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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2005

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can treatment for recurrence of prostate cancer be far behind......

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c palmer - 17 May 2005 10:04 GMT
i was watching a west coast news broadcast of ktla last night and they
had a news item about herceptin.

it is a drug used in the fight against recurrence of breast cancer and
studies have found it to be be affective on 46% of the cases it has been
used on.   what makes this drug so different is that it doesn't attack
the good cells, only the estrogen positive recurring cancer cells.

since the female and male cancer here are so close in behavior as to how
the spread and how the treatments are very similar, i wonder how long it
will be before the male side will have a drug similar for the use in the
treatment of the recurrence of prostate cancer with at least a 50%
success rate.

~ curtis

knowledge is power - growing old is mandatory - growing wise is optional    
"Many more men die with prostate cancer than of it. Growing old is
invariably fatal. Prostate cancer is only sometimes so."
http://community.webtv.net/PALMER_ENT/doc
Ed Friedman - 17 May 2005 17:43 GMT
> i was watching a west coast news broadcast of ktla last night and they
> had a news item about herceptin.
[quoted text clipped - 11 lines]
>
> ~ curtis

Curtis,

You raise a good point, but since breast cancer usually has a high
Estrogen Receptor(ER)-alpha to ER-beta ratio and prostate cancer has a
high ER-beta to ER-alpha ratio, drugs like herceptin are unlikely to
help prostate cancer.  However, as soon as an ER-alpha blocking drug
becomes FDA approved, then it should be effective against both prostate
and breast cancer (in both cancers, ER-alpha upregulates bcl-2 and
ER-beta downregulates bcl-2).

Ed Friedman
 
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