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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2004

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Effexor for hot flashes?

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Sandy - 06 May 2004 01:09 GMT
After 5 months on Lupron with unrelenting hot flashes, my husband
finally broke down and decided to take something to help alleviate
them.  Much to my amazement, the oncologist prescribed low dose time
released Effexor which is an antidepressant.  I was expecting Megace
which I know has been traditionally used for hot flashes.  After
researching it on the internet, I do see that Effexor can reduce the
hot flashes by "60 percent" and is being utilized as such.  Just
curious - anyone else tried it and how successful was it in
alleviating the hot flashes?

Thanks,
Sandi
philski - 06 May 2004 04:22 GMT
> After 5 months on Lupron with unrelenting hot flashes, my husband
> finally broke down and decided to take something to help alleviate
[quoted text clipped - 8 lines]
> Thanks,
> Sandi
Just a note of warning. Effexor can cause a person to go into
anaphylactic shock. It did with my wife. I had to rush her to the
emergency clinic where she was VERY near having her airway completely
closed. They gave her epinepherine and admitted her for the night. She
did recover. We now have and Epi-Pen in case she shows signs in the
future. And I realize that most people my not have any adverse
reactions. I just want you to be aware things can happen...read up on
the drug and educate yourself....

Just my .02 worth...

Philski
DanR - 06 May 2004 23:32 GMT
I've tried the Effexor, I've had better results with Paxil.  Megace is
contraindicated for those with a history of PCa.
DanR
Lorelei - 07 May 2004 13:25 GMT
> I've tried the Effexor, I've had better results with Paxil.  Megace is
> contraindicated for those with a history of PCa.
> DanR

Didn't the Paxil knock out your libido? Curt quit taking it after a few days
because of that reason. I will bring up the Effexor at his next doctors
visit.

Signature

Lori
Devoted wife of Curtis, Stage 4 Prostate cancer at age 40
PSA 865    Dec 30,2003
         44     Feb  23,2004
         17.3  Mar 15,2004
         18.9 Apr 16, 2004
mets to bone and lymph
Lupron Q3months
Casodex 50 mg daily
http://community.webshots.com/user/lorismiller-date

DanR - 09 May 2004 03:14 GMT
What libido? I've been on HRT since Sept....hopefully it's reversible.
Alan Meyer - 14 May 2004 18:05 GMT
> What libido? I've been on HRT since Sept....hopefully it's reversible.

I got 4 months worth of Lupron.  The actual effects lasted
about 5-1/2 months.  But then everything came back.

   Alan
olfart - 14 May 2004 18:41 GMT
> > What libido? I've been on HRT since Sept....hopefully it's
> reversible.
[quoted text clipped - 3 lines]
>
>     Alan

My first 4 mo shot of Lupron started to wear off after about 3 1/2 mo and I
was making a little testosterone again. So when I got my second 4 mo shot at
the end of April I had to go through some of the "withdrawl" symptoms again
as it took effect. My URO says that the 4 mo life can vary + or - a several
weeks or so depending on  the individual. Since I will probably have to stay
on the damn stuff for at least another year or two, I'm going to have the 1
year implant done next time.
So much for Libido (:>)
Alan Meyer - 14 May 2004 23:45 GMT
> > > What libido? I've been on HRT since Sept....hopefully it's
> > reversible.
[quoted text clipped - 12 lines]
> year implant done next time.
> So much for Libido (:>)

I've always been surprised at how many drug dosages are
given without any special analysis of a person.

I weigh 148 pounds.  Another guy may weigh 248 pounds.
Yet we'd be given the same amount of Lupron and lots of
other drugs.

I imagine that for a lot of drugs that's right, but I always wonder
if the "average" dose only works properly on the "average"
person.
olfart - 15 May 2004 00:01 GMT
> I've always been surprised at how many drug dosages are
> given without any special analysis of a person.
[quoted text clipped - 6 lines]
> if the "average" dose only works properly on the "average"
> person.

I agree. I'm 6'4" and 210 lbs. So I can see where yours could last longer
than mine.
When my dog or cat get shots they are weighed first and dosed accordingly.
Maybe I'll see the Vet for my next Lupron fix (:>)
Danny McCarty - 16 May 2004 00:37 GMT
>Subject: Re: Effexor for hot flashes?
>From: "olfart" olfart65@excite.com
[quoted text clipped - 16 lines]
>When my dog or cat get shots they are weighed first and dosed accordingly.
>Maybe I'll see the Vet for my next Lupron fix (:>)

 There is only one item that is being affected by the Lupron- the pituitary
gland. Lupron tells the pituitary that there is plenty of testosterone in the
blood, and the pituitary in turn tells the testes to stop making it.
olfart - 16 May 2004 01:14 GMT
> >Subject: Re: Effexor for hot flashes?
> >From: "olfart" olfart65@excite.com
[quoted text clipped - 9 lines]
> gland. Lupron tells the pituitary that there is plenty of testosterone in the
> blood, and the pituitary in turn tells the testes to stop making it.

I understand this Danny, but the effect of the Lupron does not seem to be
constant over the 4 mo period for a 4 month shot. And it's effective period
seems to vary with the individual-my URO has confirmed this also. I was
starting to make testosterone after about 31/2 months. He would have given
me my next shot then except that Medicare would not have paid for it. It may
not be body size or weight that determines the effective length of the
shot - could be other factors.
Danny McCarty - 17 May 2004 04:51 GMT
>Subject: Re: Effexor for hot flashes?
>From: "olfart" olfart65@excite.com
[quoted text clipped - 25 lines]
>not be body size or weight that determines the effective length of the
>shot - could be other factors.
  Yes, that was the point of my post.  The implant releases Lupron at some
relatively constant rate and that creates a blood level that the pituitary
reads.  There isn't much else that absorbs the Lupron, although my breasts were
a little prominent for a while... ;-}
Gary Nichols - 07 May 2004 13:38 GMT
> After 5 months on Lupron with unrelenting hot flashes, my husband
> finally broke down and decided to take something to help alleviate
[quoted text clipped - 8 lines]
> Thanks,
> Sandi

I've been taking Effexor for about two years (as an anti-depressent).  Other
that the fact that . very occasionally, my face and ears feell flushed
I don't really know what a hot flash is.

gn
Lillian - 07 May 2004 19:45 GMT
I took it for awhile for hot flashes.  It didn't really help, and I
did not like the way I felt on it.  My sister has been taking it for
awhile for depression, and it works for that, but she still has hot
flashes.  My doctor said that he felt that it helped about 40% of the
women he gave it to for hot flashes.
Larry - 08 May 2004 13:39 GMT
Your comment "very occasionally, my face and ears feel flushed"  was
interesting. I feel the same way quite often and don't know what to make of
it. I would think that a hot flash has more to it than that. I'm not taking
anything for that yet.

> I've been taking Effexor for about two years (as an anti-depressent).  Other
> that the fact that . very occasionally, my face and ears feell flushed
> I don't really know what a hot flash is.
>
> gn
Gary Nichols - 08 May 2004 15:08 GMT
> Your comment "very occasionally, my face and ears feel flushed"  was
> interesting. I feel the same way quite often and don't know what to make of
> it. I would think that a hot flash has more to it than that. I'm not taking
> anything for that yet.

I hate to bring this up but are you a diabetic.  My doctor blames my
'flushed' feeling on my diabetes.  But then he blames just about every bad
feeling-nausea, sweating, etc-on diabetes.  So I'm sure there are many
reasons for the 'flushed' feeling.  Mention it to your doctor.  Mine says
that it is nothing to worry about.  When I do get flushed ut is usually in
the eveniing.

gn

> > I've been taking Effexor for about two years (as an anti-depressent).
> Other
> > that the fact that . very occasionally, my face and ears feell flushed
> > I don't really know what a hot flash is.
> >
> > gn
Larry - 08 May 2004 15:24 GMT
Thanks for the tip Gary. Nope, I'm not diabetic. But I will take your advice
and mention it during my weekly visit with my oncologist (during the rad
treatments). Since it's not significant, I didn't consider it worth
mentioning. Too many other *important* things such as impotence to concern
myself with <g>. I can feel flushed anytime. Like now for instance.

> > Your comment "very occasionally, my face and ears feel flushed"  was
> > interesting. I feel the same way quite often and don't know what to make
[quoted text clipped - 18 lines]
> > >
> > > gn
 
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