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Medical Forum / Diseases and Disorders / Prostate Cancer / August 2004update - psa post seeds
Well, my first PSA since my seed implants on June 10th: PSA on 8/5/04: 0.1 Complex PSA: 0.10 (opposite of free psa) (that's good) :-) Historical perspective: Initial PSA resulting from routine physical on 5/12/03: 14.4 age at diagnosis: 60 first biopsy, negative second biopsy one positive core Gleason 3+4 started Zoladex 2/5/04, follow-up injections on 5/5/04 and 8/5/04 Lymphnode biopsy: positive in one node bone scan clean grade t1cm0n1 psa: 4/6/04 1.5 psa: 5/5/04 0.8 completed five weeks Four Field EBRT 5/14/04 PD-103 seeds 6/10/04 I have some comments to make on the hormone portion of my treatments that I will share on the "information on hormone therapy" thread that I have been lurking intently. Thanks Alan for the great post. I share some of the same concerns and issues. Larry > Well, my first PSA since my seed implants on June 10th: > PSA on 8/5/04: 0.1 > Complex PSA: 0.10 (opposite of free psa) > > (that's good) :-) Good? That's fantastic. There isn't another brachy patient here with a 0.10 PSA. I don't think there is a 0.10 PSA here among any ratiation treatment of any kind! Excellent!!!!!!!!!  SignatureProstate Cancer Survivor (so far), not a doctor PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Erection 05/12/2003 @ 48 HTbegins 07/21/2003 @ 48 PSA .07 .05 Lupron 7/03, 8/03, 12/03, 4/04 non illegitimi carborundum Hi Steve, Interesting. I had no idea how I fit in statistically at this point. Thanks for the insight. Of course, how I do over time is what's important but for now, I'll take the victory. Now, to work on my sex drive and get peeing frequency to improve . . . . > > Well, my first PSA since my seed implants on June 10th: > > PSA on 8/5/04: 0.1 [quoted text clipped - 5 lines] > 0.10 PSA. I don't think there is a 0.10 PSA here among any ratiation > treatment of any kind! Excellent!!!!!!!!! When I had salvage radiation (EBRT), my PSA went down to 0.15 before going up. But, at the time, my onc and uro both told me as long as it goes down to some level and stays there for 30 years, I should be O.K. It sounds like you just might make that qualifier. SignatureProstate Cancer Survivor (so far), not a doctor PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Erection 05/12/2003 @ 48 HTbegins 07/21/2003 @ 48 PSA .07 .05 Lupron 7/03, 8/03, 12/03, 4/04 non illegitimi carborundum > Hi Steve, > Interesting. I had no idea how I fit in statistically at this point. Thanks [quoted text clipped - 12 lines] > > 0.10 PSA. I don't think there is a 0.10 PSA here among any ratiation > > treatment of any kind! Excellent!!!!!!!!! > > Well, my first PSA since my seed implants on June 10th: > > PSA on 8/5/04: 0.1 [quoted text clipped - 5 lines] > 0.10 PSA. I don't think there is a 0.10 PSA here among any ratiation > treatment of any kind! Excellent!!!!!!!!! Steve, It is an excellent reading, but Larry is also on Zoladex, which will hold the PSA low. I had 4 months of Lupron, with radiation in the middle of it. My PSA readings were undetectable at one month, still undetectable at three months, and 0.8 at six months. As you can imagine, my first thought was that the treatment had failed. But the doctor assured me that my two undetectables were artificially low due to the Lupron, and the .8 was "normal and expected for 6 months post radiation. I really won't know if the treatment worked for many months yet, possibly not for a few years. Larry, It is very likely that your PSA will go up some time (not immediately) after the Zoladex wears off. Don't be overly alarmed by that. It is "normal and expected". Alan > It is an excellent reading, but Larry is also on Zoladex, > which will hold the PSA low. Oh, sh.t! Sorry, Larry. I should pay better attention. Still, 0.1 is 0.1. SignatureProstate Cancer Survivor (so far), not a doctor PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Erection 05/12/2003 @ 48 HTbegins 07/21/2003 @ 48 PSA .07 .05 Lupron 7/03, 8/03, 12/03, 4/04 non illegitimi carborundum > Well, my first PSA since my seed implants on June 10th: > PSA on 8/5/04: 0.1 [quoted text clipped - 23 lines] > > Larry Larry, Congratulations on the low PSA, I wonder if the PSA testing while on Zolodex will yield valid results of the brachytherapy. I've been on Lupron since last Nov. and will continue for a couple of months more. I had 83 Pd 103 seeds implanted on June 2 and both the urologist and brachytherapist feel that any PSA testing until after the Lupron is out of my system would be eroneous, as the Lupron is not being used as a palliative treatment, but as an adjuvant theraphy. Tom I agree with Alan that the Zoladex is helping to give you the lower PSA. Hubby is 2 years out from EBRT and seeds and his is 0.15 so it's almost as low. But my husband has had no HT so his PSA has just slowly fallen. Just remember after the Zoladex wears off the aim is for anything under 0.2 Bev > Well, my first PSA since my seed implants on June 10th: > PSA on 8/5/04: 0.1 [quoted text clipped - 23 lines] > > Larry Thanks All, All very valid observations. Especially in light of the fact that my PSA dropped to .8 before my EBRT and seeds just on the strength of the Zoladex alone. Also, a low PSA will be achieved by men who have only the HT such as those who have mets to the bones and are buying time. I'll still take it <g> > I agree with Alan that the Zoladex is helping to give you the lower PSA. > Hubby is 2 years out from EBRT and seeds and his is 0.15 so it's almost as [quoted text clipped - 30 lines] > > > > Larry Look at it this way at least it is hormone receptive and I think that is very positive!! Because if it wasn't then (probably) it would never have fallen that low. If you were a 3.0 then you might have had more to worry about. I think as the HT wears off you are apt to see a little wiggle in the numbers but don't forget you just starved a whole lot of cancer cells to death! Bev > Thanks All, > All very valid observations. Especially in light of the fact that my PSA [quoted text clipped - 41 lines] > > > > > > Larry Bev, you're a gem!!! Thanks for just the right thing to say. For some reason I can't explain, I've been in a real funk today. You would think good news would have a positive effect but it's been just the opposite. Your post helped a lot - why I can't explain either <g> Thanks, Larry > Look at it this way at least it is hormone receptive and I think that is > very positive!! Because if it wasn't then (probably) it would never have [quoted text clipped - 52 lines] > > > > > > > > Larry > Bev, you're a gem!!! > [quoted text clipped - 5 lines] > Thanks, > Larry Larry, Have a look at the posting below by Curtis named: "Combining Radiation Modalities Increases Prostate Cancer Cure Rates". The therapy you had is looking very good on cure rates. It's basically the same therapy I had (though mine used HDR brachytherapy instead of Palladium seeds) for a very similar case (Gleason 4+3). I'm encouraged by the findings. They look good for both of us. Alan |
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