Does anyone have any experience takin melatonin and leukemia recovery? Ive
done a lot of googling and it sounds promising. My girlfreind has just been
told she is in full remission from leukemia but is scared of it returning. I
discovered the following:-

Melatonin: an essential factor for the treatment and recovery from leukemia
and cancer.

In addition to its endocrine effects, other non-endocrine functions have
been attributed to the pineal gland, such as those displayed on the CNS (1).
And yet habenular nuclei stimulation causes an increase in blood platelet
count (2), in the same manner as injected Melatonin, particularly in the
case of splenechtomized and/or epinephrectomized ratas. According to our
belief, the platelets, and Melatonin too, play an essential role in leukemia
etiopathogenesis; we have therefore assayed the effects of Melatonin
treatment on leukemia and cancer patients for seven years, with the
following results:

1) It is practically impossible to eradicate leukemia or cancer without
Melatonin treatment.

2) Melatonin is a necessary, though by itself alone, not sufficient, remedy
for leukemia and cancer cure.

3) A supporting action is often simultaneously required, that rests upon a
parallel use of ACTH, of anti-free-radical drugs, ADH, SRIF, PIF,
mineralcorticoids.

4) Melatonin may be administered by mouth, as well as parenteral route,
without any dangerous instant or late effect, even though the administering
is protracted for months or years.

5) Some leukemia patients have arbitrarly discontinued the Melatonin
therapy, without any trouble or relapse. That supports the convinction that
leukemia can be truly definetively healed.

6) The treatment does not generally entail, or only rarely, any
hospitalization, apart from a periodic blood analysis.

7) Myeloid, acute or chronic, leukemia has to be cured with significantly
lower dosages of Melatonin.

8) Good or excellent results have been reached in epithelial or connective
tissue tumors, where a steady yearslong equilibrium may be reached, which
allows a normal, or almost usual existence.

The mechanism Melatonin works with, is a monifold one. The main topics are
perhaps the inhibition of GH and prolactin secretion (3), and the impairment
of mitosis (4).

REFERENCES

1) Anton-Tay F., J.L. Diaz & A. Fernandes-Guardiola: Life Sci., 1971, 10,
841-850;

2) Di Bella L., M.T. Rossi & G. Scalera: Progr. Brain Res., 1979, 52,
475-478;

3) Kostyo J.L. & O. Jsaksson: Int. Rev. Physiol., 1977, 13, 255-274;

4) Banerjee S. & L. Margulis: Exp. Cell. Res., 1973, 78, 314-318.

L. Di Bella, M.T. Rossi, G. Scalera and L. Gualano

(Cattedra di Fisiologia Generale, Università di Modena)