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Medical Forum / Diseases and Disorders / Prostate Cancer / August 2004

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update - psa post seeds

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Paket41 - 08 Aug 2004 18:22 GMT
Steve Kramer wrote:
"Good?  That's fantastic.  There isn't another brachy patient here with a
0.10 PSA.  I don't think there is a 0.10 PSA here among any ratiation
treatment of any kind!  Excellent!!!!!!!!!"

I agree, 0.1 is great.  But there are other brachy patients at 0.1.  I had 111
Pd103 seeds implanted 5/17/01, no HT and no EBRT.  PSA was 4.4 before seeding,
Gleason 3+3=6, age 59.  After seeding, my PSA dropped as follows:
08/01  --  0.5
11/01  --  0.3
05/02  --  0.2
11/02  --  0.1
05/03  --  0.1
11/03  --  <0.1 (ND)
05/04  --  <0.1 (ND)
I'm sure I'm not the only one, as my Rad Onc told me approx 2/3 of his patients
level out near 0.1, and approx 1/3 at undetectable.
Paul Ketterer
Steve Kramer - 08 Aug 2004 21:22 GMT
Sorry, Paul.  Haven't heard from you since November.  I didn't know you were
still around.

Your numbers are fantastic.  I would imagine they are the best one can hope
for.

Signature

Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Erection 05/12/2003 @ 48
HTbegins 07/21/2003 @ 48
PSA  .07 .05
Lupron 7/03, 8/03, 12/03, 4/04
non illegitimi carborundum

> Steve Kramer wrote:
> "Good?  That's fantastic.  There isn't another brachy patient here with a
[quoted text clipped - 14 lines]
> level out near 0.1, and approx 1/3 at undetectable.
> Paul Ketterer
Larry - 08 Aug 2004 22:43 GMT
Hi Paul,

That's REALLY good! No HT so I assume you're living a "normal" life? Of
course, my situation is different given the lymph node invasion. My
urologist was recommending RRP up until my lymph node dissection. Then the
discussion turned to, in his terms, "a more aggressive approach". Then, he
immediately started the HT and brought Dr. Blasko into the picture. The rest
is history.
I think I'll raise a toast (Guinness, of course) in your honor! (as if I
need an excuse <g>)

Larry

PS Had a great workout this morning. Yard work this afternoon - would rather
do something fun. Oh well.

> Steve Kramer wrote:
> "Good?  That's fantastic.  There isn't another brachy patient here with a
[quoted text clipped - 14 lines]
> level out near 0.1, and approx 1/3 at undetectable.
> Paul Ketterer
Beverley - 09 Aug 2004 03:28 GMT
That is fantastic!!! Now I can't wait to see where my husband's PSA falls
this Sept. You are almost one year to date ahead of my husband. At 16 months
he was 0.18 at 22 months my husband was 0.15 so maybe it will drop to <.1

Oh, the waiting! Doesn't matter what treatment you have the wait is always
going to be there.
Bev

> Steve Kramer wrote:
> "Good?  That's fantastic.  There isn't another brachy patient here with a
[quoted text clipped - 14 lines]
> level out near 0.1, and approx 1/3 at undetectable.
> Paul Ketterer
Alan Meyer - 10 Aug 2004 04:00 GMT
> That is fantastic!!! Now I can't wait to see where my husband's PSA falls
> this Sept. You are almost one year to date ahead of my husband. At 16 months
[quoted text clipped - 3 lines]
> going to be there.
> Bev

Bev,

I have read two standards for success on radiation patients,
.4, and .2.  By either standard, it sounds like your husband has
already made it into the winner's circle.  Any more is just icing
on the cake.

But then a little icing never hurts when you can get it.

   Alan
Beverley - 10 Aug 2004 13:52 GMT
Alan if there is a chance that his PSA would drop into the undetectable
range - I'll take it. There is no such thing has having your PSA too low.
(Of course you know I'm going to freak the first time it wobbles up even the
tiniest bit!)
Bev

> > That is fantastic!!! Now I can't wait to see where my husband's
> PSA falls
[quoted text clipped - 18 lines]
>
>     Alan
Paket41 - 15 Aug 2004 18:52 GMT
Bev,
My urologist, who works as a team with my Rad Onc, told me on my visit to him
after my first post seeding PSA, that about 20% of their patients experience a
"bump" in PSA, at an avg of 18-24 months post seeding.  He also said that these
patients continue to see a drop in PSA after the bump.  (These two doctors had
performed seeding on about 900 patients over 7 years at the time I was
treated.)

When I asked how long it might take for my PSA to reach ND, if it were to
happen, he said anywhere from 2 years to as long as 4 years.  He said they had
1 patient who hovered near 1.0 for over 3 years, and then suddenly dropped to
ND at 4 years.  He could not explain why that happened.

Hang in there, It looks like your husband has a good chance of leveling out at
0.1 or less.
Paul
 
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