http://news.newkerala.com/india-news/?action=fullnews&id=47910
Vitamin E can halt prostate and lung cancer: Study:
[Health India]: Washington, Dec 15 : A new study, conducted by scientists at
the Purdue University, has found that the form of vitamin E found in many plant
seeds, but not in most manufactured nutritional supplements, might halt the
growth of prostate and lung cancer cells.
They found that gamma-tocopherol, which occurs naturally in walnuts, pecans,
sesame seeds, and in corn and sesame oils, inhibits the proliferation of
lab-cultured human prostate and lung cancer cells.
The vitamin's presence interrupts the synthesis of certain fatty molecules
called sphingolipids, important components of cell membranes. However, the
gamma-tocopherol leaves healthy human prostate cells unaffected, which could
give it value as an anticancer agent.
The study, which has been published in the journal 'Proceedings of the National
Academy of Sciences,' however said that because most nutritional supplements
contain only alpha-tocopherol, a different form of vitamin E that alone does
not have these anticancer properties, it may be better to supplement the diet
with mixed forms of vitamin E.
The researchers indicated that gamma-tocopherol inhibits inflammation, which
had already been implicated in cancer development. They theorized that it might
retard the progress of cancer and cardiovascular disease, and to test their
hypothesis they exposed cultures of cancerous prostate and lung cells to the
vitamin. Normal prostate epithelial cells were used as a control group.
They said that the vitamin could be used to target lung and prostrate cancer
cells without the damaging side effects of chemotherapy.
The study also revealed that gamma-tocopherol caused cell death by interrupting
sphingolipid synthesis. (ANI)
---MIKE--- - 15 Dec 2004 15:49 GMT
There is a clinical trial going on right now that is using Gamma E and
Selenium. There are four groups -Gamma E alone, Selenium alone, Gamma E
plus Selenium, and placebo. Since these products are easily available,
I can't understand why a person would want to take part in this trial.
I take Gamma E plus Selenium every day. My PSA (which was rising slowly
after seeds) seems to be staying around 3.4. (I also take flaxseed,
boron, licorice, and tomato juice (lycopene).
---MIKE---
Leonard Evens - 15 Dec 2004 18:31 GMT
> There is a clinical trial going on right now that is using Gamma E and
> Selenium. There are four groups -Gamma E alone, Selenium alone, Gamma E
[quoted text clipped - 3 lines]
> after seeds) seems to be staying around 3.4. (I also take flaxseed,
> boron, licorice, and tomato juice (lycopene).
The trial is to see whether or not any of these vitamins, alone, or in
combinatio, are any better than a placebo. At present, there are some
theoretical reasons for expecting them to be effective and also some
indirect evidence. But the best way to be sure is to have head to head
comparisons with randomly chosen subjects.
The trial doesn't enroll men who have been diagnosed with prostate
cancer, so its purpose is to see whether or not any of these work to
prevent prostate cancer from developing in the first place, not whether
or not it will prevent recurrence.
At best, if these vitamins are helpful it will be a modest effect. They
won't prevent prostate cancer entirely, but they may reduce the
likelihood of it. Any one man in the trial won't be risking a lot, even
if he is in the placebo group. I'm not sure what inducements they
offer except for helping medical science and receiving free prostate
cancer testing, but apparently they have been able to get enough men to
sign up. Of course, if it turns out early on that there is a definite
advantage, they will probably stop the trial early and advice men to
take the combination that seems to be effective.
> ---MIKE---
I.P. Freely - 15 Dec 2004 17:48 GMT
OTOH, ask Google agout Omega oils and prostate cancer. There are many
well-documented concerns and contradictions about many of these oils and
their effect on PC which may more than offset any vit E benefit.
I.P.
> http://news.newkerala.com/india-news/?action=fullnews&id=47910
>
[quoted text clipped - 30 lines]
> The study also revealed that gamma-tocopherol caused cell death by interrupting
> sphingolipid synthesis. (ANI)