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Medical Forum / Diseases and Disorders / Prostate Cancer / April 2005

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Prostate Cancer 'Lumpectomy' Tested

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Dick Smith - 02 Apr 2005 00:29 GMT
Prostate Cancer 'Lumpectomy' Tested

Preliminary Results Look Promising

By Miranda Hitti
WebMD Medical News  Reviewed By Brunilda  Nazario, MD
on Friday, April 01, 2005

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April 1, 2005 -- A new, approach to prostate cancerprostate cancer has
reportedly fared well in early tests.

The technique, called focal cryoablation, targets tumors without
harming healthy tissue. Gary Onik, MD, who tested the procedure on a
small group of prostate cancer patients, calls it "lumpectomy" for
prostate cancer.

The technique still needs long-term study but could be a "major and
profound departure from the current thinking about prostate cancer,"
says Onik, in a news release.

Onik pioneered prostate cancer cryoablation in the early 1990s, says
the news release. For more than five years, Medicare has approved
cryoablation of the whole prostate gland. The new technique refines
that strategy, zeroing in on tumors, not the entire prostate.
ron - 02 Apr 2005 01:01 GMT
It's the multifocal nature of PCa that makes this approach
problematical.  Was it Walsh who said that there are typically 5-7
tumor sites, or some number like that?  I suppose that as imaging
methods improve, focal cryoablation might have a better chance of
success.  Just my thoughts...Best wishes and good health, Ron
jhhtexas@ieee.org - 02 Apr 2005 01:10 GMT
> It's the multifocal nature of PCa that makes this approach
> problematical.  Was it Walsh who said that there are typically 5-7
> tumor sites, or some number like that?  I suppose that as imaging
> methods improve, focal cryoablation might have a better chance of
> success.  Just my thoughts...Best wishes and good health, Ron

I have read some real horror stories on crybolation. If it doesn't
work, salvage treatments are difficult. Also, it can really damage the
erectile nerves that are in proximity to the prostate.
jhhtexas@ieee.org - 02 Apr 2005 01:10 GMT
> It's the multifocal nature of PCa that makes this approach
> problematical.  Was it Walsh who said that there are typically 5-7
> tumor sites, or some number like that?  I suppose that as imaging
> methods improve, focal cryoablation might have a better chance of
> success.  Just my thoughts...Best wishes and good health, Ron

I have read some real horror stories on crybolation. If it doesn't
work, salvage treatments are difficult. Also, it can really damage the
erectile nerves that are in proximity to the prostate.
jhhtexas@ieee.org - 02 Apr 2005 01:11 GMT
> It's the multifocal nature of PCa that makes this approach
> problematical.  Was it Walsh who said that there are typically 5-7
> tumor sites, or some number like that?  I suppose that as imaging
> methods improve, focal cryoablation might have a better chance of
> success.  Just my thoughts...Best wishes and good health, Ron

I have read some real horror stories on crybolation. If it doesn't
work, salvage treatments are difficult. Also, it can really damage the
erectile nerves that are in proximity to the prostate.
jhhtexas@ieee.org - 02 Apr 2005 01:11 GMT
> It's the multifocal nature of PCa that makes this approach
> problematical.  Was it Walsh who said that there are typically 5-7
> tumor sites, or some number like that?  I suppose that as imaging
> methods improve, focal cryoablation might have a better chance of
> success.  Just my thoughts...Best wishes and good health, Ron

I have read some real horror stories on crybolation. If it doesn't
work, salvage treatments are difficult. Also, it can really damage the
erectile nerves that are in proximity to the prostate.
Alan Meyer - 02 Apr 2005 18:34 GMT
> It's the multifocal nature of PCa that makes this approach
> problematical.  Was it Walsh who said that there are typically 5-7
> tumor sites, or some number like that?  I suppose that as imaging
> methods improve, focal cryoablation might have a better chance of
> success.  Just my thoughts...Best wishes and good health, Ron

I have the same doubts.

If there are 5-7 observable tumor sites, how can you be sure
of hitting them all.  And how many microscopic tumor sites are
there?

On the other hand, if the treatment could be applied repeatedly
it might be interesting.  Zap each tumor as it becomes big
enough to see.

This is one experimental trial I don't think I'd participate in.

   Alan
Tom Cular - 02 Apr 2005 18:45 GMT
Alan,
In about the same time frame that I decided on seeds a co-worker told me of
a friend who had chosen cryo. I asked if he had looked into other posssible
treatments and was told a week later that the guy was advised by his GP that
cryo was the way to go! He did not seek any other alternatative treatments.
I haven't spoken to my former co-worker in at least a year, I'll make an
effort to do so and inquire about his friend.

Tom

> > It's the multifocal nature of PCa that makes this approach
> > problematical.  Was it Walsh who said that there are typically 5-7
[quoted text clipped - 15 lines]
>
>     Alan
Alan Meyer - 03 Apr 2005 07:11 GMT
> Alan,
> In about the same time frame that I decided on seeds a co-worker told me of
[quoted text clipped - 3 lines]
> I haven't spoken to my former co-worker in at least a year, I'll make an
> effort to do so and inquire about his friend.

Presumably he will get cryosurgery on the entire prostate, not
just on tumor lumps.  Without knowing anything about the relative
merits of cryo vs. radiation or surgery, I'd still think that that form
of cryo is less risky than one that just aims at tumor sections.

However I would like to hear about his experience.  Was the treatment
effective (at least so far)?  What side effects did he experience?

   Alan
 
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