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Medical Forum / Diseases and Disorders / Prostate Cancer / June 2004

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The Joy Continues!

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Danny McCarty - 22 Jun 2004 21:43 GMT
Short history for new patients;  I was diagnosed in January, 2001, had a
Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a month
later, higher than the PSA at diagnosis, and started Casodex to shrink gland
for radiation. When PSA was 0.5 in October, entered course of 37 radiation
treatments.  PSA was 1.1 at end of radiation and started rising in the fall of
2002, when I began injecting leukine.  After about six months I started taking
thalidomide, too.  Summer of 2003 PSA jumped to 35 and doc jerked me off
leukine and thalidomide, prepared me for chemotherapy.  After 24 weeks of
chemotherapy my PSA was 12, two months ago.  I lost my hair, but it is growing
back.  I am now on daily Casodex, with Lupron injections every three months.

  Now the update.  Latest CAT scan and x-rays are CLEAR.  Latest PSA (12) and
bone scan are the SAME as three months ago.  A blood enzyme that is usually
elevated when there is cancer in the bone is right in the middle of the NORMAL
range.  Doc still has the yellow flag up, after that weird PSA jump to 45 four
months ago, but expects the PSA to go down.  He suspects the high PSA came from
cancer cells bursting and dumping it into the bloodstream. Blood draws for PSA
and testosterone continue every six weeks for the rest of the year.  
If PSA stays the same or drops, it will probably be another three years before
it starts rising again and I have to do chemotherapy again.
olfart - 22 Jun 2004 22:24 GMT
> Short history for new patients;  I was diagnosed in January, 2001, had a
> Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a month
[quoted text clipped - 16 lines]
> If PSA stays the same or drops, it will probably be another three years before
> it starts rising again and I have to do chemotherapy again.

Great news Danny. You're a fighter and the good results are proof of that.
Hope the good news continues.
I have one question concerning PSA readings while on Lupron. I just finished
42 IMRT and have been on Lupron since December. I will continue Lupron for
at least another year.  When I asked how my RadOnc would be able to monitor
the results of my Radiation treatments I was told that as long as I am on
Lupron that PSA testing would not give reliable results and that I would be
monitored with scans, etc. I have seen a few others post PSA while on Lupron
so this is very confusing.
Any light you can shed on this would be appreciated.
George
Age - 69
8/12/02 - PSA 3.7
10/13/03 - PSA 4.69
11/11/03 - PSA 4.8
11/18/03 - Biopsy - 10 cores
one core-25% of core-Gleason 4+4=8
all other cores benign tissue
12/10/03 - Consult - Oncologist MD
12/16/03 - Consult - Radiation Oncologist
Treatment Plan - Northeast Ga Cancer Center
HT - started 12/17/03 - Eulixen & Lupron (2nd 4 mo Lupron-4/26)
2/10/04 - Started - Flowmax and Megastrol
Radiation - IMRT to begin 3/30/04 - 42 treatments - Completed 6/8/04
Danny McCarty - 23 Jun 2004 22:19 GMT
>Subject: Re: The Joy Continues!
>From: "olfart" olfart65@excite.com
>Date: 6/22/2004 4:24 PM Central Daylight Time
>Message-id: <2jrmd2F1331gfU1@uni-berlin.de>

Thanks, all!!  I'm just sticking to the program, the doc deserves all the
praise.  He really gushes over these results- that PSA of 45 so long ago now
puts me in a class all by myself, he says- everyone else's PSA goes down
immediately.  I will join the gang next year.

George,
     The Lupron usually drops the PSA down to something on the order of 1.0
but it doesn't kill the cell, just stops it from growing.  Radiation does kill
the cell, but the only evidence we have for how well it is working is PSA and
scans. After the Lupron has neutralized the production of PSA, its reduction is
not evidence of cell death anymore.  Saw Palmetto does the same, but doesn't
even stop cancer cell growth- it just "tells" you the cancer is slowed down
when it is actually raging ahead.  CAT scans and bone scans are most
dependable, but expensive.

>> Short history for new patients;  I was diagnosed in January, 2001, had a
>> Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a
[quoted text clipped - 54 lines]
>2/10/04 - Started - Flowmax and Megastrol
>Radiation - IMRT to begin 3/30/04 - 42 treatments - Completed 6/8/04
olfart - 23 Jun 2004 22:39 GMT
> >Subject: Re: The Joy Continues!
> >From: "olfart" olfart65@excite.com
[quoted text clipped - 15 lines]
> when it is actually raging ahead.  CAT scans and bone scans are most
> dependable, but expensive.

Thanks Danny
Steve Kramer - 23 Jun 2004 02:27 GMT
That is absolutely amazing Danny.  Thank you for keep us up to date.

Signature

Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Erection 05/12/2003 @ 48
HTbegins 07/21/2003 @ 48
PSA  .07 .05
Lupron 7/03, 8/03, 12/03, 4/04

> Short history for new patients;  I was diagnosed in January, 2001, had a
> Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a month
[quoted text clipped - 16 lines]
> If PSA stays the same or drops, it will probably be another three years before
> it starts rising again and I have to do chemotherapy again.
Dave P - 23 Jun 2004 02:57 GMT
Great - Fantastic news Danny. Your winning this game.

If your PSA drops or stays the same and it is another 3 years before it
rises - I believe there will be a few different treatments by then, other
than chemo that will most likely be more effective.

Hang in there and keep fighting.

Dave P

> Short history for new patients;  I was diagnosed in January, 2001, had a
> Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a month
[quoted text clipped - 16 lines]
> If PSA stays the same or drops, it will probably be another three years before
> it starts rising again and I have to do chemotherapy again.
John Loomis - 23 Jun 2004 03:42 GMT
Hi Danny!

You deserve a medal!
Keep the fight up.  We are all in similiar boats so to speak, and your boat
is doing fine!
Keep us posted, and keep fighting.
I am a fighter, and had RP in 1999.
Yep been there and still doing it?
Understand.
John Loomis
> Short history for new patients;  I was diagnosed in January, 2001, had a
> Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a month
[quoted text clipped - 16 lines]
> If PSA stays the same or drops, it will probably be another three years before
> it starts rising again and I have to do chemotherapy again.
ButtercupsDad@dog.net - 23 Jun 2004 12:53 GMT
Great news Danny.  I wish you continued success in your battle with
this beast.   You are an inspiration to those who are faced with the
same fight.  God bless you.

David S.

>   Now the update.  Latest CAT scan and x-rays are CLEAR.  Latest PSA (12) and
>bone scan are the SAME as three months ago.  A blood enzyme that is usually
[quoted text clipped - 5 lines]
>If PSA stays the same or drops, it will probably be another three years before
>it starts rising again and I have to do chemotherapy again.
Beverley - 23 Jun 2004 18:37 GMT
You've been so lucky battling this demon. I think the aggressiveness of your
doctor and your attitude have made all the difference in the world. Keep it
up - you're setting a baseline for so many more to follow. Keeping my
fingers crossed for continued good results.
Bev

> Short history for new patients;  I was diagnosed in January, 2001, had a
> Radical Retropubic Prostatectomy on 25 April 2001, had a PSA of 12.4 a month
[quoted text clipped - 16 lines]
> If PSA stays the same or drops, it will probably be another three years before
> it starts rising again and I have to do chemotherapy again.
 
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