Medical Forum / Diseases and Disorders / Prostate Cancer / February 2004
Nutrition and PCa
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Steve Kramer - 22 Feb 2004 23:54 GMT Recently, someone asked about nutrition and PCa and dammit if I didn't get a newsletter from my Prostate Cancer Networking Group about it. There are 9 bullets:
1. Good nutrition reduces the incidence of prostate cancer. "No doubt about that." (Oh, well. Too late for us.)
2. Good nutrition reduces PCa progression. "Thus far, lycopene is the only example of a substance that can lower PSA and reduce PCa mortality."
3. Carbs are bad for some mice with PCa. "Two groups of mice were fed a diet with the same calories, but with different fat and carbohydrate percentages." "At 28 weeks, 5% of the mice fed 45% fat had died of PCa as compared with 31.8% of mice fed 10% fat."
4. Carbs are good for men with PCa. "After one year, "mean PS levels decreased by 3% in the experimental group and increased 7% in the control group." (So, are you a man or a mouse?).
5. Lycopene and tomato paste reduce PSA. "PSA levels decreased by 18% in the intervention group, whereas they increased by 14% in the control group."
6. Small dosage of Lycopene reduces prostate cancer mortality. "After 2 years 11 patients in the orchidectomy group and 21 in the orchidectomy + lycopene group had a PSA <0.05. ... 12 in the O-group and 7 in the O+L group died." (BTW, they were taking only 4mg of Lycopene a day.)
7. Diet restriction makes rate live longer. "starved rats die later of PCa than well-fed rats." (I trust rats over mice any day -- Sorry Martin.)
8. Tomatoes are more effective than Lycopene? "The percentages of rats dying with PCa were 80%, 72%, and 62% for the control, lycopene, and tomato powder groups, respectively.
9. Eat tomatoes! "The greatest protection was associated with an intake of 10 or more servings of tomato products each week." "The simplest approach is to have an 8-ounce glass of tomato juice or V8 juice every morning." (During this reading, I was wondering just how I could get that much tomato in me. Then it dawns on me. I could have had a V8!)
 Signature Prostate Cancer Survivor (so far), not a doctor PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 PSA .1 .1 .1 .3 .4 .8 EBRT 05-07/2002 @ 47 PSA .3 .2 .2 .2 .3 Erection 05/12/2003 @ 48 HTbegins 07/21/2003 @ 48 PSA .1 Lupron 7/03, 8/03, 12/03
John Loomis - 23 Feb 2004 03:05 GMT Hey, I have grown the best tomatoes, for years, and well before dxs'ng. RP @ 49 Yeah, I ate tomatoes, and even before they came into this news group as cancer aids......... I still eat tomatoes, and love everyone, and her sister...... Anyway, trying to be a bit silly. Yes, I have eaten my share of tomatoes, grown them, and eat garlic, and onions, and now mostly buy organic food. Cost 2 times as much as regular So far I have gotten prostate cancer, when 49. Can tomatoes help? I wonder
> Recently, someone asked about nutrition and PCa and dammit if I didn't get a > newsletter from my Prostate Cancer Networking Group about it. There are 9 [quoted text clipped - 35 lines] > (During this reading, I was wondering just how I could get that much tomato > in me. Then it dawns on me. I could have had a V8!) Steve Kramer - 23 Feb 2004 10:58 GMT You ate tomatos a lot more than me and I got cancer at 46. Proof!
 Signature Prostate Cancer Survivor (so far), not a doctor PSA 16 10/17/2000 @ 46 Biopsy 11/01/2000 G7 (3+4), T2c RRP 12/15/2000 PSA .1 .1 .1 .3 .4 .8 EBRT 05-07/2002 @ 47 PSA .3 .2 .2 .2 .3 Erection 05/12/2003 @ 48 HTbegins 07/21/2003 @ 48 PSA .1 Lupron 7/03, 8/03, 12/03
> Hey, I have grown the best tomatoes, for years, and well before dxs'ng. RP > @ 49 [quoted text clipped - 53 lines] > tomato > > in me. Then it dawns on me. I could have had a V8!) Larry Wheat - 24 Feb 2004 01:37 GMT > Hey, I have grown the best tomatoes, for years, and well before dxs'ng. RP > @ 49 [quoted text clipped - 6 lines] > So far I have gotten prostate cancer, when 49. > Can tomatoes help? I wonder The stuff I've read says that cooked tomato sauces deliver more lycopene than raw tomatoes.
If you ate all cooked tomatoes, you plainly didn't eat enough, right?
Larry (also silly)
Dave P - 23 Feb 2004 15:31 GMT Thanks for the post Steve.
Dave P.
> Recently, someone asked about nutrition and PCa and dammit if I didn't get a > newsletter from my Prostate Cancer Networking Group about it. There are 9 [quoted text clipped - 35 lines] > (During this reading, I was wondering just how I could get that much tomato > in me. Then it dawns on me. I could have had a V8!) c palmer - 23 Feb 2004 16:58 GMT hi john - last year, someone wrote in and made a comment about how tomatoes help prevent prostate cancer and i wrote a response about like you did.
i love tomatoes, had eaten them all my life and still eat at least one to two lbs a week now. i ended up with pca at age 56 and ask the poster did it help me.
he wrote back and said - well, maybe you would have gotten pca at age 53 instead.
~ curtis
knowledge is power - growing old is mandatory - growing wise is optional
DanR - 28 Feb 2004 20:09 GMT it is supposed to be cooked tomatoes...and what's the hard part about eating vegetables....
Jack - 24 Feb 2004 19:45 GMT A couple of weeks ago I heard or read about a recent study with Harvard involvement. I think it concluded that Lycopene supplements were less effective than cooked tomatoes in a variety of forms including: -- tomatoe sauces -- katchup (beware the high sodium) Personally, I open a can or tomato paste and choke down a healthy tablespoonfull a day or spread it on sandwiches, beans, etc. Not too bad actually. Dr. Charles Myers advocates this approach which is cheap and easy. I recall some additional results that indicated that the tomatoes needed to be cooked in oil (preferably a little olive oil) to get the most beneficial results. (I found a cy of what I had read. See below.) Jack Davis Sarasota, Fl ========================== Wednesday, March 06, 2002
WASHINGTON Men who consume tomato products two or more times a week can significantly reduce their chances of contracting prostate cancer, a study found.
Eating cooked tomatoes was particularly beneficial, according to the study, which showed that regularly eating tomato sauce, ketchup and other tomato-based foods lowered the prostate cancer risk by as much as 36 percent.
Dr. Edward Giovannucci of Brigham and Women's Hospital and the Harvard School of Public Health, the first author of the study, said it supported earlier research involving foods such as tomatoes that were high in lycopene, a powerful antioxidant.
"These most recent findings add support to the notion that a diet rich in tomatoes and lycopene-containing foods, as well as other fruits and vegetables, may reduce the risk of prostate cancer," Giovannucci said.
A report on the study appears Wednesday in the Journal of the National Cancer Institute.
Researchers analyzed the food choices and prostate cancer histories of more than 47,000 men and found that those who ate at least two meals a week containing tomato products lowered their risk of prostate cancer by 24 percent to 36 percent.
Giovannucci said that lycopene is thought to protect against cancer by absorbing oxygen free-radicals, which are chemicals created during metabolism that can damage the genetic structure of cells.
The finding is based on data from the Health Professional Follow-Up Study, a project that followed the health history and dietary habits of 47,000 men, aged 40 to 75, from 1986 to 1998. During that period, 2,481 of the men developed prostate cancer.
Dietary questionnaires in the study included such food items as tomatoes, tomato sauce, tomato juice, pizza, watermelon and pink grapefruit, along with salsa, ketchup and other tomato-based condiments.
When the data was adjusted for the effects of other life style factors, the researchers found that tomatoes, especially if they had been cooked, were beneficial against prostate cancer.
"Spaghetti sauce was the most popular" and also seemed to give the most protection, said Giovannucci. He said that cooking raw tomatoes, as is done to make spaghetti sauce, may break down cell walls of the fruit and allow the body to absorb more lycopene.
Jo Ann Carson, a clinical nutritionist at the University of Texas, Southwest Medical Center in Dallas, said the study "is an example that what we eat can affect our risk of cancer."
The study also supports the idea that foods rich in antioxidants, rather than vitamin pills, provide the most cancer protection, she said.
"Eating the whole foods seems to give a beneficial combination that would be lacking in supplements," Carson said.
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Danny McCarty - 25 Feb 2004 03:29 GMT >Subject: Re: Nutrition and PCa >From: jstuartd1@aol.com (Jack) >Date: 2/24/2004 1:45 PM Central Standard Time >Message-id: <85cb59f7.0402241145.be33efb@posting.google.com> The conclusions are all STATISTICS! Eating tomatoes improves your ODDS, but provides no GUARANTEES!
>A couple of weeks ago I heard or read about a recent study with >Harvard involvement. I think it concluded that Lycopene supplements [quoted text clipped - 77 lines] > >=======
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