Greetings !!!!

My humble obeisance request is since this post may be quite lengthy so
please spare your time & help out. Now my Father quality of life is
disturbed enormously and I really need to do something at the
earliest.

Dec'02: -- Got severe pain in the back. In MRI scan they found out
prostate cancer and he is afflicted by severe pain. Doctor (Urologist)
suggested us for Orchiectomy. Both testicles are removed on 12/2002.
+++++++++++++++++++++++++
Jan'03: -- Urologist advised to take pills (Calutide i.e is
Bicalutamide daily 1@morning )
+++++++++++++++++++++++++
Jun'03: -- Again afflicted by severe pain. From scanned report Doctor
found out cancer spread to pelvis area & he insisted us to go for
radiation. Radiation carried out for 15 sittings [Above the buttock
area]
+++++++++++++++++++++++++
Jul'03: – For second opinion I've been to Oncologist, after go through
my Father case he suggested "Lupron Depo 3.75mg" for 6 months (From
Aug'03 to Jan'04)

PSA chart
mm/yyyy      PSA score     Reference range
08/2003     1.2          0.0 to 4.0    
09/2003        1.4          0.0 to 4.0    
10/2003     0.6          0.0 to 4.0    

11/2003        1.1          0.0 to 4.0    
12/2003     2.6          0.0 to 4.0    
01/2004     6.6        0.0 to 4.0    

02/2004     11.3          0.0 to 4.0   (Latest PSA)
+++++++++++++++++++++++++
Feb'04: - He got severe pain in both the legs below the knees. From CT
& MRI scan they found the cancer spreads to some other areas.

CTSCAN : Pelvis : LYTIC LESION INVOLVING L5 VERTEBRRAL BODY AND RIGHT
ILIAC BONE – FEATURES SUGGESTIVE OF METASTATIC DEPOSIT

MRI: CERVICAL AND DORSAL SPINE – METSTATIC AT D10 LEVELWITHIN THE
VERTEBRAL BODY – THERE IS NO CORTICAL EROSION, INTRANSPINAL EXTENSION
OR PARAVERTEBRAL SOFT TISSUE INVOLVEMENT – THE REST OF FINDINGS ARE
NORMAL

TREATMENT GIVEN FOR THE ABOVE PROBLEMS/REPORTS

1.    Ext RT : to the :3-L5 , Illiac bone – 3300cGy/300cGy/11 # (From
03/03/04 to 17/03/04)
2.    Ext RT : to the D9-D12 – 3000cGy/300cGy/10# From 14/04/04 to
27/04/04

+++++++++++++++++++++++++
May'04: - After the Nuclear bone study,MRI of LUMBAR SPINE  test they
found out its nerve compression, which causes the pain. During this
period we were used to give some pain killer injection or tablet. But
most of the times it won't help much.

Onco (RT) referred us to Neurosurgeon for this problem. I expected
that he can go for some treatments, which help out for my Father, but
unfortunately he didn't take my Father case and he give a letter back
to oncologist & here it is…

Neurosurgeon letter to Oncologist (RT)
He has clinical features of cauda equina syndrome causing bilateral
foot weakness, most prominent in the right foot dorsiflexor. In
addition he had root pain predominantly on the left side. The clinical
and imaging finding suggest root compression due to multiple
metastases but especially at L4-5 level. The disc bulge is because of
the collapse of the body. It is not like the usual case of disc
prolapse. Since the lesions are multiple, they are not amenable to
surgery. Please continue appropriate hormonal chemotherapy along with
analgesics and bed rest.

Now we all are totally weak and don't know what to do after the
neurosurgeon reply. Please advice me how to proceed in order to give
him a better quality of life.

My primary concern is how to get rid of the pain (nerve compression) ?
For the past 10days he got some other problem in the urination also,
he is badly suffering from burning feelings in the tip while the time
of urination and the color of the urine also looks light green. During
night times he is passing more urination. I don't know whether it is
because of the Cauda equina syndrome or the chemotherapy.

Right now he is taking the following things

1.    Calutide that is Bicalutamide- Daily Morning 1 Tablet
2.    Honvan (Chemo tablet) – 2 tablets @night
3.    Tablets and tonic for urination infection and for the pain/burning
feelings
4.    Once in a month zoldonet injection (3months over)

Since they said its Cauda equina syndrome, does anyone of you heard
about prostate cancer with this Cauda equina syndrome problem? Please
check with your friends/colleagues and kindly advise how I proceed
further. If possible let me know how in US they will give treatment
for this kind of patients (Advanced Ca Prostate with Cauda equina
syndrome)

Frankly speaking I don't know what to do & my life is paining if I
heard the pain news and the way he is suffering from this disease. I
am speechless to express my feelings. Please consider this as an
urgent case and help out at your best. I am ready to talk to any of
you if you want me to talk to you and give further inputs. Right now I
am in Singapore & my parents in India. If possible you please check
with US Doctors about this case or kindly help him to get rid of the
pain and give good Quality of life.

If you know any clinical trials, which is available globally kindly,
let me know. I will closely check with my Doctor and check for the
feasibility. If anyone of you or your friends/relatives affected from
the same kind of disease please let me know how you giving treatment
with the tablets/injections names. We will check whether the same
treatment or the injection/tablets available in India.

If you need any report please reply to this post or grpdocs@yahoo.com
i will post it immdly..

Thanks a lot !!!!

Best Regards
Prasath.