, except for the side effects of the hormones. My sister has survived three different serious cancers and lost weight with each one. Her daughters husband died of brain cancer and lost very little weight with it Jim ... > I lost about 15 pounds as I was initially diagnosed with metestatic > PCA. I believe it was about the time I started on hormone therapy. [quoted text clipped - 10 lines] > very little weight with it > Jim ... I love to hear stories of men with advanced cancer who have gotten it under control and are living a fairly normal life. I hope the hormones continue to work for you for many, many years. There have been a number of relatively successful clinical trials of treatments (I'm thinking particularly of phenoxodiol and the cancer vaccines) for men who have become hormone refractory. If and when that happens to you, I'm hoping that the new treatments will keep your cancer under control. Best of luck. Alan > My dad has a history of very high PSA, though he has not been diagnosed > with the cancer, with 3 negative biopcies - see his PSA history below. > He is 68, and looks like he's started losing weight recently. Is weight > loss typical for a prostate cancer (I mean, weight loss is probably > typical for any very advanced cancer, but he should not have it very > advanced based on his PSA) ? My opinion is you have it right. No connection in his case. Nerves?  SignatureJK Sinrod Sinrod Stained Glass Studios www.sinrodstudios.com Coney Island Memories www.sinrodstudios.com/coneymemories |
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