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Medical Forum / Diseases and Disorders / Prostate Cancer / February 2005Informative Medical website
Hello again all Seeing I have multiple ailments to complement my PCa, I stumbled across this website, which has real Medical factual info on just about everything. You need to register with a User/Password and you can Search on what you want. Type in "Prostate Cancer" and see what you get! http://www.medscape.com/px/urlinfo -- Reader to complete... -- Please reply to this ng as my email adress is fake: -- Regards -- CC You can also select sections like "Urology" and they will deliver a weekly update, with links to relevant articles, to your mailbox...Ron > You can also select sections like "Urology" and they will deliver a > weekly update, with links to relevant articles, to your mailbox...Ron ron, In the discussion of the finasteride study, I encountered the following sentence. Does it make any sense to you? "Biopsies performed at study end showed clinically significant cancers in a sizeable proportion of men with PSA values in the so-called "normal" range: 15% had prostate cancer on end-of-study biopsy, and 15% of these had high-grade cancers, representing 29% of the entire population." 15 percent of 15 percent is 2.25 percent. I also believe I understand English grammar. What am I missing? > In the discussion of the finasteride study, I encountered the following > sentence. Does it make any sense to you? [quoted text clipped - 6 lines] > 15 percent of 15 percent is 2.25 percent. I also believe I understand > English grammar. What am I missing? Could it be that the 2.25% constitutes 29% of all high-grade cancers detected? What's the journal reference to this discussion?..Ron >>In the discussion of the finasteride study, I encountered the > [quoted text clipped - 23 lines] > Could it be that the 2.25% constitutes 29% of all high-grade cancers > detected? What's the journal reference to this discussion?..Ron For the abstract, try http://intapp.medscape.com/px/medlineapp/getdoc?pmi=15163773&cid=med but you may have to login to Medscape first. The abstract doesn't seem to say anything about 29 percent. The original statement is at www.medscape.com/viewprogram/3440 Click on 1. and follow the article through several pages. It must be a typo, as you suspected. In the original paper the authors state, "High-grade cancers (those with a Gleason score of at least 7) were observed throughout this range of PSA values and had an overall prevalence of 2.3 percent.". The range of PSA values being less than or equal to 4.0 ng/ml. Perhaps 2.3% became 29%? I could find no mention of any statistic around 29% in the original full text...Ron <snip> >"Biopsies performed at study end showed clinically significant cancers >in a sizeable proportion of men with PSA values in the so-called [quoted text clipped - 3 lines] >15 percent of 15 percent is 2.25 percent. I also believe I understand >English grammar. What am I missing? Your space-shuttle trajectory Math are perfect, but if you remove the "of these" from the sentence, you are closer to the 29% (possibly a rounding-down error due to the unpredictable Ozone Layer) *smirk*. -- Reader to complete... -- Please reply to this ng as my email adress is fake: -- Regards -- CC > <snip> > [quoted text clipped - 9 lines] > "of these" from the sentence, you are closer to the 29% (possibly a > rounding-down error due to the unpredictable Ozone Layer) *smirk*. But the abstract (and the original article, which ron checked), which the statement referred to, gave the actual numbers. There is no doubt that "of these" is part of the intended meaning. There seems to be no sense in adding the two numbers together. > -- Reader to complete... > -- Please reply to this ng as my email adress is fake: > > -- Regards > > -- CC <snip> >But the abstract (and the original article, which ron checked), which >the statement referred to, gave the actual numbers. There is no doubt >that "of these" is part of the intended meaning. There seems to be no >sense in adding the two numbers together. I managed to find the article in question and tend to agree with you that the compounded percentages are meaningless and have no relation to the next-mentioned 29%. I also read the Abstract No. 28 and it had no bearing on the percentages. Sometimes my Rad Oncologist babbles off a stream of Probability percentages and when I leave his room, I wonder if I'm going to make it to the car LOL Overall, I still find the medscape site very informative for my own string of ailments. -- Reader to complete... -- Please reply to this ng as my email adress is fake: -- Regards -- CC |
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