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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2004

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Incontinence and high blood pressure.

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David  S. - 08 May 2004 11:48 GMT
   In one of the recent posts the gentleman mentions experiencing some
leakage due to being on high blood pressure medication.  Has anyone else
experienced that, or does anyone have any insight into what one should
expect when starting medication for high blood pressure?  My internist told
me that I have high blood pressure, and I have a follow up visit in another
month or so when he will put me on medication if I have not been able to
bring it down with diet and exercise (so far no luck).  I still have
incontinence from the RRP, so I am worried that it will get worse if I do go
on blood pressure med's.
   Thank you.
David S.
olfart - 08 May 2004 13:22 GMT
>     In one of the recent posts the gentleman mentions experiencing some
> leakage due to being on high blood pressure medication.  Has anyone else
[quoted text clipped - 7 lines]
>     Thank you.
> David S.

There might be some connection I take Flowmax(2/day) to help with slow flow
problems due to Radiation. Also have high B/P and take meds for that. With
just the B/P meds my pressure stays around 140/75. When I started the
flowmax I peed better, but my B/P also drops to around 120/70 and at times
during the day I get as low as 98/60.
So it seems that I have a better urine flow with a lower B/P. I don't get to
the point of leakage, but some times it comes close.

Age - 69
8/12/02 - PSA 3.7
10/13/03 - PSA 4.69
11/11/03 - PSA 4.8
11/18/03 - Biopsy - 10 cores
one core-25% of core-Gleason 4+4=8
all other cores benign tissue
12/10/03 - Consult - Oncologist
12/16/03 - Consult - Radiation Oncologist
Treatment Plan - Northeast Ga Cancer Center
HT - started 12/17/03 - Eulixen & Lupron (2nd 4 mo Lupron-4/26)
2/10/04 - Started - Flowmax and Megastrol
Radiation - IMRT to begin 3/30/04 - 42 treatments
c palmer - 08 May 2004 15:08 GMT
hi david - i got put on high blood pressure medicine about three months
before the RP and have been on it ever since.  i'm up to about 99%
continence now at the one year mark.

i haven't heard anything about a relationship between the two subjects.
if one were to step back and look at what the purpose of the medicine,
it just allows the arteries to not constrict as much and stay open which
drops the blood pressure.  the incontinence problem is due to the muscle
having to be re-trained or damage to the valve itself.  assuming there
is no damage to the valve itself and it is strictly a muscle problem,
then i don't see where the BP would cause the valve to leak but it one
were on muscle relaxants, i could.  

hope this helps.

~ curtis

knowledge is power - growing old is mandatory - growing wise is optional    
"Many more men die with prostate cancer than of it. Growing old is
invariably fatal. Prostate cancer is only sometimes so."
Steve M. - 08 May 2004 16:35 GMT
David,
Frequently one of the first medications used for high blood pressure
is a diuretic reducing body fluid and salt retention. I take blood
pressure medication containing a diuretic and I believe it contributed
to difficulty in regaining continence and contributes to minor drips.
Coffee, tea, chocolate and most soft drinks contain caffeine, which is
a diuretic and can contribute to incontinence. I can definitively tell
when I have had too much of that. Not all BP medications contain a
diuretic.
Definitely watch your salt intake. I can tell a major difference in
the BP when I keep salt low. Also exercise and weight loss have had a
major impact for me.
Good luck with the BP control.

Steve M

> In one of the recent posts the gentleman mentions experiencing some
> leakage due to being on high blood pressure medication.  Has anyone else
[quoted text clipped - 7 lines]
>     Thank you.
> David S.
C. Paul Williams, MD - 08 May 2004 17:54 GMT
> In one of the recent posts the gentleman mentions experiencing some
> leakage due to being on high blood pressure medication.  Has anyone else
[quoted text clipped - 7 lines]
>     Thank you.
> David S.
David, there are many varieties of blood pressure medication that act
to lower blood pressure in different ways.  Some of them act by
relaxing smooth muscle and could probably contribute to incontinence.
Diuretics act by producing more urine, which could contribute to
incontinence.  There are lots of others that have different mechanisms
of action.  It's common practice for doctors to juggle BP medicine to
optimize effect and minimize side effects.  Don't ignore high blood
pressure, get treatment if you need it.  There is no question that
untreated high blood pressure can have dire consequences like heart
attacks and strokes.  Don't survive your PCa only to have a stroke!!
Good luck.  CPW
jimhoney - 09 May 2004 18:07 GMT
> David, there are many varieties of blood pressure medication that act
> to lower blood pressure in different ways.  Some of them act by
[quoted text clipped - 7 lines]
> attacks and strokes.  Don't survive your PCa only to have a stroke!!
> Good luck.  CPW

Dr. W,

And what is your opinion of non-prescription treatments for borderline
hypertension?  Things like garlic capsules or herbs.  I have always been
leery of them.

Jim
jk - 09 May 2004 22:39 GMT
> Dr. W,
>
[quoted text clipped - 3 lines]
>
> Jim

 Anything that works is a good thing Jim. It's easy enough to try herbal
stuff and see if it works for you. I found that simply losing weight,
(Atkins for years now),and exercise reduced my BP and took me of my meds for
4 years.

Signature

JK Sinrod
Sinrod Stained Glass Studios
www.sinrodstudios.com
Coney Island Memories
www.sinrodstudios.com/coneymemories

C. Paul Williams, MD - 10 May 2004 11:31 GMT
> And what is your opinion of non-prescription treatments for borderline
> hypertension?  Things like garlic capsules or herbs.  I have always been
> leery of them.

The problem with herbal remedies in general is that they are
incompletely studied.  Usually, the evidence supporting their efficacy
comes from anecdotal reports rather than controlled studies.
Also, manufacturing processes vary and aren't regulated, so you never
know for sure what you are getting or in what strength.
Some non prescription techniques that do work include exercise, weight
loss, and decreasing alcohol consumption....
CPW
C. Paul Williams, MD - 10 May 2004 22:10 GMT
> > And what is your opinion of non-prescription treatments for borderline
> > hypertension?  Things like garlic capsules or herbs.  I have always been
[quoted text clipped - 8 lines]
> loss, and decreasing alcohol consumption....
> CPW

....and smoking cessation and limiting salt intake....
CPW  :-)
Danny McCarty - 13 May 2004 00:59 GMT
>Subject: Re: Incontinence and high blood pressure.
>From: cpw@traverse.com  (C. Paul Williams, MD)
[quoted text clipped - 16 lines]
>....and smoking cessation and limiting salt intake....
>CPW  :-)

The infusion staff were verry worried about my high blood pressure, now -I- am
worried about my LOW blood pressure, 130/75.
C. Paul Williams, MD - 13 May 2004 10:47 GMT
> The infusion staff were verry worried about my high blood pressure, now -I- am
> worried about my LOW blood pressure, 130/75.

130/75 is perfect.  New guidelines recommend systolic (upper number)
of 130 or less and diastolic (lower number) of 80 or less.
Congratulations!
CPW
Leonard Evens - 13 May 2004 15:11 GMT
>>The infusion staff were verry worried about my high blood pressure, now -I- am
>>worried about my LOW blood pressure, 130/75.
[quoted text clipped - 3 lines]
> Congratulations!
> CPW

I find this somewhat amusing.  Normal blood pressure is usually defined
as 120/80 or lower.   I get worried a bit when my systolic blood
pressure consistently exceeds 130.   Systolic in the range 140-160 is
usually considered borderline high.  My blood pressure on occasion is
110 over 60, and I feel fine.  Once after taking Viagra with grapefruit
juice---not on purpose---the systolic pressure dropped below 100, but I
still felt fine.

I was under the impression that low blood pressure may in some cases be
a symptom of disease but is not in itself a problem in otherwise healthy
people.  Perhaps I am mistaken.

Actually blood pressure varies rather significantly throughout the day
and can depend on the circumstances.   It can depend on whether you are
lying down or sitting up and which arm is used.  Just moving around can
raise it.  It should be taken at the same time of day in standard
circumstances, and a single reading doesn't necessarily mean anything.
There is a condition called "white coat hypertension" where the patient
shows high blood pressure in the doctor's office but has normal blood
pressure at home.   I've suffered from that.  Also, I have to take
naproxen to control arthritis in my lower back, and it has a tendency to
raise my systolic pressure, which got into the borderline region at the
doctor's office.  I managed to get it back under control by losing about
25 lbs.
olfart - 13 May 2004 17:44 GMT
> >>The infusion staff were verry worried about my high blood pressure, now -I- am
> >>worried about my LOW blood pressure, 130/75.
[quoted text clipped - 28 lines]
> doctor's office.  I managed to get it back under control by losing about
> 25 lbs.

Just took mine and it's 107/70. I had good control and stayed around 130/70
until I went on Flowmax (2/day). Even with adjusting my B/P meds I run
anywhere from 140/85 down to the low 100's (even have had a few 98's). At
this point I feel lightheaded and know not to drive, etc. My Doc says the
low B/P while I'm on Flowmax won't do any harm except to watch out for temp
dizzyness, etc. Another month of Radiation and hopefully I can ditch the
flowmax and get B/P back to normal again.
Age - 69
8/12/02 - PSA 3.7
10/13/03 - PSA 4.69
11/11/03 - PSA 4.8
11/18/03 - Biopsy - 10 cores
one core-25% of core-Gleason 4+4=8
all other cores benign tissue
12/10/03 - Consult - Oncologist
12/16/03 - Consult - Radiation Oncologist
Treatment Plan - Northeast Ga Cancer Center
HT - started 12/17/03 - Eulixen & Lupron (2nd 4 mo Lupron-4/26)
2/10/04 - Started - Flowmax and Megastrol
Radiation - IMRT to begin 3/30/04 - 42 treatments
Leonard Evens - 13 May 2004 17:55 GMT
>>>>The infusion staff were verry worried about my high blood pressure,
>
[quoted text clipped - 39 lines]
> dizzyness, etc. Another month of Radiation and hopefully I can ditch the
> flowmax and get B/P back to normal again.

As we age, some of us find that the valves in the blood vessels in our
necks don't work too well.  That combined with low blood pressure can
lead to fainting when rising from a prone position.  Usually just being
careful when getting up will deal with it.   But I admit I have fainted
in such situations several times.

> Age - 69
> 8/12/02 - PSA 3.7
[quoted text clipped - 9 lines]
> 2/10/04 - Started - Flowmax and Megastrol
> Radiation - IMRT to begin 3/30/04 - 42 treatments
Larry - 13 May 2004 22:58 GMT
Pain meds can cause lowering of blood pressure. That was the reaction I had
when I had my Lymph Node Dissection and had APAP/Codeine "as needed for
pain". When I took one, my bp was very low but recovered quickly. With
Flomax I don't seem to have a problem with my blood pressure at all.
C. Paul Williams, MD - 13 May 2004 23:17 GMT
> > 130/75 is perfect.  New guidelines recommend systolic (upper number)
> > of 130 or less and diastolic (lower number) of 80 or less.
> > Congratulations!
> > CPW
>
> I find this somewhat amusing.

I'm delighted you are amused.
When treating a patient with known hypertension, physicians aim to
keep the systolic at 130 or lower and the diastolic at 80 or lower.  I
was responding to a gentlemen being treated for hypertension, not
espousing normal blood pressure levels for the general population.
For him to be concerned that his blood pressure of 130/75 was too low
was not reasonable, and I was attempting to reassure him....
sorry for the lack of accuracy.
CPW
Tom C - 14 May 2004 10:48 GMT
130/75 is great. Up to the time I saw a urologist for frequent urination in
Dec., the only BP checks I had were when I donated blood and it was always a
little high, 150/90 or so. On the morning of my biopsy it soared to 220/110,
the nurse told me not to think about the biopsy and to have pleasant
thoughts, yeah sure. Following that I did see a GP and have since gotten it
under control with some life style changes and meds, one of which (Cardura)
has a collateral effect on the prostate and has helped with urination
problems.

Similar to PCa, high BP doesn't exhibit any symptoms until it's too late,
the GP, quite frankly told me that if the BP continued the way it was, there
would be no need to worry about the cancer.

Tom

> > > 130/75 is perfect.  New guidelines recommend systolic (upper number)
> > > of 130 or less and diastolic (lower number) of 80 or less.
[quoted text clipped - 12 lines]
> sorry for the lack of accuracy.
> CPW
Leonard Evens - 14 May 2004 15:11 GMT
>>>130/75 is perfect.  New guidelines recommend systolic (upper number)
>>>of 130 or less and diastolic (lower number) of 80 or less.
[quoted text clipped - 11 lines]
> was not reasonable, and I was attempting to reassure him....
> sorry for the lack of accuracy.

Sorry.  My comments in no way were meant as a criticism of what you
said.  What I was amused about, as I hope my comments indicated, was
that someone should be concerned either way that his blood pressure was
130/75.   I should have responded to the original post, but for some
reason it was not available on my newsreader.   What you said was right
to the point.  If anyone else interpreted this as a criticism, I hope
this will clarify my intentions.

> CPW
C. Paul Williams, MD - 14 May 2004 23:17 GMT
> Sorry.  My comments in no way were meant as a criticism of what you
> said.  What I was amused about, as I hope my comments indicated, was
[quoted text clipped - 3 lines]
> to the point.  If anyone else interpreted this as a criticism, I hope
> this will clarify my intentions.

No problem...
Blood pressure control is a tricky medical condition and quite
important.
As you indicated, it varies in a diurnal fashion, varies depending on
who took it, etc.
The more you know about medicine, and, I suspect, advanced
mathematics, the more complicated it gets.
CPW
Danny McCarty - 14 May 2004 23:33 GMT
>Subject: Re: Incontinence and high blood pressure.
>From: cpw@traverse.com  (C. Paul Williams, MD)
[quoted text clipped - 9 lines]
>Congratulations!
>CPW

Thanks for the news!  Two months ago mine was 180/95, by the way.  Doc
prescribed a pill that had a diuretic in it... maybe that is why I leak like a
sieve now.
ButtercupsDad@dog.net - 10 May 2004 13:09 GMT
  Just a thank you to everyone that responded.  I will discuss this
in detail with my internist when I go for the next visit.  

David S.

>    In one of the recent posts the gentleman mentions experiencing some
>leakage due to being on high blood pressure medication.  Has anyone else
[quoted text clipped - 7 lines]
>    Thank you.
>David S.
 
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