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Medical Forum / Diseases and Disorders / Prostate Cancer / May 2004

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Clinical Trials

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Carolyn Preston - 30 Apr 2004 22:54 GMT
Just got home from the Royal Marsden Hospital (London) after
commencing stage I clinical trial of taxotere combined with omnitarg.

Had the IV infusion of taxotere on day one (Wednesday) and the
omnitarg on day two.  Next cycle (in three weeks) both will be on the
same day.

Will post results as available.

--
John Preston

GSX1400
Some Big Kites
and a Land board
Steve Kramer - 01 May 2004 02:16 GMT
Did they do a baseline, John.  Or are they going off your February PSA?

Signature

Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000
PSA  .1  .1  .1  .3  .4  .8
EBRT 05-07/2002 @ 47
PSA  .3 .2  .2  .2 .3
Erection 05/12/2003 @ 48
HTbegins 07/21/2003 @ 48
PSA  .1
Lupron 7/03, 8/03, 12/03

> Just got home from the Royal Marsden Hospital (London) after
> commencing stage I clinical trial of taxotere combined with omnitarg.
[quoted text clipped - 11 lines]
> Some Big Kites
> and a Land board
John Loomis - 01 May 2004 02:51 GMT
Hello John,
I hope you are doing fine.  I realize you may be undergoing clinical trials
and such. I do have my best for you!
Big Kites.......Now you have my attention.
I build kites and large ones. Small ones too,
The last kite was so big, I could not keep it from flying out of my truck as
I drove to the kite fare.
When I got there it was not enough wind to blow the grass sideways.....
I sat there with my "Big Kite" and no wind.....did I feel like a dummy!
Anyway, I saved my kites, and will try them for the 3rd  time, find a windy
day, and let them sail!
Good wishes for you and anybody that fly's kites is a lover of life.
I hope you get the respect, and the medicine needed to make your life the
best.
RP 1999 going on 4.5 years.  surviving.....I am in a similiar boat!
John Loomis
> Just got home from the Royal Marsden Hospital (London) after
> commencing stage I clinical trial of taxotere combined with omnitarg.
[quoted text clipped - 11 lines]
> Some Big Kites
> and a Land board
Carolyn Preston - 01 May 2004 11:13 GMT
Further info:

PSA on dx (Apr 2003 at age 48) - 640 with widespread bone mets.

Tx - 3 weeks Casodex, then Zoladex.  PSA down to 14.4.

One injection of Strontium & one shot of radiotherapy to right
shoulder.

Monthly Zometa.

Recent PSAs:

10 Dec 2003 - 18.8
04 Feb 2004 - 25.3
17 Mar 2004 - 32.2
26 Mar 2004 - 46.0
21 Apr 2004 - 34.9 (blip?)

New bone scan looks the same as last year :-)
Lower abdomen CT scan clear.

Muga (heart) scan & 12 lead ECG tracings all OK

No side effects as yet.

--
John Preston
Steve Kramer - 02 May 2004 01:40 GMT
Let's hope the 46 was a blip and the trial is the el kabong.

Signature

Prostate Cancer Survivor (so far), not a doctor
PSA 16 10/17/2000 @ 46
Biopsy 11/01/2000 G7 (3+4), T2c
RRP 12/15/2000
PSA  .1  .1  .1  .3  .4  .8
EBRT 05-07/2002 @ 47
PSA  .3 .2  .2  .2 .3
Erection 05/12/2003 @ 48
HTbegins 07/21/2003 @ 48
PSA  .1, .1
Lupron 7/03, 8/03, 12/03, 4/04

> Further info:
>
[quoted text clipped - 24 lines]
> --
> John Preston
Lorelei - 03 May 2004 16:03 GMT
> Further info:
>
[quoted text clipped - 24 lines]
> --
> John Preston

hang in there John and keep us posted.
Curt had a huge drop and then a little hiccup up. we will know more in 2
weeks. (next Zometa and PSA)

Signature

Lori
Devoted wife of Curtis, Stage 4 Prostate cancer at age 40
PSA 865    Dec 30,2003
         44     Feb  23,2004
         17.3  Mar 15,2004
         18.9  Apr   16,2004
mets to bone and lymph
Lupron Q3months
Casodex 50 mg daily
http://community.webshots.com/user/lorismiller-date

Alan Meyer - 02 May 2004 19:51 GMT
> Just got home from the Royal Marsden Hospital (London) after
> commencing stage I clinical trial of taxotere combined with omnitarg.
[quoted text clipped - 4 lines]
>
> Will post results as available.

That sounds like a very advanced type of treatment.

Good luck with it and, on behalf of present and future
cancer patients, thank you for helping to find remedies
of interest to us all.

   Alan
Carolyn Preston - 02 May 2004 20:29 GMT
Thankyou,  John is the first person to ever try Taxotere
(chemotherapy) and Omnitarg (antibody) together. If he is ok they will
enrol two more patients in two weeks time. We look at the fact that
John will shortly be in serious trouble with this cancer if we don't
do anything as conventional treatment has failed and he is now hormone
refractive.
We have no intentions of giving in yet and if this trial turns out to
be to bad and not worth the benefits we will simply stop it. My John
is a fit lad and loving family man, kind and sweet, l love him to bits
and he has lots to stick around for.I will get him to put a link up
with photos so you can see us and put faces to names.
Take care
love
Carolyn
uk

"> That sounds like a very advanced type of treatment.

> Good luck with it and, on behalf of present and future
> cancer patients, thank you for helping to find remedies
> of interest to us all.
>
>     Alan
Beverley - 03 May 2004 01:17 GMT
Clinical trials usually seem to bring about good results. Here's to hope
that John does well with this. I'll cross my fingers and toes for the two if
you.
Bev

> Thankyou,  John is the first person to ever try Taxotere
> (chemotherapy) and Omnitarg (antibody) together. If he is ok they will
[quoted text clipped - 19 lines]
> >
> >     Alan
Lorelei - 03 May 2004 16:09 GMT
> Thankyou,  John is the first person to ever try Taxotere
> (chemotherapy) and Omnitarg (antibody) together. If he is ok they will
[quoted text clipped - 11 lines]
> Carolyn
> uk

We think and speak about you and John often here in the Miller home. We send
our prayers out to you both.
Lori Miller
Danny McCarty - 02 May 2004 23:36 GMT
>Subject: Re: Clinical Trials
>From: "Alan Meyer" ameyer2@yahoo.com
[quoted text clipped - 11 lines]
>>
>> Will post results as available.

I had taxotere IV infusion with seven days of ketoconozole tablets, alternating
weekly with adriamycin IV and seven days of estramustin tablets, for three
sessions of eight weeks each.  Seems to have worked for me.  My maximum PSA so
far was 35.
Danny McCarty - 02 May 2004 22:54 GMT
>Subject: Clinical Trials
>From: "Carolyn Preston" carolyn.preston@ntlworld.com
[quoted text clipped - 16 lines]
>Some Big Kites
>and a Land board

Hmmm, the John Preston of Preston's Market in Rawsonville, where I worked
evenings 45 years ago, had a son named John...  ???
 
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