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Medical Forum / Diseases and Disorders / Cancer / August 2006

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The M protein

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Bill Thomas,Cardiff,UK - 29 Aug 2006 21:48 GMT
Question from a newbie.I carry the M protein.
Monoclonal Gammopathy of Undetermined Significance.
It is a precursor of Myeloma and similar,with a 24% chance of getting it .
The odds shorten with age.The haematopathologist is waiting
to see if it gets any worse before doing anything, which I find abhorrent.
Is there anyone out there with knowledge of this disease
who can give me a lead on lifestyle changes or whatever
to help prevent its development.(After seeing the Doc.)
All replies acknowledged.
Thanks.

Bill Thomas,
Cardiff, UK.
J - 30 Aug 2006 00:22 GMT
> Question from a newbie.I carry the M protein.
> Monoclonal Gammopathy of Undetermined Significance.
[quoted text clipped - 9 lines]
> Bill Thomas,
> Cardiff, UK.

Hi Bill,
I'm sure your doctor will tell you that there's nothing to be done but get on
with your life, live as healthy as possible and follow his/her instructions
for monitoring.
Hopefully it's much ado about nothing. In other words, it won't develop into
anything later.

Here's what the myeloma foundation says about it
http://www.multiplemyeloma.org/about_myeloma/2.06.asp
MGUS is a common condition where a monoclonal protein is present.
However, there are no symptoms, other criteria for myeloma diagnosis are
absent, and no cause for the increased protein can be identified.
MGUS occurs in about 1% of the general population and in about 3% of normal
individuals over 70 years of age.
MGUS itself is harmless but over many years approximately 16% of individuals
with MGUS will progress to a malignant plasma cell disorder.
Characteristics:
 Serum M protein <3 g/dL
 Bone marrow plasma cells <10%
 Absence of anemia, renal failure, hypercalcemia, lytic bone lesions
 Disease Management - observation

There's a free phone helpline (UK) here
http://www.cancerbackup.org.uk/Cancertype/Myeloma
if you wish another opinion.
Good luck.
J
sam - 30 Aug 2006 20:36 GMT
>> Question from a newbie.I carry the M protein.

>> Bill Thomas,
>> Cardiff, UK.
[quoted text clipped - 26 lines]
> Good luck.
> J

Thank you J. I shall follow up the link.
Steph - 30 Aug 2006 03:14 GMT
> Question from a newbie.I carry the M protein.
> Monoclonal Gammopathy of Undetermined Significance.
[quoted text clipped - 9 lines]
> Bill Thomas,
> Cardiff, UK.

Your haematologist is giving you good advice.
sam - 30 Aug 2006 20:33 GMT
> "Bill Thomas,Cardiff,UK" <Oldbill@splott.uk> wrote in message
>
[quoted text clipped - 4 lines]
>
> Your haematologist is giving you good advice.

Thank you, Steph. Your reply is acknowledged.
 
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