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Medical Forum / Diseases and Disorders / Cancer / July 2006

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RE. Paclitaxol

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Jonathan Law - 03 Jul 2006 04:52 GMT
Hi there, I was wondering if anyone out there has had paclitaxol chemo
therapy, and if so, how it has affected you?  My mum has started it and has
been knocked for a six.  Being told she needs this once a week for the next
six months for the treatment of secondary cancer in the liver (had breast
cancer) is a very daunting thought.  Would love some feedback from others
who have been there.
Thanks in advance
Barbara
J - 03 Jul 2006 10:14 GMT
> Hi there, I was wondering if anyone out there has had paclitaxol chemo
> therapy, and if so, how it has affected you?  My mum has started it and has
[quoted text clipped - 4 lines]
> Thanks in advance
> Barbara

Hello Barbara and welcome to alt.support.cancer.
I'm sorry to hear what's brought you here.
I'm also surprised that a doctor in Australia has suggested chemo.

Once breast (or any of the common epithelial cell) cancer hits a vital organ
like the liver, one must ask some serious questions.

Bear with me, please, for what might appear (to you) to be strange questions.

What is your mother treating? spots on part (or all lobes?) of her liver or a
painful mass?

What does your mother hope to accomplish with chemo?  Gain time?
Shrink a painful mass? There's more effective ways of palliating such -
radiation therapy without the toxic effects (to the whole body) of chemo.

Please stay with us, while we talk about this.
J
alex - 03 Jul 2006 15:32 GMT
"> Hello Barbara and welcome to alt.support.cancer.
> I'm sorry to hear what's brought you here.
> I'm also surprised that a doctor in Australia has suggested chemo.
[quoted text clipped - 15 lines]
>
> Please stay with us, while we talk about this.

Hi Barbara,
I am a breast cancer survivor but don't have metastic disease like your
mother.  I have heard from my oncologists that unlike many cancers which is
often untreatable, many women can live along time with metastic breast
cancer sometimes decades. Alt.support. cancer. breast there are women who
are living with advanced breast cancer. Many women there can answer your
question regarding Pacitaxol. The readings, lectures, and oncologists I have
visited have all stated that advanced breast cancer is a chronic disease (
such as diabetes or heart disease) . According to Dr Love , when pain
(caused by the expanding liver pressing on the membrane that encases it)
becomes too difficult to tolerate, the liver may be radiated to shrink it.
Chemotherapy is usually used for liver metastases.

Susan Love, MD has a consumer level breast cancer book.
http://www.susanlovemd.com/
http://www.breastcancer.org/rcr_metas_idx.html

Would of caution, when seeking internet advice, remember the source of the
postings. Is the poster a cancer survivor?  Are they being touched by cancer
in a personal way?  If medical advice is being rendered are they a physician
?  Nurse ? Researcher? Remember your mom's health care team is the best
source since they can examine your mother.   Also your mom's complete
medical history is assessed.

This is a great place for support, but not a place for a clinical diagnosis
to be made.

 Alex
J - 03 Jul 2006 16:35 GMT
> I am a breast cancer survivor but don't have metastic disease like your
> mother.  I have heard from my oncologists that unlike many cancers which is
[quoted text clipped - 6 lines]
> (caused by the expanding liver pressing on the membrane that encases it)
> becomes too difficult to tolerate, the liver may be radiated to shrink it.

And that's what I wrote.

> Chemotherapy is usually used for liver metastases.

That's the American way.
You of all people - they kept sending your mother for more treatments and
<direct quotes from your previous posts> " every day she came back worse, it was
obvious the cancer was progressing, but not one person told us is was futile.
And believe me, I asked. This information was never shared with her or my family
instead we were lead to believe she may have some quality time even if it was a
few weeks or months"

And Pat, who despite having 5 different chemos (along with other treatments),
nothing stopped the cancer from appearing in her liver. She's in hospice now.

And Allan's wife's been on so many chemos now, she's got cumulative peripheral
neuropathy, on high dose pain medications, yet he and the doctor continue to
"plan her next treatment", and she has 4 bad days out of every 7 and the 7th is
the treatment day.  We never hear a peep out of her (never posts). it's always
him posting and he puts a positive spin on everything.  That's the American way.

J
alex - 03 Jul 2006 17:15 GMT
> And Pat, who despite having 5 different chemos (along with other
> treatments),
[quoted text clipped - 13 lines]
>
> J

Yes, it is the American way,  also the Finish and German way since they are
the ones who did the study on Taxol.  It must be the Australian way too
since it is being offered
http://www.breasthealth.com.au/types/metastaticoptions.html.

My mother died in 1993.... which is 13 years ago -cancer treatment has
changed.   My mother wanted the radiation treatment, it was her choice. In
hindsight I would have liked to have been more informed.  I don't know what
transpired behind closed doors.

Also it is the American way that  a complete history and clinical exam is
given before dispensing diagnosis and treatment plans.   I would hope that
other international communities support a clinical exam and treatment plan
in person, not on the internet by qualified health care personnel.
J - 03 Jul 2006 23:39 GMT
>  Yes, it is the American way,  also the Finish and German way since they are
> the ones who did the study on Taxol.  It must be the Australian way too
> since it is being offered
> http://www.breasthealth.com.au/types/metastaticoptions.html.

I'm not sure that web page is accurate for other reasons.

Well, here's what it says for liver (then it goes on to mention Herceptin).
J
4. If you have been diagnosed with cancer in your liver, you may be recommended
to have one or more of the following treatments:

   * Surgery may be used to remove cancer in the liver (if there is only one
small cancer). However, this is uncommon.
   * Pain relief involves drug and non-drug treatments such as muscle
relaxation.
   * Drugs for nausea.
   * Dietary management and drugs for weight loss and lack of appetite.
alex - 04 Jul 2006 05:37 GMT
> That's the American way.
> You of all people - they kept sending your mother for more treatments and
[quoted text clipped - 7 lines]
> was a
> few weeks or months"

I am really upset that my mother's story has been distorted.  I wonder how
different my mother's situation would have been treated in Canada.  Once you
have advance cancer do they just send you home to die?  Are palliative
treatments ignored?   I fail to see how the "American Way was at fault".

Here is the story of my mother's illness.

In 1993 my dad broke his hip  - age 88. My parents had to have their house
remodeled so they could live independently.  Both my parents came to live
with my family that summer. My mother was age 79- under a doctor's routine
care. She was still driving and completely functional working part time in
the town hall.

After living in my home for  over 3 months, my parents moved back to their
home 20 miles away. The second night they where home, I got a call from the
police that I needed to pick up my father since my mother passed out and
probably had a stroke.  By the time I got my father settled and  found some
one to look after him. I went to the hospital to see how my mother was
doing.  By that time I got to the hospital my mother was able to talk. They
did  not have the results of the CT Scan yet.... but she did have a lesion
on her brain and the doctor told me her xray was abnormal. After a
bronchoscopy the diagnosis of lung cancer was made.

Once again my parents came to live with me and my family.  This was very
hard since my Dad needed 24 hour care,  my husband and I both worked and my
children were school aged. My sister who was overseas came home and she
would transport my mother for radiation treatment.  About  2 weeks into
radiation treatment which was clearly palliative to prevent another stroke
like event which was under control with high dose steroids she had a massive
GI Bleed in my home.  Since it was Saturday AM - my children were home. For
those of you who haven't had the experience of a GI Bleed it is rather
dramatic in its presentation.....blood all over the place and the smell is
something you will never forget.  I felt , it would not be fair to my
children to have my mother home  with a GI Bleed. I knew at this point it
was the beginning of the end.  Remember 3 weeks ago my mother was driving
and fully functional.  I purposely called a private ambulance after calling
the oncall MD at my mother's local hospital. I explained the situation to
the doctor and he agreed to admit my mother for palliative care.  I choose a
private ambulance since my local ambulance would only take my mother to the
local hospital.  When the ambulance arrived, they feared my mother was dying
and would only take her to a local hospital.  By the time I got to the
hospital they were transfusing blood and was moving her to the ICU. The
local hospital had access to the radiation oncologist records since the
radiation treatment was taking place at that hospital. I remember paging a
colleague from the hospital (an oncologist) asking him for advice, he told
me that she may have some time since she was so recently diagnosed.  Once
the dust had settled, my mother was lucid, the decision was to discontinue
the blood transfusions and not have surgery to correct the GI Bleed.

When I had posted the reference to my mother and radiation therapy,  it was
in reference to radiation treatment (if my memory serves me correctly).   I
was upset that the radiation team, knew how fragile my mother's condition
was yet this was not communicate to the family. Palliative radiation for my
viewpoint did more harm then good.  I speculate that if she didn't have the
radiation, she may have had more quality time with the family and not
suffered the effects of radiation.  Remember I have responsibilities for my
children and aged father. My mother died in less than  6 weeks of diagnosis.
I asked to take a leave at work and they denied it, I applied for the family
leave act which got approved after my mother died.

Normally,  I would have just quit my position, but at the time my husband
was facing a possible lay off. Once again I felt the responsibility towards
my children to have a steady income and health insurance for them and was
working, being a caretaker to my father and children.
Thank God my husband was my partner in all this. Yes, this is the American
way, please share with me how the Canadian system would be superior ?  Does
Canada have a magic way of predicting illness?  Are all the doctors
wonderful communicators in Canada? Are you telling me that the radiation
doctor would have told us her palliative care was futile ? Please if you are
going to quote me , I tell the whole story.

Sorry, to be so long winded, but I feel the whole story needed to be told.
Obviously the cancer was very aggressive and was killing her.  She had a
very rapid decline every day after radiation to the brain. Radiation was not
kind to her.  My mother was very proud to be an American . Why do Americans
continually get bashed on this support group?

PS : My parents bills where fully cover with Medicare and their supplemental
insurance.
Emily - 04 Jul 2006 14:11 GMT
alex@noemail.com said...

[big snip]

> Why do Americans
> continually get bashed on this support group?

Are you sure that they do?  I was under the impression that the majority
of regulars here were American.  I certainly wouldn't bash the Americans
- I don't like the idea of having to pay for primary health care, but
maybe that's just because I've grown up knowing that I'll never have to
pay.  I don't say the NHS always gets it right (and you'll have noticed
that in my posts I always acknowledge its faults) but at least I have
the assurance that I don't need to find vast sums of money just to stay
alive.  That said, it's the SYSTEM in the States that worries me, not
the people.  Of the American people I've met or talked to, I can't think
of any I've not liked.  Same goes for the Canadians, French, Germans and
any of the other nations that the British traditionally 'hate'.  I've
met a lot of British folk I'd sooner not see again though...

Signature

Em

alex - 04 Jul 2006 16:10 GMT
"> Are you sure that they do?  I was under the impression that the majority
> of regulars here were American.  I certainly wouldn't bash the Americans
> - I don't like the idea of having to pay for primary health care, but
[quoted text clipped - 7 lines]
> any of the other nations that the British traditionally 'hate'.  I've
> met a lot of British folk I'd sooner not see again though...

First of all you do pay for your primary care through your taxes. Americans
pay a much lower tax rate. The question is do I want the government
dictating how my health care dollars should be spent.  Americans  feel that
health care is not an entitlement. It has been debated and polled , and we
do not want the government to manage our health care. Americans rather keep
the money and manage their own health care.  The Vast majority of Americans
are very happy with the health system.

The point of J's was that American's are over treated for cancer, ie that is
why she brought up my mother which I thought was very cruel.  My mother and
I were very close. It was a very painful time in my life. Imagine taking
care of your aged father, dying mother and having 2 school age children.
Steph continually bashes the way American oncologists treat patients The
oncologists I have seen are very hard working and dedicated, if their sole
motivation was money they would be in more lucrative field of medicine.  If
my past experience with Canadian doctors wasn't  so positive, I would be
afraid to travel to Canada.

You can not judge a health care system via the internet.  The bashers never
mention personal or first hand experiences like I have mentioned my daughter
traveling as a student in Australia was REFUSED care twice  for a high
impact  ankle injury. She now has had surgery ( fully covered by my health
plan) which is causing us financial hardship since she is unable to work (
not to mention the pain and suffering).  It really irks me since our health
insurance would have covered all costs, she had a credit card for payment if
they wanted their money upfront, AND I had to pay $500 dollars to the
Australian government for the non existent healthcare.  The hospital would
not even provide crutches. I think it is sinful.
My son is going to England next year for school, if he has any injury, he
will be on the next plane out of England. I do not trust your precious
system.  Although the University he is attending has a health clinic which
gives me some hope that he won't be treated so cruelly as my daughter.
Emily - 04 Jul 2006 17:23 GMT
alex@noemail.com said...
> My son is going to England next year for school, if he has any injury, he
> will be on the next plane out of England. I do not trust your precious
> system.  

Well thanks a bunch.
alex - 04 Jul 2006 17:28 GMT
> alex@noemail.com said...
>> My son is going to England next year for school, if he has any injury, he
>> will be on the next plane out of England. I do not trust your precious
>> system.
>>
> Well thanks a bunch.

If it was your child, what would you do? Oh I forget your system does not
cover travel, your child would be treated for free with my tax dollars...
not sent away and suffering.  Perhaps I was wrong comparing England to
Australia but they are sister systems.  Alex
J - 04 Jul 2006 17:36 GMT
> .  Perhaps I was wrong comparing England to
> Australia but they are sister systems.  Alex

http://www.arcadia.edu/cea/index.aspx?id=1664
Health and Insurance
All foreigners in Australia are required to have health insurance valid for use
in Australia before departing the US. CISI health insurance, provided by Arcadia
University to all participants, will usually cover these needs. This insurance
program operates on a reimbursement basis only.  Thus, all medical treatments,
doctor visits and medication MUST be paid for in cash at the time of treatment.
(Some doctors will accept credit card payments.)

You are required to keep all receipts and itemized statements to submit to CISI
insurance company for reimbursement. CISI forms explain how to attach your
receipts to the form and how to send the form and receipts directly to CISI.

Note: Be sure to plan ahead and budget for medical treatment and doctor
appointments. Extend your credit card limits so you can be sure you will have
the ability to cover any expenses required for treatment of common colds, flus,
dental problems, etc. You MUST see a doctor if you are feeling ill.

Visa Application Process
As a general rule, students do not need to submit a physical exam for their
visas. However, those students with a medical history or pre-existing condition,
or who are not US citizens, as well as any student who has traveled to certain
countries (including Japan, Spain and most of Latin America) will be required to
submit a medical exam and chest x-ray with their visa application. Contact the
Australian consulate in your jurisdiction for additional information.

Medical Services in Australia
The Arcadia University Australia staff have contacts for local physician
services to handle non-emergency situations such as colds, fevers, etc. Check
with the Arcadia Australia staff as to the arrangements you need to make.

According to the Australian government, you will need to check with a local
doctor if your medication or an appropriate alternative is available for supply
in Australia. If not, they will need to work with the government's Experimental
Drugs Section for an exemption. Ask for an original receipt to submit to your
insurance provider.

CISI insurance company will cover most doctor visits; consult your agreement.
Make copies of the receipts to keep for your records.

For emergency situations, there are major hospitals. You will be given a
comprehensive list of emergency numbers and more details about health and safety
during orientation.

Additional Resources

   * Mobility International has a useful checklist for students with chronic
health conditions, as well as other disability and health-related travel
materials:  http://www.miusa.org.
   * Australian Embassy in the US:  http://www.austemb.org
   * Australian Consular Information Sheet provides the US State Department's
updated travel information details, visa requirements and medical care news:
     http://travel.state.gov/travel/cis_pa_tw/cis/cis_954.html
alex - 04 Jul 2006 21:06 GMT
All university students in the US, where or not international are required
to have health insurance.

Point is my daughter had  a credit card which she could have charged over
20K, American Health insurance and Australian Health Insurance was denied
care in 2 major cities, Melbourne and Sydney.

If the same situation was reversed, an Australian presenting for treatment
at a emergency room, she would be a very rich women since it is against  the
law to refuse a person treatment.

Here is the handbook:

http://www.capaprograms.org/pdf_files/Sydney_Handbook_WEB.pdf

Which states the medical facilities are excellent.

PS my daughter leg wasn't sprained. she thought it was sprained, it was
fractured.
Emily - 04 Jul 2006 17:48 GMT
alex@noemail.com said...

> > alex@noemail.com said...
> >> My son is going to England next year for school, if he has any injury, he
[quoted text clipped - 4 lines]
>
> If it was your child, what would you do?

I'd see what the situation was before reacting.
alex - 04 Jul 2006 17:51 GMT
I did!!!!!!
I called our health insurance, I called the Australian  University ( and was
assure that the health care was not an issue). And provided her with a
credit card. I paid the Australian Health Care premium which according to
the Australian web page would cover any medical needs.   Our than writing
the prime minister I don't whatelse to do?

Who should I write to England to prevent this from happening again?
J - 04 Jul 2006 18:11 GMT
> I did!!!!!!
> I called our health insurance, I called the Australian  University ( and was
> assure that the health care was not an issue).

Find her university on the www..let's see what it says.
J
J - 04 Jul 2006 18:20 GMT
> "You can not judge a health care system via the internet.  The bashers never
> mention personal or first hand experiences like I have mentioned my daughter
> traveling as a student in Australia was REFUSED care twice  for a high
> impact  ankle injury.

She presented to ER reported a sprained ankle. "She thought she sprained her
ankle"
I've had 30 +/- sprained ankles over my lifetime and never (but once) even been
to a doctor and ER?  never would I bother ER with a sprained ankle.  My mother
was an RN. I know about RICE and I think I'd know if the pain continued too
long, what to do about it. University abroad, I'd do my homework first before
going.

I've been to the US a number of times (when much younger) and never planned
ahead, never thought what I would do if XX happened. Let this be a lesson to
anyone travelling, inquire and plan ahead.

Americans come up here for treatment or get access to care while here. Mode of
payment varies...
They come prepared with money.

Sprained ankle...  This is American
http://www.podiatrychannel.com/ankleinjuries/
Treatment usually involves RICE - rest, ice, compression, and elevation:
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may help to
reduce pain, swelling, and inflammation. Due to potentially severe
gastrointestinal and cardiovascular side effects, NSAIDs should only be used as
instructed.

In some cases, prolonged swelling caused by the formation of excessive scar
tissue occurs and the physician may request x-rays to check for small,
previously undetected bone fragments, or damage to the joints.

Most ankle strains and sprains heal in 2 to 6 weeks, with proper treatment.
Severe injuries may take as long as 12 weeks to heal and may require physical
therapy to restore full muscle balance and strength. Physical therapy may
involve stretching the Achilles tendon, as well as coordination and speed
exercises. During this time, the ankle may require taping or bracing to provide
support until full function is regained.

Patients who experience an ankle injury are at risk for recurrent injury during
and following recovery and should take precautions. Shoes that provide stability
and support are a prudent investment, and supplemental bracing with a specially
fitted elastic wrap may be recommended.

Surgery
Ankle sprains rarely require surgery [...]
So ER's don't do surgery for ankle scar tissue. They've got more important
matters to attend to.
Let's see what the University she went to (website) says about health care,
while there.

My suspicion is that your daughter's had other sprains and failed to get that
checked before she left for University. I have seen people here, who've had
sports injuries get checked before going travelling.
J
alex - 04 Jul 2006 20:50 GMT
I am a RN....... for 29 years.....the compression and stability that need
to be done by a doctor.  She had zero ankle injuries prior to leaving. She
had gone to see her Primary Care prior to leaving and  was given a clean
bill of health.

According to your standard ( living with a RN) she had as much knowledge as
your mother.
Steph - 05 Jul 2006 03:35 GMT
> "> Are you sure that they do?  I was under the impression that the
> majority
[quoted text clipped - 18 lines]
> care.  The Vast majority of Americans are very happy with the health
> system.

But there is only one pocket..........and the US health care system cost 16%
or 17% of the country's GDP. Most other western countries spend about 10% of
GDP

> The point of J's was that American's are over treated for cancer, ie that
> is why she brought up my mother which I thought was very cruel.  My mother
> and I were very close. It was a very painful time in my life. Imagine
> taking care of your aged father, dying mother and having 2 school age
> children. Steph continually bashes the way American oncologists treat
> patients

That isn't true at all. I know many excellent US oncologists. I also know
some who don't understand the difference between "best" and "most"

> The oncologists I have seen are very hard working and dedicated, if their
> sole motivation was money they would be in more lucrative field of
[quoted text clipped - 15 lines]
> system.  Although the University he is attending has a health clinic which
> gives me some hope that he won't be treated so cruelly as my daughter.

The UK isn't Australia
J - 04 Jul 2006 18:34 GMT
> I am really upset that my mother's story has been distorted.  I wonder how
> different my mother's situation would have been treated in Canada.  Once you
> have advance cancer do they just send you home to die?

No. My mother was kept in hospital. And given your story,  if my mother had had
thesame situation, in my opinion, she would have been kept in hospital and kept
comfortable for the rest of her days/life.

> Are palliative
> treatments ignored?   I fail to see how the "American Way was at fault".
[quoted text clipped - 21 lines]
> wonderful communicators in Canada? Are you telling me that the radiation
> doctor would have told us her palliative care was futile ?

In my opinion, you've just proven my point. A
We know now that cancer patients are prone to clots or bleeds. Whether you, as
an RN, knew that, at that time, I do not know.
I guess Steph would have to answer whether he would palliate a brain lesion.

J
alex - 04 Jul 2006 20:57 GMT
Steph opinion is meaningless, he did not examine my mother or have access to
her medical records. Her last days where at a health care facility, comfort
measures only.
"
> In my opinion, you've just proven my point. A
> We know now that cancer patients are prone to clots or bleeds. Whether
> you, as
> an RN, knew that, at that time, I do not know.

Of Course I knew......but it is very rare to have a massive GI Bleed, I am
basing this on the thousands of cases I have care for over the years.
I don't get your point.  In Canada would they have prevented her bleed?
Would they have euthanized her?  I don't get your point????
Do they have a magic machine able to predict when people die?  I was taking
care of my mother as a daughter, not in a professional role.
Only fools treat their own families, it is considered unethical and
unacceptable.

> I guess Steph would have to answer whether he would palliate a brain
> lesion.
>
> J
Steph - 05 Jul 2006 03:38 GMT
>> I am really upset that my mother's story has been distorted.  I wonder
>> how
[quoted text clipped - 51 lines]
>
> J

Patients with good performance status benefit from RT.
Patients who are very ill, or bedridden, don't.
I offer to irradiate the former, not the latter.
J - 05 Jul 2006 21:20 GMT
> "J" <analyse@invalid> wrote in message
>
[quoted text clipped - 32 lines]
> Patients who are very ill, or bedridden, don't.
> I offer to irradiate the former, not the latter.

Thanks Steph.
The sequence is kind of blurred in the quoted text.
She had a stroke, was in hospital recovering from and they found the brain
lesion, the lung cancer on CT and did RT.
She describes her as being "fragile", so in my book, that makes her the latter.
I don't think I would have given permission for RT (not then).

Hopefully this'll be the end of this thread if not the topic.
She'd just finished a similar one on the breast cancer newsgroup.

Oh, but I did mean to ask you, please. I know a lot of people who take
Prednisone.
Not one has mentioned gastric bleeding, but it's mentioned as a side effect.
http://www.rxlist.com/cgi/generic/pred_ad.htm
"Peptic ulcer with possible perforation and hemorrhage"
Dose related?
J
Steph - 06 Jul 2006 03:34 GMT
>> "J" <analyse@invalid> wrote in message
>>
[quoted text clipped - 57 lines]
> Dose related?
> J

Steroids can certainly cause bleeding. We often prescribe an H2 blocker like
pepcid for patients on steroids
alex - 08 Jul 2006 04:41 GMT
> Steroids can certainly cause bleeding. We often prescribe an H2 blocker
> like pepcid for patients on steroids

J....
You are revising history once again.....my mother never had a stroke.  I
said "  second night they where home, I got a call from the
police that I needed to pick up my father since my mother passed out and
probably had a stroke" ,  the American way is to have a diagnosis confirmed
by MD. It was Brain METS. Also my mother her whole life took prednisone ..I
said high dose steroids which was Decadron which is the drug of choice for
neuro issues.  And she was on H2 blockers, and according to the expert
"Steph" he would have radiated her since she was completely functional.  I
was referring to her medically fragile condition, meaning the radiation
oncologist expressed the fact that she would not live to complete the
therapy.  Prior and during radiation my mother was completely functional.

Can we let the dead live in peace? I don't see how the distorted discussion
of my mother's care has anything to do with cancer support.
Emily - 07 Jul 2006 02:29 GMT
analyse@invalid said...
> Oh, but I did mean to ask you, please. I know a lot of people who take
> Prednisone.
> Not one has mentioned gastric bleeding, but it's mentioned as a side effect.
> http://www.rxlist.com/cgi/generic/pred_ad.htm

Funny old world, isn't it.  Pred is also given to stave off gastric
bleeding and the like, insofar as it's a standard med given to folk with
IBD.  I suppose it's like antidepressants: some work for some people;
some make their condition worse.  It must be a tough call for doctors to
know when to prescribe it and when not.
Steph - 07 Jul 2006 03:37 GMT
> analyse@invalid said...
>> Oh, but I did mean to ask you, please. I know a lot of people who take
[quoted text clipped - 8 lines]
> some make their condition worse.  It must be a tough call for doctors to
> know when to prescribe it and when not.

When used for IBD, it still causes gastric bleeding, whatever its effects on
the large bowel
Emily - 07 Jul 2006 14:40 GMT
steph@vancouvers.island said...

> > analyse@invalid said...
> >> Oh, but I did mean to ask you, please. I know a lot of people who take
[quoted text clipped - 11 lines]
> When used for IBD, it still causes gastric bleeding, whatever its effects on
> the large bowel

It does?  Oo-er.  That must be very alarming for the patient and the
patient's carers.  My only experience of IBD is as the friend of a woman
whose young daughter started being affected when she was around 4 years
old - and it's also where I discovered medical support NGs, because my
friend didn't have 'net access so I was finding information for her.  
The IBDers I 'knew' back then were very like the folk here - very
helpful and friendly.  After a while I felt like I was part of a big
international family.  And as with here, no one really wants to be here
- but you sort of get attached to people...
Signature

Em

Figgertoes - 07 Jul 2006 03:54 GMT
> analyse@invalid said...
>> Oh, but I did mean to ask you, please. I know a lot of people who
[quoted text clipped - 7 lines]
> people; some make their condition worse.  It must be a tough call for
> doctors to know when to prescribe it and when not.

I was given an anti-depressant to help with sleep.  It gave me a noticable
lift, so I stayed with it several years.  Then I started feeling slow, like
I might be - well- depressed.  So I asked doc to wean me off to see & sure
enough, getting off gave me a huge lift. Hmmmmm

Fig, feeling more lively now
J - 07 Jul 2006 10:56 GMT
> analyse@invalid said...
> > Oh, but I did mean to ask you, please. I know a lot of people who take
[quoted text clipped - 7 lines]
> some make their condition worse.  It must be a tough call for doctors to
> know when to prescribe it and when not.

I was thinking of using my cat's leftovers...
They're only 5 mg and I need some oomph for car sanding.
J
Figgertoes - 07 Jul 2006 14:14 GMT
> I was thinking of using my cat's leftovers...
> They're only 5 mg and I need some oomph for car sanding.
> J

I had to read that a few times & then read back & put into context! I'm
sure you're joking, & I'm sure you know the potential dangers to the immune
system pred can cause.

You are sanding your car???  Sending oodles of oomph!!!  Hope it causes no
pain. I think there are attachments to an electric drill for that. I once
got a kit for buffing the haze off the finish of an older car I had -
attached to drill.  Music to sand cars by...now what would that be?   btw,
just noticed if you leave the 'd' off danger, it becomes anger.

Fig, wishing you a nice cool breeze & a big pitcher of iced tea
Figgertoes - 07 Jul 2006 14:23 GMT
Music to sand cars by...now what would
> that be?  

Reply to own post:

Lay on a Beach Boy's anthology - "She's so Fine my 409","Little Duce
Coupe."
Emily - 07 Jul 2006 22:52 GMT
me@privacy.net said...
> > I was thinking of using my cat's leftovers...
> > They're only 5 mg and I need some oomph for car sanding.
[quoted text clipped - 3 lines]
> sure you're joking, & I'm sure you know the potential dangers to the immune
> system pred can cause.

I had to read it a couple of times as well because I forgot we were
talking about prednisolone!  5mg isn't a very high dose Fig, so don't
panic.  I've got some soluble 5mg pills around somewhere for use in
asthmatic emergencies.  Actually, we haven't needed them for quite a
while, so they're probably out of date now...  We tend to dissolve 6
tablets in about 10ml water when necessary, followed by a phone call to
the doctor or local hospital.  Fingers crossed we won't need them for
another long time...

Signature

Em

Figgertoes - 08 Jul 2006 15:41 GMT
> me@privacy.net said...
>> > I was thinking of using my cat's leftovers...
[quoted text clipped - 13 lines]
> to the doctor or local hospital.  Fingers crossed we won't need them
> for another long time...

No panic here.  I gave them to my cat too for a long time (now he's taking
other things).  My mother took lots of it following 2 kidney transplants in
the 60s (chipmunk cheeks) I know pred has its place, but I avoid steroids -
had shot in knee as last resort before surgery since I had fantasy of
hiking with Socks right after he was diagnosed.  Worked for about a day.  
Didn't want to be decommissioned by surgery when it seemed his time was so
short.  

I can sure understand why you would take pred for asthma attack.  And I
hope you don't have any of those!

Fig
Emily - 08 Jul 2006 21:24 GMT
me@privacy.net said...

> > me@privacy.net said...
> >> > I was thinking of using my cat's leftovers...
[quoted text clipped - 24 lines]
> I can sure understand why you would take pred for asthma attack.  And I
> hope you don't have any of those!

I don't usually have to take it myself, but I keep some in stock for my
11 year old son whose flareups are rare but sudden and with little
warning.  The last occasion was when we tried to adopt a pair of kittens
from a local rescue centre.  One of them got on to T's bed... They
arrived here on the Friday evening and were gone again the following
Tuesday.  In the meantime T spent two nights in hospital having failed
to respond to a nebuliser.  I paid for their vaccinations as a sort of
compensation to the rescue centre because I felt so awful sending the
kittens back - but I really couldn't have a child made ill by their
presence.  Such a shame, they were dear little things.  That's life
though I guess :-(
Figgertoes - 05 Jul 2006 05:49 GMT
>> I am a breast cancer survivor but don't have metastic disease like
>> your mother.  I have heard from my oncologists that unlike many
[quoted text clipped - 32 lines]
>
> J

Socks had thought he was beginning another round of chemo when the
reports came back & his doctor told him no more treatment - time for
hospice. Kaiser, at least, knew when to fold 'em.  Socks knew himsef that
he had turned a corner about that time. We agreed with the doctor's call.

It was much different with my mother in the 60s.  I'm not clear about who
exactly didn't know when to stop, but, in retrospect, someone should have
several surgeries prior to her death. She never left the hospital after
they began the last round of endless, futile surgeries.

I don't know what about "The American Way."  Some obviously do get
overtreated.  Sometimes it's not clear if quality time lies ahead.  Socks
went through some bad times with 3-4 good days out of 7.  But then he'd
find another stretch of quality.  We were never sure what the next week
or month would bring, so we always seized those good times. We are
pleased with the medical treatment he received & are glad it supported
his going on as long as he could. I am equally glad they gave him
permission to stop when it became futile.

Fig
J - 05 Jul 2006 11:28 GMT
> I don't know what about "The American Way."  Some obviously do get
> overtreated.  Sometimes it's not clear if quality time lies ahead.  Socks
[quoted text clipped - 6 lines]
>
> Fig

Well Fig, you're talking about his end months...
he was not pounding chemo, one after the other before that.
He also posted that he had one liver lesion that reduced in size.
Here's his schedule again.

NSCLC (non small cell lung cancer)
http://groups-beta.google.com/group/alt.support.cancer/msg/7fa5ecdc08...

Socks    Sep 21 2004 :"This is from memory:

June 2001 - January 2002
Carbo and Taxol (10 treatments or so, every 3 weeks)

June 2002 - March 2003
Taxotere (every 3 weeks)

June 2003 - present
Zometa (every 3-4 weeks, still ongoing)

Jan 2004 - May 2004
Taxotere (6 treatments)
- - - - - - - - - - - - - - - - - - - - - -
He fared unusually well for someone diagnosed with Stage 4.
And I attribute that to he and his treating doctors knowing what to treat,
with what and when.

J
Figgertoes - 05 Jul 2006 13:49 GMT
>> I don't know what about "The American Way."  Some obviously do get
>> overtreated.  Sometimes it's not clear if quality time lies ahead.
[quoted text clipped - 11 lines]
> He also posted that he had one liver lesion that reduced in size.
> Here's his schedule again.

That liver lesion was an unwelcome holiday gift.  We had thought once the
liver got involved, he didn't have much time.  But he had that Christmas,
then another & through the summer of the next year.  Chemo made it
disappear from detection (although still present).  That's one reason
this forum is so valuable.  You learn that one person's story isn't
everyone's story. Treatments vary; responses vary. I was amazed & still
am at the degree to which cancer treatment is an art.

> NSCLC (non small cell lung cancer)
> http://groups-beta.google.com/group/alt.support.cancer/msg/7fa5ecdc08..
[quoted text clipped - 19 lines]
>
> J

And a fair amount of RT here & there.


We were very fortunate.  He also got wonderful support & information
here. He felt he knew many here very well, as I do now. I had not known
of ngs & was & am amazed at all one can learn here.  I feel only
tremendous gratitude.  Did I mention he rarely complained?  He rarely
complained.

Fig
J - 05 Jul 2006 16:22 GMT
> J <analyse@invalid> wrote in
>
[quoted text clipped - 10 lines]
> >
> > Well Fig, you're talking about his end months...

Afterthought, Fig, did you mean his end months or during his Taxol or each of
his chemos?
"Socks went through some bad times with 3-4 good days out of 7"
It was not clear.
J
figgertoes - 05 Jul 2006 22:24 GMT
> > J <analyse@invalid> wrote in
> >
[quoted text clipped - 9 lines]
> It was not clear.
> J
I really meant from the start - intermittently.  When we started the
adventure, we were constantly trying to 'take readings' to see if he
was getting better/worse.  And, of course, everyone around us wanted to
know how he was doing.  He got to know that 2nd day after chemo would
be a bad day & he should make no plans for that day.  But sometimes
he'd feel lousy/tired/sleepy for a good portion of a week.  We learned
not to draw conclusions from bad days/weeks because he continued to
rally & sometimes had very good weeks/months.  We moved 2 vacations up,
fearing he was getting too ill to travel - then he lived years longer
to take even more vacations.

It's difficult for someone of our personality types, but we found it
worked best not to try to analyze, predict so much.  While a certain
amount of information was useful, more information was not necessarily
better.

He predicted over & over that this was the last time he'd do this or
that.  Year after year he was (happily) wrong.

My point?  Just not to let even a series of bad days get you down or
make you think it's the beginning of the end.  It may be; it may not
be.  Sometimes doctors can tell; sometimes they can't.  Sometimes you
can tell; sometimes you can't.  That's just the way it is.

Fig
J - 07 Jul 2006 10:52 GMT
> J <analyse@invalid> wrote in news
>
[quoted text clipped - 12 lines]
> several surgeries prior to her death. She never left the hospital after
> they began the last round of endless, futile surgeries.

Sorry to hear this, Fig. ( ( ( hugs ) ) )

> I don't know what about "The American Way."  Some obviously do get
> overtreated.

we've heard a number of woeful situations, over the years.

> Sometimes it's not clear if quality time lies ahead.

Well, I don't know that "sspots all over the liver" necessarily cause
symptoms, but to me that indicates rapidly dividing cells...fast moving.
We'll have to see if she updates us.

> Socks
> went through some bad times with 3-4 good days out of 7.  But then he'd
[quoted text clipped - 3 lines]
> his going on as long as he could. I am equally glad they gave him
> permission to stop when it became futile.

Thanks for repeating, Fig. I absolutely know that some (even many) American
cancer patients get very good care.
J
Joy - 07 Jul 2006 23:31 GMT
> > Socks
> > went through some bad times with 3-4 good days out of 7.  But then he'd
[quoted text clipped - 7 lines]
> cancer patients get very good care.
> J

Most American cancer patients receive very good care!!
wizard10000@gmail.com - 05 Jul 2006 13:21 GMT
>...And Allan's wife's been on so many chemos now, she's got cumulative peripheral
> neuropathy, on high dose pain medications, yet he and the doctor continue to
> "plan her next treatment", and she has 4 bad days out of every 7 and the 7th is
> the treatment day.  We never hear a peep out of her (never posts). it's always
> him posting and he puts a positive spin on everything.  That's the American way.

Nothing in this post is true, J - but thanks for misleading everyone.
I normally don't post in this group any more but have made an exception
in this case.  You can find me over in alt.support.cancer.breast if
you'd like.

1.  Deborah doesn't have 'cumulative peripheral neuropathy'.  She has
peripheral neuropathy as a side effect of her current treatment - which
is Abraxane + Herceptin.

2.  She gets treatment every three weeks, not weekly.  She has 4 bad
days out of every 21, not 4 out of every 7.

3.  You never hear a peep out of her because she doesn't read Usenet.
I have my support resources, she has hers.  We respect each other's
privacy and both of us have 'safe areas' where we can vent that the
other doesn't read.

4.  I put a positive spin on things because Deborah's been a Stage IV
breast cancer survivor for seven years next month.  At dx her
oncologist gave her 6-12 months so she is indeed a medical miracle.
wizard10000@gmail.com - 05 Jul 2006 18:26 GMT
And - replying to my own post:

5.  She's not on 'high dose' pain meds.  She takes Lorcet for pain as
required - most days she doesn't take anything.
starfleet - 04 Jul 2006 02:37 GMT
J schreef:

> Hello Barbara and welcome to alt.support.cancer.
> I'm sorry to hear what's brought you here.
[quoted text clipped - 3 lines]
>
>  
I'm surprised that you are surprised. It's pretty common to suggest
chemo for breastcancerpatients with liver mets. Some do very well on the
regime and live for years.

Anne
Jonathan Law - 04 Jul 2006 07:13 GMT
Hi again, my mom is being treated for spots all over the liver.  3 months
ago her scans were clear, now shows up all over the liver.  Was first
diagnosed with Breast cancer 18 months ago, had a mastectomy, and 6 months
chemo, then 3 months ago it was found in the second breast, had her second
mastectomy, and now this.
We are all still feeling a little stunned by it all as it has been too much
in a short space of time.
Thanks
Barb

>> Hi there, I was wondering if anyone out there has had paclitaxol chemo
>> therapy, and if so, how it has affected you?  My mum has started it and
[quoted text clipped - 28 lines]
> Please stay with us, while we talk about this.
> J
J - 03 Jul 2006 17:04 GMT
> Hi there, I was wondering if anyone out there has had paclitaxol chemo
> therapy, and if so, how it has affected you?  My mum has started it and has
[quoted text clipped - 4 lines]
> Thanks in advance
> Barbara

Barbara,
Frankly I don't know what you mean by "knocked for a six".  An Australian
phrase that perhaps needs clarifying.
Some people have a life-threatening allergic reaction - it's usually stopped by
the physician, if so. (or it was for the cancer patient, I was recently
reading).

The (reported in cliniical trials) short and long term side effects of
paclitaxel  (Taxol) are mentioned here.  But clinical trials have inclusion and
exclusion criteria.
Clinically important side effects are in bold, italics
http://www.bccancer.bc.ca/HPI/DrugDatabase/DrugIndexPro/Paclitaxel.htm

This is an Australian (Adobe Acrobat file)
What you need to know before and while receiving Taxol
http://www.betterhealth.vic.gov.au/bhcv2/bhcmed.nsf/pages/bqctaxol/$File/bqctaxol.pdf

You know your mother more than we do; I encourage you to go with your mother
(or give a call if your mother's unable to go) to discuss it with the physician
who  who helped her decide the treatment plan.
Everybody's different.  There's different doses.

Keep in touch and let us know how you and she are doing, please.
J
Emily - 03 Jul 2006 23:42 GMT
analyse@invalid said...
> Frankly I don't know what you mean by "knocked for a six".  An Australian
> phrase that perhaps needs clarifying.

It means shocked, knocked the stuffing out of her, stunned, 'thrown for
a loop'.  It's probably a cricketing phrase, hence being easily
understood by a Brit; there are undoubtedly similar phrases (baseball?  
Is that played in Canada?) used elsewhere.

Signature

Em

J - 03 Jul 2006 23:43 GMT
> analyse@invalid said...
> > Frankly I don't know what you mean by "knocked for a six".  An Australian
[quoted text clipped - 4 lines]
> understood by a Brit; there are undoubtedly similar phrases (baseball?
> Is that played in Canada?) used elsewhere.

Well, yes, thanks Em, but not specific.
Maybe she's had a temporary drop in the number of white blood cells produced by
the bone marrow or blood pressure or liver may be temporarily affected, or
Taxol can sometimes cause a temporary slowing of the heart rate known as
bradycardia. This usually does not cause any harm.

http://www.cancerbackup.org.uk/Treatments/Chemotherapy/Individualdrugs/Paclitaxel

http://www.cancerhelp.org.uk/help/default.asp?page=4016#occ

Hard to know since she wasn't specific. That's why it's best she contact the
doctor, IMO.
J
Jonathan Law - 04 Jul 2006 07:04 GMT
Hi All, thanks for all the imput guys. The way Em, has discribed the
"knocked for a six" is the way I meant it, literally had the stuffing
knocked out of her.
Saw her oncologist today, says that the liver is looking worse rather than
any better so won't be giving her any more Taxol, but will try another
chemo - not sure what yet, will find out next week.
I know the future looks pretty bleak with this, but also believe where there
is life there is hope.  Only found out she had this 3 weeks ago and so are
still trying to come to terms with it all.
Thanks for the help.
Barb
Emily - 04 Jul 2006 14:25 GMT
lawfamily1@optusnet.com.au said...
> Hi All, thanks for all the imput guys. The way Em, has discribed the
> "knocked for a six" is the way I meant it, literally had the stuffing
[quoted text clipped - 7 lines]
> Thanks for the help.
> Barb

Have a shedload of {{{{{hugs}}}}}, Barb.  Liver cancer isn't good.  Chin
up and try to keep your sense of humour.  Honestly, I mean it.  Lose
your sense of the ridiculous and the absurd and you lose the battle.  
Retain it - and you've cleared a major hurdle.

Signature

Em
an Englishwoman living in Wales who (almost) understands cricket

J - 04 Jul 2006 19:46 GMT
> Hi All, thanks for all the imput guys. The way Em, has discribed the
> "knocked for a six" is the way I meant it, literally had the stuffing
[quoted text clipped - 5 lines]
> is life there is hope.  Only found out she had this 3 weeks ago and so are
> still trying to come to terms with it all.

I'm pleased to read that the oncologist is looking out for your mother's best
interests
Hugs
J
 
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