Can you swallow the "giant" tablet? I am wincing just thinking about it.

Still keeping you in my thoughts and prayers and hoping you make a
speedy recovery from the radiation.

Hugs from Texas,
Janet

Nystatin is good against fungal infections, but may lose some of its
efficacy over time. Another compound, which IMHO nicely could assist
Nystatin in the fight against oral and throat fungal infections is bee
product Propolis. I've used propolis for years and am quite happy with
the results. Propolis has a wide spectrum of antimicrobial effects, it
works also against bacteria and viruses. It has anti-cancer effects,
too. And it has especially nice feature for H&N cancer patients, who
are going or have gone through radiation therapy: it has a mild local
anaesthetic action. It mildly numbs the throat and mouth, when used
superficially for example by gurgling with propolis extract-water
mixture or by sucking a propolis lozenge. Numbing effect is so mild,
that it does not disturb swallowing function.

Propolis is also available as capsules or tablets to be swallowed.
These have systemic immunostimulating and immunomodulating effects
helping to move T-helper cell Th1/Th2-balance from excessive
Th2-dominance towards Th1-response.

Propolis can cause allergic reactions on people who are prone to them.
Therefore it's best to start with extremely small dose to see, if any
allergic reaction develops, and only slowly increase the dose, until
the possibility of an allergic reaction can be ruled out with a great
enough probability.

Below some propolis related links:

Propolis - Wikipedia, the free encyclopedia
<http://en.wikipedia.org/wiki/Propolis>

   "Propolis is a wax-like resinous substance collected by honey
   bees from tree buds or other botanical sources and used as
   cement and to seal cracks or open spaces in the hive. Its
   color varies from green to brown and reddish, depending of
   its botanical source. Honey bees will use propolis to attempt
   to seal any gap inside the hive that is smaller than 3/16" or
   1/4" (5 mm or 6 mm) while they leave themselves a bee space
   of approximately 9.5 mm, or 3/8", larger spaces being filled
   with wax comb.
   
   [...]
   
   Depending upon its precise composition it may show powerful
   local antibiotic and antifungal properties. Also it is
   generally efficient in treating skin burns. Claims have been
   made for its use in treating allergy; it may stimulate the
   immune system, but some warn that it should not be taken if
   the user is likely to have severe allergic reaction to bees,
   as small fragments of bee exoskeleton may be present.
   
   Old beekeepers recommend a piece of propolis kept in the
   mouth as a remedy for a sore throat."

A Comprehensive Guide on Bee's Propolis
<http://www.beepropolis.info/>

MedlinePlus Herbs and Supplements: Propolis
<http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient-propolis.html>

Propolis - InteliHealth
<http://www.intelihealth.com/IH/ihtIH/WSIHW000/8513/31402/346981.html?d=dmtContent>

Propolis
<http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/pro_0294.shtml>

   "RESEARCH SUMMARY
   
   have shown anti-bacterial, anti-viral and anti-fungal
   effects. It shows activity in culture against a broad
   spectrum of pathogens, including influenza and herpes
   viruses, as well as HIV and various fungal and bacterial
   organisms.

   In a study of school children, an aqueous propolis extract
   was judged effective in reducing the incidence and intensity
   of acute and chronic rhinopharyngitis. In another study
   involving 10 volunteers, it exerted activity against oral
   bacteria. A Cuban study concluded that propolis is more
   effective than tinidazole against giardia.

   Propolis has a high concentration of caffeic acid esters that
   some believe may give it some antitumor properties. In two
   studies, extracts of propolis fed to rats have inhibited
   azoxymethane-induced colonic tumors.

   In vitro studies have shown propolis-related anti-
   inflammatory effects. Various extracts of propolis have also
   shown anti-inflammatory activity in animal models,
   particularly against adjuvant-induced arthritis.

   More research is needed to further explore these preliminary
   findings."

Propolis- The Most Natural Antibiotic
<http://www.elements.nb.ca/theme/ethnobotany/propolis/propolis.htm>

Canadian Honey Council - Propolis
<http://www.honeycouncil.ca/users/folder.asp?FolderID=4667>

Medical Journals Document Value
of Bee Propolis, Honey and Royal Jelly
<http://www.nutritionreporter.com/bee_stuff.html>

Propolis - Herbs & Supplements - Drug Library - DrugDigest
<http://www.drugdigest.org/DD/PrintablePages/herbMonograph/0,11475,4068,00.html>

Propolis heals herpes lesions faster than acyclovir
<http://www.herbs.org/current/propolis.htm>

Scientific propolis references from Medline:

1:  Samet N, Laurent C, Susarla SM, Samet-Rubinsteen N.
The effect of bee propolis on recurrent aphthous stomatitis: a pilot
study.
Clin Oral Investig. 2007 Jun;11(2):143-7. Epub 2007 Feb 7.
PMID: 17285269 [PubMed - in process]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=17285269>

2:  Fernandes FF, Dias AL, Ramos CL, Ikegaki M, Siqueira AM, Franco
MC.
The "in vitro" antifungal activity evaluation of propolis G12 ethanol
extract on Cryptococcus neoformans.
Rev Inst Med Trop Sao Paulo. 2007 Apr;49(2):93-95.
PMID: 17505666 [PubMed - as supplied by publisher]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=17505666>

3:  Koru O, Toksoy F, Acikel CH, Tunca YM, Baysallar M, Uskudar Guclu
A, Akca E, Ozkok Tuylu A, Sorkun K, Tanyuksel M, Salih B.
In vitro antimicrobial activity of propolis samples from different
geographical origins against certain oral pathogens.
Anaerobe. 2007 Mar 7; [Epub ahead of print]
PMID: 17475517 [PubMed - as supplied by publisher]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=17475517>

4:  Ahn MR, Kunimasa K, Ohta T, Kumazawa S, Kamihira M, Kaji K, Uto Y,
Hori H, Nagasawa H, Nakayama T.
Suppression of tumor-induced angiogenesis by Brazilian propolis:
Major component artepillin C inhibits in vitro tube formation and
endothelial cell proliferation.
Cancer Lett. 2007 Mar 5; [Epub ahead of print]
PMID: 17343983 [PubMed - as supplied by publisher]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=17343983>

5:  De Vecchi E, Drago L.
[Propolis antimicrobial activity: what's new?]
Infez Med. 2007 Mar;15(1):7-15. Italian.
PMID: 17515670 [PubMed - in process]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=17515670>

6:  Silici S, Koc AN.
Comparative study of in vitro methods to analyse the antifungal
activity of propolis against yeasts isolated from patients with
superficial mycoses.
Lett Appl Microbiol. 2006 Sep;43(3):318-24. Erratum in: Lett Appl
Microbiol.
2006 Oct;43(4):467.
PMID: 16910939 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16910939>

7:  Paulino N, Teixeira C, Martins R, Scremin A, Dirsch VM, Vollmar
AM, Abreu SR, de Castro SL, Marcucci MC.
Evaluation of the analgesic and anti-inflammatory effects of a
Brazilian green propolis.
Planta Med. 2006 Aug;72(10):899-906. Epub 2006 Aug 10.
PMID: 16902858 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16902858>

8:  Quiroga EN, Sampietro DA, Soberon JR, Sgariglia MA, Vattuone MA.
Propolis from the northwest of Argentina as a source of antifungal
principles.
J Appl Microbiol. 2006 Jul;101(1):103-10.
PMID: 16834596 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16834596>

9:  Speciale A, Costanzo R, Puglisi S, Musumeci R, Catania MR, Caccamo
F, Iauk L.
Antibacterial activity of propolis and its active principles alone
and in combination with macrolides, beta-lactams and fluoroquinolones
against microorganisms responsible for respiratory infections.
J Chemother. 2006 Apr;18(2):164-71.
PMID: 16736885 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16736885>

10:  Bruschi ML, Lara EH, Martins CH, Vinholis AH, Casemiro LA,
Panzeri H, Gremiao MP.
Preparation and antimicrobial activity of gelatin microparticles
containing propolis against oral pathogens.
Drug Dev Ind Pharm. 2006 Feb;32(2):229-38.
PMID: 16537203 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16537203>

11:  Khalil ML.
Biological activity of bee propolis in health and disease.
Asian Pac J Cancer Prev. 2006 Jan-Mar;7(1):22-31. Review.
PMID: 16629510 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16629510>

12:  Scazzocchio F, D'Auria FD, Alessandrini D, Pantanella F.
Multifactorial aspects of antimicrobial activity of propolis.
Microbiol Res. 2006;161(4):327-33. Epub 2006 Jan 19.
PMID: 16427259 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16427259>

13:  Orsolic N, Saranovic AB, Basic I.
Direct and indirect mechanism(s) of antitumour activity of propolis
and its polyphenolic compounds.
Planta Med. 2006 Jan;72(1):20-7.
PMID: 16450291 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16450291>

14:  Kosalec I, Pepeljnjak S, Bakmaz M, Vladimir-Knezevic S.
Flavonoid analysis and antimicrobial activity of commercially
available propolis products.
Acta Pharm. 2005 Dec;55(4):423-30.
PMID: 16375832 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16375832>

15:  Orsolic N, Basic I.
Antitumor, hematostimulative and radioprotective action of
water-soluble derivative of propolis (WSDP).
Biomed Pharmacother. 2005 Dec;59(10):561-70. Epub 2005 Aug 10.
PMID: 16202559 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16202559>

16:  Jin UH, Chung TW, Kang SK, Suh SJ, Kim JK, Chung KH, Gu YH,
Suzuki I, Kim CH.
Caffeic acid phenyl ester in propolis is a strong inhibitor of matrix
metalloproteinase-9 and invasion inhibitor: isolation and
identification.
Clin Chim Acta. 2005 Dec;362(1-2):57-64. Epub 2005 Jul 6.
PMID: 16004979 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16004979>

17:  Ozkul Y, Silici S, Eroglu E.
The anticarcinogenic effect of propolis in human lymphocytes culture.
Phytomedicine. 2005 Nov;12(10):742-7.
PMID: 16323293 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16323293>

18:  Orsolic N, Basic I.
Water-soluble derivative of propolis and its polyphenolic compounds
enhance tumoricidal activity of macrophages.
J Ethnopharmacol. 2005 Oct 31;102(1):37-45.
PMID: 16054317 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16054317>

19:  Orsolic N, Terzic S, Mihaljevic Z, Sver L, Basic I.
Effects of local administration of propolis and its polyphenolic
compounds on tumor formation and growth.
Biol Pharm Bull. 2005 Oct;28(10):1928-33.
PMID: 16204948 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16204948>

20:  Silici S, Koc NA, Ayangil D, Cankaya S.
Antifungal activities of propolis collected by different races of
honeybees against yeasts isolated from patients with superficial
mycoses.
J Pharmacol Sci. 2005 Sep;99(1):39-44. Epub 2005 Sep 1.
PMID: 16141640 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16141640>

21:  Fernandes Junior A, Balestrin EC, Betoni JE, Orsi Rde O, da Cunha
Mde L, ontelli AC.
Propolis: anti-Staphylococcus aureus activity and synergism with
antimicrobial drugs.
Mem Inst Oswaldo Cruz. 2005 Aug;100(5):563-6. Epub 2005 Sep 15.
PMID: 16184236 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16184236>

22:  Santos VR, Pimenta FJ, Aguiar MC, do Carmo MA, Naves MD, Mesquita
RA.
Oral candidiasis treatment with Brazilian ethanol propolis extract.
Phytother Res. 2005 Jul;19(7):652-4.
PMID: 16161031 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16161031>

23:  Sforcin JM, Orsi RO, Bankova V.
Effect of propolis, some isolated compounds and its source plant on
antibody production.
J Ethnopharmacol. 2005 Apr 26;98(3):301-5.
PMID: 15814263 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15814263>

24:  Orsolic N, Kosalec I, Basic I.
Synergistic antitumor effect of polyphenolic components of water
soluble derivative of propolis against Ehrlich ascites tumour.
Biol Pharm Bull. 2005 Apr;28(4):694-700.
PMID: 15802812 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15802812>

25:  Takagi Y, Choi IS, Yamashita T, Nakamura T, Suzuki I, Hasegawa T,
Oshima M, Gu YH.
Immune activation and radioprotection by propolis.
Am J Chin Med. 2005;33(2):231-40.
PMID: 15974482 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15974482>

26:  Orsolic N, Knezevic AH, Sver L, Terzic S, Basic I.
Immunomodulatory and antimetastatic action of propolis and related
polyphenolic compounds.
J Ethnopharmacol. 2004 Oct;94(2-3):307-15.
PMID: 15325736 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15325736>

27:  Melliou E, Chinou I.
Chemical analysis and antimicrobial activity of Greek propolis.
Planta Med. 2004 Jun;70(6):515-9.
PMID: 15229802 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15229802>

28:  Ugur A, Arslan T.
An in vitro study on antimicrobial activity of propolis from Mugla
province of Turkey.
J Med Food. 2004 Spring;7(1):90-4.
PMID: 15117559 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15117559>

29:  Salomao K, Dantas AP, Borba CM, Campos LC, Machado DG, Aquino
Neto FR, de
Castro SL.
Chemical composition and microbicidal activity of extracts from
Brazilian and Bulgarian propolis.
Lett Appl Microbiol. 2004;38(2):87-92.
PMID: 14746537 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=14746537>

30:  El-khawaga OA, Salem TA, Elshal MF.
Protective role of Egyptian propolis against tumor in mice.
Clin Chim Acta. 2003 Dec;338(1-2):11-6.
PMID: 14637260 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=14637260>

31:  Paulino N, Dantas AP, Bankova V, Longhi DT, Scremin A, de Castro
SL, Calixto JB.
Bulgarian propolis induces analgesic and anti-inflammatory effects in
mice and inhibits in vitro contraction of airway smooth muscle.
J Pharmacol Sci. 2003 Nov;93(3):307-13.
PMID: 14646248 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=14646248>

32:  D'Auria FD, Tecca M, Scazzocchio F, Renzini V, Strippoli V.
Effect of propolis on virulence factors of Candida albicans.
J Chemother. 2003 Oct;15(5):454-60.
PMID: 14598937 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=14598937>

33:  Akao Y, Maruyama H, Matsumoto K, Ohguchi K, Nishizawa K, Sakamoto
T, Araki Y, Mishima S, Nozawa Y.
Cell growth inhibitory effect of cinnamic acid derivatives from
propolis on human tumor cell lines.
Biol Pharm Bull. 2003 Jul;26(7):1057-9.
PMID: 12843641 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12843641>

34:  Kartal M, Yildiz S, Kaya S, Kurucu S, Topcu G.
Antimicrobial activity of propolis samples from two different regions
of Anatolia.
J Ethnopharmacol. 2003 May;86(1):69-73.
PMID: 12686444 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12686444>

35:  Orsolic N, Basic I.
Immunomodulation by water-soluble derivative of propolis: a factor of
antitumor reactivity.
J Ethnopharmacol. 2003 Feb;84(2-3):265-73.
PMID: 12648825 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12648825>

36:  Stepanovic S, Antic N, Dakic I, Svabic-Vlahovic M.
In vitro antimicrobial activity of propolis and synergism between
propolis and antimicrobial drugs.
Microbiol Res. 2003;158(4):353-7.
PMID: 14717457 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=14717457>

37:  Orsolic N, Sver L, Terzic S, Tadic Z, Basic I.
Inhibitory effect of water-soluble derivative of propolis and its
polyphenolic compounds on tumor growth and metastasizing ability: a
possible mode of antitumor action.
Nutr Cancer. 2003;47(2):156-63.
PMID: 15087268 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=15087268>

38:  Borrelli F, Maffia P, Pinto L, Ianaro A, Russo A, Capasso F,
Ialenti A.
Phytochemical compounds involved in the anti-inflammatory effect of
propolis extract.
Fitoterapia. 2002 Nov;73 Suppl 1:S53-63.
PMID: 12495710 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12495710>

39:  Russo A, Longo R, Vanella A.
Antioxidant activity of propolis: role of caffeic acid phenethyl
ester and galangin.
Fitoterapia. 2002 Nov;73 Suppl 1:S21-9.
PMID: 12495706 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12495706>

40:  Castaldo S, Capasso F.
Propolis, an old remedy used in modern medicine.
Fitoterapia. 2002 Nov;73 Suppl 1:S1-6. Review.
PMID: 12495704 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12495704>

41:  Suzuki I, Hayashi I, Takaki T, Groveman DS, Fujimiya Y.
Antitumor and anticytopenic effects of aqueous extracts of propolis
in combination with chemotherapeutic agents.
Cancer Biother Radiopharm. 2002 Oct;17(5):553-62.
PMID: 12470425 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12470425>

42:  Rossi A, Ligresti A, Longo R, Russo A, Borrelli F, Sautebin L.
The inhibitory effect of propolis and caffeic acid phenethyl ester on
cyclooxygenase activity in J774 macrophages.
Phytomedicine. 2002 Sep;9(6):530-5.
PMID: 12403162 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12403162>

43:  Song YS, Park EH, Jung KJ, Jin C.
Inhibition of angiogenesis by propolis.
Arch Pharm Res. 2002 Aug;25(4):500-4.
PMID: 12214863 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12214863>

44:  Banskota AH, Nagaoka T, Sumioka LY, Tezuka Y, Awale S, Midorikawa
K, Matsushige K, Kadota S.
Antiproliferative activity of the Netherlands propolis and its active
principles in cancer cell lines.
J Ethnopharmacol. 2002 Apr;80(1):67-73.
PMID: 11891088 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11891088>

45:  Santos FA, Bastos EM, Uzeda M, Carvalho MA, Farias LM, Moreira
ES, Braga FC.
Antibacterial activity of Brazilian propolis and fractions against
oral anaerobic bacteria.
J Ethnopharmacol. 2002 Apr;80(1):1-7.
PMID: 11891080 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11891080>

46:  Murad JM, Calvi SA, Soares AM, Bankova V, Sforcin JM.
Effects of propolis from Brazil and Bulgaria on fungicidal activity
of macrophages against Paracoccidioides brasiliensis.
J Ethnopharmacol. 2002 Mar;79(3):331-4.
PMID: 11849837 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11849837>

47:  Martins RS, Pereira ES Jr, Lima SM, Senna MI, Mesquita RA, Santos
VR.
Effect of commercial ethanol propolis extract on the in vitro growth
of Candida albicans collected from HIV-seropositive and
HIV-seronegative Brazilian patients with oral candidiasis.
J Oral Sci. 2002 Mar;44(1):41-8.
PMID: 12058869 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12058869>

48:  Chen YJ, Shiao MS, Hsu ML, Tsai TH, Wang SY.
Effect of caffeic acid phenethyl ester, an antioxidant from propolis,
on inducing apoptosis in human leukemic HL-60 cells.
J Agric Food Chem. 2001 Nov;49(11):5615-9.
PMID: 11714368 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11714368>

49:  Ota C, Unterkircher C, Fantinato V, Shimizu MT.
Antifungal activity of propolis on different species of Candida.
Mycoses. 2001 Nov;44(9-10):375-8.
PMID: 11766101 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11766101>

50:  Drago L, Mombelli B, De Vecchi E, Fassina MC, Tocalli L, Gismondo
MR.
In vitro antimicrobial activity of propolis dry extract.
J Chemother. 2000 Oct;12(5):390-5. Erratum in: J Chemother 2001
Feb;13(1):102.
PMID: 11128558 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11128558>

51:  Velikova M, Bankova V, Sorkun K, Houcine S, Tsvetkova I,
Kujumgiev A.
Propolis from the Mediterranean region: chemical composition and
antimicrobial activity.
Z Naturforsch [C]. 2000 Sep-Oct;55(9-10):790-3.
PMID: 11098832 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=11098832>

52:  Vynograd N, Vynograd I, Sosnowski Z.
A comparative multi-centre study of the efficacy of propolis,
acyclovir and placebo in the treatment of genital herpes (HSV).
Phytomedicine. 2000 Mar;7(1):1-6.
PMID: 10782483 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=10782483>

53:  Hegazi AG, Abd El Hady FK, Abd Allah FA.
Chemical composition and antimicrobial activity of European propolis.
Z Naturforsch [C]. 2000 Jan-Feb;55(1-2):70-5.
PMID: 10739103 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=10739103>

54:  Cafarchia C, De Laurentis N, Milillo MA, Losacco V, Puccini V.
Antifungal activity of Apulia region propolis.
Parassitologia. 1999 Dec;41(4):587-90.
PMID: 10870567 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=10870567>

55:  Kujumgiev A, Tsvetkova I, Serkedjieva Y, Bankova V, Christov R,
Popov S.
Antibacterial, antifungal and antiviral activity of propolis of
different geographic origin.
J Ethnopharmacol. 1999 Mar;64(3):235-40.
PMID: 10363838 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=10363838>

56:  de Campos RO, Paulino N, da Silva CH, Scremin A, Calixto JB.
Anti-hyperalgesic effect of an ethanolic extract of propolis in mice
and rats.
J Pharm Pharmacol. 1998 Oct;50(10):1187-93.
PMID: 9821669 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=9821669>

57:  Burdock GA.
Review of the biological properties and toxicity of bee propolis
(propolis).
Food Chem Toxicol. 1998 Apr;36(4):347-63. Review.
PMID: 9651052 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=9651052>

58:  Kimoto T, Arai S, Kohguchi M, Aga M, Nomura Y, Micallef MJ,
Kurimoto M, Mito K.
Apoptosis and suppression of tumor growth by artepillin C extracted
from Brazilian propolis.
Cancer Detect Prev. 1998;22(6):506-15.
PMID: 9824373 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=9824373>

59:  Park YK, Koo MH, Abreu JA, Ikegaki M, Cury JA, Rosalen PL.
Antimicrobial activity of propolis on oral microorganisms.
Curr Microbiol. 1998 Jan;36(1):24-8.
PMID: 9405742 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=9405742>

60:  Ghaly MF, Ezzat SM, Sarhan MM.
Use of propolis and ultragriseofulvin to inhibit aflatoxigenic fungi.
Folia Microbiol (Praha). 1998;43(2):156-60.
PMID: 9721607 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=9721607>

61:  Mirzoeva OK, Calder PC.
The effect of propolis and its components on eicosanoid production
during the inflammatory response.
Prostaglandins Leukot Essent Fatty Acids. 1996 Dec;55(6):441-9.
PMID: 9014224 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=9014224>

62:  Tatefuji T, Izumi N, Ohta T, Arai S, Ikeda M, Kurimoto M.
Isolation and identification of compounds from Brazilian propolis
which enhance macrophage spreading and mobility.
Biol Pharm Bull. 1996 Jul;19(7):966-70.
PMID: 8839971 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=8839971>

63:  Ivanovska ND, Dimov VB, Bankova VS, Popov SS.
Immunomodulatory action of propolis. VI. Influence of a water soluble
derivative on complement activity in vivo.
J Ethnopharmacol. 1995 Jul 28;47(3):145-7.
PMID: 8569238 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=8569238>

64:  Amoros M, Lurton E, Boustie J, Girre L, Sauvager F, Cormier M.
Comparison of the anti-herpes simplex virus activities of propolis
and 3-methyl-but-2-enyl caffeate.
J Nat Prod. 1994 May;57(5):644-7.
PMID: 8064297 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=8064297>

65:  Khayyal MT, el-Ghazaly MA, el-Khatib AS.
Mechanisms involved in the antiinflammatory effect of propolis
extract.
Drugs Exp Clin Res. 1993;19(5):197-203.
PMID: 7513636 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=7513636>

66:  Dumitrescu M, Crisan I, Esanu V.
[The mechanism of the antiherpetic action of an aqueous propolis
extract. II.
The action of the lectins of an aqueous propolis extract]
Rev Roum Virol. 1993 Jan-Jun;44(1-2):49-54. French.
PMID: 8043477 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=8043477>

67:  Amoros M, Simoes CM, Girre L, Sauvager F, Cormier M.
Synergistic effect of flavones and flavonols against herpes simplex
virus type 1 in cell culture. Comparison with the antiviral activity
of propolis.
J Nat Prod. 1992 Dec;55(12):1732-40.
PMID: 1338212 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=1338212>

68:  Dumitrescu M, Esanu V, Crisan I.
[The mechanisms of the antiherpetic action of aqueous propolis
extracts. I. The antioxidant action on human fibroblast cultures]
Rev Roum Virol. 1992 Jul-Dec;43(3-4):165-73. French.
PMID: 1339205 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=1339205>

69:  Serkedjieva J, Manolova N, Bankova V.
Anti-influenza virus effect of some propolis constituents and their
analogues (esters of substituted cinnamic acids).
J Nat Prod. 1992 Mar;55(3):294-302.
PMID: 1593279 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=1593279>

70:  Dimov V, Ivanovska N, Bankova V, Popov S.
Immunomodulatory action of propolis: IV. Prophylactic activity
against gram-negative infections and adjuvant effect of the
water-soluble derivative.
Vaccine. 1992;10(12):817-23.
PMID: 1455907 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=1455907<

71:  Dobrowolski JW, Vohora SB, Sharma K, Shah SA, Naqvi SA, Dandiya
PC.
Antibacterial, antifungal, antiamoebic, antiinflammatory and
antipyretic studies on propolis bee products.
J Ethnopharmacol. 1991 Oct;35(1):77-82. No abstract available.
PMID: 1753797 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=1753797>

72: Grange JM, Davey RW.
Antibacterial properties of propolis (bee glue).
J R Soc Med. 1990 Mar;83(3):159-60. Review.
PMID: 2182860 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=2182860>
<http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1292560>
(free full text)

73:  Brumfitt W, Hamilton-Miller JM, Franklin I.
Antibiotic activity of natural products: 1. Propolis.
Microbios. 1990;62(250):19-22.
PMID: 2110610 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=2110610>

74:  Paintz M, Metzner J.
On the local anaesthetic action of propolis and some of its
constituents.
Pharmazie. 1979 Dec;34(12):839-41.
PMID: 545354 [PubMed - indexed for MEDLINE]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=545354>

Best wishes, uncle sally.
I hope it works for you.
J

It's not a bad assumption to make that anyone having chemo and / or dxrt to
head and neck and develops a sore mouth / throat may have thrush and take
mycostatin anyway. Your GP sounds very sensible to me.
MIKE

I have a very low threshold to prescribing antifungals to a any cancer
patient