Medical Forum / Diseases and Disorders / Prostate Cancer / May 2004
extreme fatigue
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Lorelei - 29 May 2004 15:11 GMT Hi all, I am posting from work so my sig is not there. those who know of Curt and me know the deal. Last evening curt told me (again) that his fatigue is overwhelming!! He told me this about 2-3 wks ago and the Onocologist said to him "You look GREAT!!" well, he doesn't feel great. He says that he is putting a lot of energy into trying to seem like himself and keep up appearances but it isn't working anymore. It seems like the Doctor is in denial of how sick Curt is?..? I am going to call them but I am sure they are closed on Monday and the nurse if off on Tuesday so nothing until Wednesday. He is eating and taking a vitamin. he isn't losing any weight. In fact, he is up a few lbs from last month.
He told me last night that he thinks "this is the beginning of the end"!!!!!!
I am researching ways to combat fatigue. any suggestions? TIA Lori
MH - 29 May 2004 17:26 GMT Hi, Lori, The only way to really find out if something else is causing Curt's fatigue is to have some tests done, I suppose. But the following are things I have heard of people using to combat fatigue.
First of all, could it be that he is anemic due to the drugs he has been given. If so, his iron could be low.... and vitamins with iron might help that.
Secondly, I have heard of people using ginseng or Ginsana or some other product containing ginseng to help with fatigue. I've never tried it myself, as I get hyper when I have too much caffeine, so no telling what ginseng would do to my system. But I understand it works for some people.
Lastly, depression can cause extreme fatigue. With all that Curt is going through, is it possible that he is battling depression and doesn't even realize it? Have you noticed a change in his mood lately? Depression would be *VERY* understandable.... and even *expected*... in this kind of situation. His statement that he feels like this is *the beginning of the end* makes me wonder if that might be a contributing factor. If so, perhaps he needs to see someone for treatment with anti-depressants. Many of us here have used them. I have used them off and on for a long time.... long before PCa. Maybe he just needs something to help him with this.
Please know that these are just ideas. I wish I knew what to tell you that would work for sure. I hope that sharing these thoughts will help.... or at least, perhaps, give you food for thought and perhaps help you come up with something else. I wish you well!
MikeH
> Hi all, > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 17 lines] > TIA > Lori Alan Meyer - 31 May 2004 05:05 GMT > Hi, Lori, > The only way to really find out if something else is causing Curt's fatigue [quoted text clipped - 4 lines] > given. If so, his iron could be low.... and vitamins with iron might help > that. ...
I'm no doctor, but both of those points seem very relevant to me. Although it's certainly true that depression can cause fatigue, neither counseling nor anti-depressants can counter anemia or some other bio-chemical deficiency. It would be very frustrating to go through counseling and anti-depressant medication if the real problem is biochemical.
Taking supplements may help, but may also mask the problem in blood tests. I like the idea of taking supplements, but wonder if it's possible to get hold of a doctor to find out whether it's a good idea, and whether it's possible to get a full set of blood tests ASAP so he can find out what supplements he might need - if any.
It is surprising, but true, that a tiny amount of some chemical, whether too much or too little, can make an extraordinary difference in your quality of life. Ask anyone who's had a thyroid condition, a diabetic condition, or any of a hundred other similar problems. These problems can make you feel like death is right around the corner but sometimes turn out to be very easy to treat.
Tell Curt to hang on while you get this investigated, and also tell him that everyone on this newsgroup is rooting hard for him to pull through this.
Both of you are in our thoughts.
Best of luck to you both.
Alan
Lorelei - 31 May 2004 16:55 GMT thank you
> > Hi, Lori, > > The only way to really find out if something else is causing [quoted text clipped - 44 lines] > > Alan Lorelei - 31 May 2004 16:55 GMT > Hi, Lori, > The only way to really find out if something else is causing Curt's fatigue [quoted text clipped - 4 lines] > given. If so, his iron could be low.... and vitamins with iron might help > that. He is on the low end of normal for rbc and hematocrit
> Secondly, I have heard of people using ginseng or Ginsana or some other > product containing ginseng to help with fatigue. I've never tried it [quoted text clipped - 10 lines] > here have used them. I have used them off and on for a long time.... long > before PCa. Maybe he just needs something to help him with this. He was on Zyban for the first month or so to quit smoking and then stopped. He was given Paxil 2 months ago but quit taking it because it had sexual side effects and that really isn't a problem for us. I keep talking about depression. (hell, I had to add a med to keep sane since this has all happened. Prozac and now Wellbutrin too)
> Please know that these are just ideas. I wish I knew what to tell you that > would work for sure. I hope that sharing these thoughts will help.... or at [quoted text clipped - 3 lines] > > MikeH Thanks Mike, a bit of an update, Curt took 2 Vicodin Saturday evening and then was feeling better (his pin-prickly bone pain was back again :( and then again on Sunday he took 2 in the morning. He had been taking 2 in the morning before work and 2 in the evening but was "worried" about taking so much. the doc keeps saying to not worry about pain meds. We will see, he is at a golf tournament this morning and I am meeting him at the Club at noon. I was going to go pull his cart for him (too wet here in MN to drive the cart on the fairways) but I was so tired from working the weekend and S4 had another nosebleed this morning at 0630 so I stayed home with him.
Thanks for all your suggestions. this NG has been so helpful to me.
 Signature Lori Devoted wife of Curtis, Stage 4 Prostate cancer at age 40 PSA 865 Dec 30,2003 44 Feb 23,2004 17.3 Mar 15,2004 18.9 Apr 16, 2004 17.3 May 14, 2004 mets to bone and lymph Lupron Q3months Casodex 50 mg daily Zometa inf. qmonth http://community.webshots.com/user/lorismiller-date
c palmer - 29 May 2004 18:07 GMT hi lori - i agree with mike - depression does that it's toll on you.
each person that takes lupron responds differently. and fatigue is one of things that can happen.
i feel that it is a temp. thing. after the body adjusts to everything, the energy level will come back.
tell curt it is not the beginning of the end. that is when the psa starts climbing back up and you can't stop it. so, that's not happening and therefore, it is not the beginning to end.
however, the feeling he has could be overwhelming and attitude is everything. as you've pointed out. maybe the extra herbs and vitamins will ease this symptom faster. it's certainly worth a look at.
~ curtis
knowledge is power - growing old is mandatory - growing wise is optional "Many more men die with prostate cancer than of it. Growing old is invariably fatal. Prostate cancer is only sometimes so."
David S. - 29 May 2004 19:32 GMT Does he exercise regularly, or at least go for long walks? Has his sleep pattern been interrupted by everything else that is going on with him? Have you checked to see if fatigue is a normal side effect of the Lupron? If you have a primary care doctor you may ask if he would run some routine blood tests to see if there is something there that is causing the fatigue. I battle fatigue, so I can understand some of what your husband is facing at least with that. In my case I think it is a combination of being overweight, out of shape, worry, and stress at work, so there is no magic pill to fix me up. The extreme fatigue is not normal, so I would keep investigating, make some noise, and get some answers. I would also not ignore the comment about "the beginning of the end". Is there a reason you are the one on the ng and not him? Maybe he needs to do some talking directly to people who have in the past, or who are now, going through the same thing. Good luck to you. Remember to take care of yourself too. Thank you. David S.
> Hi all, > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 17 lines] > TIA > Lori alioop 9 - 29 May 2004 20:06 GMT Hubby had his last radiation treatment (42) May 5. He too suffers from extreme fatigue. He has other physical problems and insomnia is an old friend. Basically, when he is tired, I let him sleep as long as he wants and encourage him to nap if needed during the day. The radiation caused him to become anemic (or we guess that's what caused it), so that contributes to the fatigue.
The good news is that I can see quite a bit of improvement in the last week or so. We can go to the grocery store, put the food away and he doesn't have to go lay down. He is still pale and will get dark circles under his eyes when he is tired, but I am encouraged by his increased stamina. Tell your husband "this too shall pass" and to take it easy until he feels ready to take on more activity.
Lorelei - 31 May 2004 17:00 GMT > Does he exercise regularly, or at least go for long walks? He has a physical job (flooring) probably too strenuous plus he is a driven person and doesn't like to slow down. and I have brought up the idea of evening walks. I will keep working at this.
> Has his sleep pattern been interrupted by everything else that is going on with him?
He is sleeping better than he has for awhile.
> Have you checked to see if fatigue is a normal side effect of the Lupron? it is.
> If you have a primary care doctor you may ask if he would run some routine > blood tests to see if there is something there that is causing the fatigue. He doesn't want a primary care physician. I know..
> I battle fatigue, so I can understand some of what your husband is facing at > least with that. In my case I think it is a combination of being [quoted text clipped - 4 lines] > "the beginning of the end". Is there a reason you are the one on the ng and > not him? Yes, it has basically become my job to research and I come here for myself more than for him. In fact, I am the one who calls the nurse and does most of the talking to the doctor. Last time we were there and Curt said he was Fatigued the doctor keep pushing Viagra!!
> Maybe he needs to do some talking directly to people who have in > the past, or who are now, going through the same thing. I wish he would. I do put many of the relevant posts in folder and print them out for him to read.
> Good luck to you. Remember to take care of yourself too. > Thank you. > David S. Thanks. you too.
 Signature Lori Devoted wife of Curtis, Stage 4 Prostate cancer at age 40 PSA 865 Dec 30,2003 44 Feb 23,2004 17.3 Mar 15,2004 18.9 Apr 16, 2004 17.3 May 14, 2004 mets to bone and lymph Lupron Q3months Casodex 50 mg daily Zometa inf. qmonth http://community.webshots.com/user/lorismiller-date
Steve Kramer - 29 May 2004 23:56 GMT Lori,
The following is my opinion, based on experience, not medical training:
If he thinks it is the beginning of the end, it probably is. Not because it has to be, but because he thinks it is. The fatigue is probably not a symptom of prostate cancer, but that of the medications he is taking, or depression. Pain is a better indicator of 'the end' and PSA is a better indicator still. His PSA is down dramatically from 865. He is not as close to 'the end' as he was January 16th.
He is probably suffering from depression. He has every right to be depressed and that makes it harder to get him out of it.
When I was fatigued from radiation (and I was probably not as bad as he), I walked a lot, drank copious amounts of coffee, and I worked out a little. You need to convince him to get his endorphins going through positive stress or ustress (sp?). But, it probably won't be easy.
 Signature Prostate Cancer Survivor (so far), not a doctor PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 PSA .1 .1 .1 .27 .37 .75 EBRT 05-07/2002 @ 47 PSA .34 .22 .15 .21 .32 Erection 05/12/2003 @ 48 HTbegins 07/21/2003 @ 48 PSA .07 .05 Lupron 7/03, 8/03, 12/03, 4/04
> Hi all, > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 17 lines] > TIA > Lori Dennis & Bonnie French - 30 May 2004 00:13 GMT Would he ever consider going for counseling? Maybe he needs to speak to a professional about his condition and the whole situation. It may not relieve the fatigue, but he may be able to cope with everything better. Just a thought since I know that both Dennis and I were depressed over his diagnosis last year, and not all medical doctors take the time to listen to everything. Best wishes to you both. Bonnie
> Lori, > [quoted text clipped - 36 lines] > > TIA > > Lori Danny McCarty - 30 May 2004 21:06 GMT >Subject: Re: extreme fatigue >From: "Dennis & Bonnie French" TheFrenchConnection@gbronline.com [quoted text clipped - 53 lines] >> > TIA >> > Lori I was diagonosed with "moderate to severe depression" with a prognosis of "guarded at best", fifeteen years ago. The doc thought it likely I would attempt suicide. I felt no inclination to commit suicide. I had myalgic encephelopathy and situational depression, and toughed it out. A mild antidepressant -can/might- relieve the fatigue. Radiation can reduce red blood cell count and cause depression. An energy drink could help by replacing iron and B12. Mild exercise can help.
Jan. 5, 2001, PSA 5.2 Jan 10, 2001, PSA 10.4 (different lab). Feb 20, 2001, cancer in 6 of 8 cores, Gleason 4 + 3 = 7 Apr. 25, 2001, a few PCa cells in seminal vesical, none in lymph nodes, margins clear. Gleason 8 (9?). Jul 9, 2001, PSA 10.5, began Casodex & Proscar. Oct 10 to Dec 25, 2001, external beam radiation. Jan 5, 2002, PSA 1.1 Jun 10, 2002, PSA 10.7, began Leukine injections. Dec 12, 2002, PSA 12.5, added thalidomide tablets. Aug 15, 2003, PSA 34.5, first Lupron injection. Oct 17, 2003, began 24 week chemotherapy regime. Dec 6, 2003, PSA 23.2 Feb 3, 2004, PSA 34.5, bone scan improved. Feb 14, 2004, PSA 10.5 Feb 29, 2004, PSA 32.1 Mar 13, 2004, PSA 11.2, bone scan better than 3 Feb. May 5 PSA 12.0 Doc is pleased.
A PURE Democracy is the Worst Possible form of government.
Larry - 31 May 2004 13:32 GMT re:
> A mild > antidepressant -can/might- relieve the fatigue. Radiation can reduce red blood > cell count and cause depression. An energy drink could help by replacing iron > and B12. Mild exercise can help. I agree wholeheartedly. Try to encourage him to get in some exercise, even if it's just a short walk. It seems like a blood draw might be in order to check for anemia. Or just try a supplement as Danny suggests.
Good luck we are all pulling for the both of you,
Larry
J - 30 May 2004 00:46 GMT > Hi all, > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 17 lines] > TIA > Lori http://www.cancerbacup.org.uk/Treatments/Hormonaltherapies/Individualhormonalthe rapies/Bicalutamide
Casodex - Occasionally bicalutamide may cause feelings of weakness and drowsiness."
If he takes it in the morning, is he allowed to try taking it at night instead? (to see if that would make a difference). J
Lorelei - 31 May 2004 17:03 GMT > > Hi all, > > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 17 lines] > > TIA > > Lori http://www.cancerbacup.org.uk/Treatments/Hormonaltherapies/Individualhormonalthe rapies/Bicalutamide
> Casodex - Occasionally bicalutamide may cause feelings of weakness and > drowsiness." > > If he takes it in the morning, is he allowed to try taking it at night > instead? (to see if that would make a difference). > J I will ask Dr Londer this on wednesday. thanks for the sugg.
philski - 30 May 2004 03:33 GMT > Hi all, > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 17 lines] > TIA > Lori Lori, One other thing that may have absolutely nothing to do with his fatigue but thought I might help cover all the bases. How is his sleep patterns? Does he snore a lot? Does he have even mild sleep apnea? All these things can contribute to being fatigued as well as heart problems and a host of other maladies (none of which are significant when you have PCa). My wife has sleep apnea to some degree. It contributes heavily to her having Restless Leg Syndrome and she is to undergo a sleep lab in July to evaluate her condition. So, it got me to thinking that maybe your Curt may not be getting near the sleep he needs to recharge already depleted "batteries".
Hope everything works out for the better. BTW my better half is on Paxil (as well as a lot of other meds) to help her combat mild depression.
Phil
(aka Philski)
Sandy - 31 May 2004 02:08 GMT > > Hi all, > > I am posting from work so my sig is not there. those who know of Curt [quoted text clipped - 13 lines] > > He told me last night that he thinks "this is the beginning of the > > end"!!!!!! Lori,
My husband also is experiencing severe fatigue while on the hormones. It does seem to help to take the vitamins, try to walk, etc. but the fatigue is still present. In addition to r/o anemia or any other medical problems, I also feel a consult with a counselor would be in order. After my husband was diagnosed a year ago, we were faced with many issues which was not only depressing us but creating conflict between us so I made an appointment for both of us to go see a counselor. At first my husband wasn't too thrilled about going but in the end he asked if he could go alone and talk to the counselor. I think it was very beneficial to have that nonbiased third party. I deal with this dilemma by engulfing myself into as much information as I can. I have no problem talking to anyone and everyone who will listen to me "vent" about this ugly disease. Sometimes I think my husband is in denial. My husband tells everyone that he is "fine" so he never has the opportunity to openly discuss his fears, anxieties, etc. with anyone but me and its like pulling teeth for me to get him to talk.
Like you and your husband, our situation is ongoing. We've been through surgery, radiation and now long-term hormonal therapy knowing all too well that we are trying to buy some extra time here. Unfortunately, the longer the treatments go on, the harder it is to stay positive and focused. You and your husband have had to digest an awful lot of information in a very short period of time. I think its only normal that he would feel overwhelmed and quite possibly depressed.
Sandi
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