We have had men post from time to time but no male breast cancer patients at
present.

Here are some links
http://www.johnwnickfoundation.org/index.html

http://www.askmen.com/sports/health/18_mens_health.html

http://www.cancerhelp.org.uk/help/default.asp?page=5075

http://www.y-me.org/information/male_breast_cancer/breast_cancer_in_men.php

Has a match program for peer support.

At one time in the history of medicine .. bloodletting / 'iron
reduction therapy' was the ONLY form of treatment .. which worked for
**gynecomastia**.

-------------------------------------------------------------------------------------
http://www.cdc.gov/ncbddd/hemochromatosis/training/clinical_features/clinical_ex
pression.htm

Hypogonadism occurs in both sexes and may antedate other clinical
features. Manifestations include loss of libido, impotence, amenorrhea,
testicular atrophy, **gynecomastia**., and sparse body hair.

-------------------------------------------------------------------------------------

The advent of hormone therapy paved the way for its' .. demise.

Luckily .. the solution seems to be the TARGETING of the iron levels in
the body as per recent findings of .. chemotherapy resistant cancer ..
RESPONDING to iron binding substances.

http://www.pnas.org/cgi/content/abstract/0604979103v1

This article shows the incidence of breast cancer in men with regards
to the aforementioned gynecomastia.

---------------------------------------------------------------------------------
http://www.phoenix5.org/Basics/treatsides/gyneBCaMen.html

Gynecomastia & breast cancer?

Though often overlooked, breast cancer afflicts men too

<<snip>>
In younger males and older men, breast cancer is typically associated
with gynecomastia, a condition that results in overdeveloped breasts.
<<snip>>

---------------------------------------------------------------------------------

Soooo .. low iron / restricted iron / vegetarian diet .. and the
TARGETING of iron with all the natural iron targeting substances that
the mind can muster ..

Resveratrol would be a good place to start .. sulpuraphane containing
substances .. etc, etc, etc ..

Those high .. phosphate groups .. seem to be showing some .. efficacy
..

Such as .. phytic acid ..

Rice bran oil .. massaged four times a day .. theoretically ..  is a
VERY .. sound .. heroic .. effort ..

http://herbivore.7h.com/cancerpost.html

---------------------------------------------------------------------------------

Iron reduction therapy ..

http://www.pnas.org/cgi/content/abstract/0604979103v1

A class of iron chelators with a wide spectrum of potent antitumor
activity that overcomes resistance to chemotherapeutics

---------------------------------------------------------------------------------

Titre du document / Document title
Desferoxamine (DFO) - mediated iron chelation: rationale for a novel
approach to therapy for brain cancer
Auteur(s) / Author(s)
DAYANI Pouya N. (1) ; BISHOP Maria C. (2) ; BLACK Keith (3) ; ZELTZER
Paul M. (3) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Northwestern University Medical School, Chicago, IL, ETATS-UNIS
(2) University of Arizona Cancer Center and Southern Arizona Veterans
Administration Health Care System, Tucson, AZ, ETATS-UNIS
(3) Maxine Dunitz Neurosurgical Institute, Cedars Sinai Medical Center,
Los Angeles, CA, ETATS-UNIS

Résumé / Abstract
Iron homeostasis is crucial to normal cell metabolism, and its
deficiency or excess is associated with numerous disease states. The
association of increased iron load with cancer may be due to several
factors including free radical production, reduction of the body's
protective mechanism to combat oxidative stress, inhibition of immune
systems, inhibition of essential nutrient functions, facilitation of
cancer growth, suppression of antitumor actions of macrophages, and
lowering of the ratio of T4-T8 positive lymphocytes. Antiproliferative
effects of desferoxamine (DFO) both in vitro and in viva are mediated
by an intracellular pool of iron that is necessary for DNA synthesis
rather than prevention of iron uptake from transferrin. Several
clinical studies have shown it to have antitumor activity in the
treatment of neuroblastoma, leukemia, bladder carcinoma, and
hepatocellular carcinoma. Human neural tumor cells are susceptible to
the effects of DFO. Continued study of DFO is necessary to further
elucidate its antineoplastic profile and its use as an adjunct to
current chemotherapy regimens. Given the lack of satisfactory treatment
of central nervous system neoplasms, DFO could serve as an important
tool in the management of such cancers.
Revue / Journal Title
Journal of neuro-oncology  (J. neuro-oncol.)  ISSN 0167-594X
Source / Source
2004, vol. 67, no3, pp. 367-377 [11 page(s) (article)] (63 ref.)
Langue / Language
Anglais

Editeur / Publisher
Kluwer, Dordrecht, PAYS-BAS (1983) (Revue)

Mots-clés anglais / English Keywords
Autonomic neuropathy ; Central nervous system ; Transferrin ;
Chemotherapy ; Encephalon ; Nervous system diseases ; Treatment ;
Therapy ; Neuroblastoma ; Surgical approach ; Iron ; Malignant tumor ;
Mots-clés français / French Keywords
Système nerveux sympathique pathologie ; Système nerveux central ;
Transferrine ; Chimiothérapie ; Encéphale ; Système nerveux
pathologie ; Traitement ; Thérapie ; Neuroblastome ; Voie abord ; Fer
; Tumeur maligne ;

002b17 ;
Mots-clés espagnols / Spanish Keywords
Sistema nervioso simpático patología ; Sistema nervioso central ;
Transferrina ; Quimioterapia ; Encéfalo ; Sistema nervioso patología
; Tratamiento ; Terapia ; Neuroblastoma ; Vía abordaje ; Hierro ;
Tumor maligno ;
Mots-clés d'auteur / Author Keywords
brain tumors ; chemotherapy ; desferoxamine ; iron chelation ;
neuroblastoma ; transferrin receptor ;
Localisation / Location
INIST-CNRS, Cote INIST : 20812, 35400011011807.0130

Copyright 2006 INIST-CNRS. All rights reserved

----------------------------------------------------------------------------------------------------

Iron / metastasis of oral squamous cell carcinoma {cancer]

<<snip>>
Conclusion: This result indicated that iron might play a role in
metastasis of oral squamous cell carcinoma.
<<snip>>

2406 Iron Regulates MMP-9 Expression in Oral Squamous Cell Carcinoma
R. KAOMONGKOLGIT1, P. CHEEPSUNTHORN2, P. PAVASANT1, and N.
SANCHAVANAKIT1, 1Chulalongkorn University, Faculty of Dentistry,
Bangkok, Thailand, 2Chulalongkorn University, Faculty of Medicine,
Bangkok, Thailand
Objective: This study aims to investigate the effect of iron on the
modulation of MMP-9 expression in oral squamous carcinoma cells.
Methods: Human oral squamous carcinoma cell line derived from the
metastatic site,OM-2, was treated with Ferric ammonium citrate (FAC)
ranging from 5 to 50 ug/ml. Cytotoxicity of FAC was tested by MTT
assay. The expression of MMP-9 was analyzed by reverse transcription
polymerase chain reaction. Conditioned medium was collected for
examination of MMP-9 secretion and activation by zymography. Inhibitors

of ERK, JNK and p38 kinase were used for determination of the
intracellular signaling pathway induced by FAC. Results: The toxicity
of FAC was observed at 10 ug/ml. Application of FAC at 5 ug/ml
increased the expression of MMP-9 in both mRNA and protein levels.
However, the activation of MMP-9 was not observed. Addition of ERK
Inhibitor could inhibit the expression of MMP-9 induced by FAC.
Conclusion: This result indicated that iron might play a role in
metastasis of oral squamous cell carcinoma.

Seq #192 - Cancer 2
3:30 PM-4:30 PM, Friday, 30 June 2006 Brisbane Convention & Exhibition
Centre Exhibit Hall 1
Back to the Oral Medicine & Pathology Program
Back to the IADR General Session & Exhibition (June 28 - July 1,

Who loves ya.
Tom

Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com

Man Is A Herbivore!
http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk