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Medical Forum / Diseases and Disorders / Cancer / March 2008

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Prevents Tumor Metastasis

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ironjustice - 10 Mar 2008 04:57 GMT
If beta-Sitosterol is found IN soybeans then wouldn't this mixture
below BE .. soybean lecithin .. ?

Imanaka H, Koide H, Shimizu K, Asai T, Kinouchi Shimizu N, Ishikado A,
Makino T, Oku N
Chemoprevention of Tumor Metastasis by Liposomal beta-Sitosterol
Intake. [Journal Article]
Biol Pharm Bull 2008 Mar; 31(3):400-4.

To investigate chemopreventive effect of liposomal beta-sitosterol on
tumor metastasis, we prepared liposomal beta-sitosterol composed of
egg yolk phosphatidylcholine for oral delivery. Although orally
administered beta-sitosterol (4 mumol as beta-sitosterol/mouse) was
not absorbed into plasma, the amount of immune response cytokines such
as IL-12 and IL-18 was increased in the small intestine after the
liposome intake.
Moreover, after daily oral administration of the liposome for 7 d,
natural killer (NK) cell activity in the mice was increased,
suggesting that the immune surveillance activity of mice was enhanced
by the liposomal beta-sitosterol intake.
Thus, we examined metastatic potential of B16BL6 melanoma cells, which
were intravenously injected into mice after sequential administration
of liposomal beta-sitosterol for 7 d. The number of metastatic
colonies in the lungs was significantly less than that of control
group two weeks after the injections of the cells.
These results suggest that daily liposomal beta-sitosterol intake
prevents tumor metastasis may be due to enhancement of gut immune
surveillance systems.

Biological & pharmaceutical bulletin [Biol Pharm Bull]
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Homenet - 11 Mar 2008 14:15 GMT
> If beta-Sitosterol is found IN soybeans then wouldn't this mixture
> below BE .. soybean lecithin .. ?
[quoted text clipped - 36 lines]
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk

An excellent report, thanks.

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