I pulled my rad rpt and it does not state anything about a lymp it does
say
R seminal vesicle has slightly heterogeneous attenuation but normal in
size  L s.v. appears normal.  Guess today got to me a bit more than I
realized  j.d.

John,

Initially, other than a sore arm, you'll probably see hardly any
effect.  It takes a few weeks for the Lupron to kick in.  After that
you may begin to get hot flashes, very gradual loss of bone and/or
muscle tissue, and lower and lower libido.  The full effects may
take 6 weeks or so before you really see them.

The PSA will go down.  It may take two months or more
to hit bottom.

You can counteract a lot of the negative effects.  Exercise will
help prevent muscle loss.  Calcium + exercise will help prevent
bone loss.  Hot flashes are, well, hot flashes.  Some people
are very upset by them, some don't care.  Your wife can
probably advise you on how to deal with them (it may give
you some appreciation of what the ladies go through.)

The decline in libido is less straightforward to combat.  A
doctor told me, "You won't be able to get an erection, and
you won't care."

I found that I was still able to have sex with Lupron, but it
required more stimulation and more effort.  Believing that the
most important sexual organ is between the ears, I found that
that one still worked and was able to command the others
at least to the extent of doing something.

Best of luck with it.

   Alan

Well, John, it looks like you got some replies, but none that help.  And, I
apologize for getting to it 4 days later, but I've been extremely busy.

You first need to know, if you don't already, that you have advanced
prostate cancer and there is no cure for advanced prostate cancer.  There
are some things in the works and we are mostly confident that if we can live
5-10 years, we will see a cure.  So, it is living 5-10 years on which you
should now focus.

The treatments you are getting should take your PSA from 16.7 down to single
digits in very short order.  With cancer in your bone and lymph nodes, a PSA
at 0.1 or less would be asking a lot, but it is possible.  Since you started
at 16.7, who knows?  I started at 16 and my last PSA, with Lupron, was 0.05.
There are a dozen people over the last three years who were diagnosed with
advanced prostate cancer.  Only three had PSA as low as yours and all three
are still alive, so far as I know.

So, I'd say you may expect a few years of a good life and at some point you
will need to do something else.  Hopefully, that something else will be a
cure.  But, no one can tell you when that will be.