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Medical Forum / Diseases and Disorders / Cancer / November 2007

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Researchers have bred a 'Supermouse' that is invulnerable to cancer.

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Joe - 28 Nov 2007 22:03 GMT
Story via http://Muvy.org
betsyb - 28 Nov 2007 22:17 GMT
> Story via http://Muvy.org

Maybe if in my next life I will return as a mouse and then this will
really mean something.
Tim Jackson - 29 Nov 2007 09:00 GMT
>> Story via http://Muvy.org
>
> Maybe if in my next life I will return as a mouse and then this will
> really mean something.

I can't see the original post, Supernews seems to have censored it for
inscrutable reasons of their own, but the link is to a story on the BBC
that University of Kentucky researchers have bred a line of mice with an
added active gene for the protein "prostate apoptosis response-4"
(Par-4), which appear not to get cancers.
( news.uky.edu/news/display_article.php?artid=2937 )

In previous lab studies they have shown that Par-4 which in involved in
the cell-death or apoptosis mechanism, causes cells which become
cancerous to die more readily.  This latest development shows that mice
can live apparently healthy normal lives with this gene, that it is not
killing off normal cells.

However earlier research by the same team implicated the same gene in
the development of Alzheimer's disease, so it is clear that there is
much work needed before this comes near to producing a useful treatment
for human cancer.
( www.sciencedaily.com/releases/1998/08/980814064931.htm )

Tim Jackson
J - 29 Nov 2007 09:47 GMT
> > "Joe" <useful_infos@yahoo.com> wrote in message
> <snip the web page>
[quoted text clipped - 11 lines]
> the cell-death or apoptosis mechanism, causes cells which become
> cancerous to die more readily.

Well, thanks for that, Tim.
alt.support.cancer's not especially interested in mouse studies because there's
thousand's and thousands; many of which go nowhere and the ones that do - from
bench to bedside take 10 or more years.
And many here don't have that time.
I think that was Betsy's point.

It was crossposted by a man who posts the same page, from time to time,
probably a make money page.
His page has got advertisements on it and if I'm understanding this correctly
http://www.cancerlynx.com/hits.html
he probably has a log file that says how many times his pages or graphics were
viewed so he can report it to his advertisers.

J [one newsgroup trimmed]
Tim Jackson - 29 Nov 2007 11:16 GMT
>>> "Joe" <useful_infos@yahoo.com> wrote in message
>> <snip the web page>
[quoted text clipped - 10 lines]
> And many here don't have that time.
> I think that was Betsy's point.

I think it was my point too.

> It was crossposted by a man who posts the same page, from time to time,
> probably a make money page.

That perhaps is why it was censored.  I didn't mean to raise the Usenet
censorship issue here, it's a bit OT, but I think this one is a grey
area at least.  After all J, he is not the only person to repost web
articles to Usenet groups of appropriate topic. If he hosts his news on
a website that is financed by a few inconspicuous ads down the side, I
can't really get upset about that being commercial advertising on
Usenet.  He's doing nothing fundamentally different from Medscape or any
commercial news service.  Should I get banned because I sometimes cite
Medscape articles?  If the poster also owns the news site, it may be
incest or narcissism but I doubt you could make a case for abuse on that
basis alone.

Posting a summary and link to the original article does defeat his
profit mechanism.  Although I fumbled it, the link should of course have
had "http://" on the front.

Tim
Tim Jackson - 29 Nov 2007 12:01 GMT
>>>> "Joe" <useful_infos@yahoo.com> wrote in message
>>> <snip the web page>
[quoted text clipped - 3 lines]
>>> I can't see the original post, Supernews seems to have censored it for
>>> inscrutable reasons of their own,

To clarify, I have in the last few minutes received an explanation from
Supernews as to why posts such as this are being blocked.  It appears
that there is a technical incompatibility between their server and
Google's which results in all crossposted messages posted through Google
Groups not getting crossposted but only appearing on the first named
newsgroup on the Supernews server.

At present they seems to be in dispute as to who's interpretation of the
interface specification is correct.

Tim
 
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