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Medical Forum / Diseases and Disorders / Cancer / December 2006NSCLC changing to SCLC
Anybody ever hear of this? Mark > Anybody ever hear of this? > > Mark A possible explanation is a change in the pathologic classification of SCLC, in which some tumors which would have been called SCLC in the past are now identified as non-small-cell lung cancer (NSCLC) with neuroendocrine features. > Anybody ever hear of this? > > Mark Mixed cancers are not that uncommon. > "Mark" <cirone@comcast.net> wrote in message > > Anybody ever hear of this? > > > > Mark > > Mixed cancers are not that uncommon. Steph, Can being on treatments _longterm_ cause another cancer OR a new cancer and/or more aggressive cancer to start or an existing cancer to become more aggressive ? (re: dna damage to cells) J >> "Mark" <cirone@comcast.net> wrote in message >> > Anybody ever hear of this? [quoted text clipped - 8 lines] > more aggressive ? (re: dna damage to cells) > J Not really Steph, Her Dr.'s are telling her it's morphed into SCLC. Not a new cancer. Have you seen this behavior before and if you have what treatments have been most successful? Mark >> Anybody ever hear of this? >> >> Mark > > Mixed cancers are not that uncommon. > Steph, > [quoted text clipped - 3 lines] > > Mark Nobody can be dogmatic about "morphing" Likely it was a mixed cancer. The prognosis depends on the most aggressive elements - the scslc - and should be treated as such Steph, They biopsied her lung in Oct 2005 and found it to be NSCLC. Are you suggesting that the primary could be this and the mets back then SCLC? She had a small lesion in her brain they took care of with SRS. After intitial chemo, she disn't have disease progression for eight months. Her brain RI remains clean. Are these findings consistant with SCLC? Also, she's having an MRI of her hip and femur this week to confirm PET results of mets to those areas. If this is SCLC and it's in those places, what should we expect and is RT the only treatment? Mark >> Steph, >> [quoted text clipped - 7 lines] > Likely it was a mixed cancer. The prognosis depends on the most aggressive > elements - the scslc - and should be treated as such > Steph, > [quoted text clipped - 3 lines] > intitial chemo, she disn't have disease progression for eight months. Her > brain RI remains clean. Are these findings consistant with SCLC? All biopsies are subject to potential sampling error. It could have been a mixed tumour all along, it could be a new lung cancer. In terms of management, it's really academic. > Also, she's having an MRI of her hip and femur this week to confirm PET > results of mets to those areas. If this is SCLC and it's in those places, > what should we expect and is RT the only treatment? > > Mark sclc or non-sclc, radiotherapy is the correct treatment |
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