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Medical Forum / Diseases and Disorders / Cancer / October 2007Steph: Plasmacytoma case
The mother of a friend of mine (~80 years old) was diagnosed with a plasmacytoma in her chest between the ribs a litle less than a year ago. A bone scan at that time was negative. The oncologist performed 23 sessions of radiation (sorry, don't know dose) and the latest CT scan shows no reduction in the size of the tumor. There is concern of this tumor becoming a myeloma, but blood tests for markers are still OK. My friend said that the oncologist was "visibly perplexed" that the tumor didn't respond to the treaments and has now proposed chemotherapy. Comments? What are the statistics of these becoming a myeloma and is it really uncommon for a tumor such as this to not respond to radiation? TIA, - John Have you read the NCI Cancer Topics pages on the various kinds of plasmacytoma? Here is a page to get you started. Note the menu on the left and also the 2 versions, for patients and health professionals. http://www.nci.nih.gov/cancertopics/pdq/treatment/myeloma/HealthProfessional/page7 Una > The mother of a friend of mine (~80 years old) was diagnosed with a plasmacytoma in her > chest between the ribs a litle less than a year ago. A bone scan at that [quoted text clipped - 10 lines] > > - John Hi John, Where's the patient? US? Canada? Or? Steph recently said that BC's protocol is 4500 cGy in 20 sessions. archived < http://groups.google.com/group/alt.support.cancer/browse_thread/thread/289bbb515 da10435/94f7a1f9f48c5725?lnk=st&q=#94f7a1f9f48c5725 I don't know if her age or the location would make a difference so watch for his reply, please. J > > The mother of a friend of mine (~80 years old) was diagnosed with a plasmacytoma in her > > chest between the ribs a litle less than a year ago. A bone scan at that [quoted text clipped - 10 lines] > > > > - John > Hi John, > Where's the patient? US? Canada? Or? [quoted text clipped - 4 lines] > I don't know if her age or the location would make a difference so watch for his reply, > please. She's in the US. (California) >> > The mother of a friend of mine (~80 years old) was diagnosed with a >> > plasmacytoma in her [quoted text clipped - 29 lines] > > She's in the US. (California) Watch out for Alex. She'll jump in with some bad advice any second............ >>> > The mother of a friend of mine (~80 years old) was diagnosed with a >>> > plasmacytoma in her [quoted text clipped - 32 lines] > Watch out for Alex. She'll jump in with some bad advice any > second............ Ok, only you and J give good advice. >>>> > The mother of a friend of mine (~80 years old) was diagnosed with a >>>> > plasmacytoma in her [quoted text clipped - 34 lines] > > Ok, only you and J give good advice. That's not true. I just don't give bad, ill-informed advice. > The mother of a friend of mine (~80 years old) was diagnosed with a > plasmacytoma in her [quoted text clipped - 15 lines] > > - John Plasmacytomas sometimes don't disappear on CT, but if you biopsy them, there are often no viable plasmacytoma cells left, so I usually treat the patient, not the CT. Having said that, about 50% of patients with plasmacytoma will develop myeloma eventually. The diagnosis is not based on whether the plasmacytoma disappears or not - it's the same disease as myeloma, only localised. The diagnosis of MM requires multiple lytic lesions in bones, or a positive bone marrow. If a patient of 80 has no symptoms, there is absolutely no indication to treat MM, at least not urgently. |
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