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Medical Forum / Diseases and Disorders / Prostate Cancer / October 2004

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Condense Gleason Score

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John Loomis - 30 Oct 2004 02:28 GMT
Hey Guys, and Gals,
What a huge amount of info concerning Gleason Scores etc.
We need to condense this.  Make it easy for all to understand.
All of the info we have can be condensed.
Would it not be nice if someone took it upon themselves to make  version
that is easily read, and determined.
I know, I will get a lot of slack....
Would'nt it be nice.
Look up the score, see the age of diagnosis, determine the avenue.....
I agree it is not simple, but seems what we are eventually heading for.
Radiation, Age, and RP....hum, I am very confused.
Leonard Evans is very well versed.
We do need a "sampler" a list of things.....age considered.....sex.
desires.....and life style.....
Moving ahead....just checking in.
I Vote for Kerry! my 2 peanuts.
After all, I come from Calif.
Love you all, John Loomis
Danny McCarty - 30 Oct 2004 21:05 GMT
>Subject: Condense Gleason Score
>From: "John Loomis" jloomis@mcn.org
[quoted text clipped - 7 lines]
>Would it not be nice if someone took it upon themselves to make  version
>that is easily read, and determined.

The Phoenix site?

>I know, I will get a lot of slack....
>Would'nt it be nice.
[quoted text clipped - 8 lines]
>After all, I come from Calif.
>Love you all, John Loomis
c palmer - 31 Oct 2004 03:12 GMT
hi john - as we improve in technology and data gathering - it is just a
matter of time before we get as many variables to stabilize within a
perimeter range that will prove out to be a correlation.   the partin
table is definitely a great start and perhaps the table and be refined
to tighter numbers as the data comes forth to what you are describing.
it will probably take more details to input to give the person with pca
a better idea of where they stand and my crystal ball says that in the
future having pca might read like this......

example.   mr. X.   age xxxx.  psa.xxx  stage xxxx.  gleason xxxxx,
cores positive xxxx,   quadrant located in xxxx,  per cent involvement
xxxx,  cat scan input xxxxx,  bone scan input xxxxx,  (plus some other
inputs that are in development)

diagnosed stage of pca and projected outcomes.......

surgical procedure -  standard RP
xxxx%  success,  RRP xxxx% success, LRP xxxx% success,

radiation procedure - IMRT xxxx% success, EBRT xxxx% success,
brachytherapy xxxx% success
HDT xxxx% success, proton xxxx% success.

cryosurgery procedure - xxxx% success

watchful waiting - projected time to mets xxx years.  projected time to
end of life xxx years.

hormone therapy - projected time xxx years

combination of treatments........

surgical/radiation treatment xxxx% success

chances of complication from surgery treatment....  standard RP xxxx%,
RRP xxxx%,  LRP xxxx%.

chances of complication from radiation therapy...... IMRT xxxx%,  EBRT
xxxx%,
brachytherapy xxxx%, HDT xxxx%,
proton xxxx%.

chances of complication from cryosurgery xxxx%.

projected chance of recurrance of pca....

by surgical - standard RP xxxx%, RRP xxxx%, LRP xxxx%.

by radiation - IMRT xxxx%, EBRT xxxx%,
brachytherapy xxxx%, HDT xxxx%, proton xxxx%.

cryosurgery xxxx%

this is only off the top of my head that i put this together, but if one
was dx'ed with pca and got all the facts they could and were able to get
a readout such as this, by seeing the results in black and white, may
make it easier to make the right choice for their particular case.

i'm sure that others can add to what i've missed but this concept was
just something i was toying with.

~ curtis

knowledge is power - growing old is mandatory - growing wise is optional    
"Many more men die with prostate cancer than of it. Growing old is
invariably fatal. Prostate cancer is only sometimes so."
Steve Kramer - 31 Oct 2004 12:02 GMT
I have a feeling we'll have a cure before medicine and mathematics figure
that one out.

Signature

Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000 G7 (3+4), T3bN0M0
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Lupron (1 mo) 07/21/2003 @ 48
PSA  .07 .05 .06
Lupron (3 mo) 8/03 (48), 12/03, 4/04 (49), 09/04 (50)
non illegitimi carborundum

> hi john - as we improve in technology and data gathering - it is just a
> matter of time before we get as many variables to stabilize within a
[quoted text clipped - 62 lines]
> "Many more men die with prostate cancer than of it. Growing old is
> invariably fatal. Prostate cancer is only sometimes so."
 
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