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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2004

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extreme fatigue

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Lorelei - 29 May 2004 15:11 GMT
Hi all,
I am posting from work so my sig is not there. those who know of Curt
and me know the deal.
Last evening curt told me (again) that his fatigue is overwhelming!!
He told me this about 2-3 wks ago and the Onocologist said to him "You
look GREAT!!"
well, he doesn't feel great. He says that he is putting a lot of
energy into trying to seem like himself and keep up appearances but it
isn't working anymore. It seems like the Doctor is in denial of how
sick Curt is?..?
I am going to call them but I am sure they are closed on Monday and
the nurse if off on Tuesday so nothing until Wednesday. He is eating
and taking a vitamin. he isn't losing any weight. In fact, he is up a
few lbs from last month.

He told me last night that he thinks "this is the beginning of the
end"!!!!!!

I am researching ways to combat fatigue. any suggestions?
TIA
Lori
MH - 29 May 2004 17:26 GMT
Hi, Lori,
The only way to really find out if something else is causing Curt's fatigue
is to have some tests done, I suppose.  But the following are things I have
heard of people using to combat fatigue.

First of all, could it be that he is anemic due to the drugs he has been
given.  If so, his iron could be low.... and vitamins with iron might help
that.

Secondly, I have heard of people using ginseng or Ginsana or some other
product containing ginseng to help with fatigue.  I've never tried it
myself, as I get hyper when I have too much caffeine, so no telling what
ginseng would do to my system.  But I understand it works for some people.

Lastly, depression can cause extreme fatigue.  With all that Curt is going
through, is it possible that he is battling depression and doesn't even
realize it? Have you noticed a change in his mood lately?  Depression would
be *VERY* understandable.... and even *expected*... in this kind of
situation.  His statement that he feels like this is *the beginning of the
end* makes me wonder if that might be a contributing factor.  If so, perhaps
he needs to see someone for treatment with anti-depressants.  Many of us
here have used them.  I have used them off and on for a long time.... long
before PCa.  Maybe he just needs something to help him with this.

Please know that these are just ideas.  I wish I knew what to tell you that
would work for sure.  I hope that sharing these thoughts will help.... or at
least, perhaps, give you food for thought and perhaps help you come up with
something else.
I wish you well!

MikeH

> Hi all,
> I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 17 lines]
> TIA
> Lori
Alan Meyer - 31 May 2004 05:05 GMT
> Hi, Lori,
> The only way to really find out if something else is causing Curt's fatigue
[quoted text clipped - 4 lines]
> given.  If so, his iron could be low.... and vitamins with iron might help
> that.
...

I'm no doctor, but both of those points seem very
relevant to me.  Although it's certainly true that
depression can cause fatigue, neither counseling
nor anti-depressants can counter anemia or some
other bio-chemical deficiency.  It would be very
frustrating to go through counseling and anti-depressant
medication if the real problem is biochemical.

Taking supplements may help, but may also mask
the problem in blood tests.  I like the idea of taking
supplements, but wonder if it's possible to get hold
of a doctor to find out whether it's a good idea, and
whether it's possible to get a full set of blood tests
ASAP so he can find out what supplements he might
need - if any.

It is surprising, but true, that a tiny amount of some
chemical, whether too much or too little, can make
an extraordinary difference in your quality of life.  Ask
anyone who's had a thyroid condition, a diabetic
condition, or any of a hundred other similar problems.
These problems can make you feel like death is
right around the corner but sometimes turn out to be very
easy to treat.

Tell Curt to hang on while you get this investigated,
and also tell him that everyone on this newsgroup is
rooting hard for him to pull through this.

Both of you are in our thoughts.

Best of luck to you both.

   Alan
Lorelei - 31 May 2004 16:55 GMT
thank you
> > Hi, Lori,
> > The only way to really find out if something else is causing
[quoted text clipped - 44 lines]
>
>     Alan
Lorelei - 31 May 2004 16:55 GMT
> Hi, Lori,
> The only way to really find out if something else is causing Curt's fatigue
[quoted text clipped - 4 lines]
> given.  If so, his iron could be low.... and vitamins with iron might help
> that.

He is on the low end of normal for rbc and hematocrit

> Secondly, I have heard of people using ginseng or Ginsana or some other
> product containing ginseng to help with fatigue.  I've never tried it
[quoted text clipped - 10 lines]
> here have used them.  I have used them off and on for a long time.... long
> before PCa.  Maybe he just needs something to help him with this.

He was on Zyban for the first month or so to quit smoking and then stopped.
He was given Paxil 2 months ago but quit taking it because it had sexual
side effects and that really isn't a problem for us. I keep talking about
depression. (hell, I had to add a med to keep sane since this has all
happened. Prozac and now Wellbutrin too)

> Please know that these are just ideas.  I wish I knew what to tell you that
> would work for sure.  I hope that sharing these thoughts will help.... or at
[quoted text clipped - 3 lines]
>
> MikeH

Thanks Mike, a bit of an update, Curt took 2 Vicodin Saturday evening and
then was feeling better (his pin-prickly bone pain was back again :(
and then again on Sunday he took 2 in the morning. He had been taking 2 in
the morning before work and 2 in the evening but was "worried" about taking
so much. the doc keeps saying to not worry about pain meds.
We will see, he is at a golf tournament this morning and I am meeting him at
the Club at noon. I was going to go pull his cart for him (too wet here in
MN to drive the cart on the fairways) but I was so tired from working the
weekend and S4 had another nosebleed this morning at 0630 so I stayed home
with him.

Thanks for all your suggestions. this NG has been so helpful to me.

Signature

Lori
Devoted wife of Curtis, Stage 4 Prostate cancer at age 40
PSA 865    Dec 30,2003
         44     Feb  23,2004
         17.3  Mar 15,2004
         18.9 Apr 16, 2004
          17.3 May 14, 2004
mets to bone and lymph
Lupron Q3months
Casodex 50 mg daily
Zometa inf. qmonth
http://community.webshots.com/user/lorismiller-date

c palmer - 29 May 2004 18:07 GMT
hi lori - i agree with mike - depression does that it's toll on you.

each person that takes lupron responds differently.  and fatigue is one
of things that can happen.

i feel that it is a temp. thing.  after the body adjusts to everything,
the energy level will come back.  

tell curt it is not the beginning of the end.  that is when the psa
starts climbing back up and you can't stop it.  so, that's not happening
and therefore, it is not the beginning to end.

however, the feeling he has could be overwhelming and attitude is
everything.  as you've pointed out.  maybe the extra herbs and vitamins
will ease this symptom faster.  it's certainly worth a look at.

~ curtis

knowledge is power - growing old is mandatory - growing wise is optional    
"Many more men die with prostate cancer than of it. Growing old is
invariably fatal. Prostate cancer is only sometimes so."
David  S. - 29 May 2004 19:32 GMT
   Does he exercise regularly, or at least go for long walks?  Has his
sleep pattern been interrupted by everything else that is going on with him?
Have you checked to see if fatigue is a normal side effect of the Lupron?
If you have a primary care doctor you may ask if he would run some routine
blood tests to see if there is something there that is causing the fatigue.
I battle fatigue, so I can understand some of what your husband is facing at
least with that.  In my case I think it is a combination of being
overweight, out of shape, worry, and stress at work, so there is no magic
pill to fix me up.
   The extreme fatigue is not normal, so I would keep investigating, make
some noise, and get some answers.  I would also not ignore the comment about
"the beginning of the end".  Is there a reason you are the one on the ng and
not him?  Maybe he needs to do some talking directly to people who have in
the past, or who are now, going through the same thing.
   Good luck to you.  Remember to take care of yourself too.
   Thank you.
David S.

> Hi all,
> I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 17 lines]
> TIA
> Lori
alioop 9 - 29 May 2004 20:06 GMT
Hubby had his last radiation treatment (42) May 5.  He too suffers from
extreme fatigue.  He has other physical problems and insomnia is an old
friend.  Basically, when he is tired, I let him sleep as long as he
wants and encourage him to nap if needed during the day.  The radiation
caused him to become anemic (or we guess that's what caused it), so that
contributes to the fatigue.

The good news is that I can see quite a bit of improvement in the last
week or so.  We can go to the grocery store, put the food away and he
doesn't have to go lay down.  He is still  pale and will get dark
circles under his eyes when he is tired, but I am encouraged by his
increased stamina.  Tell your husband "this too shall pass" and to take
it easy until he feels ready to take on more activity.
Lorelei - 31 May 2004 17:00 GMT
>     Does he exercise regularly, or at least go for long walks?

He has a physical job (flooring) probably too strenuous plus he is a driven
person and doesn't like to slow down. and I have brought up the idea of
evening walks. I will keep working at this.

> Has his sleep pattern been interrupted by everything else that is going on
with him?

He is sleeping better than he has for awhile.

> Have you checked to see if fatigue is a normal side effect of the Lupron?
it is.
> If you have a primary care doctor you may ask if he would run some routine
> blood tests to see if there is something there that is causing the fatigue.

He doesn't want a primary care physician. I know..

> I battle fatigue, so I can understand some of what your husband is facing at
> least with that.  In my case I think it is a combination of being
[quoted text clipped - 4 lines]
> "the beginning of the end".  Is there a reason you are the one on the ng and
> not him?

Yes, it has basically become my job to research and I come here for myself
more than for him. In fact, I am the one who calls the nurse and does most
of the talking to the doctor. Last time we were there and Curt said he was
Fatigued the doctor keep pushing Viagra!!

> Maybe he needs to do some talking directly to people who have in
> the past, or who are now, going through the same thing.

I wish he would. I do put many of the relevant posts in folder and print
them out for him to read.

>     Good luck to you.  Remember to take care of yourself too.
>     Thank you.
> David S.

Thanks. you too.

Signature

Lori
Devoted wife of Curtis, Stage 4 Prostate cancer at age 40
PSA 865    Dec 30,2003
         44     Feb  23,2004
         17.3  Mar 15,2004
         18.9 Apr 16, 2004
          17.3 May 14, 2004
mets to bone and lymph
Lupron Q3months
Casodex 50 mg daily
Zometa inf. qmonth
http://community.webshots.com/user/lorismiller-date

Steve Kramer - 29 May 2004 23:56 GMT
Lori,

The following is my opinion, based on experience, not medical training:

If he thinks it is the beginning of the end, it probably is.  Not because it
has to be, but because he thinks it is.  The fatigue is probably not a
symptom of prostate cancer, but that of the medications he is taking, or
depression.  Pain is a better indicator of 'the end' and PSA is a better
indicator still.  His PSA is down dramatically from 865.  He is not as close
to 'the end' as he was January 16th.

He is probably suffering from depression.  He has every right to be
depressed and that makes it harder to get him out of it.

When I was fatigued from radiation (and I was probably not as bad as he), I
walked a lot, drank copious amounts of coffee, and I worked out a little.
You need to convince him to get his endorphins going through positive stress
or ustress (sp?).  But, it probably won't be easy.

Signature

Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000
PSA  .1  .1  .1  .27  .37  .75
EBRT 05-07/2002 @ 47
PSA  .34 .22 .15 .21 .32
Erection 05/12/2003 @ 48
HTbegins 07/21/2003 @ 48
PSA  .07 .05
Lupron 7/03, 8/03, 12/03, 4/04

> Hi all,
> I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 17 lines]
> TIA
> Lori
Dennis & Bonnie French - 30 May 2004 00:13 GMT
Would he ever consider going for counseling? Maybe he needs to speak to a
professional about his condition and the whole situation. It may not relieve
the fatigue, but he may be able to cope with everything better. Just a
thought since I know that both Dennis and I were depressed over his
diagnosis last year, and not all medical doctors take the time to listen to
everything.
Best wishes to you both.
Bonnie
> Lori,
>
[quoted text clipped - 36 lines]
> > TIA
> > Lori
Danny McCarty - 30 May 2004 21:06 GMT
>Subject: Re: extreme fatigue
>From: "Dennis & Bonnie French" TheFrenchConnection@gbronline.com
[quoted text clipped - 53 lines]
>> > TIA
>> > Lori

I was diagonosed with "moderate to severe depression" with a prognosis of
"guarded at best", fifeteen years ago.  The doc thought it likely I would
attempt suicide.  I felt no inclination to commit suicide.  I had myalgic
encephelopathy and situational depression, and toughed it out.  A mild
antidepressant -can/might- relieve the fatigue.  Radiation can reduce red blood
cell count and cause depression.  An energy drink could help by replacing iron
and B12.  Mild exercise can help.

Jan. 5, 2001,  PSA 5.2
Jan 10, 2001, PSA 10.4 (different lab).
Feb 20, 2001, cancer in 6 of 8 cores, Gleason 4 + 3 = 7
Apr. 25, 2001, a few PCa cells in seminal vesical, none in lymph nodes, margins
clear. Gleason 8 (9?).
Jul 9, 2001, PSA 10.5, began Casodex & Proscar.
Oct 10 to Dec 25, 2001, external beam radiation.
Jan 5, 2002, PSA 1.1
Jun 10, 2002, PSA 10.7, began Leukine injections.
Dec 12, 2002, PSA 12.5, added thalidomide tablets.
Aug 15, 2003, PSA 34.5, first Lupron injection.
Oct 17, 2003, began 24 week chemotherapy regime.
Dec 6, 2003, PSA 23.2
Feb 3, 2004, PSA 34.5, bone scan improved.
Feb 14, 2004, PSA 10.5
Feb 29, 2004, PSA 32.1
Mar 13, 2004, PSA 11.2, bone scan better than 3 Feb.
May 5  PSA 12.0  Doc is pleased.

A PURE Democracy is the Worst Possible form of government.
Larry - 31 May 2004 13:32 GMT
re:
>  A mild
> antidepressant -can/might- relieve the fatigue.  Radiation can reduce red blood
> cell count and cause depression.  An energy drink could help by replacing iron
> and B12.  Mild exercise can help.

I agree wholeheartedly. Try to encourage him to get in some exercise, even
if it's just a short walk.
It seems like a blood draw might be in order to check for anemia. Or just
try a supplement as Danny suggests.

Good luck we are all pulling for the both of you,

Larry
J - 30 May 2004 00:46 GMT
> Hi all,
> I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 17 lines]
> TIA
> Lori

http://www.cancerbacup.org.uk/Treatments/Hormonaltherapies/Individualhormonalthe
rapies/Bicalutamide


Casodex - Occasionally bicalutamide may cause feelings of weakness and
drowsiness."

If he takes it in the morning, is he allowed to try taking it at night
instead? (to see if that would make a difference).
J
Lorelei - 31 May 2004 17:03 GMT
> > Hi all,
> > I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 17 lines]
> > TIA
> > Lori

http://www.cancerbacup.org.uk/Treatments/Hormonaltherapies/Individualhormonalthe
rapies/Bicalutamide


> Casodex - Occasionally bicalutamide may cause feelings of weakness and
> drowsiness."
>
> If he takes it in the morning, is he allowed to try taking it at night
> instead? (to see if that would make a difference).
> J

I will ask Dr Londer this on wednesday. thanks for the sugg.
philski - 30 May 2004 03:33 GMT
> Hi all,
> I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 17 lines]
> TIA
> Lori
Lori,
One other thing that may have absolutely nothing to do with his fatigue
but thought I might help cover all the bases. How is his sleep patterns?
Does he snore a lot? Does he have even mild sleep apnea? All these
things can contribute to being fatigued as well as heart problems and a
host of other maladies (none of which are significant when you have
PCa). My wife has sleep apnea to some degree. It contributes heavily to
her having Restless Leg Syndrome and she is to undergo a sleep lab in
July to evaluate her condition. So, it got me to thinking that maybe
your Curt may not be getting near the sleep he needs to recharge already
depleted "batteries".

Hope everything works out for the better. BTW my better half is on Paxil
(as well as a lot of other meds) to help her combat mild depression.

Phil

(aka Philski)
Sandy - 31 May 2004 02:08 GMT
> > Hi all,
> > I am posting from work so my sig is not there. those who know of Curt
[quoted text clipped - 13 lines]
> > He told me last night that he thinks "this is the beginning of the
> > end"!!!!!!


Lori,

My husband also is experiencing severe fatigue while on the hormones.
It does seem to help to take the vitamins, try to walk, etc. but the
fatigue is still present.  In addition to r/o anemia or any other
medical problems, I also feel a consult with a counselor would be in
order.  After my husband was diagnosed a year ago, we were faced with
many issues which was not only depressing us but creating conflict
between us so I made an appointment for both of us to go see a
counselor.  At first my husband wasn't too thrilled about going but in
the end he asked if he could go alone and talk to the counselor.  I
think it was very beneficial to have that nonbiased third party. I
deal with this dilemma by engulfing myself into as much information as
I can.  I have no problem talking to anyone and everyone who will
listen to me "vent" about this ugly disease. Sometimes I think my
husband is in denial. My husband tells everyone that he is "fine" so
he never has the opportunity to openly discuss his fears, anxieties,
etc. with anyone but me and its like pulling teeth for me to get him
to talk.

Like you and your husband, our situation is ongoing.  We've been
through surgery, radiation and now long-term hormonal therapy knowing
all too well that we are trying to buy some extra time here.  
Unfortunately, the longer the treatments go on, the harder it is to
stay positive and focused.  You and your husband have had to digest an
awful lot of information in a very short period of time.  I think its
only normal that he would feel overwhelmed and quite possibly
depressed.

Sandi
 
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